Ingo Kleiter

Summary

Affiliation: University of Regensburg
Country: Germany

Publications

  1. ncbi request reprint Autonomic involvement in tick-borne encephalitis (TBE): report of five cases
    Ingo Kleiter
    Department of Neurology, University of Regensburg, Universitätsstr 84, D 93042 Regensburg, Germany
    Eur J Med Res 11:261-5. 2006
  2. pmc Smad7 in T cells drives T helper 1 responses in multiple sclerosis and experimental autoimmune encephalomyelitis
    Ingo Kleiter
    Department of Neurology, University Medical Centre Regensburg, Universitatsstrasse 84, 93053 Regensburg, Germany
    Brain 133:1067-81. 2010
  3. pmc Intraventricular cytarabine in a case of idiopathic hypertrophic pachymeningitis
    I Kleiter
    University of Regensburg, Department of Neurology, Universitatsstrasse 84, 93042 Regensburg, Germany
    J Neurol Neurosurg Psychiatry 75:1346-8. 2004
  4. ncbi request reprint Delayed humoral immunity in a patient with severe tick-borne encephalitis after complete active vaccination
    I Kleiter
    Dept of Neurology, University of Regensburg, Universitätsstr 84, 93042, Regensburg, Germany
    Infection 35:26-9. 2007
  5. pmc A lightning strike to the head causing a visual cortex defect with simple and complex visual hallucinations
    Ingo Kleiter
    Department of Neurology, University of Regensburg, Universitätsstr 84, 93042 Regensburg, Germany
    J Neurol Neurosurg Psychiatry 78:423-6. 2007
  6. doi request reprint Early changes on electroencephalography in natalizumab-associated progressive multifocal leucoencephalopathy
    Ingo Kleiter
    Department of Neurology, University Medical Center Regensburg, Germany
    Mult Scler 16:749-53. 2010
  7. pmc Aquaporin-4 antibody testing: direct comparison of M1-AQP4-DNA-transfected cells with leaky scanning versus M23-AQP4-DNA-transfected cells as antigenic substrate
    Sven Jarius
    Molecular Neuroimmunology, Department of Neurology, University of Heidelberg, Heidelberg, Germany
    J Neuroinflammation 11:129. 2014
  8. pmc Disease course and outcome of 15 monocentrically treated natalizumab-associated progressive multifocal leukoencephalopathy patients
    Stefanie Dahlhaus
    Department of Neurology, St Josef Hospital, Ruhr University Bochum, Bochum, Germany
    J Neurol Neurosurg Psychiatry 84:1068-74. 2013
  9. doi request reprint Visual evoked potentials in neuromyelitis optica and its spectrum disorders
    Marius Ringelstein
    Department of Neurology, Medical Faculty, Heinrich Heine University, Dusseldorf, Germany
    Mult Scler 20:617-20. 2014
  10. pmc Novel role for SLPI in MOG-induced EAE revealed by spinal cord expression analysis
    Andre M Mueller
    Department of Neurology, University of Regensburg, Franz Josef Strauss Allee 11, 93053 Regensburg, Germany
    J Neuroinflammation 5:20. 2008

Collaborators

Detail Information

Publications25

  1. ncbi request reprint Autonomic involvement in tick-borne encephalitis (TBE): report of five cases
    Ingo Kleiter
    Department of Neurology, University of Regensburg, Universitätsstr 84, D 93042 Regensburg, Germany
    Eur J Med Res 11:261-5. 2006
    ..Tick-borne encephalitis (TBE) is a viral infection of the CNS with significant acute and long-term morbidity. Dysfunction of the autonomic nervous system may be a potentially harmful complication of TBE...
  2. pmc Smad7 in T cells drives T helper 1 responses in multiple sclerosis and experimental autoimmune encephalomyelitis
    Ingo Kleiter
    Department of Neurology, University Medical Centre Regensburg, Universitatsstrasse 84, 93053 Regensburg, Germany
    Brain 133:1067-81. 2010
    ..Since a Smad7 deletion in T cells leads to immunosuppression, Smad7 may be a potential new therapeutic target in multiple sclerosis...
  3. pmc Intraventricular cytarabine in a case of idiopathic hypertrophic pachymeningitis
    I Kleiter
    University of Regensburg, Department of Neurology, Universitatsstrasse 84, 93042 Regensburg, Germany
    J Neurol Neurosurg Psychiatry 75:1346-8. 2004
    ....
  4. ncbi request reprint Delayed humoral immunity in a patient with severe tick-borne encephalitis after complete active vaccination
    I Kleiter
    Dept of Neurology, University of Regensburg, Universitätsstr 84, 93042, Regensburg, Germany
    Infection 35:26-9. 2007
    ..We report on a 54-year-old patient who had received his last booster vaccination 3 years before developing a severe TBE with delayed induction and longterm persistence of anti-TBEV-IgM-antibodies...
  5. pmc A lightning strike to the head causing a visual cortex defect with simple and complex visual hallucinations
    Ingo Kleiter
    Department of Neurology, University of Regensburg, Universitätsstr 84, 93042 Regensburg, Germany
    J Neurol Neurosurg Psychiatry 78:423-6. 2007
    ..Using the European Cooperation for Lightning Detection network, a meteorological system for lightning surveillance, the exact geographical location and nature of the lightning flash were retrospectively retraced...
  6. doi request reprint Early changes on electroencephalography in natalizumab-associated progressive multifocal leucoencephalopathy
    Ingo Kleiter
    Department of Neurology, University Medical Center Regensburg, Germany
    Mult Scler 16:749-53. 2010
    ..Functional neurological deficits may precede imaging features and should prompt early consideration of progressive multifocal leucoencephalopathy...
  7. pmc Aquaporin-4 antibody testing: direct comparison of M1-AQP4-DNA-transfected cells with leaky scanning versus M23-AQP4-DNA-transfected cells as antigenic substrate
    Sven Jarius
    Molecular Neuroimmunology, Department of Neurology, University of Heidelberg, Heidelberg, Germany
    J Neuroinflammation 11:129. 2014
    ..So-called cell-based assays (CBA) are thought to provide the best AQP4-Ab detection rates...
  8. pmc Disease course and outcome of 15 monocentrically treated natalizumab-associated progressive multifocal leukoencephalopathy patients
    Stefanie Dahlhaus
    Department of Neurology, St Josef Hospital, Ruhr University Bochum, Bochum, Germany
    J Neurol Neurosurg Psychiatry 84:1068-74. 2013
    ..We evaluated retrospectively 15 patients with natalizumab-associated PML treated at our centre...
  9. doi request reprint Visual evoked potentials in neuromyelitis optica and its spectrum disorders
    Marius Ringelstein
    Department of Neurology, Medical Faculty, Heinrich Heine University, Dusseldorf, Germany
    Mult Scler 20:617-20. 2014
    ..9% and a lack of response in 14.0% of NMO eyes. Delayed P100 latencies in eyes without prior ON suggested this was a subclinical affection. The data indicate heterogenous patterns in NMO, warranting further investigation...
  10. pmc Novel role for SLPI in MOG-induced EAE revealed by spinal cord expression analysis
    Andre M Mueller
    Department of Neurology, University of Regensburg, Franz Josef Strauss Allee 11, 93053 Regensburg, Germany
    J Neuroinflammation 5:20. 2008
    ....
  11. doi request reprint Activation of TGF-β-induced non-Smad signaling pathways during Th17 differentiation
    Maruf Hasan
    Department of Neurology, University Hospital Regensburg, Regensburg, Germany
    Immunol Cell Biol 93:662-72. 2015
    ..Finally, inhibitors of mitogen-activated protein kinase (MAPK) blocked in vitro polarization of Th17 cells. Our data show that Smad-dependent and -independent intracellular pathways contribute to murine Th17 differentiation. ..
  12. doi request reprint Retinal Involvement in a Patient with Cerebral Manifestation of Chronic Graft-Versus-Host-Disease
    Christiane Blecha
    Department of Ophthalmology, University Medical Center Regensburg, Germany
    Oncol Res Treat 38:532-4. 2015
    ..We report a 35-year-old female patient with cerebral manifestations of chronic graft-versus-host disease (cGvHD) and putative retinal involvement after allogeneic peripheral blood stem cell transplantation (alloHSCT)...
  13. pmc Update on the diagnosis and treatment of neuromyelitis optica: recommendations of the Neuromyelitis Optica Study Group (NEMOS)
    Corinna Trebst
    Department of Neurology, Hannover Medical School, Hannover, Germany
    J Neurol 261:1-16. 2014
    ..Promising new therapies are emerging in the form of anti-IL6 receptor, anti-complement or anti-AQP4-Ab biologicals. ..
  14. doi request reprint Long-term Therapy With Interleukin 6 Receptor Blockade in Highly Active Neuromyelitis Optica Spectrum Disorder
    Marius Ringelstein
    Department of Neurology, Heinrich Heine University Dusseldorf, Dusseldorf, Germany
    JAMA Neurol 72:756-63. 2015
    ..Interleukin 6, which is significantly elevated in serum and cerebrospinal fluid of patients with NMO, induces AQP4-ab production by plasmablasts and represents a novel therapeutic target...
  15. doi request reprint TGF-β signaling protects retinal neurons from programmed cell death during the development of the mammalian eye
    Barbara M Braunger
    Institute of Human Anatomy and Embryology, University of Regensburg, D 93053 Regensburg, Germany
    J Neurosci 33:14246-58. 2013
    ....
  16. ncbi request reprint Inhibition of Smad7, a negative regulator of TGF-beta signaling, suppresses autoimmune encephalomyelitis
    Ingo Kleiter
    Department of Neurology, University of Regensburg, Universitaetsstr 84, 93053 Regensburg, Germany
    J Neuroimmunol 187:61-73. 2007
    ..Smad7 inhibition thus represents a novel systemic treatment strategy for autoimmune CNS inflammation, targeting TGF-beta signaling without TGF-beta-associated toxicity...
  17. doi request reprint Heterozygous modulation of TGF-β signaling does not influence Müller glia cell reactivity or proliferation following NMDA-induced damage
    Martina Kugler
    Institute of Human Anatomy and Embryology, University of Regensburg, Regensburg, Germany
    Histochem Cell Biol 144:443-55. 2015
    ..Hence, TGF-β signaling in the retina might not be the essential causative factor to maintain mammalian Müller cells in a quiescent, non-proliferative state that prevents a stem cell-like function. ..
  18. pmc Analysis of neurogenesis during experimental autoimmune encephalomyelitis reveals pitfalls of bioluminescence imaging
    Ilya Ayzenberg
    Department of Neurology, St Josef Hospital, Ruhr University, Bochum, Germany
    PLoS ONE 10:e0118550. 2015
    ..Models with stable CNS-restricted luciferase expression could serve as technically convenient way to evaluate BBB integrity in a longitudinal manner. ..
  19. doi request reprint Entrapment syndrome of multiple nerves in graft-versus-host disease
    Ingo Kleiter
    Department of Neurology, St Josef Hospital, Ruhr University Bochum, 44791, Bochum, Germany
    Muscle Nerve 49:138-42. 2014
    ..Peripheral nerve entrapment syndromes are associated with hereditary neuropathy with liability to pressure palsies and a variety of rheumatic and endocrinological diseases...
  20. doi request reprint Interleukin 6 receptor blockade in patients with neuromyelitis optica nonresponsive to anti-CD20 therapy
    Ilya Ayzenberg
    Department of Neurology, St Josef Hospital, Ruhr University Bochum, Bochum, Germany
    JAMA Neurol 70:394-7. 2013
    ..To report first experiences with interleukin 6 receptor inhibition in therapy-resistant neuromyelitis optica (NMO)...
  21. doi request reprint Aquaporin 4 antibody positive central nervous system autoimmunity and multiple sclerosis are characterized by a distinct profile of antibodies to herpes viruses
    Johann Sellner
    Department of Neurology, Klinikum rechts der Isar, Technische Universitat Munchen, Munchen, Germany
    Neurochem Int 57:662-7. 2010
    ..Whether these findings reflect an epi-phenomenon of autoimmune disorders or indicate a disease-specific deregulated virus-host interaction needs to be examined in further studies...
  22. doi request reprint Present and Future Therapies in Neuromyelitis Optica Spectrum Disorders
    Ingo Kleiter
    Department of Neurology, St Josef Hospital, Ruhr University, Bochum, Germany
    Neurotherapeutics 13:70-83. 2016
    ..Current advances in immunopathological knowledge are translated into innovative concepts and begin a new era of NMOSD therapy. ..
  23. pmc Fluorodeoxyglucose positron emission tomography in anti-N-methyl-D-aspartate receptor encephalitis: distinct pattern of disease
    Frank Leypoldt
    Department of Neurology, University Medical Center Eppendorf, Martinistr 52, Hamburg, Germany
    J Neurol Neurosurg Psychiatry 83:681-6. 2012
    ..However, a common pattern of FDG-PET abnormalities has not been reported...
  24. doi request reprint Failure of natalizumab to prevent relapses in neuromyelitis optica
    Ingo Kleiter
    Department of Neurology, University Medical Center Regensburg, Regensburg, Germany
    Arch Neurol 69:239-45. 2012
    ..To describe first experiences with the integrin inhibitor natalizumab, given to patients with suspected relapsing-remitting multiple sclerosis (MS) who were later diagnosed with aquaporin 4-positive neuromyelitis optica (NMO)...
  25. ncbi request reprint Targeting fibroblast growth factor-inducible-14 signaling protects from chronic relapsing experimental autoimmune encephalomyelitis
    A M Mueller
    Department of Neurology, University of Regensburg, Universitaetsstr 84, 93053 Regensburg, Germany
    J Neuroimmunol 159:55-65. 2005
    ..Purified IgG from TWEAK- or Fn14-vaccinated rats prevented TWEAK-induced production of CCL2 by endothelial cells. Blocking Fn14 signaling represents a novel approach with potential for the treatment of CNS autoimmunity...