Research Topics
Genomes and GenesSpecies | S JonasSummaryAffiliation: University of Leipzig Country: Germany Publications
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Detail Information
Publications
A patient presenting with abdominal pain to the general practitioner: a case reportThomas Frese
Department of Primary Care of the Leipzig Medical School, Philipp Rosenthal Strasse 55, 04103 Leipzig, Germany
Cases J 2:9297. 2009..Right-sided upper abdominal pain is a common cause of presentation to general practitioners...
Radical surgery for hilar cholangiocarcinomaS Jonas
Department of General, Visceral and Transplantation Surgery, Charite Campus Virchow Klinikum, Humboldt University, Augustenburger Platz 1, 13353 Berlin, Germany
Eur J Surg Oncol 34:263-71. 2008..A substantial drop out rate from this neoadjuvant regimen due to tumor progression or treatment related complications is still a problem...
Extended resections of liver metastases from colorectal cancerS Jonas
Department of General, Visceral and Transplantation Surgery, Charite Campus Virchow Klinikum, University Medicine, Augustenburger Platz 1, 13353, Berlin, Germany
World J Surg 31:511-21. 2007..Indications for resection of liver metastases from colorectal cancer and surgical strategies are still under debate...
Adult living donor liver transplantation: living donation of the right liver lobeJ Mittler
Department of General, Visceral and Transplant Surgery, Charite Campus Virchow Klinikum, Universitatsmedizin Berlin, Augustenburger Platz 1, 13353 Berlin, Germany
Langenbecks Arch Surg 392:657-62. 2007..In European and North American countries, LDLT for adult recipients is mainly performed with right lobe grafts. Indications, when compared to deceased donor liver transplantation, are controversial...
Liver transplantation for treatment of intrahepatic Osler's disease: first experiencesR Pfitzmann
Department of General, Visceral, and Transplantation Surgery, , Campus Virchow-Klinikum, Humboldt-University Berlin, Augustenburger Platz 1, 13353 Berlin, Germany
Transplantation 72:237-41. 2001..Our therapeutic regimen of early liver transplantation in the case of intrahepatic Osler's disease in four patients has promising results...
Liver resection for metastases from renal cell carcinomaArmin Thelen
Departmant of General, Visceral and Transplantation Surgery, Campus Virchow Klinikum, Charite Universitaetsmedizin Berlin, Berlin, Germany
World J Surg 31:802-7. 2007..This study was conducted to evaluate the safety and efficacy of liver resection in patients with hepatic metastases from renal cell carcinoma and to identify selection criteria for patients suitable for resection...
Liver resection for metastatic gastric cancerA Thelen
Departmant of General, Visceral and Transplantation Surgery, Campus Virchow Klinikum, Charite Universitaetsmedizin Berlin, Berlin, Germany
Eur J Surg Oncol 34:1328-34. 2008..This study was conducted to evaluate the safety and effectiveness of liver resection in these conditions and to identify criteria for the selection of suitable patients...
Changes in serum levels of growth factors in healthy individuals after living related liver donationE A Efimova
Department of General, Visceral and Transplantation Surgery, Charite, Campus Virchow Clinic, University Medicine, Berlin, Germany
Transplant Proc 37:1074-5. 2005....
Repeat liver resection for recurrent liver metastases from colorectal cancerA Thelen
Departmant of General, Visceral and Transplantation Surgery, Campus Virchow Klinikum, Charite Universitaetsmedizin Berlin, Augustenburger Platz 1, 13353 Berlin, Germany
Eur J Surg Oncol 33:324-8. 2007..This study was conducted to clarify safety and effectiveness of this treatment and to identify prognostic factors of a favourable outcome after repeat hepatectomy...
Liver transplantation for hepatocellular carcinoma in cirrhosis: prognostic parametersC Benckert
Department of General, Visceral- and Transplantation Surgery, Charit, Campus Virchow Klinikum, Universitatsmedizin Berlin, Berlin, Germany
Transplant Proc 37:1693-4. 2005..Exeptions from the morphometric rules may be justified for patients with HCC in cirrhosis who show well or moderately differentiated tumors with vascular invasion...
Vascular invasion and histopathologic grading determine outcome after liver transplantation for hepatocellular carcinoma in cirrhosisS Jonas
Department of General Surgery, Humboldt University, Berlin, Germany
Hepatology 33:1080-6. 2001..Tumor diameter and number of nodules in correlation with the histopathologic grading were predictive of a vascular invasion only in HCC larger than 5 cm...
Liver transplantation in patients with advanced Budd-Chiari syndromeF Ulrich
Department of General, Visceral and Transplantation Surgery, Charite, Virchow-Clinic, Humboldt-University, Berlin, Germany
Transplant Proc 34:2278. 2002
Liver transplantation for recurrent hepatocellular carcinoma in EuropeS Jonas
Department of General, Visceral and Transplantation Surgery, , Humboldt University, Augustenburger Platz 1, 13353 Berlin, Germany
J Hepatobiliary Pancreat Surg 8:422-6. 2001..Adult living donor liver transplantation is one way to overcome graft shortage. Other strategies, for example, salvage transplantation, are presented...
Primary immunosuppression with tacrolimus after liver transplantation: 12-years follow-upS Jonas
Department of General, Visceral and Transplantation Surgery, Charite Virchow Klinikum, University Medicine Berlin, Augustenburger Platz 1, 13353 Berlin, Germany
Int Immunopharmacol 5:125-8. 2005..An increased number of de novo malignancies in the ciclosporin-based group may be attributable to the use of ATG as induction therapy...
Living related liver transplantation: preoperative magnetic resonance imaging for assessment of hepatic vasculature of donor candidatesF Streitparth
Department of Radiology, Charite Medical University Center, Campus Virchow Clinic, Augustenburger Platz 1, 13353 Berlin, Germany
Acta Radiol 48:20-6. 2007..To evaluate the accuracy of magnetic resonance angiography (MRA) for preoperative assessment of hepatic vascular anatomy in liver donors before living related liver transplantation...
Therapy of Caroli's disease by orthotopic liver transplantationF Ulrich
Department of General, Visceral and Transplantation Surgery, Charit, Virchow-Clinic, Humboldt-University, Berlin, Germany
Transplant Proc 34:2279-80. 2002
Surgical treatment of a leiomyosarcoma of the inferior vena cava involving the hepatic and renal veins confluences: technical aspectsA Spinelli
Department of General, Visceral and Transplantation Surgery, , Campus Virchow Klinikum, Augustenburger Platz 1, 13353 Berlin, Germany
Eur J Surg Oncol 34:831-5. 2008
First results from a prospective randomized trial comparing steroid-free induction therapy with tacrolimus and MMF versus tacrolimus and steroids in patients after liver transplantation for HCVJ M Langrehr
Department of Surgery, Charit, Virchow-Klinikum, Humboldt University, Augustenburger Platz 1, 13353 Berlin, Germany
Transplant Proc 34:1565-6. 2002
Diabetes mellitus is no independent risk factor for perioperative mortality following hepatic resectionO Guckelberger
Charite Campus Virchow Klinikum, Department of General, Visceral and Transplantation Surgery, Berlin, Germany
Exp Clin Endocrinol Diabetes 114:257-61. 2006....
Effects of human hepatocyte growth factor on the proliferation of human hepatocytes and hepatocellular carcinoma cell linesEkaterina A Efimova
Department of General, Visceral, and Transplantation Surgery, Charite, Campus Virchow Klinikum, Universitatsmedizin Berlin, Berlin, Germany
Eur Surg Res 36:300-7. 2004..The aim of this study was to clarify the role of HGF in the regeneration of human hepatocyte and the growth of residual hepatocellular carcinoma cells after liver resection...
Combination prophylaxis with Hepatitis B immunoglobulin and lamivudine after liver transplantation minimizes HBV recurrence rates unless evolution of pretransplant lamivudine resistanceD Seehofer
Department of General, Visceral and Transplant Surgery, Charite Campus Virchow, Humboldt University of Berlin, Germany
Z Gastroenterol 40:795-9. 2002..Due to viral escape mutations recurrence still occurs, but recently a combination prophylaxis with hepatitis B immunoglobuline plus lamivudine is evaluated in transplant centers in terms of a further reduction of recurrence rates...
Transabdominal ligation of the thoracic duct as treatment of choice for postoperative chylothorax after esophagectomyG Schumacher
Department of General, Visceral, and Transplantation Surgery, Humboldt University, Charite Campus Virchow Klinikum, Berlin, Germany
Dis Esophagus 20:19-23. 2007..Discharge from hospital, after ligation of the thoracic duct, was possible after a median time of 18 days (11-52). Ligation of the thoracic duct via relaparotomy appeared to be a simple and safe method to treat postoperative chylothorax...
[Liability of surgeons with respect to injuries to the bile duct during laparoscopic cholecystectomy : Analyses of malpractice litigations in the years 1996-2009]P T Fellmer
Klinik für Visceral, Transplantations, Thorax und Gefäßchirurgie, Universitätsklinik Leipzig, Deutschland
Chirurg 82:68-73. 2011..Injuries to the bile duct during laparoscopic cholecystectomy are often a cause of malpractice litigations...
Cyclosporine-based quadruple induction therapy versus tacrolimus-based dual immunosuppression after liver transplantation: ten-year follow-upS Jonas
Department of General, Visceral and Transplantation Surgery, , Humboldt University Berlin, Augustenburger Platz 1, 13353 Berlin, Germany
Transplant Proc 34:1504-6. 2002
[Surgical therapy of liver hilus tumors]S Jonas
, Viszeral- und Transplantationschirurgie, , Campus Virchow-Klinikum,
Chirurg 72:775-83. 2001..So far, a putative alteration of tumor cell kinetics due to posttransplant immunosuppressive treatment results in an increased rate of implantation metastases...
[Resection and reconstruction of the retrohepatic vena cava in combination with liver resections]U Settmacher
Klinik fUr Allgemein, Viszeral und Transplantationschirurgie, Campus Virchow Klinikum, Charite, Humboldt Universitat zu Berlin
Zentralbl Chir 130:104-8. 2005..We were able to achieve a long-term survival for surgically treated patients even in cases with advanced tumor stages...
[Acute liver failure--surgical approach]S Jonas
Klinik fUr Allgemein, Viszeral und Transplantationschirurgie, Charite Campus Virchow Klinikum, Universitatsmedizin Berlin
Praxis (Bern 1994) 95:1878-80. 2006..The most important prognostic parameters are the severity of multi organ failures and the degree of encephalopathy prior to transplantation. However, long-term survival thereafter is mostly excellent...
[Resection or ablation in hepatocellular carcinoma: pro resection]C Benckert
, Transplantations, ,
Dtsch Med Wochenschr 133:1579. 2008
[Liver transplantation in hepatocellular carcinoma: new developments]P Neuhaus
, Viszeral- und Transplantations-chirurgie, ,
Schweiz Rundsch Med Prax 91:1396-400. 2002..In multivariate analyses, vascular invasion and histopathological grading were significant risk factors for patient survival. Histopathological grading was also identified as most important risk factor for vascular invasion...
Review article: liver transplantation for hepatocellular carcinomaT Steinmuller
Department of Visceral and Transplantation Surgery, Charite, Campus Virchow Klinikum, Berlin, Germany
Aliment Pharmacol Ther 17:138-44. 2003..Other selection criteria are under investigation. Studies on multimodal therapy are also underway but have not yet demonstrated a clear benefit...
Brain death activates donor organs and is associated with a worse I/R injury after liver transplantationS Weiss
Department of Surgery, Charite, Campus Virchow Clinic, Universitatsmedizin Berlin, Germany
Am J Transplant 7:1584-93. 2007..Based on our clinical data, we demonstrate that brain death and the events that precede it are associated with a significant upregulation of inflammatory cytokines and lead to a worse ischemia/reperfusion injury after transplantation...
Significant reduction of proinflammatory cytokines by treatment of the brain-dead donorO Kuecuek
Deutsche Stiftung Organtransplantation, DSO Berlin-Brandenburg, Berlin, Germany
Transplant Proc 37:387-8. 2005..Our data suggest a beneficial effect of anti-inflammatory treatment of brain-dead organ donors...
Effect of anti-CD 20 antibody rituximab in patients with post-transplant lymphoproliferative disorder (PTLD)S H K Oertel
University Medicine of Berlin, Charite Campus Virchow Clinic, Department of Internal Medicine, Berlin, Germany
Am J Transplant 5:2901-6. 2005..Two patients relapsed, at intervals 3 and 5 months after obtaining complete remission. Rituximab proved to be well tolerated and effective in the treatment of PTLD...
[Transplantation and liver resection for hepatocellular carcinoma in cirrhosis]C Benckert
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Dtsch Med Wochenschr 130:S245-7. 2005
Magnetic resonance imaging including magnetic resonance cholangiopancreatography for tumor localization and therapy planning in malignant hilar obstructionsE L Hanninen
Department of Radiology, Charite Medical University Center, Campus Virchow Clinic, Berlin, Germany
Acta Radiol 46:462-70. 2005..To assess image quality and overall accuracy of magnetic resonance imaging (MRI), including two magnetic cholangiopancreatography (MRCP) techniques, for the diagnostics and preoperative work-up of malignant hilar obstructions...
