Thomas Hillemacher

Summary

Affiliation: University of Erlangen-Nuremberg
Country: Germany

Publications

  1. ncbi request reprint Recurrent hyponatremia under desmopressin overdosing: is abuse a possible explication?
    Thomas Hillemacher
    Department of Psychiatry and Psychotherapy, University Hospital Erlangen, D 91054 Erlangen, Germany
    Am J Emerg Med 25:239-40. 2007
  2. ncbi request reprint Role of appetite-regulating peptides in alcohol craving: an analysis in respect to subtypes and different consumption patterns in alcoholism
    Thomas Hillemacher
    Department of Psychiatry and Psychotherapy, University Hospital Erlangen, Erlangen, Germany
    Alcohol Clin Exp Res 31:950-4. 2007
  3. doi request reprint Neurobiology and treatment in alcoholism--recent findings regarding Lesch's typology of alcohol dependence
    Thomas Hillemacher
    Department of Psychiatry and Psychotherapy, University Hospital Erlangen, Schwabachanlage 6, D 91054 Erlangen, Germany
    Alcohol Alcohol 43:341-6. 2008
  4. ncbi request reprint Evidence of an association of leptin serum levels and craving in alcohol dependence
    Thomas Hillemacher
    Department of Psychiatry and Psychotherapy, University of Erlangen Nuremberg, Schwabachanlage 6, D 91054 Erlangen, Germany
    Psychoneuroendocrinology 32:87-90. 2007
  5. doi request reprint Promoter specific methylation of the dopamine transporter gene is altered in alcohol dependence and associated with craving
    Thomas Hillemacher
    Department of Psychiatry and Psychotherapy, University of Erlangen Nuremberg, Schwabachanlage 6, D 91054 Erlangen, Germany
    J Psychiatr Res 43:388-92. 2009
  6. doi request reprint Increased levels of adiponectin and resistin in alcohol dependence--possible link to craving
    Thomas Hillemacher
    Department of Psychiatry and Psychotherapy, University of Erlangen Nuremberg, Germany
    Drug Alcohol Depend 99:333-7. 2009
  7. ncbi request reprint Apolipoprotein E gene polymorphism and previous alcohol withdrawal seizures
    Julia Wilhelm
    Department of Psychiatry and Psychotherapy, University of Erlangen Nuremberg, Schwabachanlage 6, D 91054 Erlangen, Germany
    J Psychiatr Res 41:871-5. 2007
  8. doi request reprint Association of V89L SRD5A2 polymorphism with craving and serum leptin levels in male alcohol addicts
    Bernd Lenz
    Department of Psychiatry and Psychotherapy, Friedrich Alexander University of Erlangen Nuremberg, Schwabachanlage 6 10, 91054 Erlangen, Germany
    Psychopharmacology (Berl) 224:421-9. 2012
  9. ncbi request reprint Apolipoprotein E4 genotype is not associated with short-term cognition deficits during alcohol withdrawal
    Julia Wilhelm
    Department of Psychiatry and Psychotherapy, University of Erlangen Nuremberg, Schwabachanlage 6, D 91054 Erlangen, Germany
    Alcohol 37:151-6. 2005
  10. ncbi request reprint The TTTAn aromatase (CYP19A1) polymorphism is associated with compulsive craving of male patients during alcohol withdrawal
    Bernd Lenz
    Department of Psychiatry and Psychotherapy, Friedrich Alexander University of Erlangen Nuremberg, Erlangen, Germany
    Psychoneuroendocrinology 36:1261-4. 2011

Collaborators

Detail Information

Publications64

  1. ncbi request reprint Recurrent hyponatremia under desmopressin overdosing: is abuse a possible explication?
    Thomas Hillemacher
    Department of Psychiatry and Psychotherapy, University Hospital Erlangen, D 91054 Erlangen, Germany
    Am J Emerg Med 25:239-40. 2007
  2. ncbi request reprint Role of appetite-regulating peptides in alcohol craving: an analysis in respect to subtypes and different consumption patterns in alcoholism
    Thomas Hillemacher
    Department of Psychiatry and Psychotherapy, University Hospital Erlangen, Erlangen, Germany
    Alcohol Clin Exp Res 31:950-4. 2007
    ..Aim of this analysis was to search for differences regarding an association between these peptides and alcohol craving with respect to different subtypes and beverage consumption patterns in patients with alcohol dependence...
  3. doi request reprint Neurobiology and treatment in alcoholism--recent findings regarding Lesch's typology of alcohol dependence
    Thomas Hillemacher
    Department of Psychiatry and Psychotherapy, University Hospital Erlangen, Schwabachanlage 6, D 91054 Erlangen, Germany
    Alcohol Alcohol 43:341-6. 2008
    ..This applies in particular for genetic and neuroendocrinological factors, differences in the regulation of NMDA receptor-mediated glutamatergic neurotransmission, and in response to acamprosate and naltrexone treatment...
  4. ncbi request reprint Evidence of an association of leptin serum levels and craving in alcohol dependence
    Thomas Hillemacher
    Department of Psychiatry and Psychotherapy, University of Erlangen Nuremberg, Schwabachanlage 6, D 91054 Erlangen, Germany
    Psychoneuroendocrinology 32:87-90. 2007
    ..160, t=5.793, p<0.001) with a power of 1.00. In contrast to previous results describing an association only in female patients, this power-based analysis shows that leptin is associated with alcohol craving in both genders...
  5. doi request reprint Promoter specific methylation of the dopamine transporter gene is altered in alcohol dependence and associated with craving
    Thomas Hillemacher
    Department of Psychiatry and Psychotherapy, University of Erlangen Nuremberg, Schwabachanlage 6, D 91054 Erlangen, Germany
    J Psychiatr Res 43:388-92. 2009
    ..Furthermore, hypermethylation of the DAT-promoter may play an important role in dopaminergic neurotransmission and is associated with decreased alcohol craving...
  6. doi request reprint Increased levels of adiponectin and resistin in alcohol dependence--possible link to craving
    Thomas Hillemacher
    Department of Psychiatry and Psychotherapy, University of Erlangen Nuremberg, Germany
    Drug Alcohol Depend 99:333-7. 2009
    ..Furthermore, adiponectin may be involved in the neurobiology of alcohol craving, possibly via its effects on the hypothalamic circuits...
  7. ncbi request reprint Apolipoprotein E gene polymorphism and previous alcohol withdrawal seizures
    Julia Wilhelm
    Department of Psychiatry and Psychotherapy, University of Erlangen Nuremberg, Schwabachanlage 6, D 91054 Erlangen, Germany
    J Psychiatr Res 41:871-5. 2007
    ..Our findings suggest an association between the apolipoprotein E3 gene variant and an elevated risk of alcohol withdrawal seizures. These preliminary results must be validated in further studies...
  8. doi request reprint Association of V89L SRD5A2 polymorphism with craving and serum leptin levels in male alcohol addicts
    Bernd Lenz
    Department of Psychiatry and Psychotherapy, Friedrich Alexander University of Erlangen Nuremberg, Schwabachanlage 6 10, 91054 Erlangen, Germany
    Psychopharmacology (Berl) 224:421-9. 2012
    ..The steroid 5-α reductase 2 (SRD5A2) converts testosterone to dihydrotestosterone and thereby causes increased androgenic potency...
  9. ncbi request reprint Apolipoprotein E4 genotype is not associated with short-term cognition deficits during alcohol withdrawal
    Julia Wilhelm
    Department of Psychiatry and Psychotherapy, University of Erlangen Nuremberg, Schwabachanlage 6, D 91054 Erlangen, Germany
    Alcohol 37:151-6. 2005
    ....
  10. ncbi request reprint The TTTAn aromatase (CYP19A1) polymorphism is associated with compulsive craving of male patients during alcohol withdrawal
    Bernd Lenz
    Department of Psychiatry and Psychotherapy, Friedrich Alexander University of Erlangen Nuremberg, Erlangen, Germany
    Psychoneuroendocrinology 36:1261-4. 2011
    ..Future investigations should enrol women and consider sex hormone levels for further clarification of the observed TTTAn-craving relationship...
  11. ncbi request reprint Ghrelin levels are increased in alcoholism
    Thomas Kraus
    Department of Psychiatry and Psychotherapy, University Hospital, Erlangen, Germany
    Alcohol Clin Exp Res 29:2154-7. 2005
    ..Therefore, the aim of the present pilot study was to determine whether the gut-derived peptide ghrelin which increases hunger and food intake is altered and associated with alcohol craving in alcoholic patients..
  12. doi request reprint Epigenetic downregulation of atrial natriuretic peptide but not vasopressin mRNA expression in females with eating disorders is related to impulsivity
    Helge Frieling
    Department of Psychiatry and Psychotherapy, Friedrich Alexander University Erlangen Nuremberg, Erlangen, Germany
    Neuropsychopharmacology 33:2605-9. 2008
    ..ANP mRNA expression was inversely associated with impaired impulse regulation. We conclude that epigenetic mechanisms may contribute to the known alterations of ANP homeostasis in women with eating disorders...
  13. doi request reprint Elevation of homocysteine levels is only partially reversed after therapy in females with eating disorders
    Julia Wilhelm
    Department of Psychiatry and Psychotherapy, University Hospital Erlangen, Erlangen, Germany
    J Neural Transm 117:521-7. 2010
    ..These findings add further evidence to the hypothesis that homocysteine might be involved in the pathophysiology of anorexia and bulimia nervosa...
  14. doi request reprint Alpha-synuclein mRNA levels correspond to beck depression inventory scores in females with eating disorders
    Helge Frieling
    Department of Psychiatry and Psychotherapy, University Erlangen Nuremberg, Erlangen, Germany
    Neuropsychobiology 58:48-52. 2008
    ..Further investigations in patients with depression as a sole diagnosis are needed to support its role in the pathogenesis of major depression...
  15. doi request reprint ERK1/2 protein and mRNA levels in human blood are linked to smoking behavior
    Bernd Lenz
    Department of Psychiatry and Psychotherapy, Friedrich Alexander University of Erlangen Nuremberg, Germany
    Addict Biol 17:1026-35. 2012
    ....
  16. doi request reprint Elevated cannabinoid 1 receptor mRNA is linked to eating disorder related behavior and attitudes in females with eating disorders
    Helge Frieling
    Department of Psychiatry and Psychotherapy, University Hospital Erlangen, Germany
    Psychoneuroendocrinology 34:620-4. 2009
    ..The endocannabinoid system is involved in the regulation of appetite, food intake and energy balance...
  17. ncbi request reprint Volume intake and craving in alcohol withdrawal
    Thomas Hillemacher
    Department of Psychiatry and Psychotherapy, University of Erlangen Nuremberg, Schwabachanlage 6, D 91054 Erlangen, Germany
    Alcohol Alcohol 41:61-5. 2006
    ..The present study was undertaken to evaluate whether the daily volume intake of alcoholic beverages is associated with craving in patients undergoing alcohol withdrawal...
  18. ncbi request reprint Association of the long allele of the 5-HTTLPR polymorphism with compulsive craving in alcohol dependence
    Stefan Bleich
    Department of Psychiatry and Psychotherapy, University of Erlangen Nuremberg, Schwabachanlage 6, D 91054 Erlangen, Germany
    Alcohol Alcohol 42:509-12. 2007
    ..Various studies have reported a role of the serotonin transporter-linked polymorphic region (5-HTTLPR) in alcoholism...
  19. doi request reprint Epigenetic dysregulation of dopaminergic genes in eating disorders
    Helge Frieling
    Department of Psychiatry and Psychotherapy, University Hospital Erlangen, Erlangen, Germany
    Int J Eat Disord 43:577-83. 2010
    ....
  20. doi request reprint Epigenetic regulation and gene expression of vasopressin and atrial natriuretic peptide in alcohol withdrawal
    Thomas Hillemacher
    Department of Psychiatry and Psychotherapy, University Hospital Erlangen, Germany
    Psychoneuroendocrinology 34:555-60. 2009
    ..Further studies focusing on longitudinal changes of epigenetic regulation and gene expression of both peptides are needed to clarify the pathophysiological role of these findings...
  21. ncbi request reprint Alpha-synuclein protein levels are increased in alcoholic patients and are linked to craving
    Dominikus Bönsch
    Department of Psychiatry and Psychotherapy, Friedrich Alexander University of Erlangen Nuremberg, Erlangen, Germany
    Alcohol Clin Exp Res 29:763-5. 2005
    ..The aim of the current study was to investigate whether protein levels of alpha synuclein in alcoholics are changed and possibly influence alcohol craving...
  22. ncbi request reprint Nicotine dependence is associated with compulsive alcohol craving
    Thomas Hillemacher
    Department of Psychiatry and Psychotherapy, University of Erlangen Nuremberg, Germany
    Addiction 101:892-7. 2006
    ..To investigate a possible association of nicotine dependence and alcohol craving...
  23. ncbi request reprint An assessment of the potential value of elevated homocysteine in predicting alcohol-withdrawal seizures
    Stefan Bleich
    Department of Psychiatry and Psychotherapy, Friedrich Alexander University of Erlangen Nuremberg, Erlangen, Germany
    Epilepsia 47:934-8. 2006
    ..The aim of the present study was to calculate the best predictive cutoff value of plasma homocysteine levels in actively drinking alcoholics (n = 88) with first-onset alcohol-withdrawal seizures...
  24. ncbi request reprint Plasma homocysteine concentrations do not influence craving in alcohol withdrawal
    Thomas Hillemacher
    Department of Psychiatry and Psychotherapy, University of Erlangen Nuremberg, Schwabachanlage 6, D 91054 Erlangen, Germany
    Alcohol 34:211-5. 2004
    ..Therefore, further research about alcohol craving should focus on neurobiologic factors other than homocysteine...
  25. doi request reprint Polymorphism of the long polyglutamine tract in the human androgen receptor influences craving of men in alcohol withdrawal
    Bernd Lenz
    Department of Psychiatry and Psychotherapy, Friedrich Alexander University of Erlangen Nuremberg, Schwabachanlage 6 10, D 91054 Erlangen, Germany
    Psychoneuroendocrinology 34:968-71. 2009
    ..In summary, the presented data points to an underestimated role of the genetic regulation of androgens in the pathogenesis of alcohol dependence and related disorders...
  26. ncbi request reprint Elevated prolactin serum levels and history of alcohol withdrawal seizures
    Thomas Hillemacher
    Department of Psychiatry and Psychotherapy, University of Erlangen Nuremberg, Germany
    J Psychiatr Res 41:702-6. 2007
    ..Prolactin has been discussed to be useful for differential diagnosis in epilepsia. Aim of the present study was to investigate the association between prolactin serum levels and previous alcohol withdrawal seizures...
  27. doi request reprint Sex hormone activity in alcohol addiction: integrating organizational and activational effects
    Bernd Lenz
    Department of Psychiatry and Psychotherapy, Friedrich Alexander University of Erlangen Nuremberg, Germany
    Prog Neurobiol 96:136-63. 2012
    ..The early sex hormone activity model of alcohol addiction may prove to be a valuable tool in the development of preventive and therapeutic strategies...
  28. doi request reprint NGF plasma levels increase due to alcohol intoxication and decrease during withdrawal
    Annemarie Heberlein
    Department of Psychiatry and Psychotherapy, University Hospital Erlangen Nuremberg, Schwabachanlage 6, D 91054 Erlangen, Germany
    Psychoneuroendocrinology 33:999-1003. 2008
    ..These results suggest that NGF plasma levels increase as part of a regulation mechanism that counteracts alcohol intoxication...
  29. doi request reprint N-methyl-D-aspartate 2b receptor subtype (NR2B) promoter methylation in patients during alcohol withdrawal
    Teresa Biermann
    Department of Psychiatry and Psychotherapy, University Hospital of Erlangen, Erlangen, Germany
    J Neural Transm 116:615-22. 2009
    ..55; P = 0.013; daily ethanol intake: rho = -0.46; P = 0.043). These findings might explain the observation of an impact of alcohol consumption patterns on the gravity of withdrawal symptoms...
  30. ncbi request reprint Influence of beer, wine and spirits consumption on craving
    Thomas Hillemacher
    Department of Psychiatry and Psychotherapy, University of Erlangen Nuremberg, Germany
    Addict Biol 10:181-6. 2005
    ..In addition, it is an important predictor for both obsessive and compulsive craving. Further studies are needed to clarify the pathophysiological basis of this finding...
  31. ncbi request reprint Different allele-distribution of mthfr 677 C -> T and mthfr -393 C -> a in patients classified according to subtypes of Lesch's typology
    Dominikus Bönsch
    Department of Psychiatry and Psychotherapy, Friedrich Alexander University of Erlangen Nuremberg, Schwabachanlage 6 91054 Erlangen, Germany
    Alcohol Alcohol 41:364-7. 2006
    ..2 (SD 8.9) years) were classified according to LT and divided into four groups: LT 1 (n = 26), LT 2 (n = 65), LT 3 (n = 58), and LT 4 (n = 18). Total plasma homocysteine levels and MTHFR genotypes -393, 677, and 1,793 were determined...
  32. ncbi request reprint Prolactin serum levels and alcohol craving - an analysis using Lesch's typology
    Thomas Hillemacher
    Department of Psychiatry and Psychotherapy, University of Erlangen Nuremberg, Erlangen, Germany
    Neuropsychobiology 53:133-6. 2006
    ..Prolactin secretion is closely connected to dopaminergic transmission that is known to play a crucial role in mediating reinforcement and craving in alcoholism...
  33. ncbi request reprint Depressive symptoms may explain elevated plasma levels of homocysteine in females with eating disorders
    Helge Frieling
    Department of Psychiatry and Psychotherapy, University of Erlangen Nuremberg, Schwabachanlage 6, 91054 Erlagen, Germany
    J Psychiatr Res 42:83-6. 2008
    ..8; df = 42; P = 0.008). Presence of depressive symptoms may explain elevated homocysteine levels previously reported in patients with eating disorders or vice versa. Longitudinal studies are needed to unravel this hen or egg problem...
  34. pmc Predictors of binge drinking in adolescents: ultimate and distal factors - a representative study
    Carolin Donath
    Department Medical Psychology and Medical Sociology, Psychiatric University Hospital Erlangen Friedrich Alexander Universität Erlangen Nürnberg, Schwabachanlage 6, 91054 Erlangen, Germany
    BMC Public Health 12:263. 2012
    ..We assessed the predictive value of these factors with respect to binge drinking in German adolescents, including the identification of influence direction...
  35. doi request reprint Hippocampal volume loss in patients with alcoholism is influenced by the consumed type of alcoholic beverage
    Julia Wilhelm
    Department of Psychiatry and Psychotherapy, University of Erlangen Nuremberg, Schwabachanlage 6, D 91054 Erlangen, Germany
    Alcohol Alcohol 43:296-9. 2008
    ..Aim of the present study was to investigate different types of alcoholic beverages with regard to hippocampal volume loss in patients suffering from alcoholism...
  36. ncbi request reprint Alcoholism and homicide with respect to the classification systems of Lesch and Cloninger
    Udo Reulbach
    Department of Psychiatry and Psychotherapy, University of Erlangen Nuremberg Germany Schwabachanlage 6, 91054 Erlangen, Germany
    Alcohol Alcohol 42:103-7. 2007
    ..A psychopathological subtyping of alcohol dependence in offenders who committed homicide has mainly been related to impulsive and dissocial personalities up to now...
  37. ncbi request reprint Recurrent detoxifications are associated with craving in patients classified as type 1 according to Lesch's typology
    Thomas Hillemacher
    Department of Psychiatry and Psychotherapy, University of Erlangen Nuremberg, Schwabachanlage 6, D 91054 Erlangen, Germany
    Alcohol Alcohol 41:66-9. 2006
    ..The aim of this investigation was to study the influence of preceding detoxifications on craving in patients with alcoholism classified according to Lesch's typology...
  38. ncbi request reprint Combinations of carbohydrate-deficient transferrin, mean corpuscular erythrocyte volume, gamma-glutamyltransferase, homocysteine and folate increase the significance of biological markers in alcohol dependent patients
    Daniela Rinck
    Department of Psychiatry and Psychotherapy, University of Erlangen Nuremberg, Germany
    Drug Alcohol Depend 89:60-5. 2007
    ..This study focuses on the combination of established laboratory parameters with new meaningful biomarkers to advance the significance regarding alcohol dependence...
  39. ncbi request reprint Elevated alpha synuclein mRNA levels are associated with craving in patients with alcoholism
    Dominikus Bönsch
    Department of Psychiatry and Psychotherapy, Friedrich Alexander University of Erlangen Nuremberg, 91054 Erlangen, Germany
    Biol Psychiatry 56:984-6. 2004
    ..Alpha synuclein has been found elevated in dopamine neurons of cocaine abusers and in rats whose alcohol preference is inbred...
  40. ncbi request reprint Evidence of increased homocysteine levels in alcoholism: the Franconian alcoholism research studies (FARS)
    Stefan Bleich
    Friedrich Alexander University of Erlangen Nuremberg, Department of Psychiatry and Psychotherapy, Schwabachanlage 6, 91054 Erlangen, Germany
    Alcohol Clin Exp Res 29:334-6. 2005
    ..Therefore, this power analysis-based study was undertaken to determine whether plasma homocysteine levels are evidently altered in actively drinking alcoholic patients and patients with early abstinence...
  41. ncbi request reprint Alteration of prolactin serum levels during alcohol withdrawal correlates with craving in female patients
    Thomas Hillemacher
    Department of Psychiatry and Psychotherapy, University of Erlangen Nuremberg, Germany
    Addict Biol 10:337-43. 2005
    ....
  42. ncbi request reprint Alcoholism-associated hyperhomocysteinemia and previous withdrawal seizures
    Kristina Bayerlein
    Department of Psychiatry and Psychotherapy, Friedrich Alexander University of Erlangen Nuremberg, Erlangen, Germany
    Biol Psychiatry 57:1590-3. 2005
    ....
  43. ncbi request reprint Neuroendocrine pathways in benzodiazepine dependence: new targets for research and therapy
    Annemarie Heberlein
    Department of Psychiatry and Psychotherapy, University Hospital Erlangen, Germany
    Hum Psychopharmacol 23:171-81. 2008
    ..Depending on the available results possible implications of NPY and CCK on benzodiazepine addiction and withdrawal symptoms are reviewed, thereby providing topics for further research...
  44. doi request reprint Epigenetic down regulation of nerve growth factor during alcohol withdrawal
    Annemarie Heberlein
    Center for Addiction Research, Department of Psychiatry, Social Psychiatry and Psychotherapy, Medical School Hanover, Carl Neuberg Strase 1, Hannover, Germany
    Addict Biol 18:508-10. 2013
    ..001). The NGF serum levels were significantly associated with the mean methylation of the investigated CpG-sites (F = 1.55, P < 0.001). These results imply an epigenetic regulation of the NGF gene during alcohol withdrawal...
  45. doi request reprint Smoking behaviour is associated with expression and phosphorylation of CREB in human buffy coat
    Bernd Lenz
    Department of Psychiatry and Psychotherapy, Friedrich Alexander University of Erlangen Nuremberg, Germany
    Int J Neuropsychopharmacol 13:207-15. 2010
    ..This kind of study may be helpful for translating findings from animal models and cell cultures...
  46. doi request reprint Microstructural abnormalities of the posterior thalamic radiation and the mediodorsal thalamic nuclei in females with anorexia nervosa--a voxel based diffusion tensor imaging (DTI) study
    Helge Frieling
    Department of Psychiatry, Social Psychiatry and Psychotherapy, Hannover Medical School, Hannover, Germany
    J Psychiatr Res 46:1237-42. 2012
    ....
  47. ncbi request reprint BDNF plasma levels decrease during benzodiazepine withdrawal in patients suffering from comorbidity of depressive disorder and benzodiazepine dependence
    Annemarie Heberlein
    Department of Psychiatry and Psychotherapy, Friedrich Alexander University of Erlangen Nuremberg, Erlangen, Germany
    Psychopharmacology (Berl) 209:213-5. 2010
    ..CONCLUSION: In conclusion, we assume that benzodiazepines may partly act by similar neurobiological mechanisms like antidepressant medication, which may explain the high frequency of benzodiazepine dependence in affective disorders...
  48. doi request reprint Global DNA methylation is influenced by smoking behaviour
    Thomas Hillemacher
    Department of Psychiatry and Psychotherapy, University Hospital Erlangen, Erlangen, Germany
    Eur Neuropsychopharmacol 18:295-8. 2008
    ..68, p=0.02) and completely vanished if the offspring smoked or had ever smoked. These findings suggest an association between smoking behaviour and global DNA methylation, which may be of importance for a wide range of diseases...
  49. ncbi request reprint Association of catecholamine-O-methyltransferase and 5-HTTLPR genotype with eating disorder-related behavior and attitudes in females with eating disorders
    Helge Frieling
    Department of Psychiatry and Psychotherapy, University Erlangen Nuremberg, Erlangen, Germany
    Psychiatr Genet 16:205-8. 2006
    ..The aim of the present study was to evaluate, whether behavioral and attitudinal traits of the disorders can serve as phenotypes with a possible association with two common functional polymorphisms of the monoaminergic pathways...
  50. pmc Alcohol consumption and binge drinking in adolescents: comparison of different migration backgrounds and rural vs. urban residence--a representative study
    Carolin Donath
    Department Medical Psychology and Medical Sociology, Psychiatric University Clinic Erlangen, Schwabachanlage 6, 91054 Erlangen, Germany
    BMC Public Health 11:84. 2011
    ..The aims of the study are the investigation of alcohol consumption patterns with respect to a) urban-rural differences and b) differences according to migration background...
  51. ncbi request reprint Treating dopamimetic psychosis in Parkinson's disease: structured review and meta-analysis
    Helge Frieling
    Department of Psychiatry and Psychotherapy, Friedrich Alexander University Erlangen Nuremberg, Schwabachanlage 6, 91054 Erlangen, Germany
    Eur Neuropsychopharmacol 17:165-71. 2007
    ..Based on randomized trial-derived evidence which is currently available, only clozapine can be fully recommended for the treatment of DIP in PD. Olanzapine should not be used in this indication...
  52. ncbi request reprint Homocysteine levels in patients classified according to Lesch's typology
    Stefan Bleich
    Friedrich Alexander, University of Erlangen Nuremberg, Department of Psychiatry and Psychotherapy, Schwabachanlage 6, D 91054 Erlangen, Germany
    Alcohol Alcohol 39:493-8. 2004
    ..Patients were classified in Lesch's typology (LT) and were divided into two groups: LT 1 (n = 27) and LT 2-4 (n = 117). Within the groups, patients with or without a history of alcohol withdrawal seizures were differentiated...
  53. ncbi request reprint Androgen receptor polyglutamine length does not influence serum levels of adipocytokines in alcoholism: a preliminary retrospective analysis
    Bernd Lenz
    corresponding author
    Alcohol Alcohol 46:214-6. 2011
    ..The aim of the present preliminary retrospective study was to further elucidate whether adiponectin and resistin serum levels are regulated by this AR polymorphism as well...
  54. ncbi request reprint Is parenting style a predictor of suicide attempts in a representative sample of adolescents?
    Carolin Donath
    Center for Health Services Research in Medicine, Department of Psychiatry and Psychotherapy, Friedrich Alexander Universitat Erlangen Nurnberg, Schwabachanlage 6, Erlangen, 91054, Germany
    BMC Pediatr 14:113. 2014
    ....
  55. ncbi request reprint Depression and bulbar involvement in amyotrophic lateral sclerosis
    Thomas Hillemacher
    Department of Psychiatry and Psychotherapy, Centre of Neuromuscular Diseases, University of Erlangen Nuremberg, Germany
    Amyotroph Lateral Scler Other Motor Neuron Disord 5:245-9. 2004
    ..Patients with amyotrophic lateral sclerosis (ALS) often develop depressive symptoms. Little is known of the factors that predict or influence depression in ALS patients...
  56. ncbi request reprint Subjective experience and coping in ALS
    Martin Hecht
    Department of Neurology, Centre of Neuromuscular Diseases, University of Erlangen Nuremberg, Schwabachanlage 6, D 91054 Erlangen, Germany
    Amyotroph Lateral Scler Other Motor Neuron Disord 3:225-31. 2002
    ..Amyotrophic lateral sclerosis is a rapidly progressive and fatal disease which has no known cure and limited symptomatic treatment. While coping strategies in more common diseases are widely assessed, coping is poorly understood in ALS...
  57. ncbi request reprint Alcoholism, craving, and hormones: the role of leptin, ghrelin, prolactin, and the pro-opiomelanocortin system in modulating ethanol intake
    Friedrich Martin Wurst
    Christian Doppler Clinic, Department of Psychiatry and Psychotherapy II Addiction Medicine, Paracelsus Medical University, Salzburg, Austria
    Alcohol Clin Exp Res 31:1963-7. 2007
    ..The goal of this mini-review is to discuss the results of some recent investigations of the potential interactions of these systems with acute and chronic alcohol responses...
  58. ncbi request reprint Limited use of CK-MB as a screening parameter for acute coronary syndrome in patients with alcohol dependency
    Julia Wilhelm
    J Stud Alcohol 66:577-8. 2005
  59. ncbi request reprint Genetic predisposition to neuroleptic malignant syndrome in siblings
    Marc Ziegenbein
    Ann Pharmacother 40:574-5. 2006
  60. ncbi request reprint Homocysteine and epigenetic DNA methylation: a biological model for depression?
    Thomas Hillemacher
    Am J Psychiatry 164:1610. 2007
  61. ncbi request reprint Extensive craving in high dose zolpidem dependency
    Jana Svitek
    Prog Neuropsychopharmacol Biol Psychiatry 32:591-2. 2008
  62. ncbi request reprint Ketamine for the treatment of depression: what about the addictive potential?
    Thomas Hillemacher
    Aust N Z J Psychiatry 41:772-3. 2007
  63. ncbi request reprint Elevated prenatal homocysteine levels and the risk of schizophrenia
    Stefan Bleich
    Arch Gen Psychiatry 64:980-1. 2007
  64. ncbi request reprint Obsessive-compulsive alcohol craving is not associated with Apolipoprotein E genotype
    Thomas Hillemacher
    Psychiatr Genet 16:231-2. 2006
    ..Statistical analysis revealed no significant association between Apolipoprotein E polymorphism and obsessive-compulsive alcohol craving (analysis of variance: F=1.11, P=0.358)...