D Horst

Summary

Affiliation: University of Munich
Country: Germany

Publications

  1. pmc Differential WNT activity in colorectal cancer confers limited tumorigenic potential and is regulated by MAPK signaling
    David Horst
    Department of Medical Oncology, Dana Farber Cancer Institute, Boston, Massachusetts 02215, USA
    Cancer Res 72:1547-56. 2012
  2. pmc SOX2 expression correlates with lymph-node metastases and distant spread in right-sided colon cancer
    Jens Neumann
    Pathologisches Institut, Ludwig Maximilians Universitat Munchen, Munich, Germany
    BMC Cancer 11:518. 2011
  3. pmc LEF-1 and TCF4 expression correlate inversely with survival in colorectal cancer
    Lydia Kriegl
    Department of Pathology, Ludwig Maximilians Universität LMU, Thalkirchnerstr, 36, 80337, Munich, Germany
    J Transl Med 8:123. 2010
  4. pmc CD133 expression is an independent prognostic marker for low survival in colorectal cancer
    D Horst
    Pathologisches Institut der Ludwig Maximilians Universität München, Thalkirchner Str 36, 80337 München, Germany
    Br J Cancer 99:1285-9. 2008
  5. doi request reprint The intratumoral distribution of nuclear beta-catenin is a prognostic marker in colon cancer
    David Horst
    Pathologisches Institut der Ludwig Maximilians Universität, Munich, Germany
    Cancer 115:2063-70. 2009
  6. doi request reprint Comparison of CT colonography, colonoscopy, sigmoidoscopy and faecal occult blood tests for the detection of advanced adenoma in an average risk population
    A Graser
    Department of Clinical Radiology, University of Munich, Klinikum Grosshadern, Munich, Germany
    Gut 58:241-8. 2009
  7. doi request reprint [Plasticity of WNT signaling activity in colorectal cancer]
    D Horst
    Pathologisches Institut, Ludwig Maximilians Universitat Munchen, Thalkirchner Str 36, 80337 München
    Pathologe 33:194-7. 2012

Detail Information

Publications7

  1. pmc Differential WNT activity in colorectal cancer confers limited tumorigenic potential and is regulated by MAPK signaling
    David Horst
    Department of Medical Oncology, Dana Farber Cancer Institute, Boston, Massachusetts 02215, USA
    Cancer Res 72:1547-56. 2012
    ..Furthermore, they suggest that MAPK signaling is a critical modifier of intratumoral heterogeneity that contributes significantly to determining the impact of WNT activity on stemness phenotypes in colon cancer cells...
  2. pmc SOX2 expression correlates with lymph-node metastases and distant spread in right-sided colon cancer
    Jens Neumann
    Pathologisches Institut, Ludwig Maximilians Universitat Munchen, Munich, Germany
    BMC Cancer 11:518. 2011
    ....
  3. pmc LEF-1 and TCF4 expression correlate inversely with survival in colorectal cancer
    Lydia Kriegl
    Department of Pathology, Ludwig Maximilians Universität LMU, Thalkirchnerstr, 36, 80337, Munich, Germany
    J Transl Med 8:123. 2010
    ..In this study we investigated the expression of β-Catenin, LEF1 and TCF4 in colorectal carcinomas and their prognostic significance...
  4. pmc CD133 expression is an independent prognostic marker for low survival in colorectal cancer
    D Horst
    Pathologisches Institut der Ludwig Maximilians Universität München, Thalkirchner Str 36, 80337 München, Germany
    Br J Cancer 99:1285-9. 2008
    ..Our results indicate that in colorectal cancer, the CD133+ tumour cells can be detected by immunohistochemistry, which facilitates their further characterisation in situ...
  5. doi request reprint The intratumoral distribution of nuclear beta-catenin is a prognostic marker in colon cancer
    David Horst
    Pathologisches Institut der Ludwig Maximilians Universität, Munich, Germany
    Cancer 115:2063-70. 2009
    ..Herein, the authors investigated whether the intratumoral distribution of nuclear beta-catenin can serve as a prognostic marker for survival and tumor progression of stage IIA colon cancer patients...
  6. doi request reprint Comparison of CT colonography, colonoscopy, sigmoidoscopy and faecal occult blood tests for the detection of advanced adenoma in an average risk population
    A Graser
    Department of Clinical Radiology, University of Munich, Klinikum Grosshadern, Munich, Germany
    Gut 58:241-8. 2009
    ....
  7. doi request reprint [Plasticity of WNT signaling activity in colorectal cancer]
    D Horst
    Pathologisches Institut, Ludwig Maximilians Universitat Munchen, Thalkirchner Str 36, 80337 München
    Pathologe 33:194-7. 2012
    ..Furthermore, WNT/β-Catenin activity in colon cancer cells can be modulated by MAPK signaling thus revealing a means of how other signaling pathways contribute to WNT signaling plasticity in colon cancer...