M Henke

Summary

Affiliation: University of Freiburg
Country: Germany

Publications

  1. ncbi Quantitative and semiquantitative evaluation of erythropoietin-induced bone marrow signal changes in lumbar spine MRI in patients with tumor anemia
    Nadir Ghanem
    Department of Diagnostic Radiology, University Hospital Freiburg, Germany
    Onkologie 30:303-8. 2007
  2. ncbi The effects of tea extracts on proinflammatory signaling
    Frank Pajonk
    Department of Radiation Oncology, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095 1714, USA
    BMC Med 4:28. 2006
  3. ncbi Palifermin decreases severe oral mucositis of patients undergoing postoperative radiochemotherapy for head and neck cancer: a randomized, placebo-controlled trial
    Michael Henke
    University Clinic Freiburg, Germany
    J Clin Oncol 29:2815-20. 2011
  4. ncbi CT-based study on potential mediastinal lymph node spread of patients with lung cancer. Contribution to 3-D treatment planning for adjuvant radiotherapy of the mediastinum
    Joachim Slanina
    Department of Radiation Therapy, Radiological University Clinic, Freiburg, Germany
    Strahlenther Onkol 178:199-208. 2002
  5. ncbi Blood hemoglobin level and treatment outcome of early breast cancer
    Michael Henke
    Department of Radiotherapy, Radiological University Clinic, University Freiburg, Germany
    Strahlenther Onkol 180:45-51. 2004
  6. ncbi Erythropoietin to treat head and neck cancer patients with anaemia undergoing radiotherapy: randomised, double-blind, placebo-controlled trial
    Michael Henke
    Abteilung Strahlenheilkunde der Radiologischen Universitätsklinik, Hugstetter Strasse 55, D 79106, Freiburg, Germany
    Lancet 362:1255-60. 2003
  7. ncbi Do erythropoietin receptors on cancer cells explain unexpected clinical findings?
    Michael Henke
    Klinik fur Strahlenheilkunde, Universitatsklinikum, Robert Koch Strasse, 3 D 79106, Freiburg, Germany
    J Clin Oncol 24:4708-13. 2006
  8. ncbi Blood hemoglobin level may affect radiosensitivity-preliminary results on acutely reacting normal tissues
    M Henke
    Abteilung Strahlentherapie, Radiologische Universitatsklinik, Freiburg, Germany
    Int J Radiat Oncol Biol Phys 48:339-45. 2000
  9. ncbi Erythropoietin in radiation oncology - A review. 1st international conference, Freiburg, June 11-12, 1999
    M Henke
    Radiotherapy Department, Radiological University Clinic, Freiburg i Br, Germany
    Oncology 58:175-82. 2000
  10. ncbi Correction of cancer anemia--impact on disease course, prognosis and treatment efficacy, particularly for patients undergoing radiotherapy
    M Henke
    Strahlenheilkunde Radiologische Universitätsklinik, Freiburg i Br
    Onkologie 24:450-4. 2001

Detail Information

Publications28

  1. ncbi Quantitative and semiquantitative evaluation of erythropoietin-induced bone marrow signal changes in lumbar spine MRI in patients with tumor anemia
    Nadir Ghanem
    Department of Diagnostic Radiology, University Hospital Freiburg, Germany
    Onkologie 30:303-8. 2007
    ....
  2. ncbi The effects of tea extracts on proinflammatory signaling
    Frank Pajonk
    Department of Radiation Oncology, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095 1714, USA
    BMC Med 4:28. 2006
    ..We investigated the underlying molecular mechanisms and compared effects of tea extracts with the effects of epigallocatechin-gallate, the proposed most-active moiety of green tea...
  3. ncbi Palifermin decreases severe oral mucositis of patients undergoing postoperative radiochemotherapy for head and neck cancer: a randomized, placebo-controlled trial
    Michael Henke
    University Clinic Freiburg, Germany
    J Clin Oncol 29:2815-20. 2011
    ..Radiochemotherapy of head and neck cancer causes severe mucositis in most patients. We investigated whether palifermin reduces this debilitating sequela...
  4. ncbi CT-based study on potential mediastinal lymph node spread of patients with lung cancer. Contribution to 3-D treatment planning for adjuvant radiotherapy of the mediastinum
    Joachim Slanina
    Department of Radiation Therapy, Radiological University Clinic, Freiburg, Germany
    Strahlenther Onkol 178:199-208. 2002
    ..To provide a schematized and graduated CT reference series of the mediastinum showing CT-detectable lymph node areas of lung cancer patients to support 3-D treatment planning and documentation for adjuvant irradiation of the mediastinum...
  5. ncbi Blood hemoglobin level and treatment outcome of early breast cancer
    Michael Henke
    Department of Radiotherapy, Radiological University Clinic, University Freiburg, Germany
    Strahlenther Onkol 180:45-51. 2004
    ..To determine whether the blood hemoglobin concentration correlates with the prognosis of patients with early breast cancer and, if so, whether this is restricted to treatment modality...
  6. ncbi Erythropoietin to treat head and neck cancer patients with anaemia undergoing radiotherapy: randomised, double-blind, placebo-controlled trial
    Michael Henke
    Abteilung Strahlenheilkunde der Radiologischen Universitätsklinik, Hugstetter Strasse 55, D 79106, Freiburg, Germany
    Lancet 362:1255-60. 2003
    ..We investigated whether anaemia correction with epoetin beta could improve outcome of curative radiotherapy among patients with head and neck cancer...
  7. ncbi Do erythropoietin receptors on cancer cells explain unexpected clinical findings?
    Michael Henke
    Klinik fur Strahlenheilkunde, Universitatsklinikum, Robert Koch Strasse, 3 D 79106, Freiburg, Germany
    J Clin Oncol 24:4708-13. 2006
    ..Recent reports suggest that cancer control may worsen if erythropoietin is administered. We investigated whether erythropoietin receptor expression on cancer cells may correlate with this unexpected finding...
  8. ncbi Blood hemoglobin level may affect radiosensitivity-preliminary results on acutely reacting normal tissues
    M Henke
    Abteilung Strahlentherapie, Radiologische Universitatsklinik, Freiburg, Germany
    Int J Radiat Oncol Biol Phys 48:339-45. 2000
    ..To evaluate the influence of blood hemoglobin concentration on the radiosensitivity of acutely reacting normal tissues...
  9. ncbi Erythropoietin in radiation oncology - A review. 1st international conference, Freiburg, June 11-12, 1999
    M Henke
    Radiotherapy Department, Radiological University Clinic, Freiburg i Br, Germany
    Oncology 58:175-82. 2000
    ..This report gives a summary reviewing the topic...
  10. ncbi Correction of cancer anemia--impact on disease course, prognosis and treatment efficacy, particularly for patients undergoing radiotherapy
    M Henke
    Strahlenheilkunde Radiologische Universitätsklinik, Freiburg i Br
    Onkologie 24:450-4. 2001
    ..Given the efficacy of rhEPO to stimulate erythropoiesis and improve quality of life of cancer patients and its potential to enhance radiation's efficacy seem to earn it a firm place at least in the radiooncologist's arsenal...
  11. ncbi [Alteration of radiation-induced hematotoxicity by amifostine (ethyol)]
    F Momm
    Abteilung Strahlentherapie, Radiologische Universitatsklinik, Freiburg
    Strahlenther Onkol 175:2-5. 1999
    ..Radiotherapy--even of small volumes--can decrease leukocyte counts. We examined whether the radio-protector amifostine can reduce this hematotoxicity...
  12. ncbi FDG-PET imaging for the staging and follow-up of small cell lung cancer
    T Schumacher
    Division of Nuclear Medicine, Albert Ludwigs University, Medical Center, Freiburg, Germany
    Eur J Nucl Med 28:483-8. 2001
    ..Finally, all findings considered suspicious for tumour involvement on the other staging procedures were also detected by FDG-PET. It is concluded that FDG-PET has potential for use as a simplified staging tool for small cell lung cancer...
  13. ncbi Alteration of radiation-induced hematotoxicity by amifostine
    F Momm
    Department of Radiotherapy, University Clinic Freiburg, Freiburg, Germany
    Int J Radiat Oncol Biol Phys 51:947-51. 2001
    ..To investigate whether amifostine can reduce radiation hematotoxicity...
  14. ncbi Impact of [18F]FDG-PET on the primary staging of small-cell lung cancer
    I Brink
    Division of Nuclear Medicine, University Hospital, Freiburg, Germany
    Eur J Nucl Med Mol Imaging 31:1614-20. 2004
    ..The purpose of this study was to evaluate the impact of [18F]fluorodeoxy-D-glucose positron emission tomography (FDG-PET) on the primary staging of patients with small-cell lung cancer (SCLC)...
  15. ncbi Epithelial cells in the peripheral blood of patients with cancer of the head and neck: incidence, detection and possible clinical significance
    F Pajonk
    Department of Radiotherapy, Radiological University Clinic, Hugstetter Strasse 55, 79106, Freiburg i. Brsg, Germany
    Radiother Oncol 59:213-7. 2001
    ..Detection of cytokeratin-19-positive cells coincided with local failure, distant metastasis and anemia...
  16. ncbi Moist skin care can diminish acute radiation-induced skin toxicity
    Felix Momm
    Department of Radiation Therapy, Radiologic University Hospital, Freiburg i Br, Germany
    Strahlenther Onkol 179:708-12. 2003
    ..There are several methods of managing them. Validity of these methods, however, is not sufficiently studied. We therefore investigated, whether moist skin care with 3% urea lotion will reduce acute radiation skin toxicity...
  17. ncbi Venous thromboembolism and mortality associated with recombinant erythropoietin and darbepoetin administration for the treatment of cancer-associated anemia
    Charles L Bennett
    VA Chicago Healthcare System, Department of Medicine, Northwestern University Feinberg School of Medicine, and Robert H Lurie Comprehensive Cancer Center, Northwestern University, Chicago, Illinois 60611, USA
    JAMA 299:914-24. 2008
    ..Although systematic overviews of trials have identified venous thromboembolism (VTE) risks, none have identified mortality risks with ESAs...
  18. ncbi Does radiation prevent 5-fluorouracil-induced colitis in the early phase of radiochemotherapy? A case report and literature review
    Hans Christian Rischke
    Department of Radiotherapy, University Hospital Freiburg, Germany
    Strahlenther Onkol 183:459-63. 2007
    ..A palliative chemotherapy with 5-FU, oxaliplatin, and leucovorin was started. Again, the patient suffered from severe diarrhea and dose reduction was necessary...
  19. ncbi Religious belief as a coping strategy: an explorative trial in patients irradiated for head-and-neck cancer
    Gerhild Becker
    Department of Internal Medicine II, University Clinic, Freiburg, Germany
    Strahlenther Onkol 182:270-6. 2006
    ..CONCLUSION: Religious faith seems to play an important role in coping strategies of radiotherapy patients. More research in this area would be worthwhile...
  20. ncbi Anemia and long-term outcome in adjuvant and neoadjuvant radiochemotherapy of stage II and III rectal adenocarcinoma: the Freiburg experience (1989-2002)
    Christian Weissenberger
    Department of Radiotherapy, University Hospital of Freiburg, 79106 Freiburg, Germany
    World J Gastroenterol 12:1849-58. 2006
    ....
  21. ncbi Influence of intravenous amifostine on xerostomia, tumor control, and survival after radiotherapy for head-and- neck cancer: 2-year follow-up of a prospective, randomized, phase III trial
    Todd H Wasserman
    Department of Radiation Oncology, Washington University, St Louis, MO 63110 1046, USA
    Int J Radiat Oncol Biol Phys 63:985-90. 2005
    ....
  22. ncbi Erythropoietin in the treatment of cancer
    Michael Henke
    Onkologie 28:181-2. 2005
  23. ncbi The erythropoietin-receptor pathway modulates survival of cancer cells
    Frank Pajonk
    Clinical and Experimental Radiation Biology Research Section, Department of Radiation Therapy, Radiological University Clinic, Robert Koch Str 3, 79106 Freiburg i Brsg, Germany
    Oncogene 23:8987-91. 2004
    ..As most human tumors express erythropoietin receptor, we advocate a restricted use erythropoietin to patients suffering from erythropoietin-receptor-expressing cancers...
  24. ncbi A multinational, randomized phase III trial of iseganan HCl oral solution for reducing the severity of oral mucositis in patients receiving radiotherapy for head-and-neck malignancy
    Andy Trotti
    Radiation Oncology Program, H Lee Moffitt Cancer Center at the University of South Florida, Tampa, FL, USA
    Int J Radiat Oncol Biol Phys 58:674-81. 2004
    ..It is hypothesized that infection plays a role in the development of OM. We tested the efficacy of iseganan HCl (iseganan), a synthetic peptide with broad-spectrum antimicrobial activity, for preventing RT-associated OM...
  25. ncbi Vitiligo at the sites of irradiation in a patient with Hodgkin's disease
    Frank Pajonk
    Department of Radiation Therapy, Radiological University Clinic, Freiburg Br, Germany
    Strahlenther Onkol 178:159-62. 2002
    ..Current hypotheses discuss autoimmune, autotoxic and neuronal mechanisms. Here we report the case of radiation-induced depigmentation of the skin of a patient with Hodgkin's disease and 25-year history of vitiligo...
  26. ncbi Metastatic breast cancer causing gas gangrene
    Felix Momm
    J Pain Symptom Manage 31:385. 2006
  27. ncbi Erythropoietin receptors on cancer cells: exciting perspectives, difficult to appreciate
    Michael Henke
    Blood 108:1107-8; author reply 1108-9. 2006
  28. ncbi Psychosocial distress and need for psychotherapeutic treatment in cancer patients undergoing radiotherapy
    Kurt Fritzsche
    Department for Psychosomatics and Psychotherapy, University Hospital Freiburg, Hauptstr. 8, D-79114 Freiburg, Germany
    Radiother Oncol 72:183-9. 2004
    ..There is a need to develop screening instruments that integrate both aspects...