Britta Kleist

Summary

Affiliation: University of Greifswald
Country: Germany

Publications

  1. ncbi request reprint Detection of new PTEN/MMAC1 mutations in head and neck squamous cell carcinomas with loss of chromosome 10
    Micaela Poetsch
    Institute of Forensic Medicine, Ernst Moritz Arndt University, Kuhstrasse 30, D 17489, Greifswald, Germany
    Cancer Genet Cytogenet 132:20-4. 2002
  2. ncbi request reprint Loss of heterozygosity at 15q21.3 correlates with occurrence of metastases in head and neck cancer
    Micaela Poetsch
    Institute of Forensic Medicine, University of Greifswald, Greifswald, Germany
    Mod Pathol 19:1462-9. 2006
  3. ncbi request reprint Epithelial-myoepithelial carcinoma of the parotid gland-evidence of contrasting DNA patterns in two different histological parts
    Britta Kleist
    Institute of Pathology, Ernst Moritz Arndt University, F Loeffler Strasse 23e, 17489, Greifswald, Germany
    Virchows Arch 442:585-90. 2003
  4. ncbi request reprint Intranodal palisaded myofibroblastoma with overexpression of cyclin D1
    Britta Kleist
    Institutes of Pathology, Ernst Moritz Arndt University, Greifswald, Germany
    Arch Pathol Lab Med 127:1040-3. 2003
  5. ncbi request reprint The supplementary diagnostic power of selected immunohistochemical, molecular genetic and infective parameters in epithelial hyperplastic laryngeal lesions
    Britta Kleist
    Institute of Pathology, University of Greifswald, Greifswald, Germany
    Oncology 65:347-54. 2003
  6. ncbi request reprint Basaloid in contrast to nonbasaloid head and neck squamous cell carcinomas display aberrations especially in cell cycle control genes
    Micaela Poetsch
    Institute of Forensic Medicine, Ernst Moritz Arndt University, Kuhstrasse 30, D 17489 Greifswald, Germany
    Head Neck 25:904-10. 2003
  7. ncbi request reprint Different risk factors in basaloid and common squamous head and neck cancer
    Britta Kleist
    Institutes of Pathology, University of Greifswald, Greifswald, Germany
    Laryngoscope 114:1063-8. 2004
  8. ncbi request reprint Divergent patterns of allelic alterations in premalignant laryngeal lesions indicate differences in the impact of morphological grading characteristics
    Britta Kleist
    Institute of Pathology, University of Greifswald, Greifswald, Germany
    Oncology 67:420-7. 2004
  9. ncbi request reprint Relationship between mitochondrial DNA instability, mitochondrial DNA large deletions, and nuclear microsatellite instability in head and neck squamous cell carcinomas
    Micaela Poetsch
    Institute of Forensic Medicine, University of Greifswald, Germany
    Diagn Mol Pathol 13:26-32. 2004
  10. ncbi request reprint Screening of microsatellite markers in penile cancer reveals differences between metastatic and nonmetastatic carcinomas
    Micaela Poetsch
    Institute of Forensic Medicine, University of Greifswald, Greifswald, Germany
    Mod Pathol 20:1069-77. 2007

Collaborators

Detail Information

Publications14

  1. ncbi request reprint Detection of new PTEN/MMAC1 mutations in head and neck squamous cell carcinomas with loss of chromosome 10
    Micaela Poetsch
    Institute of Forensic Medicine, Ernst Moritz Arndt University, Kuhstrasse 30, D 17489, Greifswald, Germany
    Cancer Genet Cytogenet 132:20-4. 2002
    ..Our results focus on the essential but not solitary role of PTEN/MMAC1 in the tumorigenesis or progression of a subset of HNSCC...
  2. ncbi request reprint Loss of heterozygosity at 15q21.3 correlates with occurrence of metastases in head and neck cancer
    Micaela Poetsch
    Institute of Forensic Medicine, University of Greifswald, Greifswald, Germany
    Mod Pathol 19:1462-9. 2006
    ..Our data hint at aberrations in 15q21.3 as a possible important characteristic for head and neck squamous cell carcinomas with risk of progression...
  3. ncbi request reprint Epithelial-myoepithelial carcinoma of the parotid gland-evidence of contrasting DNA patterns in two different histological parts
    Britta Kleist
    Institute of Pathology, Ernst Moritz Arndt University, F Loeffler Strasse 23e, 17489, Greifswald, Germany
    Virchows Arch 442:585-90. 2003
    ..Nevertheless, our results provoke a discussion, whether these genetic alterations could be considered as determinants of histologically and prognostically divergent types in EMC...
  4. ncbi request reprint Intranodal palisaded myofibroblastoma with overexpression of cyclin D1
    Britta Kleist
    Institutes of Pathology, Ernst Moritz Arndt University, Greifswald, Germany
    Arch Pathol Lab Med 127:1040-3. 2003
    ..Nevertheless, our results point to the cell cycle regulatory genes as a factor in the pathogenesis of IPM...
  5. ncbi request reprint The supplementary diagnostic power of selected immunohistochemical, molecular genetic and infective parameters in epithelial hyperplastic laryngeal lesions
    Britta Kleist
    Institute of Pathology, University of Greifswald, Greifswald, Germany
    Oncology 65:347-54. 2003
    ....
  6. ncbi request reprint Basaloid in contrast to nonbasaloid head and neck squamous cell carcinomas display aberrations especially in cell cycle control genes
    Micaela Poetsch
    Institute of Forensic Medicine, Ernst Moritz Arndt University, Kuhstrasse 30, D 17489 Greifswald, Germany
    Head Neck 25:904-10. 2003
    ..At present, the differences between head and neck basaloid squamous cell carcinoma (BSCC) and nonbasaloid squamous cell carcinoma (SCC) are mostly on the basis of histologic and immunohistologic findings...
  7. ncbi request reprint Different risk factors in basaloid and common squamous head and neck cancer
    Britta Kleist
    Institutes of Pathology, University of Greifswald, Greifswald, Germany
    Laryngoscope 114:1063-8. 2004
    ..The prevalence of human papillomavirus (HPV), herpes simplex virus (HSV), cigarette smoking and alcohol abuse was compared between two histological subgroups of head and neck cancer...
  8. ncbi request reprint Divergent patterns of allelic alterations in premalignant laryngeal lesions indicate differences in the impact of morphological grading characteristics
    Britta Kleist
    Institute of Pathology, University of Greifswald, Greifswald, Germany
    Oncology 67:420-7. 2004
    ....
  9. ncbi request reprint Relationship between mitochondrial DNA instability, mitochondrial DNA large deletions, and nuclear microsatellite instability in head and neck squamous cell carcinomas
    Micaela Poetsch
    Institute of Forensic Medicine, University of Greifswald, Germany
    Diagn Mol Pathol 13:26-32. 2004
    ..527 and 0.078, respectively). Nevertheless, the high rate of mtMSI suggests an involvement of mtDNA alterations in the tumorigenesis of this head and neck cancer and supports the proposal that this aberration may be a new tumor marker...
  10. ncbi request reprint Screening of microsatellite markers in penile cancer reveals differences between metastatic and nonmetastatic carcinomas
    Micaela Poetsch
    Institute of Forensic Medicine, University of Greifswald, Greifswald, Germany
    Mod Pathol 20:1069-77. 2007
    ..These regions are worthy for further analysis concerning tumor suppressor genes and metastasis suppressor genes...
  11. ncbi request reprint Evaluation of allelic alterations in short tandem repeats in different kinds of solid tumors--possible pitfalls in forensic casework
    Micaela Poetsch
    Institute of Forensic Medicine, Ernst Moritz Arndt Universitat, Kuhstrasse 30, D 17489 Greifswald, Germany
    Forensic Sci Int 145:1-6. 2004
    ..Our results demonstrate that the use of tumor tissue in forensic identification and paternity testing is questionable, especially if only tumors with known microsatellite instability are available...
  12. ncbi request reprint Cecal ligation and puncture versus colon ascendens stent peritonitis: two distinct animal models for polymicrobial sepsis
    Stefan Maier
    Department of Surgery, Ernst Moritz Arndt Universitat, Greifswald, Germany
    Shock 21:505-11. 2004
    ..In contrast, CLP reveals a model of intra-abdominal abscess formation with sustained and minor signs of systemic inflammation...
  13. pmc Loss of heterozygosity occurs predominantly, but not exclusively, in the epithelial compartment of pleomorphic adenoma
    Micaela Poetsch
    Institute of Forensic Medicine, University of Greifswald, Greifswald, Germany
    Neoplasia 7:688-95. 2005
    ..Our data give further evidence that alterations in 8q may be an early event in PA tumorigenesis, whereas LOH in 12q may characterize cells with the potential to transform in CXPAs...
  14. ncbi request reprint Comparative proteomic analysis of neoplastic and non-neoplastic germ cell tissue
    Uwe Zimmermann
    Department of Urology, University of Greifswald, Fleischmannstr 42 44, D 17487 Greifswald, Germany
    Biol Chem 387:437-40. 2006
    ..This expression difference could also be observed at the mRNA level, implying neoplasm-associated alterations in transcriptional or post-transcriptional mechanisms...