Research Topics
| Claudia HeilmannSummaryAffiliation: University Hospital Country: Germany Publications
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Detail Information
Publications
Acquired Von Willebrand syndrome is an early-onset problem in ventricular assist device patientsClaudia Heilmann
Department of Cardiovascular Surgery, University Heart Center Freiburg Bad Krozingen, Hugstetter Str 55, 79194 Freiburg, Germany
Eur J Cardiothorac Surg 40:1328-33; discussion 1233. 2011..The onset of AVWS after VAD implantation is not yet determined. We examined VAD patients for presence of an AVWS in the early, intermediate, and late phase after VAD implantation...- Established markers of renal and hepatic failure are not appropriate to predict mortality in the acute stage before extracorporeal life support implantationClaudia Heilmann
Department of Cardiovascular Surgery, University Heart Center Freiburg Bad Krozingen, Freiburg, Germany
Eur J Cardiothorac Surg 42:135-41; discussion 141. 2012..Even established global scores are not always useful in the rapid decision process for ECLS. Therefore, we evaluated laboratory parameters for kidney or liver function and for inflammation and acid-base balance with regard to outcome... - Does listing for heart transplant for longer than 30 days before ventricular assist device implantation influence utilization of psychotherapeutic support and outcome?Claudia Heilmann
Department of Cardiovascular Surgery Freiburg, University Heart Center Freiburg Bad Krozingen, Freiburg, Germany
Eur J Cardiothorac Surg 41:1371-6; discussion 1376. 2012..Listing for transplant may trigger psychosocial adjustment to the transplantation as an upcoming critical life-event. We hypothesized that patients could profit from this adaptation when implantation of a VAD becomes necessary... - Supportive psychotherapy for patients with heart transplantation or ventricular assist devicesClaudia Heilmann
Department of Cardiovascular Surgery, University Heart Center Freiburg Bad Krozingen, Hugstetter Str 55, 79196 Freiburg, Germany
Eur J Cardiothorac Surg 39:e44-50. 2011..In addition, we evaluated the use for supportive psychotherapy for the families of our patients and present two typical cases... - Acquired von Willebrand syndrome in patients with extracorporeal life support (ECLS)Claudia Heilmann
Department of Cardiovascular Surgery, University Heart Center Freiburg Bad Krozingen, Hugstetter Str 55, 79106 Freiburg, Germany
Intensive Care Med 38:62-8. 2012..Since ECLS and VAD share several features, we investigated patients with ECLS for AVWS... 
Thoratec paracorporeal biventricular assist device therapy: the Freiburg experienceKerstin Brehm
Department of Cardiovascular Surgery, University Heart Center Freiburg Bad Krozingen, Freiburg, Germany
Eur J Cardiothorac Surg 41:207-12; discussion 212. 2012..The treatment of severe biventricular (BV) contractile failure using mechanical circulatory support is challenging. We analyzed our center's results following implantation of a biventricular assist device (BVAD)...- Acquired von Willebrand syndrome in patients with ventricular assist device or total artificial heartClaudia Heilmann
Department of Pediatrics and Adolescent Medicine, University Medical Center Freiburg, Mathildenstrasse 1, 79106 Freiburg, Germany
Thromb Haemost 103:962-7. 2010..In addition, TAH patients do not develop AVWS. These results suggest that shear stress associated with exposure of blood to VAD cannulas and tubes may contribute to the development of AVWS... - Scaffold-based transplantation of vascular endothelial growth factor-overexpressing stem cells leads to neovascularization in ischemic myocardium but did not show a functional regenerative effectRobert von Wattenwyl
Department of Cardiovascular Surgery, University Hospital Medical Center Freiburg, Germany
ASAIO J 58:268-74. 2012..No functional myocardial recovery was observed. Scaffold-based transfer of genetically-modified cells remains a useful tool to study paracrine stem cell action... - Haemolysis in patients with ventricular assist devices: major differences between systemsClaudia Heilmann
Department of Cardiovascular Surgery, University Medical Center Freiburg, Hugstetter Str 55, 79106 Freiburg, Germany
Eur J Cardiothorac Surg 36:580-4. 2009..This complex also undergoes lysosomal degradation in various cells. Only now, the excessive free haemoglobin can be measured in plasma. Here, we investigated haemolysis in patients supported by different VAD types... - Non-surgical bleeding in patients with ventricular assist devices could be explained by acquired von Willebrand diseaseUlrich Geisen
Department of Clinical Chemistry, University Medical Center Freiburg, Freiburg, Germany
Eur J Cardiothorac Surg 33:679-84. 2008..We, therefore, analysed patients with two VAD types for laboratory parameters of VWD and compared them with patients after heart transplantation (HTX)... - Scaffold-based transplantation of akt1-overexpressing skeletal myoblasts: functional regeneration is associated with angiogenesis and reduced infarction sizeMatthias Siepe
Department of Cardiovascular Surgery, University Medical Center Freiburg, Freiburg, Germany
Tissue Eng Part A 17:205-12. 2011..In conclusion, SkM overexpressing Akt1 can maintain myocardial function after infarction, reduce infarction size, and induce neovascularization. Scaffold-based cell transfer does not augment this reverse remodeling capacity... - Polyurethane scaffolds seeded with genetically engineered skeletal myoblasts: a promising tool to regenerate myocardial functionBritta Blumenthal
Department of Cardiovascular Surgery, University Medical Center Freiburg, Freiburg, Germany
Artif Organs 34:E46-54. 2010..Because this matrix also allows us to circumvent previous cell application drawbacks, it may represent a promising tool for tissue regeneration and the re-establishment of cardiac function after myocardial infarction... - Determination of vessel wall dynamics by optical microsensorsDominic Ruh
Department of Microsystems Engineering, University of Freiburg, Freiburg, Germany
Conf Proc IEEE Eng Med Biol Soc 2012:2359-62. 2012..Intra-arterial blood pressure also shows a linear interrelationship with the optical signal. Measurements of blood vessel wall dynamics has great potential to quantify arteriosclerosis by this new and innovative approach... - Successful resuscitation after prolonged periods of cardiac arrest: a new field in cardiac surgeryGeorg Trummer
School of Medicine, Albert Ludwigs University Freiburg, Freiburg, Germany
J Thorac Cardiovasc Surg 139:1325-32, 1332.e1-2. 2010..We assessed the hypothesis that controlled reperfusion of the whole body with cardiopulmonary bypass would limit reperfusion injury after 15 minutes of normothermic cardiac arrest with better survival and neurological recovery... - An implantable optical blood pressure sensor based on pulse transit timeJens Fiala
Department of Microsystems Engineering IMTEK, Laboratory for Micro optics, University of Freiburg, Georges Koehler Allee 102, Freiburg, 79110, Germany
Biomed Microdevices 15:73-81. 2013..In addition, spectrophotometric approaches allow measurement of hemoglobin derivatives. For the calibration of blood pressure measurements, the sensor system has been successfully implemented in animal models... - Wound complications after median sternotomy: a single-centre studyClaudia Heilmann
Department of Cardiovascular Surgery, Heart Center Freiburg University, Freiburg, Germany
Interact Cardiovasc Thorac Surg 16:643-8. 2013..Redo and emergency operations are the most important risk factors in this contemporary series. More efforts seem mandatory to decrease this arduous morbidity and the costs of prolonged treatment... 
Improvement of contractility accompanies angiogenesis rather than arteriogenesis in chronic myocardial ischemiaClaudia Heilmann
Department of Cardiovascular Surgery, University Hospital Freiburg, Hugstetter Str 55, 79106 Freiburg, Germany
Vascul Pharmacol 44:326-32. 2006..We hypothesised a synergetic effect of FGF-2 and MCP-1 in ischemic myocardium...- Stem cell research and cell transplantation for myocardial regenerationMatthias Siepe
Department of Cardiovascular Surgery, University Clinic, Albert Ludwigs University Freiburg, Hugstetterstrasse 55, 79106 Freiburg, Germany
Eur J Cardiothorac Surg 28:318-24. 2005..This overview will focus on objectives, recent achievements, and future perspectives of diverse stem cell transplantation approaches... - Lymph angiogenesis after lung transplantation and relation to acute organ rejection in humansAlexey Dashkevich
Department of Cardiovascular Surgery, Freiburg University Medical Centre, Freiburg, Germany
Ann Thorac Surg 90:406-11. 2010..However, the relation of lymph angiogenesis to acute rejection in lung transplantation has not yet been investigated...