Katrin Kliche

Summary

Affiliation: University Hospital
Country: Germany

Publications

  1. doi request reprint Role of cellular mechanics in the function and life span of vascular endothelium
    Katrin Kliche
    Institute of Physiology II, University of Munster, Robert Koch Strasse 27b, Munster, Germany
    Pflugers Arch 462:209-17. 2011
  2. doi request reprint Long-term application of the aldosterone antagonist spironolactone prevents stiff endothelial cell syndrome
    Verena Drüppel
    Institute of Physiology II, University of Munster, Munster, Germany
    FASEB J 27:3652-9. 2013
  3. doi request reprint Membrane potential depolarization decreases the stiffness of vascular endothelial cells
    Chiara Callies
    Institute of Physiology II, University of Munster, Robert Koch Str 27b, 48149 Munster, Germany
    J Cell Sci 124:1936-42. 2011
  4. ncbi request reprint Endothelial sodium channels trigger endothelial salt sensitivity with aging
    Moritz Paar
    From the Institute of Physiology II M P, K K V, V D, H O and Department of Internal Medicine D H P, K K, University Hospital of Munster, Munster, Germany
    Hypertension 64:391-6. 2014
  5. pmc Salt overload damages the glycocalyx sodium barrier of vascular endothelium
    Hans Oberleithner
    Institute of Physiology II, University of Munster, Robert Koch Str 27b, 48149, Munster, Germany
    Pflugers Arch 462:519-28. 2011
  6. doi request reprint C-reactive protein makes human endothelium stiff and tight
    Kristina Kusche-Vihrog
    Institute of Physiology II, Muenster, Germany
    Hypertension 57:231-7. 2011

Collaborators

Detail Information

Publications6

  1. doi request reprint Role of cellular mechanics in the function and life span of vascular endothelium
    Katrin Kliche
    Institute of Physiology II, University of Munster, Robert Koch Strasse 27b, Munster, Germany
    Pflugers Arch 462:209-17. 2011
    ..This may explain the recently observed beneficial effects of spironolactone on the cardiovascular system. Taken together, the review highlights the importance of elasticity for normal endothelial function...
  2. doi request reprint Long-term application of the aldosterone antagonist spironolactone prevents stiff endothelial cell syndrome
    Verena Drüppel
    Institute of Physiology II, University of Munster, Munster, Germany
    FASEB J 27:3652-9. 2013
    ..This emphasizes the key role of vascular endothelium as a therapeutical target in cardiovascular disorders and might explain blood pressure independent actions of MR antagonism...
  3. doi request reprint Membrane potential depolarization decreases the stiffness of vascular endothelial cells
    Chiara Callies
    Institute of Physiology II, University of Munster, Robert Koch Str 27b, 48149 Munster, Germany
    J Cell Sci 124:1936-42. 2011
    ..This depolarization-induced decrease in the stiffness of endothelial cells could play a role in flow-mediated nitric-oxide-dependent vasodilation...
  4. ncbi request reprint Endothelial sodium channels trigger endothelial salt sensitivity with aging
    Moritz Paar
    From the Institute of Physiology II M P, K K V, V D, H O and Department of Internal Medicine D H P, K K, University Hospital of Munster, Munster, Germany
    Hypertension 64:391-6. 2014
    ..This mechanism might contribute to the development of age-related cardiovascular disease and suggests the usage of spironolactone and amiloride specifically in the elderly. ..
  5. pmc Salt overload damages the glycocalyx sodium barrier of vascular endothelium
    Hans Oberleithner
    Institute of Physiology II, University of Munster, Robert Koch Str 27b, 48149, Munster, Germany
    Pflugers Arch 462:519-28. 2011
    ..Damaged eGC facilitates sodium entry into the endothelial cells. This could explain endothelial dysfunction and arterial hypertension observed in sodium abuse...
  6. doi request reprint C-reactive protein makes human endothelium stiff and tight
    Kristina Kusche-Vihrog
    Institute of Physiology II, Muenster, Germany
    Hypertension 57:231-7. 2011
    ..The data indicate that CRP enhances the effects of aldosterone on the mechanical properties of the endothelium. Thus, CRP could counteract any decrease in arterial blood pressure that accompanies severe acute inflammatory processes...