Sabina Illi

Summary

Affiliation: University of Munich
Country: Germany

Publications

  1. doi request reprint Perinatal influences on the development of asthma and atopy in childhood
    Sabina Illi
    University Children s Hospital, Munich, Germany Electronic address
    Ann Allergy Asthma Immunol 112:132-139.e1. 2014
  2. doi request reprint Protection from childhood asthma and allergy in Alpine farm environments-the GABRIEL Advanced Studies
    Sabina Illi
    Asthma and Allergy Research Group, University Children s Hospital, Munich, Germany
    J Allergy Clin Immunol 129:1470-7.e6. 2012
  3. ncbi request reprint Perennial allergen sensitisation early in life and chronic asthma in children: a birth cohort study
    Sabina Illi
    Department of Pediatric Pneumology and Immunology, Charite Universitatsmedizin Berlin, Germany
    Lancet 368:763-70. 2006
  4. doi request reprint Regulation of TH17 markers early in life through maternal farm exposure
    Anna Lluis
    Department of Pulmonary and Allergy, University Children s Hospital Munich, LMU Munich, Munich, Germany
    J Allergy Clin Immunol 133:864-71. 2014
  5. ncbi request reprint The natural course of atopic dermatitis from birth to age 7 years and the association with asthma
    Sabina Illi
    Department of Pediatric Pneumology and Immunology, Charite, Dr von Haunersches Kinderspital, Lindwurmastrasse 4, 80337 Munich, Germany
    J Allergy Clin Immunol 113:925-31. 2004
  6. doi request reprint Maternal farm exposure modulates neonatal immune mechanisms through regulatory T cells
    Bianca Schaub
    Department of Pulmonary and Allergy, University Children s Hospital Munich, LMU Munich, Munich, Germany
    J Allergy Clin Immunol 123:774-82.e5. 2009
  7. doi request reprint Exposure to environmental microorganisms and childhood asthma
    Markus J Ege
    University Children s Hospital Munich, Munich, Germany
    N Engl J Med 364:701-9. 2011
  8. pmc T regulatory cells in cord blood--FOXP3 demethylation as reliable quantitative marker
    Jing Liu
    Department of Pulmonary and Allergy, University Children s Hospital Munich, Ludwig Maximilians Universitat Munich, Munich, Germany
    PLoS ONE 5:e13267. 2010
  9. doi request reprint Gene-environment interaction for childhood asthma and exposure to farming in Central Europe
    Markus J Ege
    University Children s Hospital Munich, Munich, Germany
    J Allergy Clin Immunol 127:138-44, 144.e1-4. 2011
  10. ncbi request reprint The GABRIEL Advanced Surveys: study design, participation and evaluation of bias
    Jon Genuneit
    Institute of Epidemiology and Medical Biometry, Ulm University, Ulm LMU Munich, University Children s Hospital, Munich, Germany
    Paediatr Perinat Epidemiol 25:436-47. 2011

Collaborators

Detail Information

Publications24

  1. doi request reprint Perinatal influences on the development of asthma and atopy in childhood
    Sabina Illi
    University Children s Hospital, Munich, Germany Electronic address
    Ann Allergy Asthma Immunol 112:132-139.e1. 2014
    ..However, only a small part of this burden of disease established early in life has been explained...
  2. doi request reprint Protection from childhood asthma and allergy in Alpine farm environments-the GABRIEL Advanced Studies
    Sabina Illi
    Asthma and Allergy Research Group, University Children s Hospital, Munich, Germany
    J Allergy Clin Immunol 129:1470-7.e6. 2012
    ..However, no single specific farm-related exposure explaining this protective farm effect has consistently been identified...
  3. ncbi request reprint Perennial allergen sensitisation early in life and chronic asthma in children: a birth cohort study
    Sabina Illi
    Department of Pediatric Pneumology and Immunology, Charite Universitatsmedizin Berlin, Germany
    Lancet 368:763-70. 2006
    ..Unknown factors between birth and school age determine the progressive loss of pulmonary function in children with persistent asthma. We investigated the role of allergic sensitisation and allergen exposure early in life...
  4. doi request reprint Regulation of TH17 markers early in life through maternal farm exposure
    Anna Lluis
    Department of Pulmonary and Allergy, University Children s Hospital Munich, LMU Munich, Munich, Germany
    J Allergy Clin Immunol 133:864-71. 2014
    ..However, the underlying mechanisms might involve immune modulation of additional T-cell populations, such as TH17 cells, influenced by genetic predisposition...
  5. ncbi request reprint The natural course of atopic dermatitis from birth to age 7 years and the association with asthma
    Sabina Illi
    Department of Pediatric Pneumology and Immunology, Charite, Dr von Haunersches Kinderspital, Lindwurmastrasse 4, 80337 Munich, Germany
    J Allergy Clin Immunol 113:925-31. 2004
    ..Atopic dermatitis (AD) is considered to be one of the first manifestations in the atopic march. However, few prospective studies on AD and its association with childhood asthma exist...
  6. doi request reprint Maternal farm exposure modulates neonatal immune mechanisms through regulatory T cells
    Bianca Schaub
    Department of Pulmonary and Allergy, University Children s Hospital Munich, LMU Munich, Munich, Germany
    J Allergy Clin Immunol 123:774-82.e5. 2009
    ..Cross-sectional studies suggest that maternal exposure to farming decreases the risk of allergic diseases in offspring. The potential underlying immunologic mechanisms are not understood...
  7. doi request reprint Exposure to environmental microorganisms and childhood asthma
    Markus J Ege
    University Children s Hospital Munich, Munich, Germany
    N Engl J Med 364:701-9. 2011
    ..In previous studies, markers of microbial exposure have been inversely related to these conditions...
  8. pmc T regulatory cells in cord blood--FOXP3 demethylation as reliable quantitative marker
    Jing Liu
    Department of Pulmonary and Allergy, University Children s Hospital Munich, Ludwig Maximilians Universitat Munich, Munich, Germany
    PLoS ONE 5:e13267. 2010
    ..We assessed FOXP3 demethylation in cord blood in relation to previously used Treg markers such as CD4+CD25(hi), FOXP3 mRNA, protein expression, and suppressive Treg function...
  9. doi request reprint Gene-environment interaction for childhood asthma and exposure to farming in Central Europe
    Markus J Ege
    University Children s Hospital Munich, Munich, Germany
    J Allergy Clin Immunol 127:138-44, 144.e1-4. 2011
    ..The farming environment has consistently been associated with protection from childhood asthma and atopy, and interactions have been reported with polymorphisms in innate immunity genes...
  10. ncbi request reprint The GABRIEL Advanced Surveys: study design, participation and evaluation of bias
    Jon Genuneit
    Institute of Epidemiology and Medical Biometry, Ulm University, Ulm LMU Munich, University Children s Hospital, Munich, Germany
    Paediatr Perinat Epidemiol 25:436-47. 2011
    ..The GABRIEL Advanced Surveys have created extensive collections of questionnaire data, biomaterial and environmental samples promising new insights into this area of research...
  11. doi request reprint IL10 polymorphisms influence neonatal immune responses, atopic dermatitis, and wheeze at age 3 years
    Diana Raedler
    University Children s Hospital Munich, Department of Pulmonary and Allergy, LMU Munich, Munich, Germany
    J Allergy Clin Immunol 131:789-96. 2013
    ..Several IL10 single nucleotide polymorphisms (SNPs) were associated with inflammatory diseases, such as atopic diseases, which might have their onset during early immune maturation...
  12. pmc TBX21 and HLX1 polymorphisms influence cytokine secretion at birth
    Vera Isabel Casaca
    Department of Pulmonary and Allergy, University Childrens Hospital Munich, Munich, Germany
    PLoS ONE 7:e31069. 2012
    ..This study investigated the influence of TBX21 and HLX1 single nucleotide polymorphisms (SNPs), which have previously been shown to be associated with asthma, on T(H)1/T(H)2 lineage cytokines at birth...
  13. ncbi request reprint The development of childhood asthma: lessons from the German Multicentre Allergy Study (MAS)
    Susanne Lau
    University Children s Hospital, Department of Pneumology and Immunology Berlin, Charite Campus Virchow, Augustenburger Platz 1, 13353 Berlin, Germany
    Paediatr Respir Rev 3:265-72. 2002
    ....
  14. ncbi request reprint Transient suppression of atopy in early childhood is associated with high vaccination coverage
    Christoph Gruber
    Department of Pediatric Pneumology and Immunology, Charite Humboldt University, Berlin, Germany
    Pediatrics 111:e282-8. 2003
    ..To analyze prevalences of allergic sensitization and atopic disease in relation to vaccination coverage...
  15. doi request reprint Allergic rhinitis as a predictor for wheezing onset in school-aged children
    Mascha K Rochat
    Children s Hospital, University of Munich, Munich, Germany
    J Allergy Clin Immunol 126:1170-5.e2. 2010
    ..These findings suggest an interaction between the upper and lower airways. Whether rhinitis is a predictor for childhood-onset asthma is unknown...
  16. doi request reprint Maternal vitamin D intake during pregnancy increases gene expression of ILT3 and ILT4 in cord blood
    M K Rochat
    Children s Hospital, University of Munich, Lindwurmstrasse 4, Munich, Germany
    Clin Exp Allergy 40:786-94. 2010
    ..Vitamin D has been shown to induce tolerogenic antigen-presenting cells such as dendritic cells. Whether the allergy-protective potential of prenatal vitamin D is mediated through such mechanisms is, however, unknown...
  17. doi request reprint Prenatal exposure to a farm environment modifies atopic sensitization at birth
    Markus Johannes Ege
    University Children s Hospital, Munich, Germany
    J Allergy Clin Immunol 122:407-12, 412.e1-4. 2008
    ..Previous cross-sectional surveys have suggested that maternal exposure to animal sheds during pregnancy exerted a protective effect on atopic sensitization in children lasting until school age...
  18. doi request reprint ICOS-gene variants are not associated with atopic disease susceptibility in European children
    Katja C Beier
    Department of Paediatric Pneumology and Immunology, Charite Universitatsmedizin Berlin, Campus Virchow Klinikum, Berlin, Germany
    Pediatr Allergy Immunol 20:242-5. 2009
    ..Our data suggest that these ICOS variants do not play a major role in the development of atopy in European children...
  19. pmc Novel statistical approaches for non-normal censored immunological data: analysis of cytokine and gene expression data
    Nikolaus Ballenberger
    University Children s Hospital Munich, Department of Pulmonary and Allergy, LMU Munich, Munich, Germany
    PLoS ONE 7:e46423. 2012
    ..Additionally, complex and multiple immunological relationships need to be adjusted for potential confounding and interaction effects...
  20. doi request reprint Specific IgE to allergens in cord blood is associated with maternal immunity to Toxoplasma gondii and rubella virus
    M J Ege
    University Children s Hospital, Munich, Germany
    Allergy 63:1505-11. 2008
    ..Various studies have found reduced prevalences of atopic sensitization and atopic diseases in children previously exposed to infections or living conditions with a high microbial burden, such as the farming environment...
  21. doi request reprint Impairment of T-regulatory cells in cord blood of atopic mothers
    Bianca Schaub
    Department of Pulmonary and Allergy, University Children s Hospital Munich, Munich, Germany
    J Allergy Clin Immunol 121:1491-9, 1499.e1-13. 2008
    ..The underlying mechanisms are ill defined, yet regulatory T (Treg) and T(H)17 cells may play a key role potentially shaping the early immune system toward a proallergic or antiallergic immune regulation...
  22. ncbi request reprint Messages from the German Multicentre Allergy Study
    Renate Nickel
    Department for Pediatric Pneumology and Immunology, Charite, Berlin, Germany
    Pediatr Allergy Immunol 13:7-10. 2002
    ..Furthermore, candidate gene studies of atopic dermatitis and increased total serum IgE levels on chromosomes 5q, 12q and 17q in MAS-children and their parents are outlined...
  23. ncbi request reprint House-dust mite allergen exposure and the development of asthma in children
    Sabina Illi
    Ann Allergy Asthma Immunol 90:6-7. 2003
  24. ncbi request reprint T(H)1/T(H)2 immune response profiles differ between atopic children in eastern and western Germany
    Harald Renz
    Clinical Chemistry and Molecular Diagnostics, University Hospital Marburg, Germany
    J Allergy Clin Immunol 109:338-42. 2002
    ..Lower prevalence rates for childhood respiratory allergies have been reported in eastern Germany than in western Germany...