M J Hilz

Summary

Affiliation: University of Erlangen-Nuremberg
Country: Germany

Publications

  1. ncbi request reprint Sympathetic and parasympathetic baroreflex dysfunction in familial dysautonomia
    B Stemper
    Department of Neurology, New York University, New York 10016, USA
    Neurology 63:1427-31. 2004
  2. ncbi request reprint [Autonomic disorders in polyneuropathies]
    M J Hilz
    Neurologische Klinik der Universität Erlangen Nürnberg
    Med Klin (Munich) 93:533-40. 1998
  3. ncbi request reprint Impaired baroreflex function in temporal lobe epilepsy
    Mathias Dütsch
    Department of Neurology, University of Erlangen Nuremberg, Schwabachanlage 6, 91054, Erlangen, Germany
    J Neurol 253:1300-8. 2006
  4. ncbi request reprint Decrease of sympathetic cardiovascular modulation after temporal lobe epilepsy surgery
    M J Hilz
    Department of Neurology, New York University, New York, NY, USA
    Brain 125:985-95. 2002
  5. pmc Transcranial Doppler sonography during head up tilt suggests preserved central sympathetic activation in familial dysautonomia
    M J Hilz
    Department of Neurology, University of Erlangen Nuremberg, Erlangen, Germany
    J Neurol Neurosurg Psychiatry 72:657-60. 2002
  6. ncbi request reprint Enzyme replacement therapy improves function of C-, Adelta-, and Abeta-nerve fibers in Fabry neuropathy
    M J Hilz
    Department of Neurology, New York University School of Medicine, NY 10016, USA
    Neurology 62:1066-72. 2004
  7. ncbi request reprint Assessment and evaluation of hereditary sensory and autonomic neuropathies with autonomic and neurophysiological examinations
    Max J Hilz
    Department of Neurology, University of Erlangen Nuremberg, Erlangen, Germany
    Clin Auton Res 12:I33-43. 2002
  8. ncbi request reprint [Mechanisms of cerebral autoregulation, assessment and interpretation by means of transcranial doppler sonography]
    M J Hilz
    Neurologische Klinik mit Poliklinik, Universitat Erlangen Nurnberg
    Fortschr Neurol Psychiatr 68:398-412. 2000
  9. ncbi request reprint [Erectile dysfunction. An important manifestation of autonomic diabetic neuropathy]
    M J Hilz
    Neurologische Klinik mit Poliklinik der Universität Erlangen Nürnberg
    MMW Fortschr Med 144:41-4. 2002
  10. ncbi request reprint [Physiology and methods for studying the baroreceptor reflex]
    M J Hilz
    Neurologische Klinik mit Poliklinik, Friedrich Alexander Universitat Erlangen Nurnberg
    Fortschr Neurol Psychiatr 68:37-47. 2000

Collaborators

Detail Information

Publications83

  1. ncbi request reprint Sympathetic and parasympathetic baroreflex dysfunction in familial dysautonomia
    B Stemper
    Department of Neurology, New York University, New York 10016, USA
    Neurology 63:1427-31. 2004
    ....
  2. ncbi request reprint [Autonomic disorders in polyneuropathies]
    M J Hilz
    Neurologische Klinik der Universität Erlangen Nürnberg
    Med Klin (Munich) 93:533-40. 1998
    ..Many polyneuropathies manifest autonomic disturbances. Diabetic neuropathy, the most frequent neuropathy in the western world, serves as model of the symptomatology of autonomic disturbances...
  3. ncbi request reprint Impaired baroreflex function in temporal lobe epilepsy
    Mathias Dütsch
    Department of Neurology, University of Erlangen Nuremberg, Schwabachanlage 6, 91054, Erlangen, Germany
    J Neurol 253:1300-8. 2006
    ..Most importantly, we demonstrate an impaired baroreflex function in TLE. These cardiovascular autonomic abnormalities may contribute to cardiac arrhythmia in TLE...
  4. ncbi request reprint Decrease of sympathetic cardiovascular modulation after temporal lobe epilepsy surgery
    M J Hilz
    Department of Neurology, New York University, New York, NY, USA
    Brain 125:985-95. 2002
    ..Thus, TLE surgery might contribute to reducing the risk of SUDEP...
  5. pmc Transcranial Doppler sonography during head up tilt suggests preserved central sympathetic activation in familial dysautonomia
    M J Hilz
    Department of Neurology, University of Erlangen Nuremberg, Erlangen, Germany
    J Neurol Neurosurg Psychiatry 72:657-60. 2002
    ..Cerebral autoregulation was assessed by transcranial Doppler sonography in 10 patients with familial dysautonomia and 10 age matched controls...
  6. ncbi request reprint Enzyme replacement therapy improves function of C-, Adelta-, and Abeta-nerve fibers in Fabry neuropathy
    M J Hilz
    Department of Neurology, New York University School of Medicine, NY 10016, USA
    Neurology 62:1066-72. 2004
    ..Peripheral neuropathy in Fabry disease predominantly involves small nerve fibers. Recently, enzyme replacement therapy (ERT) with recombinant human alpha-galactosidase A has become available...
  7. ncbi request reprint Assessment and evaluation of hereditary sensory and autonomic neuropathies with autonomic and neurophysiological examinations
    Max J Hilz
    Department of Neurology, University of Erlangen Nuremberg, Erlangen, Germany
    Clin Auton Res 12:I33-43. 2002
    ..Painful stimuli reveal no signs of discomfort...
  8. ncbi request reprint [Mechanisms of cerebral autoregulation, assessment and interpretation by means of transcranial doppler sonography]
    M J Hilz
    Neurologische Klinik mit Poliklinik, Universitat Erlangen Nurnberg
    Fortschr Neurol Psychiatr 68:398-412. 2000
    ..Direct, intraoperative measurements of vessel diameter confirm this conclusion...
  9. ncbi request reprint [Erectile dysfunction. An important manifestation of autonomic diabetic neuropathy]
    M J Hilz
    Neurologische Klinik mit Poliklinik der Universität Erlangen Nürnberg
    MMW Fortschr Med 144:41-4. 2002
    ..Other therapeutic options include mechanical aids, surgery, hormone replacement or sublingual apomorphine. Since 1998, Sildenafil, an effective, simple and safe oral treatment, has been available...
  10. ncbi request reprint [Physiology and methods for studying the baroreceptor reflex]
    M J Hilz
    Neurologische Klinik mit Poliklinik, Friedrich Alexander Universitat Erlangen Nurnberg
    Fortschr Neurol Psychiatr 68:37-47. 2000
    ..Pharmacological testing and "neck chamber" negative pressure stimulation of the receptors are as useful as the non-invasive computerized analysis of the interaction of spontaneous blood pressure and heart rate fluctuations...
  11. ncbi request reprint Baroreflex stimulation shows impaired cardiovagal and preserved vasomotor function in early-stage amyotrophic lateral sclerosis
    Max J Hilz
    Department of Neurology, University of Erlangen Nuremberg, Schwabachanlage 6, 91054 Erlangen, Germany
    Amyotroph Lateral Scler Other Motor Neuron Disord 3:137-44. 2002
    ..This study was undertaken to assess baroreflex-mediated vagal and sympathetic cardiovascular control of the heart and blood vessels in ALS patients...
  12. ncbi request reprint [Methods of quantitative evaluation of the autonomic nerve system]
    Max J Hilz
    Neurologische Klinik der Friedrich Alexander Universität Erlangen Nürnberg, Erlangen
    Nervenarzt 76:767-78; quiz 779-80. 2005
    ..In this review article, we focus on standard tests that allow evaluation of cardiovascular and sudomotor autonomic functions and describe methods of quantitative assessment that are better suited for research...
  13. ncbi request reprint Effects of vagus nerve stimulation on cardiovascular regulation in patients with epilepsy
    B Stemper
    Department of Neurology, University of Erlangen Nurnberg, Erlangen, Germany
    Acta Neurol Scand 117:231-6. 2008
    ..To evaluate the impact of vagus nerve stimulation (VNS) on heart rate and blood pressure (BP) modulation in epilepsy patients...
  14. ncbi request reprint Small fiber dysfunction predominates in Fabry neuropathy
    M Dutsch
    Department of Neurology, New York University, New York, NY 10016, USA
    J Clin Neurophysiol 19:575-86. 2002
    ..The results suggest a higher vulnerability of small-diameter nerve fibers than of the thickly myelinated fibers...
  15. ncbi request reprint Impairment of parasympathetic baroreflex responses in migraine patients
    E O Sanya
    Autonomic Laboratory, Department of Neurology, University of Erlangen Nuremberg, Germany
    Acta Neurol Scand 111:102-7. 2005
    ..The aim of this study was to assess baroreflex regulation of the heart rate and blood vessels in migraine patients in comparison with healthy controls...
  16. ncbi request reprint Effects of lower body negative pressure on cardiac and vascular responses to carotid baroreflex stimulation
    C M Brown
    Autonomic Laboratory, Department of Neurology, University of Erlangen Nuremberg, Schwabachanlage 6, 91054 Erlangen, Germany
    Physiol Res 52:637-45. 2003
    ..Enhanced blood pressure responses to neck suction during higher levels of LBNP are not necessarily the result of a reflex interaction but may serve to protect the circulation from fluctuations in blood pressure while standing...
  17. doi request reprint Relation between ictal asystole and cardiac sympathetic dysfunction shown by MIBG-SPECT
    F Kerling
    Epilepsy Center ZEE, Department of Neurology, University Hospital of Erlangen, Erlangen, Germany
    Acta Neurol Scand 120:123-9. 2009
    ..Tachyarrhythmias are common during epileptic seizures while bradyarrhythmias or asystoles are less frequent. Ictal asystole might be related to epilepsy-induced cardiac sympathetic denervation...
  18. ncbi request reprint Peripheral neuropathy in chronic venous insufficiency
    F Reinhardt
    Department of Neurology, University of Erlangen, Schwabachanlage 6, 91054 Erlangen, Germany
    Muscle Nerve 23:883-7. 2000
    ..Analogous to neuropathic ulcers in diabetes, the CVI-associated neuropathy may also be a cofactor in the development of venous ulcers...
  19. ncbi request reprint Enhanced external counterpulsation does not compromise cerebral autoregulation
    H Marthol
    Department of Neurology, University of Erlangen Nuremberg, Erlangen, Germany
    Acta Neurol Scand 111:34-41. 2005
    ..In this study, we assessed EECP effects on dynamic cerebral autoregulation (CA)...
  20. ncbi request reprint Altered cerebral regulation in type 2 diabetic patients with cardiac autonomic neuropathy
    H Marthol
    Department of Neurology, University of Erlangen Nuremberg, Schwabachanlage 6, 91054, Erlangen, Germany
    Diabetologia 49:2481-7. 2006
    ..We evaluated the technique of oscillatory neck suction at 0.1 Hz to quantify cerebral regulation in diabetic patients and healthy control subjects...
  21. ncbi request reprint Clonidine improves postprandial baroreflex control in familial dysautonomia
    H Marthol
    Department of Neurology, New York University School of Medicine, New York, NY, USA
    Eur J Clin Invest 33:912-8. 2003
    ..The aim of this study was to assess the effect of clonidine on cardiovascular autonomic modulation and particularly baroreflex sensitivity in familial dysautonomia after gastrostomy feeding...
  22. pmc Sudomotor function in familial dysautonomia
    A Bickel
    Department of Neurology, University Erlangen Nuremberg, Germany
    J Neurol Neurosurg Psychiatry 75:275-9. 2004
    ..We assessed peripheral sudomotor nerve fibre and sweat gland function to determine if this symptom was due to peripheral denervation hypersensitivity...
  23. doi request reprint A simple deep breathing test reveals altered cerebral autoregulation in type 2 diabetic patients
    C M Brown
    Department of Neurology, University of Erlangen Nuremberg, Erlangen, Germany
    Diabetologia 51:756-61. 2008
    ..The purpose of this study was to evaluate the autoregulation of cerebral blood flow in diabetic patients using a simple method that could easily be applied to the clinical routine screening of diabetic patients...
  24. ncbi request reprint Evaluation of cold face test bradycardia by means of spectral analysis
    B Stemper
    University of Erlangen Nuremberg, Department of Neurology, Germany
    Clin Auton Res 12:78-83. 2002
    ....
  25. ncbi request reprint Cold pressor test demonstrates residual sympathetic cardiovascular activation in familial dysautonomia
    M J Hilz
    Department of Neurology, New York University, New York, NY 10016, USA
    J Neurol Sci 196:81-9. 2002
    ..CPT assesses sympathetic cardiovascular responses independently from baroreflex function, which is compromised in FD...
  26. ncbi request reprint Deep brain stimulation improves orthostatic regulation of patients with Parkinson disease
    B Stemper
    Department of Neurology, University of Erlangen Nuernberg, Germany
    Neurology 67:1781-5. 2006
    ..To evaluate whether subthalamic nucleus (STN) stimulation has an effect on the orthostatic regulation of patients with Parkinson disease (PD), we studied cardiovascular regulation during on and off phases of STN stimulation...
  27. ncbi request reprint Influence of posture on the Valsalva manoeuvre
    W Singer
    Department of Neurology, Mayo Clinic, Rochester, MN 55905, USA
    Clin Sci (Lond) 100:433-40. 2001
    ..Sympathetic activation in the upright position seems to blunt baroreflexes, leading to similar HR responses in spite of larger changes in BP...
  28. ncbi request reprint Hemispheric influence on autonomic modulation and baroreflex sensitivity
    M J Hilz
    Department of Neurology, New York University, School of Medicine, NY 10016, USA
    Ann Neurol 49:575-84. 2001
    ..In epilepsy patients, unilateral electrical activity might derange autonomic balance between both hemispheres and contribute to cardiovascular dysregulation and sudden fatalities...
  29. ncbi request reprint Acute onset of fatal vegetative symptoms: unusual presentation of adult Alexander disease
    H B Huttner
    Department of Neurology, University of Erlangen, Erlangen, Germany
    Eur J Neurol 14:1251-5. 2007
    ..In such patients, only histology may lead to definitive diagnosis...
  30. ncbi request reprint Effects of age on the cardiac and vascular limbs of the arterial baroreflex
    C M Brown
    Autonomic Laboratory, Department of Neurology, University of Erlangen Nuremberg, Schwabachanlage 6, 91054 Erlangen, Germany
    Eur J Clin Invest 33:10-6. 2003
    ..The aim of this study was to assess the effects of ageing on baroreflex control of the heart and blood vessels...
  31. ncbi request reprint Cardiac sympathetic denervation in Ross syndrome demonstrated by MIBG-SPECT
    K Druschky
    Department of Neurology, University of Erlangen Nuernberg, Erlangen, Germany
    J Auton Nerv Syst 76:184-7. 1999
    ....
  32. doi request reprint Combined counter-maneuvers accelerate recovery from orthostatic hypotension in familial dysautonomia
    M J Hilz
    Department of Neurology, University of Erlangen Nuremberg, Germany
    Acta Neurol Scand 126:162-70. 2012
    ..In patients with familial dysautonomia (FD), prominent orthostatic hypotension (OH) endangers cerebral perfusion. Supine repositioning or abdominal compression improves systolic and diastolic blood pressure (BPsys and BPdia)...
  33. ncbi request reprint Valsalva maneuver suggests increased rigidity of cerebral resistance vessels in familial dysautonomia
    M J Hilz
    Associate Professor of Neurology, Department of Neurology, New York University Medical Center, 550 First Avenue, Suite NB 7W 11, New York, NY 10016, USA
    Clin Auton Res 12:385-92. 2002
    ..The resulting vasoconstriction would allow maintenance of normal baseline CBFV in spite of chronic recumbent hypertension...
  34. ncbi request reprint MRI-FLAIR images of the head show corticospinal tract alterations in ALS patients more frequently than T2-, T1- and proton-density-weighted images
    M J Hecht
    Department of Neurology, Friedrich Alexander University of Erlangen Nuremberg, Schwabachanlage 6, Erlangen D 91054, Germany
    J Neurol Sci 186:37-44. 2001
    ..Because of an overlap with physiological findings, they have to be interpreted cautiously, with the exception of hyperintense signals at the subcortical precentral gyrus...
  35. ncbi request reprint Impaired cardiovagal and vasomotor responses to baroreceptor stimulation in type II diabetes mellitus
    E O Sanya
    Autonomic Laboratory, Department of Neurology, University of Erlangen Nuremberg, Schwabachanlage 6, 91054 Erlangen, Germany
    Eur J Clin Invest 33:582-8. 2003
    ..However, the role of sympathetic mediated baroreflex vasomotor control of the blood vessels is not well defined. We therefore assessed the vasomotor responses to sinusoidal baroreceptor stimulation in diabetic patients...
  36. ncbi request reprint Neuropathy is a major contributing factor to diabetic erectile dysfunction
    M J Hecht
    Department of Neurology, University of Erlangen-Nuremberg, Erlangen, Germany
    Neurol Res 23:651-4. 2001
    ..Some tests even suggested neuropathy more often in diabetic than in neuropathic ED. The findings support the hypothesis that neuropathy contributes significantly to the pathophysiology of ED in diabetes mellitus...
  37. ncbi request reprint Cardiovascular autonomic function in poststroke patients
    M Dutsch
    Department of Neurology, University of Erlangen Nuremberg, Schwabachanlage 6, 91054 Erlangen, Germany
    Neurology 69:2249-55. 2007
    ..However, there are few data on cardiovascular autonomic function in post-acute stroke patients...
  38. ncbi request reprint Oral mucosal blood flow following dry ice stimulation in humans
    J G Heckmann
    Department of Neurology, University of Erlangen Nuremberg, Germany
    Clin Auton Res 10:317-21. 2000
    ..Therefore, assessment of stimulated mucosal blood flow appears to be a promising tool to investigate the pathophysiology of a number of neurologic symptoms, eg, the burning mouth syndrome...
  39. ncbi request reprint Interictal cardiac autonomic dysfunction in temporal lobe epilepsy demonstrated by [(123)I]metaiodobenzylguanidine-SPECT
    A Druschky
    Department of Neurology, University of Erlangen-Nuremberg, Germany
    Brain 124:2372-82. 2001
    ..MIBG-SPECT demonstrates altered post-ganglionic cardiac sympathetic innervation. This dysfunction might carry an increased risk of cardiac abnormalities...
  40. ncbi request reprint Critical illness polyneuropathy: clinical findings and cell culture assay of neurotoxicity assessed by a prospective study
    A Druschky
    Department of Neurology, University of Erlangen Nuernberg, Schwabachanlage 6, 91054 Erlangen, Germany
    Intensive Care Med 27:686-93. 2001
    ....
  41. ncbi request reprint Assessment of the neurogenic flare reaction in small-fiber neuropathies
    A Bickel
    Department of Neurology, University Erlangen Nuremberg, Erlangen, Germany andreas bickel med uni erlangen de
    Neurology 59:917-9. 2002
    ..Flare size, but not laser Doppler flux, clearly distinguished patients from controls at both locations (p < 0.01) and may be useful for evaluation of small-fiber neuropathies...
  42. doi request reprint Neurological complications in Fabry disease
    M Dutsch
    University of Erlangen Nuremberg, Schwabachanlage 6, Erlangen, Germany
    Rev Med Interne 31:S243-50. 2010
    ....
  43. ncbi request reprint Sympathetic and parasympathetic pupillary dysfunction in familial dysautonomia
    M Dutsch
    Department of Neurology, New York University, New York, NY 10016, USA
    J Neurol Sci 195:77-83. 2002
    ..05). The non-invasive technique of IPM demonstrates dysfunction not only of the cranial parasympathetic, but also of the cranial sympathetic nervous system and, thus, further characterizes autonomic dysfunction in FD...
  44. ncbi request reprint Evaluation of peripheral and autonomic nerve function in Fabry disease
    M J Hilz
    Department of Neurology, University of Erlangen Nuremberg, Erlangen, Germany
    Acta Paediatr Suppl 91:38-42. 2002
    ....
  45. pmc Dermal microdialysis provides evidence for hypersensitivity to noradrenaline in patients with familial dysautonomia
    A Bickel
    Neurologische Klinik, Universitat Erlangen Nurnberg, Schwabachanlage 6, 91054 Erlangen, Germany
    J Neurol Neurosurg Psychiatry 73:299-302. 2002
    ..To use the technique of dermal microdialysis to examine sensitivity of skin vessels to noradrenaline (NA) in patients with familial dysautonomia (FD) and in healthy controls...
  46. ncbi request reprint Enhanced external counterpulsation improves skin oxygenation and perfusion
    M J Hilz
    Department of Neurology, Friedrich Alexander University Erlangen Nuremberg, Erlangen, Germany
    Eur J Clin Invest 34:385-91. 2004
    ..This study was performed to assess acute effects of EECP on superficial skin blood flow, transdermal oxygen and carbon dioxide pressures...
  47. ncbi request reprint [Diagnosis and treatment of polyneuropathy: what can the family doctor do?]
    M Hecht
    Neurologische Klinik mit Poliklinik, Friedrich Alexander Universität Erlangen
    MMW Fortschr Med 145:81-5. 2003
    ..If the etiology of the polyneuropathy is revealed specific therapy can be started. Furthermore, polyneuropathic symptoms can be ameliorated independently of the underlying cause...
  48. ncbi request reprint [Cerebrovascular circulation from a clinical view. Historical review, physiology, pathophysiology, diagnostic and therapeutic aspects]
    J G Heckmann
    Neurologische Klinik und Poliklinik, Universitat Erlangen Nurnberg
    Med Klin (Munich) 96:583-92. 2001
    ..o.)...
  49. ncbi request reprint [Erectile dysfunction--value of neurophysiologic diagnostic procedures]
    M J Hilz
    Neurologische Klinik der Universität Erlangen Nürnberg
    Urologe A 42:1345-50. 2003
    ..In addition, the assessment of heart rate variability at rest, during metronomic breathing, Valsalva maneuver, and active standing might be helpful to identify an autonomic neuropathy as the cause of erectile dysfunction...
  50. ncbi request reprint [Syncope - a systematic overview of classification, pathogenesis, diagnosis and management]
    M J Hilz
    Neurologische Klinik mit Poliklinik der Universität Erlangen Nürnberg, Germany
    Fortschr Neurol Psychiatr 70:95-107. 2002
    ..In postprandial hypotension, octreotide, a somatostatin analogue, prostaglandin inhibitors such as indomethacin or ibuprofen, as well as metoclopramide or two cups of coffee per day might be beneficial...
  51. pmc Sex differences and lateral asymmetry in heart rate modulation in patients with temporal lobe epilepsy
    A Kirchner
    Department of Neurology, University of Erlangen Nuremberg, Erlangen, Germany
    J Neurol Neurosurg Psychiatry 73:73-5. 2002
    ..24, df = 2.58/27, p < 0.001). These results confirm the right hemispheric lateralisation of sympathetic cardiac control in male patients...
  52. ncbi request reprint Hyperintense and hypointense MRI signals of the precentral gyrus and corticospinal tract in ALS: a follow-up examination including FLAIR images
    Martin J Hecht
    Department of Neurology, Friedrich Alexander University of Erlangen Nuremberg, Schwabachanlage 6, D 91054 Erlangen, Germany
    J Neurol Sci 199:59-65. 2002
    ..Their specificity and clinical relevance have to be clarified further...
  53. doi request reprint Waiting for platelet counts causes unsubstantiated delay of thrombolysis therapy
    L Breuer
    Department of Neurology, University of Erlangen Nuremberg, Erlangen Nuremberg, Germany
    Eur Neurol 69:317-20. 2013
    ..We aimed to assess the incidence of thrombocytopenia in IVT patients, outcome after thrombolysis in affected patients and the time gained by initiating treatment prior to availability of PC results...
  54. doi request reprint Radiopacity of intracerebral hemorrhage correlates with perihemorrhagic edema
    I Wagner
    Department of Neurology, University of Erlangen Nuremberg, Erlangen, Germany
    Eur J Neurol 19:525-8. 2012
    ..We investigated the relationship between ICH radiopacity on CT as a marker of hematoma iron content and perihemorrhagic edema (PHE) after ICH...
  55. ncbi request reprint [Female sexual dysfunction: a systematic overview of classification, pathophysiology, diagnosis and treatment]
    H Marthol
    New York University School of Medicine, Department of Neurology, New York, NY, USA
    Fortschr Neurol Psychiatr 72:121-35. 2004
    ..The efficacy of various other medications, e.g. sildenafil, L-arginine, yohimbine, phentolamine, apomorphine and prostaglandin E1, in the treatment of female sexual dysfunction is still under investigation...
  56. ncbi request reprint Mononeuritis multiplex caused by Coxiella burnetii infection (Q fever)
    J B Sommer
    Department of Neurology, University of Erlangen Nuremberg, Erlangen, Germany
    Acta Neurol Scand 106:371-3. 2002
    ..This is the first report on Q fever related mononeuritis multiplex. Prolonged antibiotic treatment may be required to prevent relapsing infection from the resistant bacterium...
  57. doi request reprint In vivo detection of hepatitis C virus (HCV) RNA in the brain in a case of encephalitis: evidence for HCV neuroinvasion
    F Seifert
    Department of Neurology, University of Erlangen Nuremberg, Erlangen, Germany
    Eur J Neurol 15:214-8. 2008
    ..This is supported by the fact that there is a growing body of literature on HCV-induced cerebral dysfunction and laboratory findings indicating HCV neuroinvasion...
  58. pmc Acetylcholinesterase inhibition: a novel approach in the treatment of neurogenic orthostatic hypotension
    W Singer
    Department of Neurology, Mayo Clinic, Rochester, Minnesota 55905, USA
    J Neurol Neurosurg Psychiatry 74:1294-8. 2003
    ..Pharmacological treatment of orthostatic hypotension is often limited because of troublesome supine hypertension...
  59. ncbi request reprint Peripheral nervous system involvement in Fabry disease: role in morbidity and mortality
    Max J Hilz
    Department of Neurology, University of Erlangen Nuremberg, Erlangen, Germany
    Clin Ther 29:S11-2. 2007
  60. ncbi request reprint Effect of physical countermaneuvers on orthostatic hypotension in familial dysautonomia
    Marcin Tutaj
    Department of Neurology, Jagiellonian University, Botaniczna 3, 31503, Krakow, Poland
    J Neurol 253:65-72. 2006
    ..Suitability and effectiveness of a specific countermaneuver depends on the orthopedic or neurological complications of each FD patient and must be individually tested before a therapeutic recommendation can be given...
  61. ncbi request reprint Assessment of cerebrovascular and cardiovascular responses to lower body negative pressure as a test of cerebral autoregulation
    Clive M Brown
    Autonomic Laboratory, Department of Neurology, University of Erlangen Nuremberg, Schwabachanlage 6, Germany
    J Neurol Sci 208:71-8. 2003
    ..Furthermore, assessment of cardiovascular and cerebrovascular parameters during LBNP may provide a useful clinical test of cerebral autoregulation...
  62. ncbi request reprint Differential impairment of the sudomotor and nociceptor axon-reflex in diabetic peripheral neuropathy
    Martin Berghoff
    Department of Neurology, University of Munster, Munster, Germany
    Muscle Nerve 33:494-9. 2006
    ..These findings suggest that the functional abnormalities in diabetic peripheral neuropathy are not homogeneous and that C-fiber subclasses are differentially affected in type 1 and 2 diabetes mellitus...
  63. ncbi request reprint Right ventromedial prefrontal lesions result in paradoxical cardiovascular activation with emotional stimuli
    Max J Hilz
    Department of Neurology, New York University, New York, NY, USA
    Brain 129:3343-55. 2006
    ..The paradoxical sympathetic disinhibition in VMPFC-R patients may increase their risk of sympathetic hyperexcitability with negative consequences such as anxiety, hypertension or cardiac arrhythmias...
  64. ncbi request reprint Quantitative studies of autonomic function
    Max J Hilz
    Department of Neurology, New York University Medical Center, 550 First Avenue, Suite NB 7W11, New York, NY 10016, USA
    Muscle Nerve 33:6-20. 2006
    ..Finally, we discuss microneurography as a technique of direct recording of muscle sympathetic nerve activity...
  65. ncbi request reprint Abnormal heart rate and blood pressure responses to baroreflex stimulation in multiple sclerosis patients
    Emmanuel O Sanya
    Autonomic Laboratory, Dept of Neurology, University of Erlangen Nuremberg, Erlangen, Germany
    Clin Auton Res 15:213-8. 2005
    ..27+/-0.29 ln ms(2)). These results indicate that in MS patients, baroreflex dysfunction is not only restricted to the cardiovagal limb of the baroreflex, but that the sympathetic modulation of the blood vessels is also affected...
  66. ncbi request reprint Orthostatic challenge reveals impaired vascular resistance control, but normal venous pooling and capillary filtration in familial dysautonomia
    Clive M Brown
    Autonomic Laboratory, Department of Neurology, University of Erlangen Nuremberg, Schwabachanlage 6, 91054 Erlangen, Germany
    Clin Sci (Lond) 104:163-9. 2003
    ..This may be due, in part, to a preserved myogenic response to increased vascular pressure in the dependent vascular beds...
  67. ncbi request reprint Terminal vessel hyperperfusion despite organ hypoperfusion in familial dysautonomia
    Brigitte Stemper
    Department of Neurology, New York University, New York, NY, USA
    Clin Sci (Lond) 105:295-301. 2003
    ..Both the reduced limb perfusion and the dysfunctional end-organ blood supply in FD patients are likely to be major contributors to the vasomotor instability observed in these subjects, particularly during periods of stress...
  68. ncbi request reprint Effect of cold face stimulation on cerebral blood flow in humans
    Clive M Brown
    Department of Neurology, Autonomic Laboratory, University of Erlangen Nuremberg, Schwabachanlage 6, 91054 Erlangen, Germany
    Brain Res Bull 61:81-6. 2003
    ..However, responses of the cerebral blood flow have not yet been evaluated. We undertook this study to assess the effect of cold face stimulation on the cerebral circulation in humans...
  69. ncbi request reprint Postischemic cutaneous hyperperfusion in the presence of forearm hypoperfusion suggests sympathetic vasomotor dysfunction in Fabry disease
    Brigitte Stemper
    Dept of Neurology, University of Erlangen Nurnberg, Schwabachanlage 6, 91054 Erlangen, Germany
    J Neurol 250:970-6. 2003
    ....
  70. ncbi request reprint Delayed cerebrovascular autoregulatory response to ergometer exercise in normotensive elderly humans
    Josef G Heckmann
    Department of Neurology, University of Erlangen Nuremberg, Erlangen, Germany
    Cerebrovasc Dis 16:423-9. 2003
    ..The aim of this study was to determine the effect of ergometer stress on cerebrovascular haemodynamics in elderly healthy individuals in comparison with young healthy individuals, using non-invasive methods...
  71. ncbi request reprint Cerebral autoregulation is compromised during simulated fluctuations in gravitational stress
    Clive M Brown
    Autonomic Laboratory, Dept of Neurology, University of Erlangen Nuremberg, Germany
    Eur J Appl Physiol 91:279-86. 2004
    ..Furthermore, this effect seems to be more pronounced at higher frequencies of oscillatory stress...
  72. ncbi request reprint Dynamic cerebral autoregulation remains stable during physical challenge in healthy persons
    Miroslaw Brys
    Department of Neurology, New York University School of Medicine, 550 First Avenue, New York, NY 10016, USA
    Am J Physiol Heart Circ Physiol 285:H1048-54. 2003
    ..CA seems to compensate for the hemodynamic effects and increasing CO2 levels during exercise...
  73. ncbi request reprint Impaired cardiovascular responses to baroreflex stimulation in open-angle and normal-pressure glaucoma
    Clive M Brown
    Department of Neurology, University of Erlangen Nuremberg, Schwabachanlage 6, Germany
    Clin Sci (Lond) 102:623-30. 2002
    ....
  74. ncbi request reprint Heart rate-dependent electrocardiogram abnormalities in patients with postural tachycardia syndrome
    Wolfgang Singer
    Department of Neurology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
    Auton Neurosci 103:106-13. 2003
    ..These findings may reflect intrinsic cardiac electrophysiologic abnormalities or may be secondary due to abnormalities of cardiac autonomic innervation...
  75. ncbi request reprint Dynamic cerebral autoregulation is impaired in glaucoma
    Marcin Tutaj
    Department of Neurology, University of Erlangen Nuremberg, Schwabachanlage 6, D 91054 Erlangen, Germany
    J Neurol Sci 220:49-54. 2004
    ..Although there is evidence of vasomotor dysregulation with decreased peripheral and ocular blood flow, cerebral autoregulation (CA) has not yet been evaluated. The aim of our study was to assess dynamic CA in patients with NPG and POAG...
  76. ncbi request reprint Outcome of epilepsy surgery correlates with sympathetic modulation and neuroimaging of the heart
    Max J Hilz
    Department of Neurology, New York University, New York, NY 10016, USA
    J Neurol Sci 216:153-62. 2003
    ..Both findings are possible risk factors for sudden unexplained death and might be relevant for risk stratification in epilepsy patients...
  77. ncbi request reprint Evidence of an intrinsic sinus node abnormality in patients with postural tachycardia syndrome
    Wolfgang Singer
    Department of Neurology, Mayo Clinic, Rochester, Minn 55905, USA
    Mayo Clin Proc 77:246-52. 2002
    ....
  78. ncbi request reprint Cerebral autoregulation improves in epilepsy patients after temporal lobe surgery
    Matthias Dutsch
    Department of Neurology, University of Erlangen Nuremberg, Erlangen, Germany
    J Neurol 251:1190-7. 2004
    ..The enhanced cerebrovascular stability after surgery may improve autonomic balance in epilepsy patients...
  79. ncbi request reprint Vascular and neural mechanisms of ACh-mediated vasodilation in the forearm cutaneous microcirculation
    Martin Berghoff
    Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts 02215, USA
    J Appl Physiol 92:780-8. 2002
    ..The findings suggest that prostanoids do not contribute significantly to basal CuBF or endothelium-dependent vasodilation in the forearm microcirculation. In contrast, prostanoids are mediators of the ACh-provoked axon reflex...
  80. ncbi request reprint Hereditary dysautonomias: current knowledge and collaborations for the future
    Math P Cuajungco
    Harvard Institute of Human Genetics, 77 Avenue Louis Pasteur, HIM Building, Room 422, Boston, MA 02115, USA
    Clin Auton Res 13:180-95. 2003
    ....
  81. doi request reprint Stroke-induced sudden-autonomic death: areas of fatality beyond the insula
    Max J Hilz
    Stroke 39:2421-2. 2008
  82. ncbi request reprint Assessing function and pathology in familial dysautonomia: assessment of temperature perception, sweating and cutaneous innervation
    Max J Hilz
    Department of Neurology, New York University Medical Center, 550 First Avenue, Suite NB 7W11, New York, NY, 10016, USA
    Brain 127:2090-8. 2004
    ..Decreased SP and CGRP-ir nerves suggest that the FD gene mutation causes secondary neurotransmitter depletions. Empty Schwann cell sheaths and VIP-ir nerves suggest active denervation and regeneration...
  83. ncbi request reprint Inherited autonomic neuropathies
    Felicia B Axelrod
    Department of Neurology, New Yourk University School of Medicine, New York, NY 10016, USA
    Semin Neurol 23:381-90. 2003
    ..Replacement or definitive therapies are not available for any of the disorders so that treatment remains supportive and directed toward specific symptoms...