Otto Haller

Summary

Affiliation: University Hospital
Country: Germany

Publications

  1. request reprint
    Haller O, Staeheli P, Kochs G. Interferon-induced Mx proteins in antiviral host defense. Biochimie. 2007;89:812-8 pubmed
    ..As a consequence, these viral components are trapped and sorted to locations where they become unavailable for the generation of new virus particles. ..
  2. Haller O, Gao S, von der Malsburg A, Daumke O, Kochs G. Dynamin-like MxA GTPase: structural insights into oligomerization and implications for antiviral activity. J Biol Chem. 2010;285:28419-24 pubmed publisher
    ..Moreover, the structural knowledge paves the way for the development of novel antiviral drugs against influenza and other highly pathogenic viruses. ..
  3. Haller O, Kochs G. Human MxA protein: an interferon-induced dynamin-like GTPase with broad antiviral activity. J Interferon Cytokine Res. 2011;31:79-87 pubmed publisher
    ..Thus, MxA may form oligomeric rings around tubular nucleocapsid structures, thereby inhibiting their transcriptional and replicative function. Here we briefly review the most salient features of MxA expression and antiviral function. ..
  4. Haller O. Dynamins are forever: MxB inhibits HIV-1. Cell Host Microbe. 2013;14:371-3 pubmed publisher
    ..Three recent papers, including one in this issue of Cell Host & Microbe, show that MxB inhibits human immunodeficiency virus type 1 (HIV-1) infection. ..

Locale

Detail Information

Publications4

  1. request reprint
    Haller O, Staeheli P, Kochs G. Interferon-induced Mx proteins in antiviral host defense. Biochimie. 2007;89:812-8 pubmed
    ..As a consequence, these viral components are trapped and sorted to locations where they become unavailable for the generation of new virus particles. ..
  2. Haller O, Gao S, von der Malsburg A, Daumke O, Kochs G. Dynamin-like MxA GTPase: structural insights into oligomerization and implications for antiviral activity. J Biol Chem. 2010;285:28419-24 pubmed publisher
    ..Moreover, the structural knowledge paves the way for the development of novel antiviral drugs against influenza and other highly pathogenic viruses. ..
  3. Haller O, Kochs G. Human MxA protein: an interferon-induced dynamin-like GTPase with broad antiviral activity. J Interferon Cytokine Res. 2011;31:79-87 pubmed publisher
    ..Thus, MxA may form oligomeric rings around tubular nucleocapsid structures, thereby inhibiting their transcriptional and replicative function. Here we briefly review the most salient features of MxA expression and antiviral function. ..
  4. Haller O. Dynamins are forever: MxB inhibits HIV-1. Cell Host Microbe. 2013;14:371-3 pubmed publisher
    ..Three recent papers, including one in this issue of Cell Host & Microbe, show that MxB inhibits human immunodeficiency virus type 1 (HIV-1) infection. ..