Research Topics
| Joerg HasfordSummaryAffiliation: University of Munich Country: Germany Publications
| Collaborators
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Detail Information
Publications
Blood pressure reduction, persistence and costs in the evaluation of antihypertensive drug treatment--a reviewPeter Bramlage
Institute for Cardiovascular Pharmacology and Epidemiology, Mahlow, Germany
Cardiovasc Diabetol 8:18. 2009..This review explores the blood pressure reduction and persistence with treatment of antihypertensive drugs and the cost consequences of poor persistence with pharmaceutical interventions in arterial hypertension...
A new prognostic score for survival of patients with chronic myeloid leukemia treated with interferon alfa. Writing Committee for the Collaborative CML Prognostic Factors Project GroupJ Hasford
Institute for Medical Informatics, Biometry, and Epidemiology, University of Munich, Germany
J Natl Cancer Inst 90:850-8. 1998..A meta-analysis was conducted to develop a reliable prognostic scoring system for estimation of survival of patients with CML treated with interferon alfa...
Predicting complete cytogenetic response and subsequent progression-free survival in 2060 patients with CML on imatinib treatment: the EUTOS scoreJoerg Hasford
Institut für Medizinische Informationsverarbeitung, Biometrie und Epidemiologie, Ludwig Maximilians Universitat, Munchen, Germany
Blood 118:686-92. 2011..The score can be used to identify CML patients with significantly lower probabilities of responding to therapy and survival, thus alerting physicians to those patients who require closer observation and early intervention...
Inconsistent trial assessments by the National Institute for Health and Clinical Excellence and IQWiG: standards for the performance and interpretation of subgroup analyses are neededJ Hasford
Institut für Medizinische Informationsverarbeitung, Biometrie und Epidemiologie, LMU Munchen, Marchioninistrasse 15, Munich, Germany
J Clin Epidemiol 63:1298-304. 2010..The methodology for the critical assessment of medical interventions is well established. Regulatory agencies and institutions adhere, in principle, to the same standards. This consistency, however, is not always the case in practice...
Persistence with antihypertensive treatments: results of a 3-year follow-up cohort studyJoerg Hasford
IBE Department of Medical Informatics, Biometry and Epidemiology, Ludwig Maximilians Universitat Munchen, Marchioninistr 15, 81377, Munich, Germany
Eur J Clin Pharmacol 63:1055-61. 2007..The study described herein - which is completely independent of pharmaceutical sponsors - was undertaken to evaluate persistence with antihypertensive treatment in Germany...
The impact of the combination of baseline risk group and cytogenetic response on the survival of patients with chronic myeloid leukemia treated with interferon alphaJoerg Hasford
Universite Victor Segalen, Bordeaux, France University Hospital Groningen, Groningen, The Netherlands
Haematologica 90:335-40. 2005..MCR was defined as a reduction of Philadelphia chromosome-positive bone marrow cells to <or= 35%. The New CML score discriminated three risk groups with significantly different survival probabilities...
A naturalistic cohort study on effectiveness, safety and usage pattern of an over-the-counter nicotine patch. Cohort study on smoking cessationJoerg Hasford
Department of Medical Informatics, Biometry and Epidemiology, University of Munich, Marchioninistr 15, D 81377 Munchen, Germany
Eur J Clin Pharmacol 59:443-7. 2003..Pharmacy-based cohort studies are feasible. This study indicates that the nicotine patch is effective and safe in an OTC setting. There is still room to improve compliance with the directions for use...
Safety and usage pattern of low-dose diclofenac when used as an over-the-counter medication: results of an observational cohort study in a community-based pharmacy settingJ Hasford
Department of Medical Informatics, Biometry and Epidemiology, University of Munich, Germany
Int J Clin Pharmacol Ther 42:415-22. 2004..This study was designed to evaluate the "real life" behavior of consumers with nonprescription access to low-dose diclofenac-K, with special focus on tolerability and the pattern of product usage...
A population-based European cohort study of persistence in newly diagnosed hypertensive patientsJ Hasford
Department for Medical Informatics, Biometry and Epidemiology, University of Munich, Munich, Germany
J Hum Hypertens 16:569-75. 2002..Prescribing an antihypertensive agent that provides a favourable efficacy and tolerability profile may provide greater persistence with therapy and hence a higher level of blood pressure control...
Immunochemotherapy with rituximab and cyclophosphamide, doxorubicin, vincristine, and prednisone significantly improves response and time to treatment failure, but not long-term outcome in patients with previously untreated mantle cell lymphoma: results oGeorg Lenz
Department of Internal Medicine III of the Ludwig-Maximilians University, Marchioninistrasse 15, 81377 Munich, Germany
J Clin Oncol 23:1984-92. 2005..Hence, R-CHOP may serve as a new baseline regimen for advanced stage MCL, but needs to be further improved by novel strategies in remission...
Moderate increase of secondary hematologic malignancies after myeloablative radiochemotherapy and autologous stem-cell transplantation in patients with indolent lymphoma: results of a prospective randomized trial of the German Low Grade Lymphoma Study GroGeorg Lenz
Department of Internal Medicine III, Ludwig Maximilians University, University Hospital Grosshadern, Marchioninistrasse 15, 81377 Munich, Germany
J Clin Oncol 22:4926-33. 2004....
The Follicular Lymphoma International Prognostic Index (FLIPI) separates high-risk from intermediate- or low-risk patients with advanced-stage follicular lymphoma treated front-line with rituximab and the combination of cyclophosphamide, doxorubicin, vincChristian Buske
Department of Internal Medicine III, University of Munich, Grosshadern, Marchioninistr 15, 81377 Munchen, Germany
Blood 108:1504-8. 2006..001). Our data demonstrate that the FLIPI is able to identify high-risk patients with advanced-stage FL after first-line treatment with rituximab/chemotherapy...
A new prognostic index (MIPI) for patients with advanced-stage mantle cell lymphomaEva Hoster
Department of Internal Medicine III, University of Munich, Germany
Blood 111:558-65. 2008..The MIPI is the first prognostic index particularly suited for MCL patients and may serve as an important tool to facilitate risk-adapted treatment decisions in patients with advanced stage MCL...
The association of psychosocial factors with nausea and vomiting during pregnancyGertraud E Markl
Institute for Medical Informatics, Biometry and Epidemiology, University of Munich, Germany
J Psychosom Obstet Gynaecol 29:17-22. 2008..The purpose of this study was to identify predictors for nausea and vomiting during pregnancy (NVP)...
Drug-induced blood consumption: the impact of adverse drug reactions on demand for blood components in German departments of internal medicineDominik Rottenkolber
Ludwig Maximilians Universitat Munchen, Institute of Health Economics and Health Care Management and Munich Center of Health Sciences, Munich, Germany
Basic Clin Pharmacol Toxicol 111:240-7. 2012..Both blood demand and hospital procurement costs can be significantly lowered by preventing ADRs...
Prediction of post-remission survival in acute myeloid leukaemia: a post-hoc analysis of the AML96 trialMarkus Pfirrmann
Institut für Medizinische Informationsverarbeitung, Biometrie und Epidemiologie IBE, Ludwig Maximilians Universitat, Munich, Germany
Lancet Oncol 13:207-14. 2012..In a post-hoc analysis of the AML96 trial (NCT00180115), our aim was to differentiate groups of patients according to the treatments that would provide them optimum benefit...
Drug-related admissions and hospital-acquired adverse drug events in Germany: a longitudinal analysis from 2003 to 2007 of ICD-10-coded routine dataJurgen Stausberg
Institut für Medizinische Informationsverarbeitung, Biometrie und Epidemiologie, Ludwig Maximilians Universitat Munchen, Marchioninistrase 15, D 81377 Munchen, Germany
BMC Health Serv Res 11:134. 2011..In this study, the frequency and type of drug-related admissions and hospital-acquired adverse drug events (ADE) in Germany were assessed using routinely collected hospital data...
Adverse drug reactions in Germany: direct costs of internal medicine hospitalizationsDominik Rottenkolber
Ludwig Maximilians Universitat Munchen, Institute of Health Economics and Health Care Management and Munich Center of Health Sciences, Munich, Germany
Pharmacoepidemiol Drug Saf 20:626-34. 2011..The objective was to quantify the ADR-related economic burden (direct costs) of hospitalizations in internal medicine wards in Germany...
Costs of adverse drug events in German hospitals--a microcosting studyDominik Rottenkolber
Institute of Health Economics and Health Care Management and Munich Center of Health Sciences, LMU, Munich, Germany
Value Health 15:868-75. 2012....
Drug prescription in pregnancy: analysis of a large statutory sickness fund populationVeronika Egen-Lappe
Institute for Medical Informatics, Biometry and Epidemiology IBE, University of Munich, Marchioninistrasse 15, 81377, Munich, Germany
Eur J Clin Pharmacol 60:659-66. 2004..To examine the prescription of drugs in Germany prior to, during and after pregnancy...
Identification of adverse drug events: the use of ICD-10 coded diagnoses in routine hospital dataJurgen Stausberg
Institut für Medizinische Informationsverarbeitung, Biometrie und Epidemiologie der LMU, Muchen, Germany
Dtsch Arztebl Int 107:23-9. 2010..The aim of this study is to examine the potential usefulness of ICD-10 coded diagnoses in routine hospital data for the identification of ADE...
Prescribing patterns of anti-emetic drugs during pregnancy in GermanyGertraud E Markl
Institute for Medical Informatics, Biometry and Epidemiology IBE, University of Munich, Marchioninistrasse 15, Munich 81377, Germany
Arch Gynecol Obstet 275:461-7. 2007..The purpose of this study was to examine the prescribing patterns of anti-emetics for pregnant women in Germany...
Antibiotics in pregnancy: analysis of potential risks and determinants in a large German statutory sickness fund populationUte Amann
Institute for Medical Informatics, Biometry and Epidemiology, University of Munich, Munich, Germany
Pharmacoepidemiol Drug Saf 15:327-37. 2006..Antibiotics are frequently prescribed drugs in pregnancy. The purpose of the study was to analyse the use, the potential risks and the determinants of systemic antibiotic prescriptions during pregnancy...
Early consolidation by myeloablative radiochemotherapy followed by autologous stem cell transplantation in first remission significantly prolongs progression-free survival in mantle-cell lymphoma: results of a prospective randomized trial of the European Martin Dreyling
Department of Internal Medicine III, Ludwig-Maximilians University, Marchioninistrasse 15, 81377 Munich, Germany
Blood 105:2677-84. 2005..18). Early consolidation by myeloablative radiochemotherapy followed by ASCT is feasible and results in a significant prolongation of PFS in advanced-stage MCL. Longer follow-up is needed to determine the effect on OS...
Impact of different post-remission strategies on quality of life in patients with acute myeloid leukemiaDorle Messerer
Institut für Med Informationsverarbeitung, Biometrie und Epidemiologie der Universität München IBE, Marchioninistr 15, D 81377 Munchen, Germany
Haematologica 93:826-33. 2008..The German AML-Intergroup, therefore, initiated a survey on quality of life of patients with a relapse-free survival of at least 5 years after first-line treatment...
