Corinna Hermann

Summary

Affiliation: University of Konstanz
Country: Germany

Publications

  1. ncbi request reprint Review: variability of host-pathogen interaction
    Corinna Hermann
    Biochemical Pharmacology, University of Konstanz, Konstanz, Germany
    J Endotoxin Res 13:199-218. 2007
  2. pmc Comparison of quantitative and semiquantitative enzyme-linked immunosorbent assays for immunoglobulin G against Chlamydophila pneumoniae to a microimmunofluorescence test for use with patients with respiratory tract infections
    Corinna Hermann
    Biochemical Pharmacology, University of Konstanz, 78457 Constance, Germany
    J Clin Microbiol 42:2476-9. 2004
  3. ncbi request reprint Endogenous cortisol determines the circadian rhythm of lipopolysaccharide-- but not lipoteichoic acid--inducible cytokine release
    Corinna Hermann
    Biochemical Pharmacology, University of Konstanz, D 78457 Konstanz, Germany
    Eur J Immunol 36:371-9. 2006
  4. doi request reprint Cytokine induction by Gram-positive bacteria
    Christian Draing
    Biochemical Pharmacology, University of Konstanz, 78457 Konstanz, Germany
    Immunobiology 213:285-96. 2008
  5. pmc Heterozygous toll-like receptor 2 polymorphism does not affect lipoteichoic acid-induced chemokine and inflammatory responses
    Sonja von Aulock
    Biochemical Pharmacology, University of Konstanz, 78457 Konstanz, Germany
    Infect Immun 72:1828-31. 2004
  6. doi request reprint IL-10 release requires stronger toll-like receptor 4-triggering than TNF: a possible explanation for the selective effects of heterozygous TLR4 polymorphism Asp(299)Gly on IL-10 release
    Oliver Dehus
    Biochemical Pharmacology, University of Konstanz, P O Box M668, 78457 Konstanz, Germany
    Immunobiology 213:621-7. 2008
  7. ncbi request reprint Heterozygous toll-like receptor 4 polymorphism does not influence lipopolysaccharide-induced cytokine release in human whole blood
    Sonja von Aulock
    Biochemical Pharmacology, University of Konstanz, Konstanz, Germany
    J Infect Dis 188:938-43. 2003
  8. ncbi request reprint Immunoproteomic identification and serological responses to novel Chlamydia pneumoniae antigens that are associated with persistent C. pneumoniae infections
    Sebastian Bunk
    Department of Biochemical Pharmacology, University of Konstanz, Konstanz, Germany
    J Immunol 180:5490-8. 2008
  9. pmc Chlamydia pneumoniae-induced memory CD4+ T-cell activation in human peripheral blood correlates with distinct antibody response patterns
    Sebastian Bunk
    Department of Biochemical Pharmacology, University of Konstanz, Konstanz, Germany
    Clin Vaccine Immunol 17:705-12. 2010
  10. ncbi request reprint Gender difference in cytokine secretion on immune stimulation with LPS and LTA
    Sonja von Aulock
    Biochemical Pharmacology, University of Konstanz, Germany
    J Interferon Cytokine Res 26:887-92. 2006

Collaborators

Detail Information

Publications32

  1. ncbi request reprint Review: variability of host-pathogen interaction
    Corinna Hermann
    Biochemical Pharmacology, University of Konstanz, Konstanz, Germany
    J Endotoxin Res 13:199-218. 2007
    ..The emerging, more complex, view of the factors determining course and outcome of infections promises to enable more tailored and thus, hopefully, more effective treatment decisions...
  2. pmc Comparison of quantitative and semiquantitative enzyme-linked immunosorbent assays for immunoglobulin G against Chlamydophila pneumoniae to a microimmunofluorescence test for use with patients with respiratory tract infections
    Corinna Hermann
    Biochemical Pharmacology, University of Konstanz, 78457 Constance, Germany
    J Clin Microbiol 42:2476-9. 2004
    ..These results show that ELISAs that are fast and objective deliver seroprevalence results, sensitivities, and specificities that are very similar to those of the MIF test...
  3. ncbi request reprint Endogenous cortisol determines the circadian rhythm of lipopolysaccharide-- but not lipoteichoic acid--inducible cytokine release
    Corinna Hermann
    Biochemical Pharmacology, University of Konstanz, D 78457 Konstanz, Germany
    Eur J Immunol 36:371-9. 2006
    ..Furthermore, 10-50-fold higher HC concentrations as compared to LPS were required to block LTA-induced cytokine release. LTA, in contrast to LPS, failed to activate Jun kinase, a reported target for HC action...
  4. doi request reprint Cytokine induction by Gram-positive bacteria
    Christian Draing
    Biochemical Pharmacology, University of Konstanz, 78457 Konstanz, Germany
    Immunobiology 213:285-96. 2008
    ..The purification and characterization of the respective components of the bacterial cell wall has begun...
  5. pmc Heterozygous toll-like receptor 2 polymorphism does not affect lipoteichoic acid-induced chemokine and inflammatory responses
    Sonja von Aulock
    Biochemical Pharmacology, University of Konstanz, 78457 Konstanz, Germany
    Infect Immun 72:1828-31. 2004
    ..Blood from heterozygous polymorphic and wild-type donors reacted uniformly to LTA and Staphylococcus aureus. Thus, one functional allele for Toll-like receptor 2 suffices for full cytokine response...
  6. doi request reprint IL-10 release requires stronger toll-like receptor 4-triggering than TNF: a possible explanation for the selective effects of heterozygous TLR4 polymorphism Asp(299)Gly on IL-10 release
    Oliver Dehus
    Biochemical Pharmacology, University of Konstanz, P O Box M668, 78457 Konstanz, Germany
    Immunobiology 213:621-7. 2008
    ..The lower number of responsive wild-type TLR4 receptors on monocytes of heterozygotes may explain why only IL-10 release is affected...
  7. ncbi request reprint Heterozygous toll-like receptor 4 polymorphism does not influence lipopolysaccharide-induced cytokine release in human whole blood
    Sonja von Aulock
    Biochemical Pharmacology, University of Konstanz, Konstanz, Germany
    J Infect Dis 188:938-43. 2003
    ..These data demonstrate that the heterozygous Asp299Gly polymorphism does not exhibit a functional defect in cytokine release after the stimulation of blood monocytes...
  8. ncbi request reprint Immunoproteomic identification and serological responses to novel Chlamydia pneumoniae antigens that are associated with persistent C. pneumoniae infections
    Sebastian Bunk
    Department of Biochemical Pharmacology, University of Konstanz, Konstanz, Germany
    J Immunol 180:5490-8. 2008
    ..pneumoniae in vitro. Our data provide the first evidence of a unique Ab-response pattern associated with persistent C. pneumoniae infections, which is a prerequisite for the serological determination of persistently infected patients...
  9. pmc Chlamydia pneumoniae-induced memory CD4+ T-cell activation in human peripheral blood correlates with distinct antibody response patterns
    Sebastian Bunk
    Department of Biochemical Pharmacology, University of Konstanz, Konstanz, Germany
    Clin Vaccine Immunol 17:705-12. 2010
    ..pneumoniae antigens...
  10. ncbi request reprint Gender difference in cytokine secretion on immune stimulation with LPS and LTA
    Sonja von Aulock
    Biochemical Pharmacology, University of Konstanz, Germany
    J Interferon Cytokine Res 26:887-92. 2006
    ..Thus, the stronger innate immune response of males in comparison to females appears to stem not only from a difference in monocyte counts but also from the steepness of the response curve...
  11. ncbi request reprint Endotoxin evaluation of eleven lipopolysaccharides by whole blood assay does not always correlate with Limulus amebocyte lysate assay
    Oliver Dehus
    Biochemical Pharmacology, University of Konstanz, Konstanz, Germany
    J Endotoxin Res 12:171-80. 2006
    ..coli. This results in an overestimation of pyrogenic burden by a factor of 500 in the sample when compared with the biological activity of highly purified P. aeruginosa LPS in human whole blood...
  12. doi request reprint Growth temperature-dependent expression of structural variants of Listeria monocytogenes lipoteichoic acid
    Oliver Dehus
    Biochemical Pharmacology, University of Konstanz, Konstanz 78467, Germany
    Immunobiology 216:24-31. 2011
    ..68). The observed shift in LTA expression, probably accompanying the switch from the saprophytic to the virulent entity, indicates an important adaptation to the different structural requirements inside the host cells...
  13. ncbi request reprint Toll-like receptors 2 and 4 do not contribute to clearance of Chlamydophila pneumoniae in mice, but are necessary for the release of monokines
    Markus Mueller
    Biochemical Pharmacology, University of Konstanz, Konstanz 78457, Germany
    Immunobiology 209:599-608. 2004
    ..pneumoniae in the lungs was proven by the efficacy of antibiotic treatment. These findings indicate that in vivo TLR2 and TLR4 are not important for the development of antibodies and elimination of C. pneumoniae...
  14. pmc Critical investigation of the CD14 promoter polymorphism: lack of a role for in vitro cytokine response and membrane CD14 expression
    Sonja von Aulock
    Biochemical Pharmacology, University of Konstanz, P O Box M655, 78457 Konstanz, Germany
    Clin Diagn Lab Immunol 12:1254-6. 2005
    ..An analysis of the published data on the proposed association of CD14 genotype with membrane CD14 density revealed no significant correlation, questioning a functional impact of the CD14 polymorphism...
  15. ncbi request reprint Cytokine induction by purified lipoteichoic acids from various bacterial species--role of LBP, sCD14, CD14 and failure to induce IL-12 and subsequent IFN-gamma release
    Corinna Hermann
    Biochemical Pharmacology, University of Konstanz, D 78457 Konstanz, Germany
    Eur J Immunol 32:541-51. 2002
    ..In conclusion, LTA compared to LPS, are weak inducers of IL-12 and subsequent IFN-gamma formation which might explain their lower toxicity in vivo...
  16. pmc Comparison of eleven commercial tests for Chlamydia pneumoniae-specific immunoglobulin G in asymptomatic healthy individuals
    Corinna Hermann
    Biochemical Pharmacology, University of Konstanz, 78457 Konstanz, Germany
    J Clin Microbiol 40:1603-9. 2002
    ..MIF must still be considered the best method for the detection of IgG in apparently healthy subjects, but the sensitivities and specificities of new ELISAs approximate those of MIFs...
  17. ncbi request reprint A model of human whole blood lymphokine release for in vitro and ex vivo use
    Corinna Hermann
    Biochemical Pharmacology, University of Konstanz, 78457, Constance, Germany
    J Immunol Methods 275:69-79. 2003
    ..The model appears to be suitable for the evaluation of immunomodulatory agents in vitro as well as ex vivo...
  18. doi request reprint Biomarker candidates of Chlamydophila pneumoniae proteins and protein fragments identified by affinity-proteomics using FTICR-MS and LC-MS/MS
    Iuliana Susnea
    Laboratory of Analytical Chemistry and Biopolymer Structure Analysis, Department of Chemistry, University of Konstanz, 78457 Konstanz, Germany
    J Am Soc Mass Spectrom 22:784-8. 2011
    ....
  19. ncbi request reprint MDP and other muropeptides--direct and synergistic effects on the immune system
    Stephanie Traub
    Biochemical Pharmacology, University of Konstanz, Konstanz, Germany
    J Endotoxin Res 12:69-85. 2006
    ..This review discusses the structure and occurrence of muropeptides and gives a broad overview of their inflammatory and adjuvant activity and the possible involvement of receptors in these responses...
  20. ncbi request reprint Structural requirements of synthetic muropeptides to synergize with lipopolysaccharide in cytokine induction
    Stephanie Traub
    Department of Biochemical Pharmacology, University of Konstanz, Konstanz 78457, Germany
    J Biol Chem 279:8694-700. 2004
    ..In conclusion, these data show that nanomolar quantities of muropeptides dramatically potentiate LPS-induced monocyte activation. This has implications for pyrogenicity testing and endotoxemia in patients...
  21. doi request reprint Different Staphylococcus aureus whole bacteria mutated in putative pro-inflammatory membrane components have similar cytokine inducing activity
    Christoph Rockel
    Biochemical Pharmacology, University of Konstanz, Universitätsstr 10, 78464 Konstanz, Germany
    Immunobiology 216:316-21. 2011
    ....
  22. ncbi request reprint Endothelial cells are protected against phagocyte-transmitted Chlamydophila pneumoniae infections by laminar shear stress Gueinzius: Shear stress protects from C. pneumoniae infection
    Katja Gueinzius
    Biochemical Pharmacology, University of Konstanz, 78457 Konstanz, Germany
    Atherosclerosis 198:256-63. 2008
    ..This can explain the focal distribution of C. pneumoniae in the vasculature and links two risk factors of atherosclerosis, i.e. the lack of laminar flow and infection...
  23. ncbi request reprint Determination of the eicosanoid response to inflammatory stimuli in whole blood and its pharmacological modulation ex vivo
    Sonja von Aulock
    Biochemical Pharmacology, University of Konstanz, POB M655, 78457, Konstanz, Germany
    J Immunol Methods 277:53-63. 2003
    ..Furthermore, the assay could be used to characterize the immune status of patient groups or to monitor the course of disease...
  24. pmc Identification of Borrelia burgdorferi ribosomal protein L25 by the phage surface display method and evaluation of the protein's value for serodiagnosis
    Markus Mueller
    University of Konstanz, Biochemical Pharmacology, 78457 Konstanz, Germany
    J Clin Microbiol 44:3778-80. 2006
    ....
  25. pmc Structural decomposition and heterogeneity of commercial lipoteichoic Acid preparations
    Siegfried Morath
    University of Konstanz, Biochemical Pharmacology, Konstanz, Germany
    Infect Immun 70:938-44. 2002
    ..Taken together, these data indicate that these crude preparations with relatively high endotoxin contamination are not suitable for characterizing the activation of immune cells by LTA...
  26. pmc Enhanced antiinflammatory capacity of a Lactobacillus plantarum mutant synthesizing modified teichoic acids
    Corinne Grangette
    Laboratoire de Bactériologie des Ecosytèmes, Institut Pasteur de Lille Institut de Biologie de Lille, 59019 Lille Cedex, France
    Proc Natl Acad Sci U S A 102:10321-6. 2005
    ..The results indicated that composition of LTA within the whole-cell context of L. plantarum can modulate proinflammatory or antiinflammatory immune responses...
  27. ncbi request reprint D-alanyl ester depletion of teichoic acids in Lactobacillus reuteri 100-23 results in impaired colonization of the mouse gastrointestinal tract
    Jens Walter
    Department of Microbiology and Immunology, University of Otago, PO Box 56, Dunedin, New Zealand
    Environ Microbiol 9:1750-60. 2007
    ..This study showed that D-alanylation is an important cell function of L. reuteri that seems to protect this commensal organism against the hostile conditions prevailing in the murine forestomach...
  28. ncbi request reprint Comment on "Not lipoteichoic acid but lipoproteins appear to be the dominant immunobiologically active compounds in Staphylococcus aureus"
    Sonja von Aulock
    J Immunol 178:2610; author reply 2610-1. 2007
  29. pmc Indoleamine 2,3-dioxygenase-expressing dendritic cells form suppurative granulomas following Listeria monocytogenes infection
    Alexey Popov
    Molecular Tumor Biology and Tumor Immunology at the Clinic I for Internal Medicine, University of Cologne, Cologne, Germany
    J Clin Invest 116:3160-70. 2006
    ..These findings place IDO(+) DCs not only at the intersection of innate and adaptive immunity but also at the forefront of bacterial containment in granulomatous infections...
  30. ncbi request reprint Sesquiterpene lactones induce distinct forms of cell death that modulate human monocyte-derived macrophage responses
    Nancy López-Antón
    Department of Pharmacy, Center of Drug Research, University of Munich, Germany
    Apoptosis 12:141-53. 2007
    ..We propose that this type of SQTL may influence local inflammation by transiently activating the immune system and help to clear cells by inducing a form of cell death that promotes phagocytosis...
  31. ncbi request reprint Heterozygous Arg753Gln polymorphism of human TLR-2 impairs immune activation by Borrelia burgdorferi and protects from late stage Lyme disease
    Nicolas W J Schröder
    Institut für Mikrobiologie und Hygiene, Charite University Medical Center, Berlin, Germany
    J Immunol 175:2534-40. 2005
    ..3 vs 12.5%, odds ratio 0.163, 95% confidence interval 0.04-0.76, p = 0.018). These data suggest that Arg753Gln may protect from the development of late stage LD due to a reduced signaling via TLR-2/TLR-1...
  32. pmc Genetically determined susceptibility to tuberculosis in mice causally involves accelerated and enhanced recruitment of granulocytes
    Christine Keller
    Molecular Infection Biology, Research Center Borstel, Parkallee 22, D 23845 Borstel, Germany
    Infect Immun 74:4295-309. 2006
    ..tuberculosis significantly longer than control mice. We conclude that initially enhanced recruitment of granulocytes contributes to susceptibility to tuberculosis...