Roman Huber

Summary

Affiliation: University Hospital
Country: Germany

Publications

  1. pmc Quality of life, immunomodulation and safety of adjuvant mistletoe treatment in patients with gastric carcinoma - a randomized, controlled pilot study
    Kab Choong Kim
    Division of Stomach surgery, Department of Surgery, Asan Medical Center, College of Medicine, University of Ulsan, Seoul, Korea
    BMC Complement Altern Med 12:172. 2012
  2. doi request reprint Pharmacokinetics of natural mistletoe lectins after subcutaneous injection
    Roman Huber
    Department of Environmental Health Sciences, University Hospital Freiburg, Breisacher Str 115B, 79106 Freiburg, Germany
    Eur J Clin Pharmacol 66:889-97. 2010
  3. pmc Effects of abdominal hot compresses on indocyanine green elimination--a randomized cross over study in healthy subjects
    Roman Huber
    Department of Internal Medicine II, Freiburg University Hospital, Germany
    BMC Gastroenterol 7:27. 2007
  4. doi request reprint Artichoke leave extract for chronic hepatitis C - a pilot study
    R Huber
    Center for Complementary Medicine, University Hospital Freiburg, Freiburg, Germany
    Phytomedicine 16:801-4. 2009
  5. ncbi request reprint In vitro immunoreactivity towards lectin-rich or viscotoxin-rich mistletoe (Viscum album L.) extracts Iscador applied to healthy individuals
    Roman Huber
    Centre for Complementary Medicine Department of Internal Medicine II, University of Freiburg, Germany
    Arzneimittelforschung 56:447-56. 2006
  6. ncbi request reprint Tormentil for active ulcerative colitis: an open-label, dose-escalating study
    Roman Huber
    Department for Internal Medicine II, University Hospital Freiburg, Germany
    J Clin Gastroenterol 41:834-8. 2007
  7. doi request reprint Effectiveness of subcutaneous injections of a cartilage preparation in osteoarthritis of the knee--a randomized, placebo controlled phase II study
    Roman Huber
    Department of Environmental Health Sciences, University Hospital Freiburg, Breisacher Str 115B, D 79106 Freiburg, Germany
    Complement Ther Med 18:113-8. 2010
  8. doi request reprint Cupping - is it reproducible? Experiments about factors determining the vacuum
    R Huber
    Center for Complementqry Medicine, Department of Environmental Health Sciences, University Hospital Freiburg, Breisacher Str 115B, D 79106 Freiburg, Germany
    Complement Ther Med 19:78-83. 2011
  9. doi request reprint Arnica and stinging nettle for treating burns - a self-experiment
    Roman Huber
    Center for Complementary Medicine, Department of Environmental Health Sciences, University Hospital Freiburg, Germany
    Complement Ther Med 19:276-80. 2011
  10. pmc Safety and effects of two mistletoe preparations on production of Interleukin-6 and other immune parameters - a placebo controlled clinical trial in healthy subjects
    Roman Huber
    Uni Zentrum Naturheilkunde, University Medical Center Freiburg, Germany
    BMC Complement Altern Med 11:116. 2011

Collaborators

Detail Information

Publications28

  1. pmc Quality of life, immunomodulation and safety of adjuvant mistletoe treatment in patients with gastric carcinoma - a randomized, controlled pilot study
    Kab Choong Kim
    Division of Stomach surgery, Department of Surgery, Asan Medical Center, College of Medicine, University of Ulsan, Seoul, Korea
    BMC Complement Altern Med 12:172. 2012
    ..Mistletoe (Viscum album L.) extracts are widely used in complementary cancer therapy. Aim of this study was to evaluate safety and efficacy of a standardized mistletoe extract (abnobaVISCUM(®) Quercus, aVQ) in patients with gastric cancer...
  2. doi request reprint Pharmacokinetics of natural mistletoe lectins after subcutaneous injection
    Roman Huber
    Department of Environmental Health Sciences, University Hospital Freiburg, Breisacher Str 115B, 79106 Freiburg, Germany
    Eur J Clin Pharmacol 66:889-97. 2010
    ..This open-label, phase I, monocenter clinical trial was performed in order to describe the pharmacokinetics of nML...
  3. pmc Effects of abdominal hot compresses on indocyanine green elimination--a randomized cross over study in healthy subjects
    Roman Huber
    Department of Internal Medicine II, Freiburg University Hospital, Germany
    BMC Gastroenterol 7:27. 2007
    ..Hot compresses on the right upper abdomen are used as support for patients with liver diseases in Germany. The study was designed to determine, whether they affect hepatic blood flow...
  4. doi request reprint Artichoke leave extract for chronic hepatitis C - a pilot study
    R Huber
    Center for Complementary Medicine, University Hospital Freiburg, Freiburg, Germany
    Phytomedicine 16:801-4. 2009
    ..Artichoke leave extracts (ALE) have hepatoprotektive properties and are used by patients with chronic liver disease. Effects in patients with chronic hepatitis C are unclear...
  5. ncbi request reprint In vitro immunoreactivity towards lectin-rich or viscotoxin-rich mistletoe (Viscum album L.) extracts Iscador applied to healthy individuals
    Roman Huber
    Centre for Complementary Medicine Department of Internal Medicine II, University of Freiburg, Germany
    Arzneimittelforschung 56:447-56. 2006
    ..Intriguingly, also in individuals receiving placebo injections immunological alterations were detected during the observation period...
  6. ncbi request reprint Tormentil for active ulcerative colitis: an open-label, dose-escalating study
    Roman Huber
    Department for Internal Medicine II, University Hospital Freiburg, Germany
    J Clin Gastroenterol 41:834-8. 2007
    ..Tormentil extracts (TE) have antioxidative properties and are used as a complementary therapy for chronic inflammatory bowel disease. In individual patients with ulcerative colitis (UC) positive effects have been observed...
  7. doi request reprint Effectiveness of subcutaneous injections of a cartilage preparation in osteoarthritis of the knee--a randomized, placebo controlled phase II study
    Roman Huber
    Department of Environmental Health Sciences, University Hospital Freiburg, Breisacher Str 115B, D 79106 Freiburg, Germany
    Complement Ther Med 18:113-8. 2010
    ..Outcome parameters were the Western Ontario and Mc. Masters University Arthritis Index (WOMAC) scores and the use of concomitant pain medication during a follow up period of 2 months...
  8. doi request reprint Cupping - is it reproducible? Experiments about factors determining the vacuum
    R Huber
    Center for Complementqry Medicine, Department of Environmental Health Sciences, University Hospital Freiburg, Breisacher Str 115B, D 79106 Freiburg, Germany
    Complement Ther Med 19:78-83. 2011
    ..Cupping is a traditional method for treating pain which is investigated nowadays in clinical studies. Because the methods for producing the vacuum vary considerably we tested their reproducibility...
  9. doi request reprint Arnica and stinging nettle for treating burns - a self-experiment
    Roman Huber
    Center for Complementary Medicine, Department of Environmental Health Sciences, University Hospital Freiburg, Germany
    Complement Ther Med 19:276-80. 2011
    ..Because clinical investigations are lacking we wanted to investigate its efficacy in partial thickness burns...
  10. pmc Safety and effects of two mistletoe preparations on production of Interleukin-6 and other immune parameters - a placebo controlled clinical trial in healthy subjects
    Roman Huber
    Uni Zentrum Naturheilkunde, University Medical Center Freiburg, Germany
    BMC Complement Altern Med 11:116. 2011
    ..Since mistletoe preparations are suspected to induce production of potentially tumor promoting cytokines like interleukin (IL)-6, further studies on the immunological effects are of interest...
  11. ncbi request reprint Immunologic effects of mistletoe lectins: a placebo-controlled study in healthy subjects
    Roman Huber
    Center for Complementary Medicine, University Hospital Freiburg, Freiburg, Germany
    J Soc Integr Oncol 4:3-7. 2006
    ..This effect might be related to a stimulation of IL-5 and/or GM-CSF, which was demonstrated ex vivo in vitro. ML resulted in a temporary increase of the granulocyte count, which is probably related to an acute-phase reaction...
  12. ncbi request reprint Effects of a lectin- and a viscotoxin-rich mistletoe preparation on clinical and hematologic parameters: a placebo-controlled evaluation in healthy subjects
    Roman Huber
    Center for Complementary Medicine Department of Internal Medicine II, University Hospital Freiburg, Germany
    J Altern Complement Med 8:857-66. 2002
    ..and a lectin-poor but viscotoxin-rich (Iscador Pini [IP] Weleda Company) mistletoe preparation on clinical and hematologic parameters in healthy subjects...
  13. doi request reprint In vitro antiallergic effects of aqueous fermented preparations from Citrus and Cydonia fruits
    Roman Huber
    Center for Complementary Medicine, Department of Environmental Health Sciences, University Medical Center Freiburg, Freiburg, Germany
    Planta Med 78:334-40. 2012
    ....
  14. doi request reprint Traditionally used Veronica officinalis inhibits proinflammatory mediators via the NF-κB signalling pathway in a human lung cell line
    Carsten Gründemann
    Center for Complementary Medicine, Department of Environmental Health Sciences, University Medical Center Freiburg, Breisacher Str 115B, 79111 Freiburg, Germany
    J Ethnopharmacol 145:118-26. 2013
    ..Extracts from Veronica officinalis L. are traditionally used for the treatment of lung diseases; however, the effective compounds and the mode of action are still unknown...
  15. doi request reprint Inhibition of corneal inflammation following keratoplasty by birch leaf extract
    Katrin Wacker
    University Eye Hospital Freiburg, Killianstr 5, 79106 Freiburg, Germany
    Exp Eye Res 97:24-30. 2012
    ..Accordingly, BPE treatment significantly reduces infiltrating T cells and subsequent corneal opacification following keratoplasty. Our findings suggest BPE as a promising anti-inflammatory drug to treat corneal inflammation...
  16. ncbi request reprint Enhanced in vitro activation of immunocompetent cells in healthy individuals being subcutaneously 'vaccinated' with placebo (physiological saline)
    Reinhild Klein
    Department of Internal Medicine II, University of Tuebingen, Otfried Muller Strasse 10, 72076 Tuebingen, Germany
    Clin Immunol 126:322-31. 2008
    ..Subcutaneous injection of placebo, therefore, enhances immunoreactivity. Psychological aspects, activation of the autonomous nerve system or local activation of mast cells or dendritic cells may be responsible for this phenomenon...
  17. doi request reprint In vitro cytotoxicity of cyclodextrin-bonded birch bark extract
    Anke Hertrampf
    Center for Complementary Medicine, Department of Environmental Health Sciences, University Medical Center Freiburg, Freiburg, Germany
    Planta Med 78:881-9. 2012
    ..STE is far less toxic in hepatocytes. The anticancer potential of STE should be further characterised and also investigated in animal models...
  18. ncbi request reprint Mistletoe treatment induces GM-CSF- and IL-5 production by PBMC and increases blood granulocyte- and eosinophil counts: a placebo controlled randomized study in healthy subjects
    Roman Huber
    Center for Complementary Medicine, University Hospital Freiburg, Breisacher Str 60, D 79106 Freiburg, Germany
    Eur J Med Res 10:411-8. 2005
    ....
  19. doi request reprint Immunomodulatory properties of a lemon-quince preparation (Gencydo®) as an indicator of anti-allergic potency
    Carsten Gründemann
    Center for Complementary Medicine, Department of Environmental Health Sciences, University Medical Center Freiburg, Freiburg, Germany
    Phytomedicine 18:760-8. 2011
    ..Because there are no reports about the mode of action, we investigated the anti-allergic effects of this preparation in vitro by using cell lines and primary cells in various biological and immunological endpoints...
  20. doi request reprint An aqueous birch leaf extract of Betula pendula inhibits the growth and cell division of inflammatory lymphocytes
    Carsten Gründemann
    Center for Complementary Medicine, Department of Environmental Health Sciences, University Medical Centre Freiburg, Breisacher Strasse 115B, Freiburg, Germany
    J Ethnopharmacol 136:444-51. 2011
    ..Leaf extracts of Betula pendula have been traditionally used for the treatment of patients with rheumatoid arthritis (RA) or osteoarthritis...
  21. ncbi request reprint Effects of subtotal fasting on plasmatic coagulation, fibrinolytic status and platelet activation: a controlled pilot study in healthy subjects
    Roman Huber
    Department of Medicine II Gastroenterology, Hepatology, Endocrinology and Infectious Diseases, University Hospital Freiburg, Hugstetter Strasse 55, D 79106 Freiburg, Germany
    Nutr Metab Cardiovasc Dis 15:212-8. 2005
    ..The objective of this study was to determine whether a well-known method of 1-week subtotal fasting affects hemostasis in healthy subjects...
  22. pmc Do plant cyclotides have potential as immunosuppressant peptides?
    Carsten Gründemann
    Center for Complementary Medicine, Department of Environmental Health Sciences, University Medical Center Freiburg, Breisacher Straße 115B, D 79111 Freiburg, Germany
    J Nat Prod 75:167-74. 2012
    ....
  23. ncbi request reprint Experience and attitudes towards CAM--a survey of internal and psychosomatic patients in a German university hospital
    Roman Huber
    Center for Complementary Medicine, University Hospital, Freiburg, Germany
    Altern Ther Health Med 10:32-6. 2004
    ..22), desire to participate in therapeutic decisions (r = 0.29), motivation to change, if recommended, the life style (r = 0.31) and desire for a holistic treatment (r = 0.37)...
  24. pmc Preclinical Evaluation of 4-Methylthiobutyl Isothiocyanate on Liver Cancer and Cancer Stem Cells with Different p53 Status
    Evelyn Lamy
    Department of Environmental Health Sciences, Freiburg University Medical Center, Freiburg, Germany
    PLoS ONE 8:e70846. 2013
    ..Our study could serve for a better understanding of the chemotherapeutic properties of isothiocyanates on human liver-derived cancer cells. ..
  25. ncbi request reprint DDB treatment of patients with chronic hepatitis
    Roman Huber
    University Hospital Freiburg, Department of Medicine II, Freiburg, Germany
    Hepatology 39:1732-3. 2004
    ..In conclusion, the normalization of ALT during DDB treatment does not indicate therapeutic efficacy. In view of the wide use of DDB in patients with chronic liver diseases who participate in clinical studies DDB use should be excluded...
  26. ncbi request reprint Effect of rosiglitazone treatment on plaque inflammation and collagen content in nondiabetic patients: data from a randomized placebo-controlled trial
    Franz Meisner
    Department of Thoracic and Vascular Surgery, University of Ulm, Germany
    Arterioscler Thromb Vasc Biol 26:845-50. 2006
    ....
  27. ncbi request reprint Erythropoietin in cerebrospinal fluid: age-related reference values and relevance in neurological disease
    Karin Widl
    Department of Neurology, University of Ulm, Oberer Eselsberg 45, 89081, Ulm, Germany
    Neurochem Res 32:1163-8. 2007
    ..The establishment of age-related reference values in a large cohort of controls will improve the interpretation of future CSF EPO evaluations in neurological diseases...
  28. ncbi request reprint Bicycle helmet ventilation and comfort angle dependence
    Paul A Brühwiler
    Swiss Federal Laboratories for Materials Testing and Research Empa, Lerchenfeldstrasse 5, 9014 St Gallen, Switzerland
    Eur J Appl Physiol 92:698-701. 2004
    ..Comparisons of skull ventilation at these angles with human subjects strongly supported the headform results...