- Genotypic tropism testing by massively parallel sequencing: qualitative and quantitative analysisMartin Daumer
Institute of Immunology and Genetics, Pfaffplatz 10, 67655 Kaiserslautern, Germany
BMC Med Inform Decis Mak 11:30. 2011..Massively parallel sequencing (MPS) detects single clones thereby being much more sensitive. Using this technology we wanted to improve genotypic prediction of coreceptor usage...
- The L76V mutation in HIV-1 protease is potentially associated with hypersusceptibility to protease inhibitors Atazanavir and Saquinavir: is there a clinical advantage?Frank Wiesmann
PZB Aachen, HIV and Hepatitis Research Group, Blondelstr, 52062 Aachen, Germany
AIDS Res Ther 8:7. 2011..Beside an enhancement of resistance, L76V is also discussed to confer hypersusceptibility to the drugs Atazanavir and Saquinavir which might enable new treatment strategies by trying to take advantage of particular mutations...