Kristian Holtkamp

Summary

Affiliation: University Hospital
Country: Germany

Publications

  1. ncbi request reprint High prevalence of increased trisialotransferrin concentrations in patients with anorexia nervosa: implications for determination of carbohydrate-deficient transferrin
    Torsten Arndt
    Bioscientia Institut fuer Medizinische Diagnostik GmbH, D 55218 Ingelheim, Germany
    Clin Chim Acta 379:150-3. 2007
  2. doi request reprint Serum levels of S100B are decreased in chronic starvation and normalize with weight gain
    Kristian Holtkamp
    Department of Child and Adolescent Psychiatry and Psychotherapy, RWTH Aachen University, Aachen, Germany
    J Neural Transm 115:937-40. 2008
  3. ncbi request reprint Depression, anxiety, and obsessionality in long-term recovered patients with adolescent-onset anorexia nervosa
    K Holtkamp
    Department of Child and Adolescent Psychiatry and Psychotherapy, Technical University of Aachen, Neuenhofer Weg 21, 52074 Aachen, Germany
    Eur Child Adolesc Psychiatry 14:106-10. 2005
  4. ncbi request reprint The contribution of anxiety and food restriction on physical activity levels in acute anorexia nervosa
    Kristian Holtkamp
    Department of Child and Adolescent Psychiatry and Psychotherapy, Technical University Aachen, Neuenhofer Weg 21, D 52074 Aachen, Germany
    Int J Eat Disord 36:163-71. 2004
  5. ncbi request reprint High serum leptin levels subsequent to weight gain predict renewed weight loss in patients with anorexia nervosa
    K Holtkamp
    Department of Child and Adolescent Psychiatry and Psychotherapy, Aachen University, Neuenhofer Weg 21, D 52074 Aachen, Germany
    Psychoneuroendocrinology 29:791-7. 2004
  6. ncbi request reprint Overweight and obesity in children with Attention-Deficit/Hyperactivity Disorder
    K Holtkamp
    Department of Child and Adolescent Psychiatry and Psychotherapy, Technical University of Aachen, Germany
    Int J Obes Relat Metab Disord 28:685-9. 2004
  7. ncbi request reprint Physical activity and restlessness correlate with leptin levels in patients with adolescent anorexia nervosa
    Kristian Holtkamp
    Department of Child and Adolescent Psychiatry and Psychotherapy, RWTH Aachen University, Aachen, Germany
    Biol Psychiatry 60:311-3. 2006
  8. ncbi request reprint A retrospective study of SSRI treatment in adolescent anorexia nervosa: insufficient evidence for efficacy
    K Holtkamp
    Department of Child and Adolescent Psychiatry and Psychotherapy, University Clinic of Aachen, Germany
    J Psychiatr Res 39:303-10. 2005
  9. doi request reprint Weight gain in children and adolescents during 45 weeks treatment with clozapine, olanzapine and risperidone
    Christian Fleischhaker
    Department of Child and Adolescent Psychiatry and Psychotherapy, University of Freiburg, Hauptstrasse 8, 79104, Freiburg, Germany
    J Neural Transm 115:1599-608. 2008
  10. ncbi request reprint Elevated physical activity and low leptin levels co-occur in patients with anorexia nervosa
    Kristian Holtkamp
    Department of Child and Adolescent Psychiatry and Psychotherapy, Aachen University, D 52074 Aachen, Germany
    J Clin Endocrinol Metab 88:5169-74. 2003

Detail Information

Publications27

  1. ncbi request reprint High prevalence of increased trisialotransferrin concentrations in patients with anorexia nervosa: implications for determination of carbohydrate-deficient transferrin
    Torsten Arndt
    Bioscientia Institut fuer Medizinische Diagnostik GmbH, D 55218 Ingelheim, Germany
    Clin Chim Acta 379:150-3. 2007
    ..We tested whether previous findings of false-positive CDT results for anorexia nervosa patients have been due to invalid CDT analysis methods or anorexia nervosa by itself...
  2. doi request reprint Serum levels of S100B are decreased in chronic starvation and normalize with weight gain
    Kristian Holtkamp
    Department of Child and Adolescent Psychiatry and Psychotherapy, RWTH Aachen University, Aachen, Germany
    J Neural Transm 115:937-40. 2008
    ..We found that nutritional status was an important factor influencing serum levels of S100B...
  3. ncbi request reprint Depression, anxiety, and obsessionality in long-term recovered patients with adolescent-onset anorexia nervosa
    K Holtkamp
    Department of Child and Adolescent Psychiatry and Psychotherapy, Technical University of Aachen, Neuenhofer Weg 21, 52074 Aachen, Germany
    Eur Child Adolesc Psychiatry 14:106-10. 2005
    ..In conclusion, depressive, anxious, and obsessive-compulsive symptoms may be personality traits in subjects with former adolescent anorexia nervosa...
  4. ncbi request reprint The contribution of anxiety and food restriction on physical activity levels in acute anorexia nervosa
    Kristian Holtkamp
    Department of Child and Adolescent Psychiatry and Psychotherapy, Technical University Aachen, Neuenhofer Weg 21, D 52074 Aachen, Germany
    Int J Eat Disord 36:163-71. 2004
    ..Interconnections among caloric restriction, psychopathology, and physical activity in humans with AN are poorly investigated...
  5. ncbi request reprint High serum leptin levels subsequent to weight gain predict renewed weight loss in patients with anorexia nervosa
    K Holtkamp
    Department of Child and Adolescent Psychiatry and Psychotherapy, Aachen University, Neuenhofer Weg 21, D 52074 Aachen, Germany
    Psychoneuroendocrinology 29:791-7. 2004
    ..In conclusion, high serum leptin levels at discharge from inpatient treatment may indicate a risk for renewed weight loss and an unfavorable 1 yr outcome in AN...
  6. ncbi request reprint Overweight and obesity in children with Attention-Deficit/Hyperactivity Disorder
    K Holtkamp
    Department of Child and Adolescent Psychiatry and Psychotherapy, Technical University of Aachen, Germany
    Int J Obes Relat Metab Disord 28:685-9. 2004
    ..The aim of our study was to assess if the prevalence of overweight and obesity is lower in a population of boys with ADHD in comparison with the German healthy male reference population of the same age...
  7. ncbi request reprint Physical activity and restlessness correlate with leptin levels in patients with adolescent anorexia nervosa
    Kristian Holtkamp
    Department of Child and Adolescent Psychiatry and Psychotherapy, RWTH Aachen University, Aachen, Germany
    Biol Psychiatry 60:311-3. 2006
    ..Leptin ameliorates anxiety-related movement in ob/ob mice. In this study, we assessed the relationship between leptin and qualities of physical activity and restlessness in acute anorexia nervosa (AN)...
  8. ncbi request reprint A retrospective study of SSRI treatment in adolescent anorexia nervosa: insufficient evidence for efficacy
    K Holtkamp
    Department of Child and Adolescent Psychiatry and Psychotherapy, University Clinic of Aachen, Germany
    J Psychiatr Res 39:303-10. 2005
    ..Clinicians should be chary in prescribing SSRI in adolescent AN unless randomized controlled trials have proofed the benefit of these drugs...
  9. doi request reprint Weight gain in children and adolescents during 45 weeks treatment with clozapine, olanzapine and risperidone
    Christian Fleischhaker
    Department of Child and Adolescent Psychiatry and Psychotherapy, University of Freiburg, Hauptstrasse 8, 79104, Freiburg, Germany
    J Neural Transm 115:1599-608. 2008
    ..Clozapine and risperidone are associated with a less marked weight gain in children and adolescents but also much higher than that expected in adults. These differences may affect compliance with medication and health risk...
  10. ncbi request reprint Elevated physical activity and low leptin levels co-occur in patients with anorexia nervosa
    Kristian Holtkamp
    Department of Child and Adolescent Psychiatry and Psychotherapy, Aachen University, D 52074 Aachen, Germany
    J Clin Endocrinol Metab 88:5169-74. 2003
    ..003). Our results suggest that, similar to semistarvation-induced hyperactivity in rats, hypoleptinemia in patients with AN may be one important factor underlying the excessive physical activity...
  11. doi request reprint Leptin-mediated neuroendocrine alterations in anorexia nervosa: somatic and behavioral implications
    Timo D Müller
    Department of Child and Adolescent Psychiatry and Psychotherapy, University of Duisburg Essen, Virchowstrasse 174, 45147 Essen, Germany
    Child Adolesc Psychiatr Clin N Am 18:117-29. 2009
    ..During therapeutically induced weight gain, leptin levels can intermittently increase above normal concentrations. This hyperleptinemia could predispose to renewed weight loss...
  12. ncbi request reprint Improvement of nutritional status as assessed by multifrequency BIA during 15 weeks of refeeding in adolescent girls with anorexia nervosa
    Claudia Mika
    Department of Child and Adolescent Psychiatry and Psychotherapy, Technical University of Aachen, Aachen, Germany
    J Nutr 134:3026-30. 2004
    ..An individually determined and controlled hyperenergetic diet as part of a multidimensional, interdisciplinary treatment program for eating disorders seems to quickly improve the nutritional status of AN patients...
  13. doi request reprint Familiality and molecular genetics of attention networks in ADHD
    Kerstin Konrad
    Child Neuropsychology Section, Department of Child and Adolescent Psychiatry of RTWH Aachen, Aachen, Germany
    Am J Med Genet B Neuropsychiatr Genet 153:148-58. 2010
    ....
  14. doi request reprint Differential patterns of disordered eating in subjects with ADHD and overweight
    Christine Wilhelm
    Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, University Clinics, RWTH Aachen University, Aachen, Germany
    World J Biol Psychiatry 12:118-23. 2011
    ..Despite growing evidence for an association between overweight and attention-deficit/hyperactivity disorder (ADHD), still little is known about the mechanisms underlying this relationship...
  15. ncbi request reprint [Adolescent eating disorders]
    Beate Herpertz-Dahlmann
    Klinik fur Kinder und Jugendpsychiatrie und psychotherapie, Universitatsklinikum Aachen
    Prax Kinderpsychol Kinderpsychiatr 54:248-67. 2005
    ..g. weight rehabilitation, nutritional counselling, individual and family psychotherapy, and treatment of comorbid psychiatric disorders...
  16. doi request reprint [Neuropsychological performance in anorexia and bulimia nervosa]
    Katharina Bühren
    Klinik fur Kinder und Jugendpsychiatrie und psychotherapie, Universitatsklinikum Aachen
    Z Kinder Jugendpsychiatr Psychother 36:377-86; quiz 387-8. 2008
    ..The following review describes in detail the neuropsychological impairments in eating disorders, potential factors influencing cognitive performance, and resulting implications for clinical every day life...
  17. doi request reprint [Schizophreniform symptoms in Chorea Minor--case report and literature review]
    Jennifer A Vloet
    Klinik fur Kinder und Jugendpsychiatrie und psychotherapie, Universitätsklinikum der RWTH Aachen, Aachen
    Z Kinder Jugendpsychiatr Psychother 38:161-8. 2010
    ..The negative symptoms may result from disturbances of the prefrontal cortex impaired by basal-ganglia dysfunction...
  18. ncbi request reprint The effect of therapeutically induced weight gain on plasma leptin levels in patients with anorexia nervosa
    K Holtkamp
    Department of Child and Adolescent Psychiatry and Psychotherapy, Aachen University, Neuenhofer Weg 21, D 52074, Aachen, Germany
    J Psychiatr Res 37:165-9. 2003
    ..001) and lg10 leptin level at admission (P=0.002). In conclusion, we confirmed weight gain induced hyperleptinemia in AN. Further research is required to assess if this phenomenon contributes to renewed weight loss...
  19. ncbi request reprint Reproductive function during weight gain in anorexia nervosa. Leptin represents a metabolic gate to gonadotropin secretion
    K Holtkamp
    Department of Child and Adolescent Psychiatry, Technical University of Aachen, Germany
    J Neural Transm 110:427-35. 2003
    ..Once this is exceeded other biological mechanisms seem to be important for the complete recovery of the reproductive function and the resumption of menses...
  20. ncbi request reprint Clinical drug monitoring in child and adolescent psychiatry: side effects of atypical neuroleptics
    Christian Fleischhaker
    Department of Child and Adolescent Psychiatry and Psychotherapy, Albert Ludwigs University Freiburg, Hauptstrasse 8, 79104 Freiburg, Germany
    J Child Adolesc Psychopharmacol 16:308-16. 2006
    ..The aim of this study was to improve and evaluate the practibility of a method for the assessment of drug-associated side effects, and we implemented a clinical drug monitoring for atypical neuroleptics...
  21. ncbi request reprint The influence of sertraline on attention and verbal memory in children and adolescents with anxiety disorders
    Thomas Gunther
    Department of Child and Adolescent Psychiatry, Aachen University, Aachen, Germany
    J Child Adolesc Psychopharmacol 15:608-18. 2005
    ..Thus, the cognitive side effects of sertraline seemed to differ slightly between pediatric patients and those described in adult patient groups, should, therefore, be carefully assessed...
  22. ncbi request reprint Gastric dilatation in a girl with former obesity and atypical anorexia nervosa
    Kristian Holtkamp
    Department of Child and Adolescent Psychiatry and Psychotherapy, Technical University Aachen, Germany
    Int J Eat Disord 32:372-6. 2002
    ..This case report describes a 16 year-old girl of normal weight with acute gastric dilatation due to binge eating habits...
  23. ncbi request reprint Methylphenidate-related growth impairment
    Kristian Holtkamp
    Department of Child and Adolescent Psychiatry and Psychotherapy, Technical University, Aachen, Germany
    J Child Adolesc Psychopharmacol 12:55-61. 2002
    ..We found that the determination of growth velocity was a sensitive marker for the evaluation of growth impairment in our patient...
  24. ncbi request reprint The role of leptin in anorexia nervosa: clinical implications
    J Hebebrand
    Department of Child and Adolescent Psychiatry and Psychotherapy, University of Duisburg Essen, Essen, Germany
    Mol Psychiatry 12:23-35. 2007
    ..The fact that hypoleptinaemia can induce hyperactivity in a rat model for AN has led to a series of studies in AN patients, which support the notion that application of leptin to severely hyperactive patients might prove beneficial...
  25. ncbi request reprint Verbal memory and aspects of attentional control in children and adolescents with anxiety disorders or depressive disorders
    Thomas Gunther
    Department of Child and Adolescent Psychiatry, University Hospital of Aachen, Neuenhofer Weg 21, D 52074 Aachen, Germany
    J Affect Disord 82:265-9. 2004
    ..The aim was to examine basic performance on attention and memory tasks in treatment-naive children and adolescents with anxiety disorder or depressive disorder and in healthy subjects under drug-free conditions...
  26. ncbi request reprint A 2-year prospective study of bone metabolism and bone mineral density in adolescents with anorexia nervosa
    C Mika
    Department of Child and Adolescent Psychiatry and Psychotherapy, University Clinic, Technical University, Aachen, Germany
    J Neural Transm 114:1611-8. 2007
    ..Since we could not observe a "catch up" effect in BMD of girls with AN in a 2-year follow-up, BMD of these patients needs to be carefully monitored until adulthood to detect early osteoporosis...
  27. ncbi request reprint Weight gain associated with clozapine, olanzapine and risperidone in children and adolescents
    C Fleischhaker
    Department of Child and Adolescent Psychiatry and Psychotherapy, Albert Ludwig University, Freiburg, Germany
    J Neural Transm 114:273-80. 2007
    ..8 kg, SD = 1.3) and clozapine (mean = 2.5 kg, SD = 2.9) groups. Olanzapine and risperidone, but not clozapine, caused a disproportionately higher weight gain in children and adolescents in comparison to adults...