Research Topics
Species | Sabina IlliSummaryAffiliation: University of Munich Country: Germany Publications
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Detail Information
Publications
Protection from childhood asthma and allergy in Alpine farm environments-the GABRIEL Advanced StudiesSabina Illi
Asthma and Allergy Research Group, University Children s Hospital, Munich, Germany
J Allergy Clin Immunol 129:1470-7.e6. 2012..However, no single specific farm-related exposure explaining this protective farm effect has consistently been identified...
Perennial allergen sensitisation early in life and chronic asthma in children: a birth cohort studySabina Illi
Department of Pediatric Pneumology and Immunology, Charite Universitatsmedizin Berlin, Germany
Lancet 368:763-70. 2006..Unknown factors between birth and school age determine the progressive loss of pulmonary function in children with persistent asthma. We investigated the role of allergic sensitisation and allergen exposure early in life...- Maternal farm exposure modulates neonatal immune mechanisms through regulatory T cellsBianca Schaub
Department of Pulmonary and Allergy, University Children s Hospital Munich, LMU Munich, Munich, Germany
J Allergy Clin Immunol 123:774-82.e5. 2009..Cross-sectional studies suggest that maternal exposure to farming decreases the risk of allergic diseases in offspring. The potential underlying immunologic mechanisms are not understood... - Exposure to environmental microorganisms and childhood asthmaMarkus J Ege
University Children s Hospital Munich, Munich, Germany
N Engl J Med 364:701-9. 2011..In previous studies, markers of microbial exposure have been inversely related to these conditions... - The natural course of atopic dermatitis from birth to age 7 years and the association with asthmaSabina Illi
Department of Pediatric Pneumology and Immunology, Charit, Dr von Haunersches Kinderspital, Lindwurmastrasse 4, 80337 Munich, Germany
J Allergy Clin Immunol 113:925-31. 2004..Children with AD and wheeze have a marked loss in lung function, suggesting a distinct phenotype rather than a progressive development from AD to asthma... - Gene-environment interaction for childhood asthma and exposure to farming in Central EuropeMarkus J Ege
University Children s Hospital Munich, Munich, Germany
J Allergy Clin Immunol 127:138-44, 144.e1-4. 2011..The farming environment has consistently been associated with protection from childhood asthma and atopy, and interactions have been reported with polymorphisms in innate immunity genes... 
T regulatory cells in cord blood--FOXP3 demethylation as reliable quantitative markerJing Liu
Department of Pulmonary and Allergy, University Children s Hospital Munich, Ludwig Maximilians Universitat Munich, Munich, Germany
PLoS ONE 5:e13267. 2010..We assessed FOXP3 demethylation in cord blood in relation to previously used Treg markers such as CD4+CD25(hi), FOXP3 mRNA, protein expression, and suppressive Treg function...- The GABRIEL Advanced Surveys: study design, participation and evaluation of biasJon Genuneit
Institute of Epidemiology and Medical Biometry, Ulm University, Ulm LMU Munich, University Children s Hospital, Munich, Germany
Paediatr Perinat Epidemiol 25:436-47. 2011..The GABRIEL Advanced Surveys have created extensive collections of questionnaire data, biomaterial and environmental samples promising new insights into this area of research... - Transient suppression of atopy in early childhood is associated with high vaccination coverageChristoph Gruber
Department of Pediatric Pneumology and Immunology, Charite Humboldt University, Berlin, Germany
Pediatrics 111:e282-8. 2003..To analyze prevalences of allergic sensitization and atopic disease in relation to vaccination coverage... - TBX21 and HLX1 polymorphisms influence cytokine secretion at birthVera Isabel Casaca
Department of Pulmonary and Allergy, University Childrens Hospital Munich, Munich, Germany
PLoS ONE 7:e31069. 2012..This study investigated the influence of TBX21 and HLX1 single nucleotide polymorphisms (SNPs), which have previously been shown to be associated with asthma, on T(H)1/T(H)2 lineage cytokines at birth... - The development of childhood asthma: lessons from the German Multicentre Allergy Study (MAS)Susanne Lau
University Children s Hospital, Department of Pneumology and Immunology Berlin, Charite Campus Virchow, Augustenburger Platz 1, 13353 Berlin, Germany
Paediatr Respir Rev 3:265-72. 2002.... - Prenatal exposure to a farm environment modifies atopic sensitization at birthMarkus Johannes Ege
University Children s Hospital, Munich, Germany
J Allergy Clin Immunol 122:407-12, 412.e1-4. 2008..Previous cross-sectional surveys have suggested that maternal exposure to animal sheds during pregnancy exerted a protective effect on atopic sensitization in children lasting until school age... - Maternal vitamin D intake during pregnancy increases gene expression of ILT3 and ILT4 in cord bloodM K Rochat
Children s Hospital, University of Munich, Lindwurmstrasse 4, Munich, Germany
Clin Exp Allergy 40:786-94. 2010..Vitamin D has been shown to induce tolerogenic antigen-presenting cells such as dendritic cells. Whether the allergy-protective potential of prenatal vitamin D is mediated through such mechanisms is, however, unknown... - ICOS-gene variants are not associated with atopic disease susceptibility in European childrenKatja C Beier
Department of Paediatric Pneumology and Immunology, Charite Universitatsmedizin Berlin, Campus Virchow Klinikum, Berlin, Germany
Pediatr Allergy Immunol 20:242-5. 2009..Our data suggest that these ICOS variants do not play a major role in the development of atopy in European children... - Allergic rhinitis as a predictor for wheezing onset in school-aged childrenMascha K Rochat
Children s Hospital, University of Munich, Munich, Germany
J Allergy Clin Immunol 126:1170-5.e2. 2010..These findings suggest an interaction between the upper and lower airways. Whether rhinitis is a predictor for childhood-onset asthma is unknown... - Novel statistical approaches for non-normal censored immunological data: analysis of cytokine and gene expression dataNikolaus Ballenberger
University Children s Hospital Munich, Department of Pulmonary and Allergy, LMU Munich, Munich, Germany
PLoS ONE 7:e46423. 2012..Additionally, complex and multiple immunological relationships need to be adjusted for potential confounding and interaction effects... - Specific IgE to allergens in cord blood is associated with maternal immunity to Toxoplasma gondii and rubella virusM J Ege
University Children s Hospital, Munich, Germany
Allergy 63:1505-11. 2008..Various studies have found reduced prevalences of atopic sensitization and atopic diseases in children previously exposed to infections or living conditions with a high microbial burden, such as the farming environment... - Impairment of T-regulatory cells in cord blood of atopic mothersBianca Schaub
Department of Pulmonary and Allergy, University Children s Hospital Munich, Munich, Germany
J Allergy Clin Immunol 121:1491-9, 1499.e1-13. 2008..The underlying mechanisms are ill defined, yet regulatory T (Treg) and T(H)17 cells may play a key role potentially shaping the early immune system toward a proallergic or antiallergic immune regulation... - Messages from the German Multicentre Allergy StudyRenate Nickel
Department for Pediatric Pneumology and Immunology, Charite, Berlin, Germany
Pediatr Allergy Immunol 13:7-10. 2002..Furthermore, candidate gene studies of atopic dermatitis and increased total serum IgE levels on chromosomes 5q, 12q and 17q in MAS-children and their parents are outlined... - House-dust mite allergen exposure and the development of asthma in childrenSabina Illi
Ann Allergy Asthma Immunol 90:6-7. 2003 - T(H)1/T(H)2 immune response profiles differ between atopic children in eastern and western GermanyHarald Renz
Clinical Chemistry and Molecular Diagnostics, University Hospital Marburg, Germany
J Allergy Clin Immunol 109:338-42. 2002..CONCLUSIONS: This is the first epidemiologic survey to demonstrate regional differences in the T(H)1/T(H)2 response pattern and their relation to atopic disease between regions...