Research Topics
| G HajakSummaryAffiliation: University of Regensburg Country: Germany Publications
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Detail Information
Publications
Abuse and dependence potential for the non-benzodiazepine hypnotics zolpidem and zopiclone: a review of case reports and epidemiological dataG Hajak
Department of Psychiatry and Psychotherapy, University of Regensburg, Germany
Addiction 98:1371-8. 2003..To substantiate and re-evaluate this situation, the world literature was reviewed for cases of dependence of both agents; these cases were analysed in order to identify certain underlying patterns, if evident...
Continuous versus non-nightly use of zolpidem in chronic insomnia: results of a large-scale, double-blind, randomized, outpatient studyG Hajak
Department of Psychiatry and Psychotherapy, University of Regensburg, Germany
Int Clin Psychopharmacol 17:9-17. 2002..Non-nightly zolpidem appears to be a feasible and safe additional option for the management of chronic insomnia...
The challenge of chronic insomnia: is non-nightly hypnotic treatment a feasible alternative?G Hajak
Department of Psychiatry and Psychotherapy, University of Regensburg, Universitatsstrasse 84, 93053 Regensburg, Germany
Eur Psychiatry 18:201-8. 2003..Published results show effective treatment of insomnia without any evidence of either adverse event associated with a discontinuous regimen or increased hypnotic use over the treatment period...
"As needed" pharmacotherapy combined with stimulus control treatment in chronic insomnia--assessment of a novel intervention strategy in a primary care settingGoran Hajak
Department of Psychiatry and Psychotherapy, University of Regensburg, Germany
Ann Clin Psychiatry 14:1-7. 2002..Further research is warranted on the contributions of both treatment components to effectiveness and on the efficacy and safety issues of long-term use...
Zolpidem "as needed" versus continuous administration: Pan-European study resultsGoran Hajak
Department of Psychiatry and Psychotherapy, University of Regensburg, Germany
Sleep Med Rev 6:S21-8; discussion S31-3. 2002
Doxepin in the treatment of primary insomnia: a placebo-controlled, double-blind, polysomnographic studyG Hajak
Department of Psychiatry and Psychotherapy, , Germany
J Clin Psychiatry 62:453-63. 2001....
rTMS for the treatment of tinnitus: the role of neuronavigation for coil positioningB Langguth
Department of Psychiatry and Psychotherapy, University of Regensburg, Universitaetsstrasse 84, 93053 Regensburg, Germany
Neurophysiol Clin 40:45-58. 2010....
The sleep-improving effects of doxepin are paralleled by a normalized plasma cortisol secretion in primary insomnia. A placebo-controlled, double-blind, randomized, cross-over study followed by an open treatment over 3 weeksA Rodenbeck
Department of Psychiatry and Psychotherapy, University of Gottingen, Von Siebold Strasse 5, 37075 Gottingen, Germany
Psychopharmacology (Berl) 170:423-8. 2003....
Left temporal low-frequency rTMS for the treatment of tinnitus: clinical predictors of treatment outcome--a retrospective studyG Frank
Department of Psychiatry and Psychotherapy, University of Regensburg, Regensburg, Germany
Eur J Neurol 17:951-6. 2010..However, treatment results are characterized by high interindividual variability. Therefore, the identification of predictors for treatment response is of high clinical relevance...
Cognitive and neurobiological alterations in electromagnetic hypersensitive patients: results of a case-control studyM Landgrebe
Department of Psychiatry, Psychosomatics, and Psychotherapy, University of Regensburg, Regensburg, Germany
Psychol Med 38:1781-91. 2008....
Modulating cerebello-thalamocortical pathways by neuronavigated cerebellar repetitive transcranial stimulation (rTMS)B Langguth
Department of Psychiatry, Psychosomatics and Psychotherapy, University of Regensburg, Universitaetsstrasse, 84, 93053 Regensburg, Germany
Neurophysiol Clin 38:289-95. 2008..This study explores the effects of cerebellar repetitive transcranial magnetic stimulation (rTMS) on cerebello-thalamocortical pathways...
TMS for treatment of chronic tinnitus: neurobiological effectsP Eichhammer
Department of Psychiatry, University of Regensburg, Universitaetsstrasse 84, 93053, Regensburg, Germany
Prog Brain Res 166:369-75. 2007..All other signs of cortical excitability that we studied remained unchanged. These findings suggest, that low frequency rTMS may evoke long-term depression (LTD)-like effects resulting in enhancement of subcortical inhibition...
Neuroendocrine dysregulation in primary insomniaA Rodenbeck
Department of Psychiatry and Psychotherapy, Georg August University of Gottingen, Von Siebold Str 5, 37075 Gottingen, Germany
Rev Neurol (Paris) 157:S57-61. 2001..Taken together, the neuroendocrine dysregulation seems to be more expressed in chronic insomnia than in acute insomnia and may be a contributing factor in maintaining disturbed sleep...
Decreased sleep quality and increased sleep related movements in patients with Tourette's syndromeS Cohrs
Department of Psychiatry and Psychotherapy, von Sieboldstrasse 5, 37075 Goettingen, Germany
J Neurol Neurosurg Psychiatry 70:192-7. 2001....
Epidemiology of severe insomnia and its consequences in GermanyG Hajak
Department of Psychiatry and Psychotherapy, University of Regensburg, Germany
Eur Arch Psychiatry Clin Neurosci 251:49-56. 2001....
Tinnitus severity, depression, and the big five personality traitsB Langguth
Department of Psychiatry, University of Regensburg, Regensburg, Germany
Prog Brain Res 166:221-5. 2007..001) and TQ scores (p=.028), but not with THI ratings (n.s.). In addition to confirming the established roles of trait anxiety and depression, low 'Agreeableness' was thus identified as a novel predictor of tinnitus severity on the THI...
Effects of acupuncture needle penetration on motor system excitabilityM Zunhammer
Department of Psychiatry, University of Regensburg, Universitaetsstrae 84, 93053 Regensburg, Germany
Neurophysiol Clin 42:225-30. 2012..The present study aimed at exploring effects of deep manual acupuncture needling compared to a state-of-the-art, non-penetrating control condition on several standard TMS measures of motor system excitability...
Functional imaging of chronic tinnitus: the use of positron emission tomographyP Eichhammer
Department of Psychiatry, University of Regensburg, Universitaetsstrasse 84, 93053, Regensburg, Germany
Prog Brain Res 166:83-8. 2007..PET studies that map distinct neurochemical pathways and receptors by the use of specific ligands may in the future provide new possibilities for pharmacologically based treatment of some forms of tinnitus...
Suprathreshold repetitive transcranial magnetic stimulation elevates thyroid-stimulating hormone in healthy male subjectsS Cohrs
Department of Psychiatry and Psychotherapy, Georg-August University, , Germany
J Nerv Ment Dis 189:393-7. 2001..The more pronounced effect of suprathreshold rTMS on TSH plasma levels might be important for the determination of optimal stimulation parameters in the treatment of depressed patients...
Separation anxiety and actual separation experiences during childhood in patients with panic disorderB Bandelow
Department of Psychiatry and Psychotherapy, University of Gottingen, Germany
Can J Psychiatry 46:948-52. 2001..The association between separation anxiety in childhood and actual separation experiences during childhood has not yet been investigated in patients with panic disorder...
Positron emission tomography findings in obstructive sleep apnea patients with residual sleepiness treated with continuous positive airway pressureJ Antczak
Sleep Disorders and Research Centre, Department of Psychiatry and Psychotherapy, University of Regensburg, Regensburg, Germany
J Physiol Pharmacol 58:25-35. 2007..Abnormal PET findings were concentrated in frontal area (found in 4 patients). The frontal abnormality seems to distinguish the OSAS patients with UPS from the whole OSAS population, examined in previous studies...
Repetitive transcranial magnetic stimulation for the treatment of negative symptoms in residual schizophrenia: rationale and design of a sham-controlled, randomized multicenter studyJoachim Cordes
Department of Psychiatry and Psychotherapy, Heinrich Heine University of Dusseldorf, Bergische Landstr 2, 40629 Düsseldorf, Germany
Eur Arch Psychiatry Clin Neurosci 259:S189-97. 2009..Main limitations of the trial are the potential influence of antipsychotic dosage changes and the difficulty to ensure adequate blinding...
Trimipramine in primary insomnia: results of a polysomnographic double-blind controlled studyD Riemann
Department of Psychiatry and Psychotherapy, University of Freiburg, Germany
Pharmacopsychiatry 35:165-74. 2002..However, due to the large intra- and interindividual variance in the parameters of interest before and during treatment a larger sample size would have been necessary to strengthen the validity of our findings...
Berry anthocyanins and anthocyanidins exhibit distinct affinities for the efflux transporters BCRP and MDR1A Dreiseitel
Department of Psychiatry, University of Regensburg, Regensburg, Germany
Br J Pharmacol 158:1942-50. 2009..Specifically, the role played by transport mechanisms at the intestinal and blood-brain barriers (BBB) is currently unknown...
Consensus for tinnitus patient assessment and treatment outcome measurement: Tinnitus Research Initiative meeting, Regensburg, July 2006B Langguth
Department of Psychiatry, University of Regensburg, Regensburg, Germany
Prog Brain Res 166:525-36. 2007..It is hoped that this will contribute towards better cooperation between research centres in finding and evaluating treatments for tinnitus by allowing better comparability between studies...
Clioquinol treatment in familiar early onset of Alzheimer's disease: a case reportB Ibach
Department of Psychiatry and Psychotherapy, University of Regensburg, Universitatsstrasse 84, Regensburg, Germany
Pharmacopsychiatry 38:178-9. 2005..In one case CSF-tau and beta-Amyloid (42/40) concentrations changed during CQ treatment...
High-frequency repetitive transcranial magnetic stimulation in schizophrenia: a combined treatment and neuroimaging studyG Hajak
Department of Psychiatry and Psychotherapy, University of Regensburg, Regensburg, Germany
Psychol Med 34:1157-63. 2004..In this context, disentangling of negative and depressive symptoms is of the utmost importance when understanding specific rTMS effects on schizophrenic symptoms...
