Research Topics
Species | Susanne KarchSummaryAffiliation: University of Munich Country: Germany Publications
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Publications
Increased γ oscillations during voluntary selection processes in adult patients with attention deficit/hyperactivity disorderSusanne Karch
Department of Psychiatry and Psychotherapy, Ludwig Maximilians University Munich, Nussbaumstrasse 7, 80336 Munich, Germany
J Psychiatr Res 46:1515-23. 2012..In addition, the error rate was increased in patients. Given that gamma-band responses have been related to GABAergic and glutamatergic responses these results may indicate accordant dysfunction in patients with ADHD...
Functional magnetic resonance imaging and treatment strategies in schizophreniaSusanne Karch
Department of Psychiatry and Psychotherapy, Ludwig Maximilians University Munich, Nussbaumstraße 7, D 80336 Munich, Germany
Curr Pharm Biotechnol 13:1622-9. 2012..The influence of functional differences on the differential effect of typical and atypical antipsychotics on cognitive functions will be discussed...
Inefficient neural activity in patients with schizophrenia and nonpsychotic relatives of schizophrenic patients: evidence from a working memory taskSusanne Karch
Department of Psychiatry and Psychotherapy, Ludwig Maximilians University, Nussbaumstrasse 7, D 80336 Munich, Germany
J Psychiatr Res 43:1185-94. 2009..In addition, compensatory strategies were demonstrated. These findings suggest that the genetic risk for schizophrenia is accompanied by neural inefficiency which is associated with cognitive deficits, especially in difficult tasks...
Neural correlates (ERP/fMRI) of voluntary selection in adult ADHD patientsSusanne Karch
Department of Psychiatry and Psychotherapy, Ludwig Maximilians University Munich, Nussbaumstrasse 7, 80336, Munich, Germany
Eur Arch Psychiatry Clin Neurosci 260:427-40. 2010..These results may indicate that selection processes are related to dysfunctions, predominantly in frontal brain regions in ADHD patients...
Separating distinct aspects of the voluntary selection between response alternatives: N2- and P3-related BOLD responsesSusanne Karch
Department of Psychiatry and Psychotherapy, Ludwig Maximilians University Munich, Nussbaumstr 7, D 80336 Munich, Germany
Neuroimage 51:356-64. 2010..In addition, at least some frontal brain regions seemed to be involved at an earlier stage than temporo-parietal regions, probably indicating a top-down process...
Influence of trait anxiety on inhibitory control in alcohol-dependent patients: simultaneous acquisition of ERPs and BOLD responsesSusanne Karch
Department of Psychiatry, Ludwig Maximilians University of Munich, Nussbaumstrasse 7, D 80336 Munich, Germany
J Psychiatr Res 42:734-45. 2008..This may indicate that comorbid psychiatric symptoms need to be considered when assessing brain responses in alcohol-dependent patients...
Influence of anxiety on electrophysiological correlates of response inhibition capacities in alcoholismSusanne Karch
Dept of Psychiatry, Ludwig Maximilians University, Munich, Germany
Clin EEG Neurosci 38:89-95. 2007..The results emphasize the importance of monitoring trait anxiety in studies regarding cognitive functions in subjects with alcohol use disorder...
The free choice whether or not to respond after stimulus presentationSusanne Karch
Department of Psychiatry and Psychotherapy, Ludwig Maximilians University Munich, Munich, Germany
Hum Brain Mapp 30:2971-85. 2009..g. somatosensory cortical areas). Altogether, decision processes were shown to be relatively independent of the kind of response chosen...
Auditory cortex and anterior cingulate cortex sources of the early evoked gamma-band response: relationship to task difficulty and mental effortChristoph Mulert
Department of Psychiatry, LMU, Nussbaumstrasse 7, D 80336 Munich, Germany
Neuropsychologia 45:2294-306. 2007..These findings are in line with a top-down influence of dACC-activity to the auditory association area 22 during the early evoked GBR...
Alterations of the early auditory evoked gamma-band response in first-degree relatives of patients with schizophrenia: hints to a new intermediate phenotypeGregor Leicht
University Medical Center Hamburg Eppendorf, Department of Psychiatry and Psychotherapy, Psychiatry Neuroimaging Branch PNB, Hamburg, Germany
J Psychiatr Res 45:699-705. 2011..marker as an intermediate phenotype for schizophrenia, this is the main question of our investigation: Is the early eGBR decreased regarding evoked power and phase locking in first-degree relatives of patients with schizophrenia?..
Reduced early auditory evoked gamma-band response in patients with schizophreniaGregor Leicht
Department of Psychiatry and Psychotherapy, Ludwig Maximilians University, 7D 80336 Munich, Germany
Biol Psychiatry 67:224-31. 2010..power and phase-locking in schizophrenic patients?; and 2) Is this possible decrease a result of reduced activity in the auditory cortex and/or the anterior cingulate cortex (ACC), which were identified as sources of the GBR previously?..
Single-trial coupling of EEG and fMRI reveals the involvement of early anterior cingulate cortex activation in effortful decision makingChristoph Mulert
Department of Psychiatry, LMU, Nussbaumstrasse 7, 80336 Munich, Germany
Neuroimage 42:158-68. 2008..4). These findings suggest a role of early ACC activation in effort-related decision making and provide a direct link between the N1 component and its corresponding BOLD signal...
Attention to emotion: auditory-evoked potentials in an emotional choice reaction task and personality traits as assessed by the NEO FFIVerena Mittermeier
Department of Psychiatry and Psychotherapy, LMU, Munich, Germany
Eur Arch Psychiatry Clin Neurosci 261:111-20. 2011..Interestingly, subjects with high scores in the personality trait extraversion showed significantly higher EPN amplitudes for emotional paradigms (syllables and words) than introverted subjects...
Rostral anterior cingulate cortex activity in the theta band predicts response to antidepressive medicationChristoph Mulert
Department of Psychiatry, Ludwig Maximilians University, Munich, Germany
Clin EEG Neurosci 38:78-81. 2007..In addition to major differences between responders and nonresponders in the rostral ACC, we have identified a nearby region in the midline orbito-frontal region...
Loudness dependence of auditory evoked potentials in patients with borderline personality disorder--impact of psychopathologyNadine Schaaff
Department of Psychiatry, Ludwig Maximilian University of Munich, Germany
Psychiatry Res 199:181-7. 2012..The significant clinical correlations suggest monoaminergic modulations of psychopathology on the symptom level...
Impact of loudness dependency of auditory evoked potentials on the panic response to CCK-4Daniela Eser
Department of Psychiatry and Psychotherapy, Ludwig Maximilian University, Nussbaumstrasse 7, 80336 Munich, Germany
J Psychiatr Res 43:393-400. 2009..The analysis of the loudness dependency of the auditory evoked potentials (LDAEP) is a valid non-invasive indicator of central serotonergic activity...
Sound level dependence of the primary auditory cortex: Simultaneous measurement with 61-channel EEG and fMRIChristoph Mulert
Department of Psychiatry, LMU, Munich, Germany
Neuroimage 28:49-58. 2005..In addition, the correspondence of the ERP-based data and the fMRI results further supports the validity of the ERP localization approach...
A Ser9Gly polymorphism in the dopamine D3 receptor gene (DRD3) and event-related P300 potentialsChristoph Mulert
Department of Psychiatry, University of Munich, LMU, Munich, Germany
Neuropsychopharmacology 31:1335-44. 2006..Further studies should address the direct role of the DRD3 Ser9Gly polymorphism in attenuated P300 amplitudes in psychiatric disorders like schizophrenia or alcoholism...
Prediction of clinical response to antidepressants in patients with depression: neurophysiology in clinical practiceOliver Pogarell
Department of Psychiatry, Ludwig Maximilians University, Munich, Germany
Clin EEG Neurosci 38:74-7. 2007..This review focuses on recent studies providing evidence for the validity of LD as an indirect serotonergic marker and highlights data on the clinical application in terms of prediction of treatment response in patients with depression...
Avoiding the ballistocardiogram (BCG) artifact of EEG data acquired simultaneously with fMRI by pulse-triggered presentation of stimuliMatthias Ertl
Department of Psychiatry, LMU, Munich, Germany
J Neurosci Methods 186:231-41. 2010..In combination with an averaged artifact subtraction method signal distortion was reduced at best by 47%...
Prediction of treatment response in major depression: integration of conceptsChristoph Mulert
Department of Psychiatry, LMU, Munich, Germany
J Affect Disord 98:215-25. 2007..Here, a high LDAEP is supposed to reflect low central serotonergic activity. We present the first study comparing both approaches in the same group of patients...
Functional neuroanatomy of CCK-4-induced panic attacks in healthy volunteersDaniela Eser
Department of Psychiatry and Psychotherapy, Ludwig Maximilians University, Munich, Germany
Hum Brain Mapp 30:511-22. 2009..In conclusion, while overall brain activation patterns are not related to the subjective anxiety response to CCK-4, amygdala activation may be involved in the subjective perception of CCK-4-induced fear...
Dopaminergic mechanisms of target detection - P300 event related potential and striatal dopamineOliver Pogarell
Department of Psychiatry, Ludwig Maximilian University of Munich, Germany
Psychiatry Res 194:212-8. 2011..This association might be of relevance for the interpretation of P300 studies in psychiatric disorders...
A controlled single case study with repeated fMRI measurements during the treatment of a patient with obsessive-compulsive disorder: testing the nonlinear dynamics approach to psychotherapyGünter Schiepek
Department of Psychology, Ludwig Maximilians University of Munich, Munich, Germany
World J Biol Psychiatry 10:658-68. 2009....
Theta burst stimulation of the prefrontal cortex: safety and impact on cognition, mood, and resting electroencephalogramNicola Grossheinrich
Department of Psychiatry and Psychotherapy, Ludwig Maximilian University, Munich, Germany
Biol Psychiatry 65:778-84. 2009..Thus, the present study explores whether TBS is safe particularly in terms of effects on cognition, mood, and electroencephalogram (EEG) measures in healthy subjects...
EEG-vigilance and BOLD effect during simultaneous EEG/fMRI measurementSebastian Olbrich
Department of Psychiatry, University of Leipzig, Semmelweisstrasse 10, D 04103 Leipzig, Germany
Neuroimage 45:319-32. 2009..For cognitive fMRI-research it therefore seems important to pay attention to vigilance switches in order to separate vigilance associated BOLD signal changes from those specifically related to cognition...
Benzodiazepines counteract rostral anterior cingulate cortex activation induced by cholecystokinin-tetrapeptide in humansGregor Leicht
Psychiatry Neuroimaging Branch, University Medical Center Hamburg Eppendorf, Department of Psychiatry and Psychotherapy, Psychiatry Neuroimiaging Branch, Hamburg, Germany
Biol Psychiatry 73:337-44. 2013..However, it is not fully understood which brain regions within anxiety-related brain circuits are really responsible for their anxiolytic effects and how these regions interact...
Brain mechanisms associated with background monitoring of the environment for potentially significant sensory eventsOliver Gruber
Department of Psychiatry, Georg August University, Goettingen, Germany
Brain Cogn 69:559-64. 2009..This fronto-parietal network may thus play an important role in adaptive responding to potentially significant events outside the current focus of attention...
Electroconvulsive therapy and corpus callosum aplasia: a case reportUlrich Palm
Department of Psychiatry and Psychotherapy, Ludwig Maximilian University of Munich, Munich, Germany
J ECT 27:e17-20. 2011..Electroconvulsive therapy turned out to be a powerful tool for treating catatonic syndromes in patients with mental retardation and should be considered as a potent treatment option in otherwise therapy-resistant cases...
