Stefan Honing

Summary

Affiliation: University of Cologne
Country: Germany

Publications

  1. ncbi request reprint Phosphatidylinositol-(4,5)-bisphosphate regulates sorting signal recognition by the clathrin-associated adaptor complex AP2
    Stefan Honing
    Institute for Biochemistry II, University of Gottingen, Heinrich Düker Weg 12, 37073 Gottingen, Germany
    Mol Cell 18:519-31. 2005
  2. doi request reprint AP-1 and AP-3 mediate sorting of melanosomal and lysosomal membrane proteins into distinct post-Golgi trafficking pathways
    Björn Chapuy
    Institute of Biochemistry II, Department of Hematology and Oncology, University of Gottingen, Heinrich Düker Weg 12, 37073 Gottingen, Germany
    Traffic 9:1157-72. 2008
  3. pmc Phosphorylation of the AP2 mu subunit by AAK1 mediates high affinity binding to membrane protein sorting signals
    Doris Ricotta
    Institute for Biochemistry II, University of Gottingen, 37073 Gottingen, Germany
    J Cell Biol 156:791-5. 2002
  4. pmc TIP47 functions in the biogenesis of lipid droplets
    Anna V Bulankina
    Institute for Biochemistry II, University of Gottingen, 37073 Gottingen, Germany
    J Cell Biol 185:641-55. 2009
  5. ncbi request reprint The tyrosine motifs of Lamp 1 and LAP determine their direct and indirect targetting to lysosomes
    Stefanie Obermuller
    Institute for Biochemistry II, University of Gottingen, Heinrich Düker Weg 12, 37073 Gottingen, Germany
    J Cell Sci 115:185-94. 2002
  6. ncbi request reprint Beta-arrestin binding to CC chemokine receptor 5 requires multiple C-terminal receptor phosphorylation sites and involves a conserved Asp-Arg-Tyr sequence motif
    Friederike Huttenrauch
    Department of Immunology, University of Gottingen, Kreuzbergring 57, 37075 Gottingen, Germany
    J Biol Chem 277:30769-77. 2002
  7. ncbi request reprint Granzyme-mediated cytotoxicity does not involve the mannose 6-phosphate receptors on target cells
    Ralf Dressel
    Division of Immunogenetics, University of Gottingen, Heinrich Düker Weg 12, 37073 Gottingen, Germany
    J Biol Chem 279:20200-10. 2004
  8. pmc Deficiency of UDP-galactose:N-acetylglucosamine beta-1,4-galactosyltransferase I causes the congenital disorder of glycosylation type IId
    Bengt Hansske
    Abteilung Biochemie II, Georg August Universitat Gottingen, Heinrich Düker Weg 12, D 37073 Gottingen, Germany
    J Clin Invest 109:725-33. 2002
  9. ncbi request reprint Arabidopsis mu A-adaptin interacts with the tyrosine motif of the vacuolar sorting receptor VSR-PS1
    Nicole Happel
    Institute for Biochemistry and Molecular Cell Biology, University of Gottingen, D 37073 Gottingen, Germany
    Plant J 37:678-93. 2004

Collaborators

  • Srikumar M Raja
  • Ralf Dressel
  • Markus G Rudolph
  • Volker Haucke
  • Fang Tsyr Lin
  • K N Burger
  • D J Owen
  • Kurt von Figura
  • Anna V Bulankina
  • Dirk Wenzel
  • Björn Chapuy
  • Nicole Happel
  • Stefanie Obermuller
  • Friederike Huttenrauch
  • Doris Ricotta
  • Bengt Hansske
  • Julia G Wittmann
  • Anke Deggerich
  • Kudzai Mutenda
  • Chris Mühlhausen
  • Ritva Tikkanen
  • David G Robinson
  • Susanne E H Holstein
  • Jean Marc Neuhaus
  • Nadine Paris
  • Eric G Berger
  • Martin Hasilik
  • Martin Oppermann
  • Sandra L Schmid
  • Torben Lübke
  • Christian Thiel
  • Georg F Hoffmann
  • Christina Kiecke
  • Sean D Conner
  • Peter H Heidemann
  • Antje Nitzki
  • Verena Peters
  • Christian Korner

Detail Information

Publications9

  1. ncbi request reprint Phosphatidylinositol-(4,5)-bisphosphate regulates sorting signal recognition by the clathrin-associated adaptor complex AP2
    Stefan Honing
    Institute for Biochemistry II, University of Gottingen, Heinrich Düker Weg 12, 37073 Gottingen, Germany
    Mol Cell 18:519-31. 2005
    ..The binding of AP2 to acidic-dileucine motifs occurs at a different site from Yxxvarphi binding and is not enhanced by mu2Thr156 phosphorylation...
  2. doi request reprint AP-1 and AP-3 mediate sorting of melanosomal and lysosomal membrane proteins into distinct post-Golgi trafficking pathways
    Björn Chapuy
    Institute of Biochemistry II, Department of Hematology and Oncology, University of Gottingen, Heinrich Düker Weg 12, 37073 Gottingen, Germany
    Traffic 9:1157-72. 2008
    ....
  3. pmc Phosphorylation of the AP2 mu subunit by AAK1 mediates high affinity binding to membrane protein sorting signals
    Doris Ricotta
    Institute for Biochemistry II, University of Gottingen, 37073 Gottingen, Germany
    J Cell Biol 156:791-5. 2002
    ..We propose that phosphorylation of the AP2 mu 2 subunit by AAK1 ensures high affinity binding of AP2 to sorting signals of cargo membrane proteins during the initial steps of receptor-mediated endocytosis...
  4. pmc TIP47 functions in the biogenesis of lipid droplets
    Anna V Bulankina
    Institute for Biochemistry II, University of Gottingen, 37073 Gottingen, Germany
    J Cell Biol 185:641-55. 2009
    ..Suppression of TIP47 blocked LD maturation and decreased the incorporation of triacylglycerol into LDs. We conclude that TIP47 functions in the biogenesis of LDs...
  5. ncbi request reprint The tyrosine motifs of Lamp 1 and LAP determine their direct and indirect targetting to lysosomes
    Stefanie Obermuller
    Institute for Biochemistry II, University of Gottingen, Heinrich Düker Weg 12, 37073 Gottingen, Germany
    J Cell Sci 115:185-94. 2002
    ..In conclusion, the residues +2 and +3 of the tyrosine motifs determine the sorting of Lamp 1 and LAP in endosomes, mediating either the direct or the indirect pathway to lysosomes...
  6. ncbi request reprint Beta-arrestin binding to CC chemokine receptor 5 requires multiple C-terminal receptor phosphorylation sites and involves a conserved Asp-Arg-Tyr sequence motif
    Friederike Huttenrauch
    Department of Immunology, University of Gottingen, Kreuzbergring 57, 37075 Gottingen, Germany
    J Biol Chem 277:30769-77. 2002
    ..These results suggest that a conserved sequence motif within the second intracellular loop of CCR5 that is known to be involved in G protein activation plays a significant role in beta-arrestin binding to CCR5...
  7. ncbi request reprint Granzyme-mediated cytotoxicity does not involve the mannose 6-phosphate receptors on target cells
    Ralf Dressel
    Division of Immunogenetics, University of Gottingen, Heinrich Düker Weg 12, 37073 Gottingen, Germany
    J Biol Chem 279:20200-10. 2004
    ..In conclusion, these results strongly argue against an Mpr300- or Mpr46-dependent pathway of granzyme-mediated killing and provide new insight in the internalization of monomeric and complexed granzyme B...
  8. pmc Deficiency of UDP-galactose:N-acetylglucosamine beta-1,4-galactosyltransferase I causes the congenital disorder of glycosylation type IId
    Bengt Hansske
    Abteilung Biochemie II, Georg August Universitat Gottingen, Heinrich Düker Weg 12, D 37073 Gottingen, Germany
    J Clin Invest 109:725-33. 2002
    ..The patient was homozygous and his parents heterozygous for this mutation. Expression of a corresponding mutant cDNA in COS-7 cells led to the synthesis of a truncated, inactive polypeptide, which localized to the endoplasmic reticulum...
  9. ncbi request reprint Arabidopsis mu A-adaptin interacts with the tyrosine motif of the vacuolar sorting receptor VSR-PS1
    Nicole Happel
    Institute for Biochemistry and Molecular Cell Biology, University of Gottingen, D 37073 Gottingen, Germany
    Plant J 37:678-93. 2004
    ..The trans-Golgi localization of the mu A-adaptin strongly suggests its involvement in Golgi- to vacuole-trafficking events...