Matthias Jacob

Summary

Affiliation: University of Munich
Country: Germany

Publications

  1. ncbi request reprint [Determinants of insensible fluid loss. Perspiration, protein shift and endothelial glycocalyx]
    M Jacob
    Klinik fur Anaesthesiologie, Klinikum der Ludwig Maximilians Universität München Grosshadern Innenstadt, Nussbaumstrasse 20, 80336 Munchen
    Anaesthesist 56:747-58, 760-4. 2007
  2. doi request reprint A rational approach to perioperative fluid management
    Daniel Chappell
    Clinic of Anesthesiology, Ludwig Maximilians University, Munich, Germany
    Anesthesiology 109:723-40. 2008
  3. pmc Twisting and ignoring facts on hydroxyethyl starch is not very helpful
    Daniel Chappell
    Department of Anaesthesiology, University Hospital of Munich, Nußbaumstrasse 20, 80336 Munich, Germany
    Scand J Trauma Resusc Emerg Med 21:85. 2013
  4. doi request reprint Physiological levels of A-, B- and C-type natriuretic peptide shed the endothelial glycocalyx and enhance vascular permeability
    Matthias Jacob
    Department of Anesthesiology, University Hospital Munich, Nussbaumstrasse 20, 80336, Munich, Germany
    Basic Res Cardiol 108:347. 2013
  5. doi request reprint Effects of perioperative fasting on haemodynamics and intravascular volumes
    Matthias Jacob
    Department of Anaesthesiology, University Hospital Munich, Munich, Germany
    Best Pract Res Clin Anaesthesiol 26:421-30. 2012
  6. pmc Haematocrit is invalid for estimating red cell volume: a prospective study in male volunteers
    Matthias Jacob
    Department of Anaesthesiology, University Hospital of Munich, Munich, Germany
    Blood Transfus 10:471-9. 2012
  7. doi request reprint Albumin augmentation improves condition of guinea pig hearts after 4 hr of cold ischemia
    Matthias Jacob
    Clinic of Anesthesiology, Ludwig Maximilians Universitaet Muenchen, Munich, Germany
    Transplantation 87:956-65. 2009
  8. doi request reprint Current aspects of perioperative fluid handling in vascular surgery
    Matthias Jacob
    Clinic of Anaesthesiology, Ludwig Maximilians University of Munich, Munich, Germany
    Curr Opin Anaesthesiol 22:100-8. 2009
  9. doi request reprint Impact of the time window on plasma volume measurement with indocyanine green
    M Jacob
    Clinic of Anaesthesiology, Ludwig Maximilians University, Nussbaumstr 20, 80336 Munich, Germany
    Physiol Meas 29:761-70. 2008
  10. pmc Small-volume resuscitation with hyperoncotic albumin: a systematic review of randomized clinical trials
    Matthias Jacob
    Klinik fur Anasthesiologie, Ludwig Maximilians Universitat, Klinikum Grosshadern, Nussbaumstrasse 20, D 80336 Munich, Germany
    Crit Care 12:R34. 2008

Detail Information

Publications57

  1. ncbi request reprint [Determinants of insensible fluid loss. Perspiration, protein shift and endothelial glycocalyx]
    M Jacob
    Klinik fur Anaesthesiologie, Klinikum der Ludwig Maximilians Universität München Grosshadern Innenstadt, Nussbaumstrasse 20, 80336 Munchen
    Anaesthesist 56:747-58, 760-4. 2007
    ..Clinical studies have revealed a link between fluid restriction and improved outcome after major abdominal surgery...
  2. doi request reprint A rational approach to perioperative fluid management
    Daniel Chappell
    Clinic of Anesthesiology, Ludwig Maximilians University, Munich, Germany
    Anesthesiology 109:723-40. 2008
    ..Therefore, undifferentiated fluid handling may increase the shift toward the interstitial space. Using the right kind of fluid in appropriate amounts at the right time might improve patient outcome...
  3. pmc Twisting and ignoring facts on hydroxyethyl starch is not very helpful
    Daniel Chappell
    Department of Anaesthesiology, University Hospital of Munich, Nußbaumstrasse 20, 80336 Munich, Germany
    Scand J Trauma Resusc Emerg Med 21:85. 2013
    ..This is not a big problem, but has to be discussed carefully and honestly to prevent the data from being misinterpreted by users and official authorities. ..
  4. doi request reprint Physiological levels of A-, B- and C-type natriuretic peptide shed the endothelial glycocalyx and enhance vascular permeability
    Matthias Jacob
    Department of Anesthesiology, University Hospital Munich, Nussbaumstrasse 20, 80336, Munich, Germany
    Basic Res Cardiol 108:347. 2013
    ..These findings suggest participation of natriuretic peptides in pathophysiological processes like heart failure, inflammation or sepsis. Inhibition of metalloproteases might serve as a basis for future therapeutical options...
  5. doi request reprint Effects of perioperative fasting on haemodynamics and intravascular volumes
    Matthias Jacob
    Department of Anaesthesiology, University Hospital Munich, Munich, Germany
    Best Pract Res Clin Anaesthesiol 26:421-30. 2012
    ..It appears as though there are two important targets to preserve cardiac preload: normovolaemia and vasotension...
  6. pmc Haematocrit is invalid for estimating red cell volume: a prospective study in male volunteers
    Matthias Jacob
    Department of Anaesthesiology, University Hospital of Munich, Munich, Germany
    Blood Transfus 10:471-9. 2012
    ..A study challenging this convention systematically co-determined and compared these measures...
  7. doi request reprint Albumin augmentation improves condition of guinea pig hearts after 4 hr of cold ischemia
    Matthias Jacob
    Clinic of Anesthesiology, Ludwig Maximilians Universitaet Muenchen, Munich, Germany
    Transplantation 87:956-65. 2009
    ..The impact of augmenting a traditional preservation solution with plasma colloid albumin was therefore investigated...
  8. doi request reprint Current aspects of perioperative fluid handling in vascular surgery
    Matthias Jacob
    Clinic of Anaesthesiology, Ludwig Maximilians University of Munich, Munich, Germany
    Curr Opin Anaesthesiol 22:100-8. 2009
    ..There are only scarce data on this specialty, forcing the clinician to extrapolate existing data when planning perioperative fluid management. This review aims to summarize the underlying facts...
  9. doi request reprint Impact of the time window on plasma volume measurement with indocyanine green
    M Jacob
    Clinic of Anaesthesiology, Ludwig Maximilians University, Nussbaumstr 20, 80336 Munich, Germany
    Physiol Meas 29:761-70. 2008
    ..Thus, to estimate the initial distribution space of indocyanine green via monoexponential extrapolation, the first linear kinetic of indocyanine green decay should be taken...
  10. pmc Small-volume resuscitation with hyperoncotic albumin: a systematic review of randomized clinical trials
    Matthias Jacob
    Klinik fur Anasthesiologie, Ludwig Maximilians Universitat, Klinikum Grosshadern, Nussbaumstrasse 20, D 80336 Munich, Germany
    Crit Care 12:R34. 2008
    ..Small-volume resuscitation can rapidly correct hypovolemia. Hyperoncotic albumin solutions, long in clinical use, are suitable for small-volume resuscitation; however, their clinical benefits remain uncertain...
  11. doi request reprint Blood volume is normal after pre-operative overnight fasting
    M Jacob
    Clinic of Anaesthesiology, Ludwig Maximilians University Munich, Nussbaumstrasse 20, 80336 Munich, Germany
    Acta Anaesthesiol Scand 52:522-9. 2008
    ..Our study aimed to quantify total intravascular BV after fasting by direct measurements and to compare it with calculated normal values in comparable non-fasted patients...
  12. ncbi request reprint The endothelial glycocalyx prefers albumin for evoking shear stress-induced, nitric oxide-mediated coronary dilatation
    Matthias Jacob
    Clinic of Anesthesiology, Ludwig Maximilians University Munich, Munich, Germany
    J Vasc Res 44:435-43. 2007
    ..This should involve the endothelial glycocalyx (EG). A greater effect was expected of albumin versus hydroxyethyl starch (HES) perfusion, because albumin seals coronary leaks more effectively than HES in an EG-dependent way...
  13. ncbi request reprint Clinical update: perioperative fluid management
    Matthias Jacob
    Clinic of Anaesthesiology, Ludwig Maximilians University, Munich 80336, Germany
    Lancet 369:1984-6. 2007
  14. ncbi request reprint The endothelial glycocalyx affords compatibility of Starling's principle and high cardiac interstitial albumin levels
    Matthias Jacob
    Clinic of Anesthesiology, Ludwig Maximilians University Munich, Nussbaumstr 20, D 80336 Munich, Germany
    Cardiovasc Res 73:575-86. 2007
    ..To test the role of an oncotic pressure gradient across the endothelial glycocalyx with respect to extravasation of fluid and colloids and development of tissue edema in a whole organ setting...
  15. ncbi request reprint Technical and physiological background of plasma volume measurement with indocyanine green: a clarification of misunderstandings
    Matthias Jacob
    Klinik fur Anasthesiologie, Ludwig Maximilians Universitat Munchen, Nussbaumstr 20, D 80336 Munich, Germany
    J Appl Physiol (1985) 102:1235-42. 2007
    ..Nevertheless, the ICG-DT is a useful tool for determining PV, provided it is well understood by the investigator to enable correct interpretation of the results...
  16. doi request reprint Perspectives in microvascular fluid handling: does the distribution of coagulation factors in human myocardium comply with plasma extravasation in venular coronary segments?
    Matthias Jacob
    Clinic of Anesthesiology, Ludwig Maximilians University, Munich, Germany
    J Vasc Res 48:219-26. 2011
    ..The distribution of pro- and anti-coagulatively active factors in human heart tissue has now been determined in relation to the types of microvessels...
  17. ncbi request reprint The 'third space'--fact or fiction?
    Matthias Jacob
    Clinic of Anaesthesiology, Ludwig Maximilians Universitaet Muenchen, Nussbaumstrasse 20, 80336 Munich, Germany
    Best Pract Res Clin Anaesthesiol 23:145-57. 2009
    ..In summary, eradicating this notion from our minds could be a further key to achieving perioperative fluid optimisation...
  18. doi request reprint Antithrombin reduces shedding of the endothelial glycocalyx following ischaemia/reperfusion
    Daniel Chappell
    Clinic of Anesthesiology, Ludwig Maximilians University Munich, Nussbaumstrasse 20, 80336 Munich, Germany
    Cardiovasc Res 83:388-96. 2009
    ..We investigated the influence of antithrombin on glycocalyx subjected to ischaemia/reperfusion...
  19. ncbi request reprint Hydrocortisone preserves the vascular barrier by protecting the endothelial glycocalyx
    Daniel Chappell
    Clinic of Anesthesiology, Ludwig Maximilians University Munich, Munich, Germany
    Anesthesiology 107:776-84. 2007
    ..Healthy vascular endothelium is coated by the endothelial glycocalyx, diminution of which increases capillary permeability, suggesting that the glycocalyx is a target for hydrocortisone action...
  20. pmc Exogenous nitric oxide requires an endothelial glycocalyx to prevent postischemic coronary vascular leak in guinea pig hearts
    Dirk Bruegger
    Clinic of Anesthesiology, Ludwig Maximilians University, Marchioninistrasse 15, 81377 Munich, Germany
    Crit Care 12:R73. 2008
    ..The objective of this study was to investigate the effect of exogenous administration of NO during reperfusion on both coronary endothelial glycocalyx and vascular integrity...
  21. doi request reprint TNF-alpha induced shedding of the endothelial glycocalyx is prevented by hydrocortisone and antithrombin
    Daniel Chappell
    Clinic of Anaesthesiology, Ludwig Maximilians University, Nussbaumstrasse 20, Munich, Germany
    Basic Res Cardiol 104:78-89. 2009
    ..Our aim was to show whether hydrocortisone and antithrombin stabilize the glycocalyx and, therefore, the vascular barrier, against damage induced by the inflammatory stimulus TNF-alpha, thus improving the cardio-vascular situation...
  22. ncbi request reprint Heparinase selectively sheds heparan sulphate from the endothelial glycocalyx
    Daniel Chappell
    Clinic of Anaesthesiology, Ludwig Maximilians University, Nussbaumstr 20, D 80336 Munich
    Biol Chem 389:79-82. 2008
    ..We show by electron microscopy, immunohistological staining and quantitative measurements of the constituent parts, that heparinase selectively sheds heparan sulphate from the glycocalyx, but not the syndecans...
  23. ncbi request reprint Contrasting effects of colloid and crystalloid resuscitation fluids on cardiac vascular permeability
    Matthias Jacob
    Clinic of Anesthesiology, Ludwig Maximilians University Munich, Germany
    Anesthesiology 104:1223-31. 2006
    ..Albumin is presumed to interact with the endothelial glycocalyx. The authors' objective was to compare the impact of different resuscitation fluids (human albumin, hydroxyethyl starch, saline) on vascular integrity...
  24. doi request reprint Glycocalyx protection reduces leukocyte adhesion after ischemia/reperfusion
    Daniel Chappell
    Clinic of Anesthesiology, Ludwig Maximilians University Munich, Munich, Germany
    Shock 34:133-9. 2010
    ..Preservation of the glycocalyx mitigates postischemic PMN adhesion. Preconditioning with either hydrocortisone or antithrombin should, thus, alleviate vascular leakage, tissue edema, and inflammation...
  25. doi request reprint The glycocalyx of the human umbilical vein endothelial cell: an impressive structure ex vivo but not in culture
    Daniel Chappell
    Clinic of Anesthesiology, Ludwig Maximilians University, Nussbaumstrasse 20, 80336 Munich, Germany
    Circ Res 104:1313-7. 2009
    ..The presence of heparan sulfates and syndecan-1 also on cultured cells may explain why mechanotransduction phenomena can be observed even with a nonmature glycocalyx...
  26. doi request reprint Sevoflurane reduces leukocyte and platelet adhesion after ischemia-reperfusion by protecting the endothelial glycocalyx
    Daniel Chappell
    Clinic of Anesthesiology, Ludwig Maximilians University Munich, Munich, Germany
    Anesthesiology 115:483-91. 2011
    ..The authors analyzed a possible protective effect of sevoflurane on the glycocalyx and implications for postischemic cell adhesion...
  27. ncbi request reprint Shedding of the endothelial glycocalyx in patients undergoing major vascular surgery with global and regional ischemia
    Markus Rehm
    Clinic of Anesthesiology, Ludwig Maximilians University, Marchioninistrasse 15, 81377 Munich, Germany
    Circulation 116:1896-906. 2007
    ..As already demonstrated, this structure plays a key role in the regulation of inflammation and vascular permeability...
  28. doi request reprint Release of atrial natriuretic peptide precedes shedding of the endothelial glycocalyx equally in patients undergoing on- and off-pump coronary artery bypass surgery
    Dirk Bruegger
    Department of Anesthesiology, LMU Munich, Marchioninistrasse 15, 81377 Munich, Germany
    Basic Res Cardiol 106:1111-21. 2011
    ..These data suggest that release of ANP may lead to perturbation of the endothelial glycocalyx in both on- and off-pump coronary artery bypass surgery...
  29. ncbi request reprint Changes in acid-base balance following bolus infusion of 20% albumin solution in humans
    Dirk Bruegger
    Clinic of Anesthesiology, Ludwig Maximilians University, Marchioninistrasse 15, 81377 Munich, Germany
    Intensive Care Med 31:1123-7. 2005
    ..To evaluate changes in acid-base balance following bolus infusions of a 20% albumin solution...
  30. ncbi request reprint Endothelial glycocalyx as an additional barrier determining extravasation of 6% hydroxyethyl starch or 5% albumin solutions in the coronary vascular bed
    Markus Rehm
    Klinik fur Anasthesiologie, Ludwig Maximilians Universitat Munchen, Klinikum Grosshadern, Marchioninistr 15, D 81377 Munich, Germany
    Anesthesiology 100:1211-23. 2004
    ..The impact on the endothelial glycocalyx for the extravasation of colloidal infusion solutions has not been investigated sufficiently...
  31. ncbi request reprint Development and validation of a mathematical algorithm for quantifying preoperative blood volume by means of the decrease in hematocrit resulting from acute normovolemic hemodilution
    Matthias Jacob
    Anesthesiology Clinic, Ludwig Maximilians University, Munich, Germany
    Transfusion 45:562-71. 2005
    ..The interindividual variability of blood volume (BV) is high. The aim of this work was to use the decrease in large-vessel hematocrit (HK(LV)) during acute normovolemic hemodilution (ANH) as an instrument for estimating preoperative BV...
  32. ncbi request reprint [Exact measurement of the volume effect of 6% hydoxyethyl starch 130/0.4 (Voluven) during acute preoperative normovolemic hemodilution]
    M Jacob
    Klinik fur Anasthesiologie, Ludwig Maximilians Universitat, Klinikum Grosshadern, Munich
    Anaesthesist 52:896-904. 2003
    ..What is the effect of preoperative acute normovolemic hemodilution (ANH) with 6% hydroxyethyl starch (HES) 130/0.4 (Voluven) on blood volume?..
  33. doi request reprint Therapeutic strategies targeting the endothelial glycocalyx: acute deficits, but great potential
    Bernhard F Becker
    Department of Physiology, Walter Brendel Centre of Experimental Medicine, Ludwig Maximilians University, Schillerstrasse 44, Munich, Germany
    Cardiovasc Res 87:300-10. 2010
    ..Infusion of human plasma albumin (to maintain mechanical and chemical stability of the endothelial surface layer) seems the easiest treatment to implement...
  34. doi request reprint Endothelial glycocalyx and coronary vascular permeability: the fringe benefit
    Bernhard F Becker
    Walter Brendel Centre of Experimental Medicine, Ludwig Maximilians University Munich, Schillerstrasse 44, 80336, Munich, Germany
    Basic Res Cardiol 105:687-701. 2010
    ....
  35. ncbi request reprint Changes in blood volume and hematocrit during acute preoperative volume loading with 5% albumin or 6% hetastarch solutions in patients before radical hysterectomy
    M Rehm
    , , Klinikum Grosshadern, Munich, Germany
    Anesthesiology 95:849-56. 2001
    ....
  36. doi request reprint Reappraising Starling: the physiology of the microcirculation
    Matthias Jacob
    Department of Anaesthesiology, University Hospital Munich, Munich, Germany
    Curr Opin Crit Care 19:282-9. 2013
    ..Several contradictions to this principle have recently questioned its validity...
  37. doi request reprint Development of spontaneous subdural hematoma and bone marrow depression after hydroxyethyl starch administration
    Daniel Chappell
    Clinic of Anesthesiology, Ludwig Maximilians University Munich, Munich, Germany
    J Pediatr 153:579-81. 2008
  38. pmc Hydroxyethyl starch - the importance of being earnest
    Daniel Chappell
    Department of Anaesthesiology, University Hospital of Munich, Nussbaumstrasse 20, 80336 Munich, Germany
    Scand J Trauma Resusc Emerg Med 21:61. 2013
    ..An authority being able to dictate behavior should stand clear from oppressively ending a worldwide expert discussion and step back into the role of the observer until science achieves an agreement...
  39. pmc Influence of an acetate- and a lactate-based balanced infusion solution on acid base physiology and hemodynamics: an observational pilot study
    Klaus F Hofmann-Kiefer
    Clinic of Anesthesiology, Ludwig Maximilians University, City of Munich, Germany
    Eur J Med Res 17:21. 2012
    ..Because adverse hemodynamic effects have been reported when using acetate buffered solutions in hemodialysis, hemodynamics were also evaluated...
  40. pmc Causes of metabolic acidosis in canine hemorrhagic shock: role of unmeasured ions
    Dirk Bruegger
    Clinic of Anesthesiology, Ludwig Maximilians University, Marchioninistrasse 15, 81377 Munich, Germany
    Crit Care 11:R130. 2007
    ..Metabolic acidosis during hemorrhagic shock is common and conventionally considered to be due to hyperlactatemia. There is increasing awareness, however, that other nonlactate, unmeasured anions contribute to this type of acidosis...
  41. ncbi request reprint Effect of hypertonic saline dextran on acid-base balance in patients undergoing surgery of abdominal aortic aneurysm
    Dirk Bruegger
    Clinic of Anesthesiology, Ludwig Maximilians University Munich, Germany
    Crit Care Med 33:556-63. 2005
    ..To evaluate the magnitude and cause of metabolic acidosis after infusion of 7.5% sodium chloride 6% dextran 70...
  42. doi request reprint [Perioperative metabolism control of diabetic and non-diabetic patients]
    Dennis A Ballwieser
    Klinik für Anaesthesiologie am Klinikum, der Universität München, Germany
    Anasthesiol Intensivmed Notfallmed Schmerzther 46:258-66; quiz 267. 2011
    ..Oral antidiabetics used in Germany, different classes of insulins and possible regimes for the intraoperative management of insulin therapies and important aspects of the postoperative management are presented...
  43. doi request reprint [Options and limits of interscalene nerve blocks]
    Klaus Hofmann-Kiefer
    Klinik für Anaesthesiologie der Universität München
    Anasthesiol Intensivmed Notfallmed Schmerzther 44:522-9. 2009
    ..When carried out as a catheter-technique they provide a high quality postoperative pain therapy...
  44. doi request reprint [Hypernatremic alkalosis. Possible counterpart of hyperchloremic acidosis in intensive care patients?]
    K F Hofmann-Kiefer
    Klinik fur Anaesthesiologie, Intensivmedizin und Schmerztherapie, Ludwig Maximilians Universitat, Klinikum Innenstadt, 80337 München
    Anaesthesist 58:1210-5. 2009
    ..It is unknown whether hypernatremia plays a corresponding role with respect to the development of alkalosis...
  45. ncbi request reprint [Acute "normovolemic" hemodilution with 3.5% polygel (Haemaccel) for patients in the Wertheim-Meigs-operation. Blood loss of 87% blood volume without perioperative blood transfusion]
    M Rehm
    Klinik fur Anasthesiologie, Ludwig Maximilians Universitat, Klinikum Grosshadern, Munchen
    Anaesthesist 50:580-4. 2001
    ..Is polygeline (Haemaccel) a suitable colloid to perform preoperative acute normovolemic hemodilution (ANH) and to replace a large intraoperative blood loss?..
  46. doi request reprint Sevoflurane preserves the endothelial glycocalyx against ischaemia-reperfusion injury
    T Annecke
    Clinic of Anaesthesiology, Ludwig Maximilians University Munich, Germany
    Br J Anaesth 104:414-21. 2010
    ..We evaluated the effect of cardiac pre- and post-conditioning with sevoflurane on integrity of the endothelial glycocalyx in conjunction with coronary vascular function...
  47. doi request reprint [Expedition glycocalyx. A newly discovered "Great Barrier Reef"]
    D Chappell
    Klinik fur Anaesthesiologie, Klinikum der Ludwig Maximilians Universität, Nussbaumstr 20, 80336 Munchen, Deutschland
    Anaesthesist 57:959-69. 2008
    ..Recent studies have shown that protecting this structure not only maintains the vascular barrier, but constitutes an important component of a rational perioperative fluid therapy...
  48. doi request reprint [Emergency room management of severely injured patients]
    C Siebers
    Klinik fur Anaesthesiologie, Campus Innenstadt, Klinikum der Universitat Munchen, 80336 Munchen
    Anaesthesist 58:1216-22. 2009
    ..Clinical algorithms can potentially decrease the rate of complications and errors. The purpose of this study was to investigate the incidence of deviations from a multislice computed tomography based trauma room algorithm...
  49. ncbi request reprint Influence of non-ventilatory options on postoperative outcome
    Daniel Chappell
    Clinic of Anesthesiology, Ludwig Maximilians University, Nussbaumstrasse 20, 80336 Munich, Germany
    Best Pract Res Clin Anaesthesiol 24:267-81. 2010
    ..Further development of surgical minimally invasive techniques and ongoing evaluation of procedure-specific strategies is urgently warranted...
  50. doi request reprint The impact of the glycocalyx on microcirculatory oxygen distribution in critical illness
    Daniel Chappell
    Clinic of Anaesthesiology, Ludwig Maximilians University Munich, Munich, Germany
    Curr Opin Anaesthesiol 22:155-62. 2009
    ..Main problems of critical illness and sepsis are an altered oxygen distribution and microvascular dysfunction linked to tissue oedema. This review seeks to analyse the role of the endothelial glycocalyx in this context...
  51. ncbi request reprint [Metabolic alkalosis despite hyperlactatemia and hypercapnia. Interpretation and therapy with help of the Stewart concept]
    D Chappell
    Klinik fur Anasthesiologie, Universitätsklinikum der Ludwig Maximilians Universität, Nussbaumstrasse 20, 80336 Munchen
    Anaesthesist 57:139-42. 2008
    ..The modern Stewart concept provides enhanced information, enabling an exact diagnosis and causal therapy even in complex cases...
  52. ncbi request reprint [Anaesthesia for primary cesarean section in a patient with an extensive cerebral arteriovenous malformation]
    M Jacob
    Klinik fur Anasthesiologie, Ludwig Maximilians Universitat, Klinikum Grosshadern, Munich
    Anaesthesist 52:929-33. 2003
    ..Two months later she came back to hospital with an acute severe headache. After CT-diagnosis of an acute subarachnoid hemorrhage she underwent an emergency craniotomy...
  53. ncbi request reprint Atrial natriuretic peptide induces shedding of endothelial glycocalyx in coronary vascular bed of guinea pig hearts
    Dirk Bruegger
    Clinic for Anesthesiology, Ludwig Maximilians Univ, Marchioninistr 15, D 81377 Munich, Germany
    Am J Physiol Heart Circ Physiol 289:H1993-9. 2005
    ..Thus the permeability-increasing effect of ANP may be at least partially related to changes in the integrity of the endothelial glycocalyx...
  54. ncbi request reprint Genetical analbuminemia is not an appropriate model for hypoalbuminemia in critically ill patients
    Daniel Chappell
    Chest 132:1717-8; author reply 1718. 2007
  55. ncbi request reprint Saline or albumin for fluid resuscitation in traumatic brain injury
    Matthias Jacob
    N Engl J Med 357:2634-5; author reply 2635-6. 2007
  56. doi request reprint Preoperative bowel preparation
    Daniel Chappell
    Lancet 371:1661; author reply 1662. 2008