Tilo T Kircher

Summary

Affiliation: University Hospital
Country: Germany

Publications

  1. ncbi request reprint The neural correlates of intentional and incidental self processing
    Tilo T J Kircher
    University of Tuebingen, Department of Psychiatry, Osianderstrasse 24, D 72076 Tubingen, Germany
    Neuropsychologia 40:683-92. 2002
  2. ncbi request reprint Neural correlates of metaphor processing in schizophrenia
    Tilo T J Kircher
    Department of Psychiatry and Psychotherapy, RWTH Aachen University, Pauwelsstr 30, D 52074 Aachen, Germany
    Neuroimage 34:281-9. 2007
  3. ncbi request reprint Metacognition and reflexivity in patients with schizophrenia
    Tilo T J Kircher
    Department of Psychiatry and Psychotherapy, RWTH Aachen University, Aachen, Germany
    Psychopathology 40:254-60. 2007
  4. pmc Hippocampal activation in patients with mild cognitive impairment is necessary for successful memory encoding
    Tilo T Kircher
    Department of Neurology, RWTH Aachen, Pauwelsstr 30, D 52074 Aachen, Germany
    J Neurol Neurosurg Psychiatry 78:812-8. 2007
  5. ncbi request reprint Neural correlates of syntax production in schizophrenia
    Tilo T J Kircher
    Department of Psychiatry, University of Aachen, Pauwelstrasse 30, D 52076 Aachen, Germany
    Br J Psychiatry 186:209-14. 2005
  6. doi request reprint Hippocampal dysfunction during free word association in male patients with schizophrenia
    Tilo Kircher
    Department of Psychiatry, RWTH Aachen University, Pauwelsstr 30, D 52074 Aachen, Germany
    Schizophr Res 101:242-55. 2008
  7. ncbi request reprint [Integrated treatment of depression in Aachen]
    T Kirchner
    Klinik fur Psychiatrie und Psychotherapie, Universitatsklinikum Aachen, Pauwelsstrasse 30, 52074 Aachen
    Nervenarzt 77:1399-403. 2006
  8. ncbi request reprint Functional brain imaging of symptoms and cognition in schizophrenia
    Tilo T J Kircher
    Department of Psychiatry and Psychotherapy, University of Aachen, Pauwelsstrasse 30, D 52074 Aachen, Germany
    Prog Brain Res 150:299-308. 2005
  9. ncbi request reprint Cortical activation during cholinesterase-inhibitor treatment in Alzheimer disease: preliminary findings from a pharmaco-fMRI study
    Tilo T J Kircher
    Dept of Psychiatry, Univ of Tübingen, Tubingen, Germany
    Am J Geriatr Psychiatry 13:1006-13. 2005
  10. ncbi request reprint Self-face recognition in schizophrenia
    Tilo T Kircher
    Department of Psychiatry and Psychotherapy, RWTH Aachen University, Pauwelsstrasse 30, D 52074 Aachen, Germany
    Schizophr Res 94:264-72. 2007

Detail Information

Publications35

  1. ncbi request reprint The neural correlates of intentional and incidental self processing
    Tilo T J Kircher
    University of Tuebingen, Department of Psychiatry, Osianderstrasse 24, D 72076 Tubingen, Germany
    Neuropsychologia 40:683-92. 2002
    ....
  2. ncbi request reprint Neural correlates of metaphor processing in schizophrenia
    Tilo T J Kircher
    Department of Psychiatry and Psychotherapy, RWTH Aachen University, Pauwelsstr 30, D 52074 Aachen, Germany
    Neuroimage 34:281-9. 2007
    ..Although this is routinely tested during clinical interview, its neural basis is unknown...
  3. ncbi request reprint Metacognition and reflexivity in patients with schizophrenia
    Tilo T J Kircher
    Department of Psychiatry and Psychotherapy, RWTH Aachen University, Aachen, Germany
    Psychopathology 40:254-60. 2007
    ..Many patients with schizophrenia demonstrate a lack of insight into their disorder and often do not complain about their cognitive impairments. This might be due to generally reduced metacognitive abilities...
  4. pmc Hippocampal activation in patients with mild cognitive impairment is necessary for successful memory encoding
    Tilo T Kircher
    Department of Neurology, RWTH Aachen, Pauwelsstr 30, D 52074 Aachen, Germany
    J Neurol Neurosurg Psychiatry 78:812-8. 2007
    ..Episodic memory enables us to consciously recollect personally experienced past events. Memory performance is reduced in patients with mild cognitive impairment (MCI), an at-risk condition for Alzheimer's disease (AD)...
  5. ncbi request reprint Neural correlates of syntax production in schizophrenia
    Tilo T J Kircher
    Department of Psychiatry, University of Aachen, Pauwelstrasse 30, D 52076 Aachen, Germany
    Br J Psychiatry 186:209-14. 2005
    ..The production of grammatically complex sentences is impaired in schizophrenia. It has been suggested that impaired syntax processing reflects a risk for the disorder...
  6. doi request reprint Hippocampal dysfunction during free word association in male patients with schizophrenia
    Tilo Kircher
    Department of Psychiatry, RWTH Aachen University, Pauwelsstr 30, D 52074 Aachen, Germany
    Schizophr Res 101:242-55. 2008
    ..The hippocampus seems to play a major role in word generation. In schizophrenia, attenuated hippocampal activity during semantic tasks strengthens the hypothesis of impaired relational memory processes, affecting thought and language...
  7. ncbi request reprint [Integrated treatment of depression in Aachen]
    T Kirchner
    Klinik fur Psychiatrie und Psychotherapie, Universitatsklinikum Aachen, Pauwelsstrasse 30, 52074 Aachen
    Nervenarzt 77:1399-403. 2006
  8. ncbi request reprint Functional brain imaging of symptoms and cognition in schizophrenia
    Tilo T J Kircher
    Department of Psychiatry and Psychotherapy, University of Aachen, Pauwelsstrasse 30, D 52074 Aachen, Germany
    Prog Brain Res 150:299-308. 2005
    ..We also characterize the neural networks involved in their emotional and cognitive dysfunction...
  9. ncbi request reprint Cortical activation during cholinesterase-inhibitor treatment in Alzheimer disease: preliminary findings from a pharmaco-fMRI study
    Tilo T J Kircher
    Dept of Psychiatry, Univ of Tübingen, Tubingen, Germany
    Am J Geriatr Psychiatry 13:1006-13. 2005
    ..The authors studied, with functional magnetic resonance imaging (fMRI), the neural mechanism by which this cholinergic enhancement improves memory encoding in AD over longer time periods...
  10. ncbi request reprint Self-face recognition in schizophrenia
    Tilo T Kircher
    Department of Psychiatry and Psychotherapy, RWTH Aachen University, Pauwelsstrasse 30, D 52074 Aachen, Germany
    Schizophr Res 94:264-72. 2007
    ..In this study, the ability to recognize the own face as an indicator of certain aspects of self-awareness was investigated in patients with schizophrenia...
  11. ncbi request reprint A randomised trial of a geriatric evaluation and management consultation services in frail hospitalised patients
    Tilo T J Kircher
    Department of Psychiatry, University of Tubingen, Osianderstr 24, D 72076 Tubingen, Germany
    Age Ageing 36:36-42. 2007
    ..We examined whether an inpatient geriatric consultation service might be beneficial in a country with a social welfare system...
  12. doi request reprint Anterior hippocampus orchestrates successful encoding and retrieval of non-relational memory: an event-related fMRI study
    Tilo Kircher
    Department of Psychiatry, RWTH Aachen University Hospital, Pauwelsstr 30, 52074, Aachen, Germany
    Eur Arch Psychiatry Clin Neurosci 258:363-72. 2008
    ..Our results indicate that the anterior left hippocampus plays an important role during successful memory encoding and during successful memory retrieval in a task of simple, non-associative wordlist learning in healthy elderly subjects...
  13. doi request reprint [Neurobiological foundations of thought and language disorder in schizophrenia]
    T Kircher
    Universitatsklinik fur Psychiatrie und Psychotherapie, RWTH Aachen, Germany
    Fortschr Neurol Psychiatr 76:S24-32. 2008
    ..Taken together, there is much evidence that the lateral temporal lobes bilaterally are predominantly involved in the generation of positive formal thought disorder in schizophrenia...
  14. doi request reprint Neural interaction of speech and gesture: differential activations of metaphoric co-verbal gestures
    Tilo Kircher
    Department of Psychiatry and Psychotherapy, RWTH Aachen University, Pauwelsstr 30, D 52074 Aachen, Germany
    Neuropsychologia 47:169-79. 2009
    ..Speech related gestures seem to enhance language comprehension during the face-to-face communication...
  15. doi request reprint Neuregulin 1 ICE-single nucleotide polymorphism in first episode schizophrenia correlates with cerebral activation in fronto-temporal areas
    Tilo Kircher
    Dept of Psychiatry and Psychotherapy RWTH, University of Aachen, Pauwelsstr 30, 52074, Aachen, Germany
    Eur Arch Psychiatry Clin Neurosci 259:72-9. 2009
    ..Heterogeneity of structural and functional measures within patients characterized by clinical phenotypes may be in part due to this genetic variation...
  16. doi request reprint Neural correlates of verbal episodic memory in patients with MCI and Alzheimer's disease--a VBM study
    Dirk T Leube
    Department of Psychiatry, University Hospital Aachen, Pauwelsstrasse 30, Aachen, Germany
    Int J Geriatr Psychiatry 23:1114-8. 2008
    ..Hippocampal atrophy is a hallmark feature of Alzheimer's disease (AD). We used a new and automatized morphometric technique to better characterize brain atrophy in subjects with different levels of cognitive deficit...
  17. ncbi request reprint Mild cognitive impairment (MCI) and actual retrieval performance affect cerebral activation in the elderly
    Reinhard Heun
    Department of Psychiatry, University of Bonn, Sigmund Freud Strasse 25, 53105 Bonn, Germany
    Neurobiol Aging 28:404-13. 2007
    ..Activation differences between response categories might reflect success (hits) and effort (misses). Increased retrieval-related activation may be used as early marker in subjects at risk of Alzheimer's disease...
  18. doi request reprint Cerebral dysfunctions of emotion-cognition interactions in adolescent-onset schizophrenia
    Katharina Pauly
    Department of Psychiatry and Psychotherapy, RWTH Aachen University, Aachen, Germany
    J Am Acad Child Adolesc Psychiatry 47:1299-310. 2008
    ..In this study, possible dysfunctions of the neural correlates underlying the interaction of negative emotion and working memory in AOS were investigated...
  19. doi request reprint The interaction of working memory and emotion in persons clinically at risk for psychosis: an fMRI pilot study
    Katharina Pauly
    Department of Psychiatry and Psychotherapy, RWTH Aachen University, Pauwelsstr 30, 52074 Aachen, Germany
    Schizophr Res 120:167-76. 2010
    ..Our study underlines that cerebral dysfunctions related to cognitive and emotional processes, as well as their interaction, can emerge in persons with CHR, even in absence of behavioral differences...
  20. ncbi request reprint Laterality in metaphor processing: lack of evidence from functional magnetic resonance imaging for the right hemisphere theory
    Alexander M Rapp
    Department of Psychiatry, University of Tuebingen, Osianderstrasse 24, 72076 Tuebingen, Germany
    Brain Lang 100:142-9. 2007
    ..The lowest degree of laterality was found in the temporal pole. Other factors than metaphoricity per se might trigger right hemisphere recruitment. Results are discussed in the context of lesion and hemifield studies...
  21. ncbi request reprint Observing one's hand become anarchic: an fMRI study of action identification
    Dirk T Leube
    Department of Psychiatry, University of Tuebingen, Osianderstr 24, 72076 Tuebingen, Germany
    Conscious Cogn 12:597-608. 2003
    ..A right fronto-parietal network was selectively active during a sudden mismatch between one's own observed and performed hand action...
  22. ncbi request reprint Self-consciousness, self-agency, and schizophrenia
    Tilo T J Kircher
    Department of Psychiatry, University of Tubingen, Tubingen, Germany
    Conscious Cogn 12:656-69. 2003
    ..We argue, that self-consciousness is a valid construct and can be studied with the instruments of cognitive and neuroscience...
  23. ncbi request reprint Pausing for thought: engagement of left temporal cortex during pauses in speech
    Tilo T J Kircher
    Department of Psychiatry, University of Tuebingen, Tubingen, Germany
    Neuroimage 21:84-90. 2004
    ..The latter finding is consistent with evidence that within-clause pauses are a correlate of speech planning and in particular lexical retrieval...
  24. ncbi request reprint Neural correlates of metaphor processing
    Alexander M Rapp
    Department of Psychiatry, University of Tuebingen, Osianderstrasse 24, D 72076 Tuebingen, Germany
    Brain Res Cogn Brain Res 20:395-402. 2004
    ..Previous results of a right hemispheric involvement in metaphor processing might reflect understanding of complex sentences...
  25. ncbi request reprint Brain regions sensitive to the face inversion effect: a functional magnetic resonance imaging study in humans
    Dirk T Leube
    Department of Psychiatry, University of Tuebingen, Osianderstrasse 24, 72076, Tuebingen, Germany
    Neurosci Lett 342:143-6. 2003
    ..For this differential contrast, we found a signal change in the right superior temporal sulcus and right insula. Configural properties are processed in a network comprising right superior temporal and insular cortex...
  26. ncbi request reprint Successful episodic memory retrieval of newly learned faces activates a left fronto-parietal network
    Dirk T Leube
    Department of Psychiatry, University of Tuebingen, Osianderstr 24, 72076 Tuebingen, Germany
    Brain Res Cogn Brain Res 18:97-101. 2003
    ....
  27. doi request reprint Age-related changes in parietal lobe activation during an episodic memory retrieval task
    Christiane S H Oedekoven
    Department of Psychiatry and Psychotherapy, Clinic of Psychiatry and Psychotherapy, Philipps University Marburg, Rudolf Bultmann Straße 8, Marburg 35039, Germany
    J Neural Transm 120:799-806. 2013
    ..In the elderly, the overall stronger activation related to memory performance may indicate a compensatory process for a less extensive functional network...
  28. ncbi request reprint Mismatch responses to randomized gradient switching noise as reflected by fMRI and whole-head magnetoencephalography
    Klaus Mathiak
    Department of Neuroradiology, University of Tubingen, Germany
    Hum Brain Mapp 16:190-5. 2002
    ..The presented paradigm provides a robust and feasible tool to study the functional anatomy of early cognitive auditory processing in clinical populations such as schizophrenia...
  29. ncbi request reprint Visualization and quantification of disease progression in multiple system atrophy
    Till Karsten Hauser
    Department of General Neurology, Center of Neurology and Hertie Institute for Clinical Brain Research, University of Tubingen, Tubingen, Germany
    Mov Disord 21:1674-81. 2006
    ....
  30. ncbi request reprint The neural correlates of perceiving one's own movements
    Dirk T Leube
    Department of Psychiatry, University of Tuebingen, Osianderstr 24, 72076 Tuebingen, Germany
    Neuroimage 20:2084-90. 2003
    ..These results might be useful to refine theories about the role of forward mechanisms in the emergence of disorders of the self, such as in schizophrenia...
  31. ncbi request reprint Mismatch negativity responses in schizophrenia: a combined fMRI and whole-head MEG study
    Tilo T J Kircher
    University of Tübingen Department of Psychiatry, Germany
    Am J Psychiatry 161:294-304. 2004
    ..Mismatch negativity response is diminished in patients with schizophrenia. Little is known about the mechanisms of this decreased response, the contribution of the different hemispheres, and its locus of generation...
  32. ncbi request reprint Deceiving oneself about being in control: conscious detection of changes in visuomotor coupling
    Gunther Knoblich
    Max Planck Institute for Psychological Research, Munich, Germany
    J Exp Psychol Hum Percept Perform 30:657-66. 2004
    ..Figural discrepancies increased the detection rates, indicating that additional cues for the what system facilitate conscious change detection...
  33. ncbi request reprint Hippocampal dysfunction during episodic memory encoding in patients with schizophrenia-an fMRI study
    Dirk T Leube
    Schizophr Res 64:83-5. 2003
  34. ncbi request reprint Disorders of agency in schizophrenia correlate with an inability to compensate for the sensory consequences of actions
    Axel Lindner
    Department of Cognitive Neurology, Hertie Institute for Clinical Brain Research, Hoppe Seyler Str 3, D72076 Tübingen, Germany
    Curr Biol 15:1119-24. 2005
    ....
  35. ncbi request reprint The influence of face similarity in the case of the perception of morphed self-face
    Hyo Woon Yoon
    fMRI Laboratory of Brain Science Research Center, Korea Advanced Institute of Science and Technology, Daejon, Republic of Korea
    Int J Neurosci 115:839-49. 2005
    ..The authors interpret this result as being uniquely associated to the facial self-recognition and suggest that this association might be related to the "self effect."..