Research Topics
Species | Britta KleistSummaryAffiliation: University of Greifswald Country: Germany Publications
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Detail Information
Publications
Detection of new PTEN/MMAC1 mutations in head and neck squamous cell carcinomas with loss of chromosome 10Micaela Poetsch
Institute of Forensic Medicine, Ernst Moritz Arndt University, Kuhstrasse 30, D 17489, Greifswald, Germany
Cancer Genet Cytogenet 132:20-4. 2002..Our results focus on the essential but not solitary role of PTEN/MMAC1 in the tumorigenesis or progression of a subset of HNSCC...- Loss of heterozygosity at 15q21.3 correlates with occurrence of metastases in head and neck cancerMicaela Poetsch
Institute of Forensic Medicine, University of Greifswald, Greifswald, Germany
Mod Pathol 19:1462-9. 2006..Our data hint at aberrations in 15q21.3 as a possible important characteristic for head and neck squamous cell carcinomas with risk of progression... - Epithelial-myoepithelial carcinoma of the parotid gland-evidence of contrasting DNA patterns in two different histological partsBritta Kleist
Institute of Pathology, Ernst Moritz Arndt University, F Loeffler Strasse 23e, 17489, Greifswald, Germany
Virchows Arch 442:585-90. 2003..Nevertheless, our results provoke a discussion, whether these genetic alterations could be considered as determinants of histologically and prognostically divergent types in EMC... - Intranodal palisaded myofibroblastoma with overexpression of cyclin D1Britta Kleist
Institutes of Pathology, Ernst Moritz Arndt University, Greifswald, Germany
Arch Pathol Lab Med 127:1040-3. 2003..Nevertheless, our results point to the cell cycle regulatory genes as a factor in the pathogenesis of IPM... - The supplementary diagnostic power of selected immunohistochemical, molecular genetic and infective parameters in epithelial hyperplastic laryngeal lesionsBritta Kleist
Institute of Pathology, University of Greifswald, Greifswald, Germany
Oncology 65:347-54. 2003.... - Basaloid in contrast to nonbasaloid head and neck squamous cell carcinomas display aberrations especially in cell cycle control genesMicaela Poetsch
Institute of Forensic Medicine, Ernst Moritz Arndt University, Kuhstrasse 30, D 17489 Greifswald, Germany
Head Neck 25:904-10. 2003..At present, the differences between head and neck basaloid squamous cell carcinoma (BSCC) and nonbasaloid squamous cell carcinoma (SCC) are mostly on the basis of histologic and immunohistologic findings... - Different risk factors in basaloid and common squamous head and neck cancerBritta Kleist
Institutes of Pathology, University of Greifswald, Greifswald, Germany
Laryngoscope 114:1063-8. 2004..The prevalence of human papillomavirus (HPV), herpes simplex virus (HSV), cigarette smoking and alcohol abuse was compared between two histological subgroups of head and neck cancer... - Divergent patterns of allelic alterations in premalignant laryngeal lesions indicate differences in the impact of morphological grading characteristicsBritta Kleist
Institute of Pathology, University of Greifswald, Greifswald, Germany
Oncology 67:420-7. 2004.... - Relationship between mitochondrial DNA instability, mitochondrial DNA large deletions, and nuclear microsatellite instability in head and neck squamous cell carcinomasMicaela Poetsch
Institute of Forensic Medicine, University of Greifswald, Germany
Diagn Mol Pathol 13:26-32. 2004..527 and 0.078, respectively). Nevertheless, the high rate of mtMSI suggests an involvement of mtDNA alterations in the tumorigenesis of this head and neck cancer and supports the proposal that this aberration may be a new tumor marker... - Screening of microsatellite markers in penile cancer reveals differences between metastatic and nonmetastatic carcinomasMicaela Poetsch
Institute of Forensic Medicine, University of Greifswald, Greifswald, Germany
Mod Pathol 20:1069-77. 2007..These regions are worthy for further analysis concerning tumor suppressor genes and metastasis suppressor genes... - Evaluation of allelic alterations in short tandem repeats in different kinds of solid tumors--possible pitfalls in forensic caseworkMicaela Poetsch
Institute of Forensic Medicine, Ernst Moritz Arndt Universitat, Kuhstrasse 30, D 17489 Greifswald, Germany
Forensic Sci Int 145:1-6. 2004..Our results demonstrate that the use of tumor tissue in forensic identification and paternity testing is questionable, especially if only tumors with known microsatellite instability are available... - Cecal ligation and puncture versus colon ascendens stent peritonitis: two distinct animal models for polymicrobial sepsisStefan Maier
Department of Surgery, Ernst Moritz Arndt Universitat, Greifswald, Germany
Shock 21:505-11. 2004..In contrast, CLP reveals a model of intra-abdominal abscess formation with sustained and minor signs of systemic inflammation... 
Loss of heterozygosity occurs predominantly, but not exclusively, in the epithelial compartment of pleomorphic adenomaMicaela Poetsch
Institute of Forensic Medicine, University of Greifswald, Greifswald, Germany
Neoplasia 7:688-95. 2005..Our data give further evidence that alterations in 8q may be an early event in PA tumorigenesis, whereas LOH in 12q may characterize cells with the potential to transform in CXPAs...- Comparative proteomic analysis of neoplastic and non-neoplastic germ cell tissueUwe Zimmermann
Department of Urology, University of Greifswald, Fleischmannstr. 42-44, D-17487 Greifswald, Germany
Biol Chem 387:437-40. 2006..This expression difference could also be observed at the mRNA level, implying neoplasm-associated alterations in transcriptional or post-transcriptional mechanisms...