Iris M Heid

Summary

Affiliation: University of Regensburg
Country: Germany

Publications

  1. pmc Meta-analysis of the INSIG2 association with obesity including 74,345 individuals: does heterogeneity of estimates relate to study design?
    Iris M Heid
    Helmholtz Zentrum Munchen, German Research Center for Environmental Health, Neuherberg, Germany
    PLoS Genet 5:e1000694. 2009
  2. pmc Joint analysis of individual participants' data from 17 studies on the association of the IL6 variant -174G>C with circulating glucose levels, interleukin-6 levels, and body mass index
    Cornelia Huth
    Institute of Epidemiology, Helmholtz Zentrum Munchen, Neuherberg, Germany
    Ann Med 41:128-38. 2009
  3. doi request reprint Haplotype misclassification resulting from statistical reconstruction and genotype error, and its impact on association estimates
    Claudia Lamina
    Institute of Epidemiology, Helmholtz Zentrum Munchen German Research Center for Environmental Health, Neuherberg, Germany
    Ann Hum Genet 74:452-62. 2010
  4. doi request reprint Association of the MC4R V103I polymorphism with the metabolic syndrome: the KORA Study
    Iris M Heid
    Institute of Epidemiology, GSF National Research Center for Environment and Health, Neuherberg, Germany
    Obesity (Silver Spring) 16:369-76. 2008
  5. doi request reprint Genome-wide association analysis of high-density lipoprotein cholesterol in the population-based KORA study sheds new light on intergenic regions
    Iris M Heid
    Institute of Epidemiology, Helmholtz Center, Munich, German Research Center for Environmental Health, Neuherberg, Germany
    Circ Cardiovasc Genet 1:10-20. 2008
  6. ncbi request reprint Fibrinogen genes modify the fibrinogen response to ambient particulate matter
    Annette Peters
    Helmholtz Zentrum Munchen, German Research Center for Environmental Health, Institute of Epidemiology, Ingolstaedter Landstrasse, Neuherberg 85764, Germany
    Am J Respir Crit Care Med 179:484-91. 2009
  7. pmc Haplotype reconstruction error as a classical misclassification problem: introducing sensitivity and specificity as error measures
    Claudia Lamina
    Institute of Epidemiology, Helmholtz Zentrum Munchen German Research Center for Environmental Health, Neuherberg, Germany
    PLoS ONE 3:e1853. 2008
  8. ncbi request reprint APOA5 variants and metabolic syndrome in Caucasians
    Harald Grallert
    Institute of Epidemiology, GSF National Research Center for Environment and Health, Neuherberg, Germany
    J Lipid Res 48:2614-21. 2007
  9. ncbi request reprint IL6 gene promoter polymorphisms and type 2 diabetes: joint analysis of individual participants' data from 21 studies
    Cornelia Huth
    GSF Institute of Epidemiology, Neuherberg, Germany
    Diabetes 55:2915-21. 2006

Detail Information

Publications9

  1. pmc Meta-analysis of the INSIG2 association with obesity including 74,345 individuals: does heterogeneity of estimates relate to study design?
    Iris M Heid
    Helmholtz Zentrum Munchen, German Research Center for Environmental Health, Neuherberg, Germany
    PLoS Genet 5:e1000694. 2009
    ..The importance of study design might be under-recognized in gene discovery and association replication so far...
  2. pmc Joint analysis of individual participants' data from 17 studies on the association of the IL6 variant -174G>C with circulating glucose levels, interleukin-6 levels, and body mass index
    Cornelia Huth
    Institute of Epidemiology, Helmholtz Zentrum Munchen, Neuherberg, Germany
    Ann Med 41:128-38. 2009
    ..Several studies have investigated associations between the -174G>C single nucleotide polymorphism (rs1800795) of the IL6 gene and phenotypes related to type 2 diabetes mellitus (T2DM) but presented inconsistent results...
  3. doi request reprint Haplotype misclassification resulting from statistical reconstruction and genotype error, and its impact on association estimates
    Claudia Lamina
    Institute of Epidemiology, Helmholtz Zentrum Munchen German Research Center for Environmental Health, Neuherberg, Germany
    Ann Hum Genet 74:452-62. 2010
    ..Our findings give a sense of the impact of haplotype error under realistic scenarios and underscore the importance of high-quality genotyping, in which case the bias in haplotype association estimates is negligible...
  4. doi request reprint Association of the MC4R V103I polymorphism with the metabolic syndrome: the KORA Study
    Iris M Heid
    Institute of Epidemiology, GSF National Research Center for Environment and Health, Neuherberg, Germany
    Obesity (Silver Spring) 16:369-76. 2008
    ..This study aims to provide epidemiological evidence for showing the association of this polymorphism with features of the metabolic syndrome and with parameters related to energy expenditure and dietary habits as potential mediators...
  5. doi request reprint Genome-wide association analysis of high-density lipoprotein cholesterol in the population-based KORA study sheds new light on intergenic regions
    Iris M Heid
    Institute of Epidemiology, Helmholtz Center, Munich, German Research Center for Environmental Health, Neuherberg, Germany
    Circ Cardiovasc Genet 1:10-20. 2008
    ..We aimed to identify gene regions that influence HDLC levels by a genome-wide association analysis in the population-based KORA (Cooperative Health Research in the Region of Augsburg) study...
  6. ncbi request reprint Fibrinogen genes modify the fibrinogen response to ambient particulate matter
    Annette Peters
    Helmholtz Zentrum Munchen, German Research Center for Environmental Health, Institute of Epidemiology, Ingolstaedter Landstrasse, Neuherberg 85764, Germany
    Am J Respir Crit Care Med 179:484-91. 2009
    ..Ambient particulate matter has been associated with systemic inflammation indicated by blood markers such as fibrinogen, implicated in promoting atherothrombosis...
  7. pmc Haplotype reconstruction error as a classical misclassification problem: introducing sensitivity and specificity as error measures
    Claudia Lamina
    Institute of Epidemiology, Helmholtz Zentrum Munchen German Research Center for Environmental Health, Neuherberg, Germany
    PLoS ONE 3:e1853. 2008
    ..It was our aim to quantify haplotype reconstruction error and to provide tools for it...
  8. ncbi request reprint APOA5 variants and metabolic syndrome in Caucasians
    Harald Grallert
    Institute of Epidemiology, GSF National Research Center for Environment and Health, Neuherberg, Germany
    J Lipid Res 48:2614-21. 2007
    ..Furthermore, the data suggest a different mechanism of APOA5 impact on MetS in Caucasians, as variant c.56C>G (not analyzed in the Japanese study) and not -1131T>C, as in the Japanese subjects, was associated with MetS...
  9. ncbi request reprint IL6 gene promoter polymorphisms and type 2 diabetes: joint analysis of individual participants' data from 21 studies
    Cornelia Huth
    GSF Institute of Epidemiology, Neuherberg, Germany
    Diabetes 55:2915-21. 2006
    ....