Martin Herrmann

Summary

Affiliation: University of Erlangen-Nuremberg
Country: Germany

Publications

  1. pmc T cells as key players for bone destruction in gouty arthritis?
    Ulrike Harre
    Arthritis Res Ther 13:135. 2011
  2. pmc Bonding the foe - NETting neutrophils immobilize the pro-inflammatory monosodium urate crystals
    Christine Schorn
    Institute for Clinical Immunology and Rheumatology, Department of Internal Medicine III, University of Erlangen Nuremberg Erlangen, Germany
    Front Immunol 3:376. 2012
  3. pmc Monosodium urate crystals induce extracellular DNA traps in neutrophils, eosinophils, and basophils but not in mononuclear cells
    Christine Schorn
    Department of Internal Medicine 3, Institute for Clinical Immunology, Friedrich Alexander University Erlangen Nuremberg Erlangen, Germany
    Front Immunol 3:277. 2012
  4. pmc Phagocytosis and LPS alter the maturation state of β-amyloid precursor protein and induce different Aβ peptide release signatures in human mononuclear phagocytes
    Philipp Spitzer
    Department of Psychiatry and Psychotherapy, University of Erlangen Nuremberg, Schwabachanlage 6, D 91054 Erlangen, Germany
    J Neuroinflammation 7:59. 2010
  5. pmc Sodium overload and water influx activate the NALP3 inflammasome
    Christine Schorn
    Department of Internal Medicine 3, University of Erlangen Nuremberg, 91054 Erlangen, Germany
    J Biol Chem 286:35-41. 2011
  6. ncbi request reprint Aggregated neutrophil extracellular traps limit inflammation by degrading cytokines and chemokines
    Christine Schauer
    Department of Internal Medicine 3, University of Erlangen Nuremberg, Erlangen, Germany
    Nat Med 20:511-7. 2014
  7. doi request reprint Detection of low level cryoglobulins by flow cytometry
    Rüdiger B Müller
    Department of Internal Medicine 3, University of Erlangen Nurnberg, Krankenhausstrasse 12, D 91054 Erlangen, Germany
    Cytometry A 81:883-7. 2012
  8. doi request reprint Autoantibodies against galectins are associated with antiphospholipid syndrome in patients with systemic lupus erythematosus
    Kerstin Sarter
    Department of Internal Medicine 3, Friedrich Alexander University Erlangen Nuremberg, Germany
    Glycobiology 23:12-22. 2013
  9. pmc Magnetic drug targeting reduces the chemotherapeutic burden on circulating leukocytes
    Christina Janko
    Department of Internal Medicine 3, Friedrich Alexander University Erlangen Nuremberg, Ulmenweg 18, Erlangen 91054, Germany
    Int J Mol Sci 14:7341-55. 2013
  10. pmc CRP/anti-CRP Antibodies Assembly on the Surfaces of Cell Remnants Switches Their Phagocytic Clearance Toward Inflammation
    Christina Janko
    Department of Internal Medicine 3, Friedrich Alexander University Erlangen Nuremberg Erlangen, Germany
    Front Immunol 2:70. 2011

Collaborators

Detail Information

Publications17

  1. pmc T cells as key players for bone destruction in gouty arthritis?
    Ulrike Harre
    Arthritis Res Ther 13:135. 2011
    ..In vitro stimulation with MSU crystals revealed monocytes as a source for these cytokines, whereas T cells produce RANKL, the major trigger of osteoclastogenesis...
  2. pmc Bonding the foe - NETting neutrophils immobilize the pro-inflammatory monosodium urate crystals
    Christine Schorn
    Institute for Clinical Immunology and Rheumatology, Department of Internal Medicine III, University of Erlangen Nuremberg Erlangen, Germany
    Front Immunol 3:376. 2012
    ....
  3. pmc Monosodium urate crystals induce extracellular DNA traps in neutrophils, eosinophils, and basophils but not in mononuclear cells
    Christine Schorn
    Department of Internal Medicine 3, Institute for Clinical Immunology, Friedrich Alexander University Erlangen Nuremberg Erlangen, Germany
    Front Immunol 3:277. 2012
    ..Our data show that MSU crystals induce extracellular DNA trap formation in all three granulocytes lineages (NETs, EETs, and BETs) but not in monocytes, and DNA externalization does not necessitate the uptake of the crystals...
  4. pmc Phagocytosis and LPS alter the maturation state of β-amyloid precursor protein and induce different Aβ peptide release signatures in human mononuclear phagocytes
    Philipp Spitzer
    Department of Psychiatry and Psychotherapy, University of Erlangen Nuremberg, Schwabachanlage 6, D 91054 Erlangen, Germany
    J Neuroinflammation 7:59. 2010
    ..Similarly, cerebrovascular β-amyloid (Aβ) deposits are surrounded by perivascular macrophages. Both observations indicate a contribution of the mononuclear phagocyte system to the development of β-amyloid...
  5. pmc Sodium overload and water influx activate the NALP3 inflammasome
    Christine Schorn
    Department of Internal Medicine 3, University of Erlangen Nuremberg, 91054 Erlangen, Germany
    J Biol Chem 286:35-41. 2011
    ..As a translational aspect one may consider the use of chloroquine for the anti-inflammatory treatment of refractory gout...
  6. ncbi request reprint Aggregated neutrophil extracellular traps limit inflammation by degrading cytokines and chemokines
    Christine Schauer
    Department of Internal Medicine 3, University of Erlangen Nuremberg, Erlangen, Germany
    Nat Med 20:511-7. 2014
    ..These findings suggest that aggregated NETs promote the resolution of neutrophilic inflammation by degrading cytokines and chemokines and disrupting neutrophil recruitment and activation. ..
  7. doi request reprint Detection of low level cryoglobulins by flow cytometry
    Rüdiger B Müller
    Department of Internal Medicine 3, University of Erlangen Nurnberg, Krankenhausstrasse 12, D 91054 Erlangen, Germany
    Cytometry A 81:883-7. 2012
    ..No small diffracting particles were detected in the sera of the 33 healthy controls. Flow cytometry is equally specific but much more sensitive in the detection of CG than visual inspection...
  8. doi request reprint Autoantibodies against galectins are associated with antiphospholipid syndrome in patients with systemic lupus erythematosus
    Kerstin Sarter
    Department of Internal Medicine 3, Friedrich Alexander University Erlangen Nuremberg, Germany
    Glycobiology 23:12-22. 2013
    ..Equally of note, the presence of IgG autoantibodies against galectins capable to act as an opsonin may contribute to a sustained immune dysregulation in patients with chronic inflammatory rheumatic diseases...
  9. pmc Magnetic drug targeting reduces the chemotherapeutic burden on circulating leukocytes
    Christina Janko
    Department of Internal Medicine 3, Friedrich Alexander University Erlangen Nuremberg, Ulmenweg 18, Erlangen 91054, Germany
    Int J Mol Sci 14:7341-55. 2013
    ..We demonstrated that MDT spares the immune system in comparison with conventional chemotherapy...
  10. pmc CRP/anti-CRP Antibodies Assembly on the Surfaces of Cell Remnants Switches Their Phagocytic Clearance Toward Inflammation
    Christina Janko
    Department of Internal Medicine 3, Friedrich Alexander University Erlangen Nuremberg Erlangen, Germany
    Front Immunol 2:70. 2011
    ..In conclusion, anti-CRP, CRP, and SNEC form a ternary pyrogen endowed with strong pro-inflammatory capabilities which is able to maintain and perpetuate chronic inflammation...
  11. doi request reprint High frequency of autoantibody-secreting cells and long-lived plasma cells within inflamed kidneys of NZB/W F1 lupus mice
    Charlotte Starke
    Department of Internal Medicine 3, Clinical Research Group, Nikolaus Fiebiger Center of Molecular Medicine, University of Erlangen Nuremberg, Erlangen, Germany
    Eur J Immunol 41:2107-12. 2011
    ..Moreover, the frequencies of IgG-secreting cells specific for the autoantigens dsDNA and nucleolin were higher in the kidneys compared with those in the spleen and bone marrow...
  12. ncbi request reprint Sodium and potassium urate crystals differ in their inflammatory potential
    Christine Schorn
    Department for Internal Medicine 3, Institute for Clinical Immunology, Friedrich Alexander University of Erlangen Nurnberg, Erlangen, Germany
    Autoimmunity 42:314-6. 2009
    ..These results show that the cation of urate crystals determines the response of innate immune cells, indicating that the micromilieu at the site of crystal formation is important for their inflammatory potential...
  13. doi request reprint 12/15-lipoxygenase orchestrates the clearance of apoptotic cells and maintains immunologic tolerance
    Stefan Uderhardt
    Department of Internal Medicine 3 and Institute for Clinical Immunology, University of Erlangen Nuremberg, 91054 Erlangen, Germany
    Immunity 36:834-46. 2012
    ..Our data reveal an unexpected key role for enzymatic lipid oxidation during the maintenance of self-tolerance...
  14. doi request reprint The role of somatic hypermutation in the generation of pathogenic antibodies in SLE
    Kristin Schroeder
    Department of Internal Medicine 3, Institute for Clinical Immunology, University of Erlangen Nuremberg, Erlangen, Germany
    Autoimmunity 46:121-7. 2013
    ..This review summarizes the proposed mechanisms for the generation of anti-dsDNA in murine lupus and in SLE patients...
  15. ncbi request reprint Role of apoptosis failure in etiopathogenesis of systemic lupus erythematosus and murine lupus
    Kerstin Sarter
    Department for Internal Medicine 3, Institute for Clinical Immunology, , Germany
    Expert Rev Clin Immunol 4:33-42. 2008
    ..For an efficient therapy of systemic lupus erythematosus, it is necessary to analyze apoptosis and clearance defects and to unravel factors leading to its onset...
  16. doi request reprint Scent of dying cells: the role of attraction signals in the clearance of apoptotic cells and its immunological consequences
    Luis E Munoz
    Institute for Clinical Immunology, Department for Internal Medicine 3, University Hospital Erlangen, Germany
    Autoimmun Rev 9:425-30. 2010
    ....
  17. doi request reprint Autoimmunity and chronic inflammation - two clearance-related steps in the etiopathogenesis of SLE
    Luis E Munoz
    Department for Internal Medicine 3, University Hospital Erlangen, Friedrich Alexander University of Erlangen Nuremberg, 91054 Erlangen, Germany
    Autoimmun Rev 10:38-42. 2010
    ..Chronic inflammation in SLE is consequently promoted by the persistently binding of AAb with their cognate autoantigens forming a binary weapon: the nucleic acid-containing IC...