Research Topics
| Gerhard JakseSummaryAffiliation: University Hospital Country: Germany Publications
| Collaborators
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Detail Information
Publications
Impact of age and comorbidities on health-related quality of life for patients with prostate cancer: evaluation before a curative treatmentMichael Pinkawa
Department of Radiation Oncology, RWTH Aachen University, Aachen, Germany
BMC Cancer 9:296. 2009..Furthermore, age-related changes can hardly be discriminated from therapy-related changes. The evaluation of age-and comorbidity-related changes was in focus of this study...
A second-look TUR in T1 transitional cell carcinoma: why?Gerhard Jakse
Urological Clinic, University Clinic of RWTH Aachen, Pauwelsstrasse 30, D 520570 Aachen, Germany
Eur Urol 45:539-46; discussion 546. 2004..Currently, there is no standard appropriate treatment of T1 tumors. However, we strongly recommend that future studies on the conservative treatment of T1 tumors include a second TUR within 2 to 4 weeks after the first one...
Rectourethral fistula following LDR brachytherapyHolger Borchers
Urological Clinic, University Clinic Aachen, RWTH Aachen, Aachen, Germany
Urol Int 82:365-6. 2009..These fistulas cause severe patient morbidity and require interdisciplinary treatment. We report on the occurrence and management of a rectourethral fistula which occurred 4 years after (125)I seed implantation...- Clonal architecture of human prostatic epithelium in benign and malignant conditionsNadine T Gaisa
Institute of Pathology, RWTH, Aachen University, Aachen, Germany
J Pathol 225:172-80. 2011..Importantly, single clonal units comprised both PIN and invasive cancer, supporting PIN as the pre-invasive lesion for prostate cancer... - Prostate-specific antigen kinetics after brachytherapy or external beam radiotherapy and neoadjuvant hormonal therapyMichael Pinkawa
Department of Radiation Oncology, RWTH Aachen University, Aachen, Germany
Urology 69:129-33. 2007..To characterize the kinetics of prostate-specific antigen (PSA) after radiotherapy (RT) and neoadjuvant hormonal therapy (NHT) for localized prostate cancer... - Evaluation of source displacement and dose--volume changes after permanent prostate brachytherapy with stranded seedsMichael Pinkawa
Department of Radiation Oncology, RWTH Aachen University, Aachen, Germany
Radiother Oncol 84:190-6. 2007..The aim of the study was to analyze source displacements and dose-volume changes in the first month after a permanent implant... - Laparoscopic heminephrectomy and resection of ectopic ureter in an adultBernhard Brehmer
Department of Urology, University Hospital, Rheinisch Westfalische Technische Universitat Aachen, Aachen, Germany
Urol Int 79:280-3. 2007..The medical history of the patient, the diagnostic pathway and the laparoscopic treatment as well as the key points in laparoscopic surgery are described... - Endosew: new device for laparoscopic running suturesBernhard Brehmer
Urological Clinic, University Clinic, Rheinisch Westfälische Technical University Aachen, Aachen, Germany
J Endourol 22:307-11. 2008..Therefore, to improve the quality and reduce the time to place running sutures, we developed a new sewing device for laparoscopic use... - Seed displacements after permanent brachytherapy for prostate cancer in dependence on the prostate levelMichael Pinkawa
Department of Radiotherapy, RWTH Aachen, Aachen, Germany
Strahlenther Onkol 184:520-5. 2008..To evaluate seed displacements after permanent prostate brachytherapy considering different prostate levels... - Health-related quality of life after permanent I-125 brachytherapy and conformal external beam radiotherapy for prostate cancer--a matched-pair comparisonMichael Pinkawa
Department of Radiation Oncology, RWTH Aachen University, Aachen, Germany
Radiother Oncol 91:225-31. 2009..The aim of the study was to compare quality of life after permanent I-125 brachytherapy (BT) and external beam radiotherapy (EBRT) for prostate cancer... - Rectal dosimetry following prostate brachytherapy with stranded seeds--comparison of transrectal ultrasound intra-operative planning (day 0) and computed tomography-postplanning (day 1 vs. day 30) with special focus on sources placed close to the rectal wMichael Pinkawa
Department of Radiation Oncology, RWTH Aachen University, Aachen, Germany
Radiother Oncol 91:207-12. 2009..The aim of the study was to compare intra-operative and postplanning at different intervals with special focus on sources placed close to the rectal wall... - Gracilis muscle interposition for the treatment of recto-urethral and rectovaginal fistulas: a retrospective analysis of 35 casesDietmar Ulrich
Department of Plastic Surgery, Hand Surgery, Burn Unit, University Hospital, Medical Faculty of the University of Technology, Pauwelsstrasse 30, D 52074 Aachen, Germany
J Plast Reconstr Aesthet Surg 62:352-6. 2009..Our study was designed to assess the efficacy of the gracilis muscle flap in repairing recto-urethral and rectovaginal fistulas... - Comparing two types of botulinum-A toxin detrusor injections in patients with severe neurogenic detrusor overactivity: a case-control studyJoachim Grosse
University Clinic of Urology, Universitätsklinikum der RWTH Aachen, Aachen, Germany
BJU Int 104:651-6. 2009..Irvine, CA, USA) and examine the possible dose-effect relation for Dysport in those patients, as multifocal detrusor injections with BTX-A are effective for severe neurogenic detrusor overactivity in adults... - Serum proteomic profiling in patients with bladder cancerKristina Schwamborn
Institute of Pathology, Department of Urology, RWTH Aachen University, Aachen, Germany
Eur Urol 56:989-96. 2009..Despite continuing research for accurate bladder cancer biomarkers, the analytes suffer from lack of sensitivity and specificity... - The human urothelium consists of multiple clonal units, each maintained by a stem cellNadine T Gaisa
Institute of Pathology RWTH Aachen University, Aachen, Germany
J Pathol 225:163-71. 2011..The size of the clonal unit attributable to each stem cell was broadly distributed, suggesting replacement of one stem cell clone by another... - Stem cells for regeneration of urological structuresChristoph Becker
Department of Urology, University Hospital and Medical Faculty, RWTH Aachen University, Pauwelsstrasse 30, D 52074 Aachen, Germany
Eur Urol 51:1217-28. 2007..This review focuses on advances in regenerative therapies using stem cells in urology... - Dose-volume impact in high-dose-rate Iridium-192 brachytherapy as a boost to external beam radiotherapy for localized prostate cancer--a phase II studyMichael Pinkawa
Department of Radiation Oncology, RWTH Aachen University, Aachen, Germany
Radiother Oncol 78:41-6. 2006..Evaluation of dose-volume-time-related factors in 64 patients treated with high-dose-rate brachytherapy (HDR-BT) as a boost to external beam radiotherapy (EBRT) for localized prostate cancer... - Health-related quality of life after permanent interstitial brachytherapy for prostate cancer: correlation with postimplant CT scan parametersMichael Pinkawa
Department of Radiotherapy, RWTH Aachen, Pauwelsstrasse 30, 52057 Aachen, Germany
Strahlenther Onkol 182:660-5. 2006..To determine dosimetric risk factors for increased toxicity after permanent interstitial brachytherapy for prostate cancer... - Changes of dose delivery distribution within the first month after permanent interstitial brachytherapy for prostate cancerMichael Pinkawa
Department of Radiotherapy, RWTH Aachen, Aachen, Germany
Strahlenther Onkol 182:525-30. 2006..To evaluate changes of dose distribution for both the prostate and the surrounding tissues after permanent brachytherapy as monotherapy for prostate cancer... - Association of neoadjuvant hormonal therapy with adverse health-related quality of life after permanent iodine-125 brachytherapy for localized prostate cancerMichael Pinkawa
Department of Radiation Oncology, RWTH Aachen University, Aachen, Germany
Urology 68:104-9. 2006..To characterize the influence of neoadjuvant hormonal therapy (NHT) on health-related quality of life after permanent iodine-125 brachytherapy (BT) for prostate cancer... - Permanent 125I-seed brachytherapy or radical prostatectomy: a prospective comparison considering oncological and quality of life resultsHolger Borchers
Urological Clinic, Rheinisch-Westfalisch Technical University, Aachen, Germany
BJU Int 94:805-11. 2004..As approximately 18% of patients considered to be appropriate candidates for BT had tumours extending beyond the prostate capsule or invading the seminal vesicles, nomograms are needed for more accurate information before therapy... - Efficacy of unilateral nerve sparing in radical perineal prostatectomyBernhard Brehmer
Urological Clinic, University Clinic, Rheinisch-Westfalische Technische Hochschule Aachen, Aachen, Germany
Urol Int 74:308-14. 2005..However, the quality of erections is decreased, even in patients with erections sufficient for intercourse. Hence, appropriate sexual counseling in conjunction with medical therapy should be offered to all patients... - Quality of life following radical prostatectomyRuth Kirschner-Hermanns
Urological Clinic, University Clinic, , Pauwelsstrasse 30, Aachen, Germany
Crit Rev Oncol Hematol 43:141-51. 2002..Appropriate and honest counselling will have significant influence on the well being of the patient after completing therapy... - Bladder wall replacement by tissue engineering and autologous keratinocytes in minipigsBernhard Brehmer
Urological Clinic, University Clinic, Rheinisch Westfälische Technical University of Aachen, Pauwelsstrasse 30, 52074 Aachen, Germany
BJU Int 97:829-36. 2006.... - Erectile function after non-nerve-sparing radical prostatectomy: fact or fiction?Holger Borchers
Urological Clinic, University Clinic Aachen, Rheinisch Westfalisch Technical University, Aachen, Germany
Urol Int 76:213-6. 2006..To evaluate the potency in patients after radical perineal prostatectomy with wide excision of both neurovascular bundles... - Urethroplasty in female-to-male transsexualsDorothea Rohrmann
Urological Clinic, University Clinic Aachen, Pauwelsstrasse 30, D-52057 Aachen, Germany
Eur Urol 44:611-4. 2003..CONCLUSION: One-stage total phalloplasty and urethroplasty is associated with a significant rate of fistulas and strictures. However, these complications can be corrected by the techniques used in modern urethral surgery... - Therapy of local recurrence of renal cell carcinomaChristoph Wiesner
Department of Urology, Medical Faculty, University of Aachen, Aachen, Germany
Oncol Rep 9:189-92. 2002..2 months (7-15 months). In conclusion, surgery is recommended for treatment of LR. Additional benefit is not confirmed for any adjuctive therapy... - How to treat good risk prostate cancerHolger Borchers
Department of Urology, , Aachen, Germany
Curr Probl Cancer 27:40-4. 2003 - [Pro percutaneous-ablative tumor therapy]Bernhard Brehmer
Urologische Klinik,
Aktuelle Urol 38:101-3. 2007 - Fecal incontinence after radical perineal prostatectomy: a prospective studyRuth Kirschner-Hermanns
University Clinic of Urology, Technical University Aachen, Aachen, Germany
Urology 65:337-42. 2005..To assess, in a prospective study, the incidence of fecal incontinence after radical perineal prostatectomy... - Changes in bone structure after augmentation cystoplasty in chronic uraemic ratsDrasko Brkovic
Department of Urology, University Hospital of Aachen, Aachen, Germany
BJU Int 95:1066-70. 2005..To investigate the effect of urinary diversion using several types of intestinal segments on cortical and cancellous bone structure of growing rats with renal insufficiency... - High-grade Ta urothelial carcinoma and carcinoma in situ of the bladderRichard J Sylvester
European Organization for Research and Treatment of Cancer Data Center, Brussels, Belgium
Urology 66:90-107. 2005..These evidence-based guidelines have been developed to aid clinicians in the diagnosis and treatment of patients with high-grade Ta urothelial carcinoma and CIS... - Visualization of the basement membrane zone of the bladder by optical coherence tomography: feasibility of noninvasive evaluation of tumor invasionBarbara Hermes
Institute of Pathology, University Hospital RWTH Aachen, Aachen, Germany
Urology 72:677-81. 2008..Here, special focus is on the visualization of the basement membrane zone... - Identifying prostate carcinoma by MALDI-ImagingKristina Schwamborn
Institute of Pathology, RWTH Aachen University, 52074 Aachen, Germany
Int J Mol Med 20:155-9. 2007.... - Editorial comment on: The use of local anesthesia with N-DO injector (physion) for transurethral resection (TUR) of bladder tumors and bladder mapping: preliminary results and cost-effectiveness analysisGerhard Jakse
Eur Urol 52:1412-3. 2007 - Different types of scaffolds for reconstruction of the urinary tract by tissue engineeringBernhard Brehmer
Department of Urology, University Clinic Aachen, Aachen, Germany
Urol Int 78:23-9. 2007..We examined different scaffolds to select the ideal material for the reconstruction of the bladder wall by tissue engineering...