G Janka

Summary

Affiliation: University of Hamburg
Country: Germany

Publications

  1. ncbi request reprint Modern management of children with haemophagocytic lymphohistiocytosis
    Gritta E Janka
    Department of Haematology and Oncology, Children s Hospital, University of Hamburg, Hamburg, Germany
    Br J Haematol 124:4-14. 2004
  2. pmc Recent advances in the diagnosis and treatment of hemophagocytic lymphohistiocytosis
    Sebastian Fn Bode
    Centre of Chronic Immunodeficiency, University Medical Center Freiburg, D 79106 Freiburg, Germany
    Arthritis Res Ther 14:213. 2012
  3. doi request reprint Familial and acquired hemophagocytic lymphohistiocytosis
    G E Janka
    Department of Hematology and Oncology, Children s University Hospital, Hamburg, Germany
    Annu Rev Med 63:233-46. 2012
  4. doi request reprint Hemophagocytic lymphohistiocytosis: when the immune system runs amok
    G Janka
    Pediatric Hematology and Oncology, University Medical Center Hamburg Eppendorf, Hamburg, Germany
    Klin Padiatr 221:278-85. 2009
  5. ncbi request reprint [In vitro drug resistance as independent prognostic factor in the study COALL-O5-92 Treatment of childhood acute lymphoblastic leukemia; two-tiered classification of treatments based on accepted risk criteria and drug sensitivity profiles in study COALL-0
    G E Janka-Schaub
    Abt für Pädiatrische Hämatologie und Onkologie, Universitätskinderklinik Hamburg
    Klin Padiatr 211:233-8. 1999
  6. ncbi request reprint Hemophagocytic syndromes
    Gritta E Janka
    Department of Hematology and Oncology, Children s Hospital, University of Hamburg, Martinistrasse 52, 20246 Hamburg, Germany
    Blood Rev 21:245-53. 2007
  7. ncbi request reprint Familial and acquired hemophagocytic lymphohistiocytosis
    Gritta E Janka
    Department of Hematology and Oncology, Children s Hospital, University of Hamburg, Hamburg, Germany
    Eur J Pediatr 166:95-109. 2007
  8. ncbi request reprint [Minimal residual disease analysis in acute lymphoblastic leukemia of childhood within the framework of COALL Study: results of an induction therapy without asparaginase]
    U zur Stadt
    Abt für Pädiatrische Hämatologie und Onkologie, Universitätskinderklinik Eppendorf, Hamburg
    Klin Padiatr 212:169-73. 2000
  9. ncbi request reprint From neonates to adolescents--the diagnostic significance of pitted erythrocytes in hyposplenic and asplenic children
    K Lehmberg
    Department of Paediatric Haematology and Oncology, Children s Hospital, University of Hamburg, Hamburg
    Klin Padiatr 219:339-42. 2007
  10. doi request reprint Distribution of cardiac iron measured by magnetic resonance imaging (MRI)-R*2
    Jin Yamamura
    University Medical Center Hamburg Eppendorf, Hamburg, Germany
    J Magn Reson Imaging 32:1104-9. 2010

Collaborators

  • R Pieters
  • K Lehmberg
  • Sebastian Fn Bode
  • Jin Yamamura
  • Ulrike B Graubner
  • Stephan Ehl
  • Udo Zur Stadt
  • Thomas Vraetz
  • Andrea Maul-Pavicic
  • Roland Fischer
  • U zur Stadt
  • Gerhard Adam
  • Regine Grosse
  • Joachim Graessner
  • D O Harms
  • Reinhard Kolb
  • G E Janka-Schaub
  • Rüdiger Wessalowski
  • Simone Porzig
  • Gabriele Escherich
  • Norbert Jorch
  • H Kabisch
  • P Gutjahr
  • N Jorch
  • S Schluter
  • W Nurnberger
  • H J Spaar
  • M Schrappe
  • S Völpel
  • M L den Boer
  • A J Veerman

Detail Information

Publications11

  1. ncbi request reprint Modern management of children with haemophagocytic lymphohistiocytosis
    Gritta E Janka
    Department of Haematology and Oncology, Children s Hospital, University of Hamburg, Hamburg, Germany
    Br J Haematol 124:4-14. 2004
  2. pmc Recent advances in the diagnosis and treatment of hemophagocytic lymphohistiocytosis
    Sebastian Fn Bode
    Centre of Chronic Immunodeficiency, University Medical Center Freiburg, D 79106 Freiburg, Germany
    Arthritis Res Ther 14:213. 2012
    ..Current research aims at a better understanding of disease pathogenesis and evaluation of more targeted approaches to therapy, including anti-cytokine antibodies and gene therapy...
  3. doi request reprint Familial and acquired hemophagocytic lymphohistiocytosis
    G E Janka
    Department of Hematology and Oncology, Children s University Hospital, Hamburg, Germany
    Annu Rev Med 63:233-46. 2012
    ..Treatment of HLH includes immune-suppressive and immune-modulatory agents, cytostatic drugs, and biological response modifiers. For patients with FHL, stem cell transplantation is indicated and can be curative...
  4. doi request reprint Hemophagocytic lymphohistiocytosis: when the immune system runs amok
    G Janka
    Pediatric Hematology and Oncology, University Medical Center Hamburg Eppendorf, Hamburg, Germany
    Klin Padiatr 221:278-85. 2009
    ..Suppression of the severe hyperinflammation can be achieved with immunosuppressive and immunomodulatory agents and cytostatic drugs. Patients with genetic HLH have to undergo stem cell transplantation for cure...
  5. ncbi request reprint [In vitro drug resistance as independent prognostic factor in the study COALL-O5-92 Treatment of childhood acute lymphoblastic leukemia; two-tiered classification of treatments based on accepted risk criteria and drug sensitivity profiles in study COALL-0
    G E Janka-Schaub
    Abt für Pädiatrische Hämatologie und Onkologie, Universitätskinderklinik Hamburg
    Klin Padiatr 211:233-8. 1999
    ..Additional prognostic criteria are therefore urgently needed. In a retrospective Dutch study in childhood ALL drug sensitivity testing with the MTT assay was identified as a new highly significant prognostic factor...
  6. ncbi request reprint Hemophagocytic syndromes
    Gritta E Janka
    Department of Hematology and Oncology, Children s Hospital, University of Hamburg, Martinistrasse 52, 20246 Hamburg, Germany
    Blood Rev 21:245-53. 2007
    ..Awareness of the clinical symptoms and of the diagnostic criteria of HLH is important to start life-saving therapy with immunosuppressive/immunomodulatory agents in time...
  7. ncbi request reprint Familial and acquired hemophagocytic lymphohistiocytosis
    Gritta E Janka
    Department of Hematology and Oncology, Children s Hospital, University of Hamburg, Hamburg, Germany
    Eur J Pediatr 166:95-109. 2007
    ..In conclusion, awareness of the clinical symptoms and of the diagnostic criteria of HLH is crucial in order not to overlook HLH and to start life-saving therapy in time...
  8. ncbi request reprint [Minimal residual disease analysis in acute lymphoblastic leukemia of childhood within the framework of COALL Study: results of an induction therapy without asparaginase]
    U zur Stadt
    Abt für Pädiatrische Hämatologie und Onkologie, Universitätskinderklinik Eppendorf, Hamburg
    Klin Padiatr 212:169-73. 2000
    ..At the end of induction therapy, bone marrow was obtained for cytomorphologic and molecular analysis...
  9. ncbi request reprint From neonates to adolescents--the diagnostic significance of pitted erythrocytes in hyposplenic and asplenic children
    K Lehmberg
    Department of Paediatric Haematology and Oncology, Children s Hospital, University of Hamburg, Hamburg
    Klin Padiatr 219:339-42. 2007
    ..A simple method with reliable reference values is required to determine a patient's splenic function and thereby assess the risk of systemic infection...
  10. doi request reprint Distribution of cardiac iron measured by magnetic resonance imaging (MRI)-R*2
    Jin Yamamura
    University Medical Center Hamburg Eppendorf, Hamburg, Germany
    J Magn Reson Imaging 32:1104-9. 2010
    ..To assess regional iron distribution by magnetic resonance imaging (MRI)-R(2)* within the heart of patients with β-thalassemia major (TM) and other iron overload diseases...
  11. ncbi request reprint Impact of reduction of therapy on infectious complications in childhood acute lymphoblastic leukemia
    Ulrike B Graubner
    University Children s Hospital, Department of Hematology and Oncology, Munich, Germany
    Pediatr Blood Cancer 50:259-63. 2008
    ..Infections are a major cause of morbidity and mortality in childhood acute lymphoblastic leukemia (ALL) and only limited information is available on infectious complications...