Research Topics
| Martin J HugSummaryAffiliation: University Hospital Country: Germany Publications
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Detail Information
Publications
Kinetic targeting of pegylated liposomal doxorubicin: a new approach to reduce toxicity during chemotherapy (CARL-trial)Jürgen Eckes
Medical Practice, Altdorfstr 10, Emmendingen, Germany
BMC Cancer 11:337. 2011..Once saturation in tumor tissue is achieved, most of the administered DDS still circulate in the plasma. The extracorporeal elimination of these circulating nanoparticles would probably reduce toxicity...
Measurement of ion transport function in rectal biopsiesMartin J Hug
Pharmacy, University Medical Center Freiburg, D 79106, Freiburg, Germany
Methods Mol Biol 741:87-107. 2011..In this chapter we will review the different approaches to perform ion transport measurements and try to highlight the advantages and limitations of these techniques...
How to measure CFTR-dependent bicarbonate transport: from single channels to the intact epitheliumMartin J Hug
Pharmacy, University Medical Center Freiburg, Freiburg, Germany
Methods Mol Biol 741:489-509. 2011..In this chapter we will review some of the techniques available to measure bicarbonate transport through single ion channels, individual cells, and intact epithelial layers...
Controlled application and scheduled removal of nanoparticle based chemotherapeutics (CARL) will reduce dose limiting adverse events in anticancer chemotherapyGerhard Putz
University Freiburg Medical Center, Department Clinical Chemistry, Hugstetter Street 55, D 79106 Freiburg, Germany
Med Hypotheses 72:393-7. 2009..In conclusion, the combination of DDS and scheduled apheresis may allow the development of new chemotherapy regiments with higher impact and/or less toxicity...
Controlled application and removal of liposomal therapeutics: effective elimination of pegylated liposomal doxorubicin by double-filtration plasmapheresis in vitroGerhard Putz
Department of Clinical Chemistry, University Medical Center Freiburg, Freiburg, Germany
J Clin Apher 25:54-62. 2010..Finding a way to detoxify the predominant part of a given dose, circulating in the blood after accumulation is completed, will presumably reduce severe side effects during chemotherapy...
