Marce E Halatsch

Summary

Affiliation: University of Heidelberg
Country: Germany

Publications

  1. ncbi Combination treatment of glioblastoma multiforme cell lines with the anti-malarial artesunate and the epidermal growth factor receptor tyrosine kinase inhibitor OSI-774
    Thomas Efferth
    Center for Molecular Biology, University of Heidelberg, Im Neuenheimer Feld 282, Heidelberg 69120, Germany
    Biochem Pharmacol 67:1689-700. 2004
  2. ncbi Epidermal growth factor receptor inhibition for the treatment of glioblastoma multiforme and other malignant brain tumours
    Marc Eric Halatsch
    Department of Neurosurgery, University of Heidelberg, Im Neuenheimer Feld 400, D 69120 Heidelberg, Germany
    Cancer Treat Rev 32:74-89. 2006
  3. ncbi Uniform MDM2 overexpression in a panel of glioblastoma multiforme cell lines with divergent EGFR and p53 expression status
    Marc E Halatsch
    Department of Neurosurgery, Ruprecht Karls University, Im Neuenheimer Feld 400, D 69120 Heidelberg, Germany
    Anticancer Res 26:4191-4. 2006
  4. ncbi Epidermal growth factor receptor pathway gene expressions and biological response of glioblastoma multiforme cell lines to erlotinib
    Marce E Halatsch
    Department of Neurosurgery, Ruprecht Karls University, Im Neuenheimer Feld 400, D 69120 Heidelberg, Germany
    Anticancer Res 28:3725-8. 2008
  5. ncbi Inverse correlation of epidermal growth factor receptor messenger RNA induction and suppression of anchorage-independent growth by OSI-774, an epidermal growth factor receptor tyrosine kinase inhibitor, in glioblastoma multiforme cell lines
    Marc Eric Halatsch
    Klinik und Poliklinik fur Neurochirurgie, Georg August Universitat, Gottingen, Germany
    J Neurosurg 100:523-33. 2004
  6. ncbi Specific patterns of DNA copy number gains and losses in eight new glioblastoma multiforme cell lines
    Tzutzuy Ramirez
    Institute of Human Genetics, University of Erlangen Nuremberg, D 91054 Erlangen, Germany
    Int J Oncol 23:453-60. 2003

Collaborators

  • Thomas Efferth
  • Tzutzuy Ramirez
  • Erich Gebhart
  • Lucia Taja-Chayeb
  • Luis A Herrera
  • Karen Thoma

Detail Information

Publications6

  1. ncbi Combination treatment of glioblastoma multiforme cell lines with the anti-malarial artesunate and the epidermal growth factor receptor tyrosine kinase inhibitor OSI-774
    Thomas Efferth
    Center for Molecular Biology, University of Heidelberg, Im Neuenheimer Feld 282, Heidelberg 69120, Germany
    Biochem Pharmacol 67:1689-700. 2004
    ..In conclusion, the combination treatment of ART and OSI-774 resulted in an increased growth inhibition of GBM cell lines as compared to each drug alone...
  2. ncbi Epidermal growth factor receptor inhibition for the treatment of glioblastoma multiforme and other malignant brain tumours
    Marc Eric Halatsch
    Department of Neurosurgery, University of Heidelberg, Im Neuenheimer Feld 400, D 69120 Heidelberg, Germany
    Cancer Treat Rev 32:74-89. 2006
    ..Further studies will define their clinical potential and hopefully provide new, effective treatments for GBM and other malignant brain tumours...
  3. ncbi Uniform MDM2 overexpression in a panel of glioblastoma multiforme cell lines with divergent EGFR and p53 expression status
    Marc E Halatsch
    Department of Neurosurgery, Ruprecht Karls University, Im Neuenheimer Feld 400, D 69120 Heidelberg, Germany
    Anticancer Res 26:4191-4. 2006
    ..Overexpression and deletion mutation of the epidermal growth factor receptor (EGFR) gene, as well as murine double minute 2 (MDM2) overexpression have been linked to the absence of p53 gene mutations in human glioblastoma multiforme (GBM)...
  4. ncbi Epidermal growth factor receptor pathway gene expressions and biological response of glioblastoma multiforme cell lines to erlotinib
    Marce E Halatsch
    Department of Neurosurgery, Ruprecht Karls University, Im Neuenheimer Feld 400, D 69120 Heidelberg, Germany
    Anticancer Res 28:3725-8. 2008
    ..The aim of the current study was to determine which genes within the EGFR signaling pathway are candidates for mediating the cellular response of human GBM towards erlotinib...
  5. ncbi Inverse correlation of epidermal growth factor receptor messenger RNA induction and suppression of anchorage-independent growth by OSI-774, an epidermal growth factor receptor tyrosine kinase inhibitor, in glioblastoma multiforme cell lines
    Marc Eric Halatsch
    Klinik und Poliklinik fur Neurochirurgie, Georg August Universitat, Gottingen, Germany
    J Neurosurg 100:523-33. 2004
    ..The aim of the current study was to evaluate molecular and cellular effects of OSI-774, a novel EGFR tyrosine kinase inhibitor, on nine glioblastoma multiforme (GBM) cell lines...
  6. ncbi Specific patterns of DNA copy number gains and losses in eight new glioblastoma multiforme cell lines
    Tzutzuy Ramirez
    Institute of Human Genetics, University of Erlangen Nuremberg, D 91054 Erlangen, Germany
    Int J Oncol 23:453-60. 2003
    ..Eventually, each of the cell lines could be characterized by its specific pattern of genomic imbalance...