Stefan Kippenberger

Summary

Affiliation: University of Frankfurt
Country: Germany

Publications

  1. ncbi request reprint Mechanical stretch stimulates protein kinase B/Akt phosphorylation in epidermal cells via angiotensin II type 1 receptor and epidermal growth factor receptor
    Stefan Kippenberger
    Department of Dermatology, University of Frankfurt Medical School, D 60596 FrankfurtMain, Germany
    J Biol Chem 280:3060-7. 2005
  2. doi request reprint Ligand activation of peroxisome proliferator-activated receptor delta suppresses cathepsin B expression in human endothelial cells in a posttranslational manner
    Gabi Reichenbach
    Department of Dermatology, Venereology and Allergology, Frankfurt am Main, Germany
    Exp Dermatol 21:751-7. 2012
  3. doi request reprint Ligation of beta4 integrins activates PKB/Akt and ERK1/2 by distinct pathways-relevance of the keratin filament
    Stefan Kippenberger
    Department of Dermatology and Venerology, University of Frankfurt Medical School, D 60590 Frankfurt Main, Germany
    Biochim Biophys Acta 1803:940-50. 2010
  4. doi request reprint PPARα agonist Wy14643 suppresses cathepsin B in human endothelial cells via transcriptional, post-transcriptional and post-translational mechanisms
    Gabi Reichenbach
    Department of Dermatology, Venereology and Allergology, Johann Wolfgang Goethe University, Frankfurt am Main, Germany
    Angiogenesis 16:223-33. 2013
  5. ncbi request reprint Hypotonic stress induces E-cadherin expression in cultured human keratinocytes
    Stefan Kippenberger
    Department of Dermatology, University of Frankfurt Medical School, D 60590 Frankfurt Main, Germany
    FEBS Lett 579:207-14. 2005
  6. ncbi request reprint Restoration of E-cadherin sensitizes human melanoma cells for apoptosis
    Stefan Kippenberger
    Department of Dermatology, Division of Pneumology, University of Frankfurt Medical School, Frankfurt Main, Germany
    Melanoma Res 16:393-403. 2006
  7. pmc Vascular endothelial growth factor C-induced lymphangiogenesis decreases tumor interstitial fluid pressure and tumor
    Matthias Hofmann
    Department of Dermatology, Venereology and Allergology, Goethe University, Frankfurt Main, Germany
    Transl Oncol 6:398-404. 2013
  8. doi request reprint 'Nosing Around' the human skin: what information is concealed in skin odour?
    Stefan Kippenberger
    Department of Dermatology, Venereology and Allergy, Johann Wolfgang Goethe University, Frankfurt Main, Germany
    Exp Dermatol 21:655-9. 2012
  9. doi request reprint Integration of Langerhans-like cells into a human skin equivalent
    Vesselina Laubach
    Department of Dermatology, Venerology and Allergology, University Hospital, Johann Wolfgang Goethe University, Theodor Stern Kai 7, Frankfurt Main, Germany
    Arch Dermatol Res 303:135-9. 2011
  10. doi request reprint Dimethyl fumarate - only an anti-psoriatic medication?
    Markus Meissner
    Department of Dermatology, Venereology and Allergology, University of Frankfurt, Germany
    J Dtsch Dermatol Ges 10:793-801. 2012

Collaborators

  • Roland Kaufmann
  • Matthias Hofmann
  • Jan Havlicek
  • Jens Gille
  • August Bernd
  • Markus Meissner
  • Gabi Reichenbach
  • Jurgen Bereiter-Hahn
  • Monika Doll
  • Vesselina Laubach
  • Anna Starzinski-Powitz
  • Eva Maria Valesky
  • Igor Hrgovic
  • Nadja Nicole Zöller
  • Diamant Thaci
  • Annette Dorn
  • Jadranka Dujic
  • Yvonne Knies
  • Bonnie F Sloane
  • Nadja Zöller
  • Kerstin Görg
  • Barbara Berlinski
  • Maila Rossberg
  • Martina Spiegel
  • Karsten Mewes
  • Andrea Sättler
  • Maike Schultz
  • Andreas Bock
  • Katja Hardt
  • Joquin Diaz-Alperi
  • Stephanie Hoffmann
  • Ana Ramirez-Bosca
  • Ralf Joachim Ludwig
  • Jaime Miquel

Detail Information

Publications18

  1. ncbi request reprint Mechanical stretch stimulates protein kinase B/Akt phosphorylation in epidermal cells via angiotensin II type 1 receptor and epidermal growth factor receptor
    Stefan Kippenberger
    Department of Dermatology, University of Frankfurt Medical School, D 60596 FrankfurtMain, Germany
    J Biol Chem 280:3060-7. 2005
    ..Evidence is provided that stretch-induced activation of PKB/Akt protects cells against induced apoptosis...
  2. doi request reprint Ligand activation of peroxisome proliferator-activated receptor delta suppresses cathepsin B expression in human endothelial cells in a posttranslational manner
    Gabi Reichenbach
    Department of Dermatology, Venereology and Allergology, Frankfurt am Main, Germany
    Exp Dermatol 21:751-7. 2012
    ..The results bolster other studies demonstrating PPARδ agonists as anti-inflammatory and anticarcinogenic agents and thus might have the potential to help to develop new pharmaceutical drugs...
  3. doi request reprint Ligation of beta4 integrins activates PKB/Akt and ERK1/2 by distinct pathways-relevance of the keratin filament
    Stefan Kippenberger
    Department of Dermatology and Venerology, University of Frankfurt Medical School, D 60590 Frankfurt Main, Germany
    Biochim Biophys Acta 1803:940-50. 2010
    ..Taken together our data define a new model of beta4-dependent PKB/Akt and ERK1/2 activation demonstrating the keratin filament as a structure necessary in signal transmission...
  4. doi request reprint PPARα agonist Wy14643 suppresses cathepsin B in human endothelial cells via transcriptional, post-transcriptional and post-translational mechanisms
    Gabi Reichenbach
    Department of Dermatology, Venereology and Allergology, Johann Wolfgang Goethe University, Frankfurt am Main, Germany
    Angiogenesis 16:223-33. 2013
    ..Overall, our results suggest that the PPARα-dependent anti-angiogenic action of Wy14643 seems to be mediated, in part, by Wy14643-dependent but PPARα-independent regulation of cathepsin B expression...
  5. ncbi request reprint Hypotonic stress induces E-cadherin expression in cultured human keratinocytes
    Stefan Kippenberger
    Department of Dermatology, University of Frankfurt Medical School, D 60590 Frankfurt Main, Germany
    FEBS Lett 579:207-14. 2005
    ..It is likely that induction of E-cadherin contributes to the stabilization between adjacent cells in order to withstand the physical forces induced by hypotonicity...
  6. ncbi request reprint Restoration of E-cadherin sensitizes human melanoma cells for apoptosis
    Stefan Kippenberger
    Department of Dermatology, Division of Pneumology, University of Frankfurt Medical School, Frankfurt Main, Germany
    Melanoma Res 16:393-403. 2006
    ..In conclusion, our findings suggest therapeutic strategies that enable expression of E-cadherin in order to sensitize human melanoma cells towards apoptosis...
  7. pmc Vascular endothelial growth factor C-induced lymphangiogenesis decreases tumor interstitial fluid pressure and tumor
    Matthias Hofmann
    Department of Dermatology, Venereology and Allergology, Goethe University, Frankfurt Main, Germany
    Transl Oncol 6:398-404. 2013
    ..This model represents a novel approach to modulate biomechanical properties of the tumor interstitium enabling a lowering of TIFP in vivo. ..
  8. doi request reprint 'Nosing Around' the human skin: what information is concealed in skin odour?
    Stefan Kippenberger
    Department of Dermatology, Venereology and Allergy, Johann Wolfgang Goethe University, Frankfurt Main, Germany
    Exp Dermatol 21:655-9. 2012
    ..Finally, it is discussed if human skin odour has the quality to act as pheromone transmitting information between individuals in terms of major histocompatibility complex type or reproductive status...
  9. doi request reprint Integration of Langerhans-like cells into a human skin equivalent
    Vesselina Laubach
    Department of Dermatology, Venerology and Allergology, University Hospital, Johann Wolfgang Goethe University, Theodor Stern Kai 7, Frankfurt Main, Germany
    Arch Dermatol Res 303:135-9. 2011
    ..These skin models provide a tool to further investigate the interactions between Langerhans-like cells and other skin cells and particularly learn more about the cutaneous immune response...
  10. doi request reprint Dimethyl fumarate - only an anti-psoriatic medication?
    Markus Meissner
    Department of Dermatology, Venereology and Allergology, University of Frankfurt, Germany
    J Dtsch Dermatol Ges 10:793-801. 2012
    ..This valued and well-known drug mainly prescribed by dermatologists is now experiencing a renaissance far beyond dermatologic applications...
  11. doi request reprint AP1-dependent repression of TGFα-mediated MMP9 upregulation by PPARδ agonists in keratinocytes
    Markus Meissner
    Department of Dermatology, Johann Wolfgang Goethe University, Frankfurt am Main, Germany
    Exp Dermatol 20:425-9. 2011
    ..In conclusion, our data provide the first evidence that MMP9 expression induced by TGFα is a valid target of PPARδ ligands in keratinocytes...
  12. ncbi request reprint Mechanical pressure-induced phosphorylation of p38 mitogen-activated protein kinase in epithelial cells via Src and protein kinase C
    Matthias Hofmann
    Department of Dermatology and Venerology, University Hospital, Johann Wolfgang Goethe University, D 60590 Frankfurt Main, Germany
    Biochem Biophys Res Commun 316:673-9. 2004
    ..These findings suggest mechanical pressure as a new type of effector stimulus for the p38 pathway with implications to (patho-) physiological conditions...
  13. ncbi request reprint Low concentrations of curcumin induce growth arrest and apoptosis in skin keratinocytes only in combination with UVA or visible light
    Jadranka Dujic
    Department of Dermatology and Venerology, Medical School, J W Goethe University, Frankfurt Main, Germany
    J Invest Dermatol 127:1992-2000. 2007
    ..In particular, the latter avoids the use of carcinogenic irradiation that is part of regular phototherapy...
  14. ncbi request reprint Long-term lowering of tumour interstitial fluid pressure reduces Ki-67 expression
    Matthias Hofmann
    Department of Dermatology and Venerology, Johann Wolfgang Goethe University, Theodor Stern Kai 7, D 60590 Frankfurt Main, Germany
    J Biomech 40:2324-9. 2007
    ..While a singular puncture had no effect catheterized tumours showed a significant decrease in Ki-67 expression. Our data suggest that long-term lowering of TIFP is required to reduce tumour proliferation...
  15. ncbi request reprint Oligonucleotides suppress IL-8 in skin keratinocytes in vitro and offer anti-inflammatory properties in vivo
    Annette Dorn
    Department of Dermatology and Venerology, J W Goethe University, Frankfurt Main, Germany
    J Invest Dermatol 127:846-54. 2007
    ..This effect seems to be independent from Toll-like receptor 9...
  16. ncbi request reprint Mechanical stretch induces clustering of beta1-integrins and facilitates adhesion
    Yvonne Knies
    Department of Dermatology and Venerology, University Hospital, Johann Wolfgang Goethe University, Frankfurt Main, Germany
    Exp Dermatol 15:347-55. 2006
    ..In summary, these results show a functional cooperation of beta1-integrins and EGFR in the adhesion complex supporting the transmission of stretch-induced signals...
  17. ncbi request reprint Ligation of the beta4 integrin triggers adhesion behavior of human keratinocytes by an "inside-out" mechanism
    Stefan Kippenberger
    Zentrum der Dermatologie und Venerologie, Klinikum der J W Goethe Universitat, Theodor Stern Kai 7, 60590 Frankfurt Main, Germany
    J Invest Dermatol 123:444-51. 2004
    ..Hence, these findings provide further insight into the conversion processes during carcinogenesis and show the beta(4) integrin to be a key regulator of cellular adhesion...
  18. doi request reprint Evaluation of beneficial and adverse effects of glucocorticoids on a newly developed full-thickness skin model
    Nadja Nicole Zöller
    Department of Dermatology and Venerology, J W Goethe University, Medical School, Theodor Stern Kai 7, 60590 Frankfurt Main, Germany
    Toxicol In Vitro 22:747-59. 2008
    ..The present study demonstrates the versatility of this FTSM in the validation of effectiveness and safety of GCs...