Joachim Hermisson

Summary

Affiliation: University of Munich
Country: Germany

Publications

  1. pmc Soft sweeps: molecular population genetics of adaptation from standing genetic variation
    Joachim Hermisson
    Section of Evolutionary Biology, Department of Biology II, Ludwig Maximilians University Munich, Germany
    Genetics 169:2335-52. 2005
  2. doi request reprint An analytically tractable model for competitive speciation
    Pleuni S Pennings
    Section of Evolutionary Biology, Department of Biology II, Ludwig Maximilians University Munich, Grosshaderner Strasse 2, D 82152 Planegg Martinsried, Germany
    Am Nat 171:E44-71. 2008
  3. pmc Adaptation of a quantitative trait to a moving optimum
    Michael Kopp
    Section of Evolutionary Biology, Department Biology II, Ludwig Maximilian University, Munich, Germany
    Genetics 176:715-9. 2007
  4. pmc Soft sweeps III: the signature of positive selection from recurrent mutation
    Pleuni S Pennings
    Section of Evolutionary Biology, Department Biology II, Ludwig Maximilians University Munich, Planegg Martinsried, Germany
    PLoS Genet 2:e186. 2006
  5. ncbi request reprint Soft sweeps II--molecular population genetics of adaptation from recurrent mutation or migration
    Pleuni S Pennings
    Section of Evolutionary Biology, Department of Biology II, Ludwig Maximilians University Munich, Planegg Martinsried, Germany
    Mol Biol Evol 23:1076-84. 2006
  6. ncbi request reprint The evolution of genetic architecture under frequency-dependent disruptive selection
    Michael Kopp
    Section of Evolutionary Biology, Department of Biology II, Ludwig Maximilian University Munich, Grosshadernerstrasse 2, 82152 Martinsried, Germany
    Evolution 60:1537-50. 2006
  7. pmc The population genetic theory of hidden variation and genetic robustness
    Joachim Hermisson
    Section of Evolutionary Biology, Department of Biology II, Ludwig Maximilians University Munich, D 82152 Planegg, Germany
    Genetics 168:2271-84. 2004
  8. ncbi request reprint A dissection of volatility in yeast
    Nina Stoletzki
    Section of Evolutionary Biology, Department Biology II, Ludwig Maximilians University Munich, Planegg Martinsried, Germany
    Mol Biol Evol 22:2022-6. 2005
  9. ncbi request reprint Evolution of genetic architecture under directional selection
    Thomas F Hansen
    Centre for Ecological and Evolutionary Synthesis, Department of Biology, University of Oslo, 0316 Oslo, Norway
    Evolution 60:1523-36. 2006
  10. ncbi request reprint The role of epistatic gene interactions in the response to selection and the evolution of evolvability
    Ashley J R Carter
    Florida State University, Department of Biological Sciences, Conradi Building, Tallahassee, FL 32306, USA
    Theor Popul Biol 68:179-96. 2005

Detail Information

Publications14

  1. pmc Soft sweeps: molecular population genetics of adaptation from standing genetic variation
    Joachim Hermisson
    Section of Evolutionary Biology, Department of Biology II, Ludwig Maximilians University Munich, Germany
    Genetics 169:2335-52. 2005
    ..We find that soft sweeps with weaker selective footprints are likely under both scenarios if the mutation rate and/or the selection coefficient is high...
  2. doi request reprint An analytically tractable model for competitive speciation
    Pleuni S Pennings
    Section of Evolutionary Biology, Department of Biology II, Ludwig Maximilians University Munich, Grosshaderner Strasse 2, D 82152 Planegg Martinsried, Germany
    Am Nat 171:E44-71. 2008
    ..The results demonstrate how even in a simple model, the evolutionary outcome depends in a complex way on ecological and genetic parameters...
  3. pmc Adaptation of a quantitative trait to a moving optimum
    Michael Kopp
    Section of Evolutionary Biology, Department Biology II, Ludwig Maximilian University, Munich, Germany
    Genetics 176:715-9. 2007
    ..If the environment is rate limiting, mutations with a small phenotypic effect are preferred over large mutations, in contrast to standard theory...
  4. pmc Soft sweeps III: the signature of positive selection from recurrent mutation
    Pleuni S Pennings
    Section of Evolutionary Biology, Department Biology II, Ludwig Maximilians University Munich, Planegg Martinsried, Germany
    PLoS Genet 2:e186. 2006
    ..In contrast, for levels of LD, the signature is even stronger if recurrent beneficial mutation plays a role. We suggest a variant of existing LD tests that increases their power to detect this signature...
  5. ncbi request reprint Soft sweeps II--molecular population genetics of adaptation from recurrent mutation or migration
    Pleuni S Pennings
    Section of Evolutionary Biology, Department of Biology II, Ludwig Maximilians University Munich, Planegg Martinsried, Germany
    Mol Biol Evol 23:1076-84. 2006
    ..We find that so-called "soft sweeps," where multiple ancestral haplotypes appear in a sample, are likely for biologically realistic values of mutation or migration rates...
  6. ncbi request reprint The evolution of genetic architecture under frequency-dependent disruptive selection
    Michael Kopp
    Section of Evolutionary Biology, Department of Biology II, Ludwig Maximilian University Munich, Grosshadernerstrasse 2, 82152 Martinsried, Germany
    Evolution 60:1537-50. 2006
    ..As such, it should be seen as a potential evolutionary pathway to discrete polymorphisms and as a potential alternative to other evolutionary responses, such as the evolution of sexual dimorphism or assortative mating...
  7. pmc The population genetic theory of hidden variation and genetic robustness
    Joachim Hermisson
    Section of Evolutionary Biology, Department of Biology II, Ludwig Maximilians University Munich, D 82152 Planegg, Germany
    Genetics 168:2271-84. 2004
    ..We conclude that the release of hidden genetic variance due to a major mutation or environmental stress does not demonstrate canalization of the wild-type genotype...
  8. ncbi request reprint A dissection of volatility in yeast
    Nina Stoletzki
    Section of Evolutionary Biology, Department Biology II, Ludwig Maximilians University Munich, Planegg Martinsried, Germany
    Mol Biol Evol 22:2022-6. 2005
    ....
  9. ncbi request reprint Evolution of genetic architecture under directional selection
    Thomas F Hansen
    Centre for Ecological and Evolutionary Synthesis, Department of Biology, University of Oslo, 0316 Oslo, Norway
    Evolution 60:1523-36. 2006
    ....
  10. ncbi request reprint The role of epistatic gene interactions in the response to selection and the evolution of evolvability
    Ashley J R Carter
    Florida State University, Department of Biological Sciences, Conradi Building, Tallahassee, FL 32306, USA
    Theor Popul Biol 68:179-96. 2005
    ..The build-up of linkage disequilibrium also has negligible effects. We argue that directional epistasis is likely to have major effects on evolutionary dynamics and should be the focus of empirical studies of epistasis...
  11. ncbi request reprint Effects of epistasis on phenotypic robustness in metabolic pathways
    Homayoun Bagheri-Chaichian
    Santa Fe Institute, 1399 Hyde Park Road, Santa Fe, NM 87501, USA
    Math Biosci 184:27-51. 2003
    ..In such cases dominance levels can be modified by mutations that affect saturation levels. The implication is that dominance is not a necessary property of metabolic systems and that it can be subject to evolutionary modification...
  12. ncbi request reprint Perspective: Evolution and detection of genetic robustness
    J Arjan G M de Visser
    Department of Genetics, Wageningen University, Arboretumlaan 4, 6703 BD Wageningen, The Netherlands
    Evolution 57:1959-72. 2003
    ....
  13. ncbi request reprint Epistasis in polygenic traits and the evolution of genetic architecture under stabilizing selection
    Joachim Hermisson
    Department of Ecology and Evolutionary Biology, Yale University, P O Box 208106, New Haven, Connecticut 06520 8106, USA
    Am Nat 161:708-34. 2003
    ..Here, primarily genes with a high mutation rate are buffered, often at the cost of decanalization of other genes. An intuitive interpretation of this view is given in the discussion...
  14. ncbi request reprint Mutation-selection balance: ancestry, load, and maximum principle
    Joachim Hermisson
    Department of Ecology and Evolutionary Biology, Yale University, New Haven, Connecticut 06520, USA
    Theor Popul Biol 62:9-46. 2002
    ..These results are applied to threshold phenomena caused by the interplay of selection and mutation (known as error thresholds). They lead to a clarification of concepts, as well as criteria for the existence of error thresholds...