F Hoffmann

Summary

Affiliation: University of Munich
Country: Germany

Publications

  1. pmc Expression, regulation and clinical significance of soluble and membrane CD14 receptors in pediatric inflammatory lung diseases
    Veronica Marcos
    Children s Hospital of the Ludwig Maximilians University, Munich, Germany
    Respir Res 11:32. 2010
  2. ncbi request reprint [Feverish infant]
    F Hoffmann
    Kinderklinik und Kinderpoliklinik im Dr von Haunerschen Kinderspital der LMU Müchen, Muchen
    MMW Fortschr Med 149:46-7. 2007
  3. pmc Home-based subcutaneous immunoglobulin G replacement therapy under real-life conditions in children and adults with antibody deficiency
    F Hoffmann
    University Children s Hospital, Paediatric Infectious Diseases and Immunology, Ludwig Maximilians University, Munich, Germany
    Eur J Med Res 15:238-45. 2010
  4. ncbi request reprint Identification of a novel mevalonate kinase gene mutation in combination with the common MVK V377I substitution and the low-penetrance TNFRSF1A R92Q mutation
    Florian Hoffmann
    Department of Infectious Diseases and Immunology, Children s Hospital, University of Munich, Germany
    Eur J Hum Genet 13:510-2. 2005
  5. ncbi request reprint Comparison of two antiretroviral triple combinations including the protease inhibitor indinavir in children infected with human immunodeficiency virus
    U Wintergerst
    Children s Hospital, Ludwig Maximilians University Munich, Germany
    Pediatr Infect Dis J 17:495-9. 1998
  6. doi request reprint Antiviral efficacy, tolerability and pharmacokinetics of efavirenz in an unselected cohort of HIV-infected children
    U Wintergerst
    Department of Immunodeficiency Diseases, Childrens Hospital of the Ludwig Maximilians University, Munich, Germany
    J Antimicrob Chemother 61:1336-9. 2008
  7. ncbi request reprint Long-term pharmacokinetics of amprenavir in combination with delavirdine in HIV-infected children
    C Engelhorn
    Department of Immunodeficiency Diseases, Childrens Hospital of the Ludwig Maximilians University, Munich, Germany
    AIDS 18:1473-5. 2004
  8. doi request reprint Successful long-term correction of autosomal recessive hyper-IgE syndrome due to DOCK8 deficiency by hematopoietic stem cell transplantation
    T C Bittner
    Departments for Pediatric Hematology Oncology and Infection Immunity, Dr von Haunersches Kinderspital, Ludwig Maximilians University, Lindwurmstrasse 4, Munich, Germany
    Klin Padiatr 222:351-5. 2010
  9. ncbi request reprint Comparison of ritonavir plus saquinavir- and nelfinavir plus saquinavir-containing regimens as salvage therapy in children with human immunodeficiency type 1 infection
    F Hoffmann
    Children s Hospital of the Ludwig Maximilians University Munich, Germany
    Pediatr Infect Dis J 19:47-51. 2000
  10. ncbi request reprint Infiltrated neutrophils acquire novel chemokine receptor expression and chemokine responsiveness in chronic inflammatory lung diseases
    Dominik Hartl
    Childrens Hospital, Ludwig Maximilians University, Munich, Germany
    J Immunol 181:8053-67. 2008

Collaborators

Detail Information

Publications18

  1. pmc Expression, regulation and clinical significance of soluble and membrane CD14 receptors in pediatric inflammatory lung diseases
    Veronica Marcos
    Children s Hospital of the Ludwig Maximilians University, Munich, Germany
    Respir Res 11:32. 2010
    ..Therefore, we examined the expression, regulation and significance of sCD14 and mCD14 in pediatric lung diseases...
  2. ncbi request reprint [Feverish infant]
    F Hoffmann
    Kinderklinik und Kinderpoliklinik im Dr von Haunerschen Kinderspital der LMU Müchen, Muchen
    MMW Fortschr Med 149:46-7. 2007
  3. pmc Home-based subcutaneous immunoglobulin G replacement therapy under real-life conditions in children and adults with antibody deficiency
    F Hoffmann
    University Children s Hospital, Paediatric Infectious Diseases and Immunology, Ludwig Maximilians University, Munich, Germany
    Eur J Med Res 15:238-45. 2010
    ..Subcutaneous immunoglobulin (SCIG) therapy is an alternative to intravenous immunoglobulin (IVIG) therapy...
  4. ncbi request reprint Identification of a novel mevalonate kinase gene mutation in combination with the common MVK V377I substitution and the low-penetrance TNFRSF1A R92Q mutation
    Florian Hoffmann
    Department of Infectious Diseases and Immunology, Children s Hospital, University of Munich, Germany
    Eur J Hum Genet 13:510-2. 2005
    ..The girl was also heterozygous for the TNFRSF1A R92Q low-penetrance mutation, which may have significant proinflammatory effects. However, at the time of presentation, the patient had no TRAPS-associated symptoms...
  5. ncbi request reprint Comparison of two antiretroviral triple combinations including the protease inhibitor indinavir in children infected with human immunodeficiency virus
    U Wintergerst
    Children s Hospital, Ludwig Maximilians University Munich, Germany
    Pediatr Infect Dis J 17:495-9. 1998
    ..The effects of two antiretroviral triple combinations including the protease inhibitor indinavir on the surrogate markers, viral load and CD4 cells were evaluated...
  6. doi request reprint Antiviral efficacy, tolerability and pharmacokinetics of efavirenz in an unselected cohort of HIV-infected children
    U Wintergerst
    Department of Immunodeficiency Diseases, Childrens Hospital of the Ludwig Maximilians University, Munich, Germany
    J Antimicrob Chemother 61:1336-9. 2008
    ..To obtain data on the pharmacokinetics of efavirenz in children in clinical practice...
  7. ncbi request reprint Long-term pharmacokinetics of amprenavir in combination with delavirdine in HIV-infected children
    C Engelhorn
    Department of Immunodeficiency Diseases, Childrens Hospital of the Ludwig Maximilians University, Munich, Germany
    AIDS 18:1473-5. 2004
    ..5 log after 18 months. Delavirdine boosted amprenavir trough levels more than 10-fold, and delavirdine trough levels remained i several fold above susceptible HIV strains...
  8. doi request reprint Successful long-term correction of autosomal recessive hyper-IgE syndrome due to DOCK8 deficiency by hematopoietic stem cell transplantation
    T C Bittner
    Departments for Pediatric Hematology Oncology and Infection Immunity, Dr von Haunersches Kinderspital, Ludwig Maximilians University, Lindwurmstrasse 4, Munich, Germany
    Klin Padiatr 222:351-5. 2010
    ..This argues for early curative therapeutic approaches, supported by this report of successful long-term outcome after HSCT...
  9. ncbi request reprint Comparison of ritonavir plus saquinavir- and nelfinavir plus saquinavir-containing regimens as salvage therapy in children with human immunodeficiency type 1 infection
    F Hoffmann
    Children s Hospital of the Ludwig Maximilians University Munich, Germany
    Pediatr Infect Dis J 19:47-51. 2000
    ....
  10. ncbi request reprint Infiltrated neutrophils acquire novel chemokine receptor expression and chemokine responsiveness in chronic inflammatory lung diseases
    Dominik Hartl
    Childrens Hospital, Ludwig Maximilians University, Munich, Germany
    J Immunol 181:8053-67. 2008
    ....
  11. doi request reprint Atrial natriuretic peptide protects against histamine-induced endothelial barrier dysfunction in vivo
    Robert Fürst
    Department of Pharmacy, Pharmaceutical Biology, University of Munich, Butenandtstr 5 13, 81377 Munich, Germany
    Mol Pharmacol 74:1-8. 2008
    ..Thus, our study highlights ANP as an interesting pharmacological compound opening new therapeutic options for preventing endothelial leakage...
  12. ncbi request reprint Dysregulation of innate immune receptors on neutrophils in chronic granulomatous disease
    Dominik Hartl
    Children s Hospital of the Ludwig Maximilians University, Munich, Germany
    J Allergy Clin Immunol 121:375-382.e9. 2008
    ....
  13. ncbi request reprint Molecular analysis of the MVK and TNFRSF1A genes in patients with a clinical presentation typical of the hyperimmunoglobulinemia D with periodic fever syndrome: a low-penetrance TNFRSF1A variant in a heterozygous MVK carrier possibly influences the phenot
    Silvia Stojanov
    Department of Infectious Diseases Immunology, Children s Hospital, University of Munich, Munich, Germany
    Arthritis Rheum 50:1951-8. 2004
    ....
  14. ncbi request reprint No indication for a defect in toll-like receptor signaling in patients with hyper-IgE syndrome
    E D Renner
    University Children s Hospital, Dr von Haunersches Kinderspital, Ludwig Maximilians University, Munich, Germany
    J Clin Immunol 25:321-8. 2005
    ..In summary, our data confirmed an imbalance in T cell responses of patients with hyper-IgE syndrome as previously described but showed no indication for an underlying defect in toll-like receptor signaling...
  15. ncbi request reprint Effect of antiretroviral triple combinations including the protease inhibitor nelfinavir in heavily pretreated children with HIV-1 infection
    F Hoffmann
    Children s Hospital of the Ludwig Maximilians University, Munich, Germany
    Eur J Med Res 7:330-4. 2002
    ..In this retrospective study the effect of antiretroviral triple therapy including the protease-inhibitor nelfinavir (NFV) on CD4-cells and viral load (VL) in heavily pretreated HIV-infected children was evaluated...
  16. doi request reprint Transgene expression of transfected supercoiled plasmid DNA concatemers in mammalian cells
    Christof Maucksch
    Department of Pediatrics, Ludwig Maximilians University, Munich, Germany
    J Gene Med 11:444-53. 2009
    ..Supercoiled topology of transfected plasmid DNA (pDNA) is critical for transgene expression in mammalian cells. In the present study, we analysed transgene expression of transfected supercoiled pDNA concatemers...
  17. ncbi request reprint Cytokine profile in PFAPA syndrome suggests continuous inflammation and reduced anti-inflammatory response
    Silvia Stojanov
    Department of Infectious Diseases and Immunology, Children s Hospital, University of Munich, Germany
    Eur Cytokine Netw 17:90-7. 2006
    ....
  18. ncbi request reprint Interaction of polyamine gene vectors with RNA leads to the dissociation of plasmid DNA-carrier complexes
    Stephanie Huth
    Department of Pediatrics, Ludwig Maximilians University, 80337 Munich, Germany
    J Gene Med 8:1416-24. 2006
    ..Since RNA is present in the cytoplasm at high concentrations and due to its structural similarity to DNA, we were interested in its conceivable interaction with polyamine gene vectors...