Axel Haferkamp

Summary

Affiliation: University of Heidelberg
Country: Germany

Publications

  1. ncbi request reprint Distribution of neuropeptide Y-containing nerves in the neurogenic and non-neurogenic detrusor
    Axel Haferkamp
    Department of Urology, University of Heidelberg, Heidelberg, Germany
    BJU Int 97:393-9. 2006
  2. ncbi request reprint Editorial comment on: Urethral reconstruction using the radial forearm free flap: experience in oncologic cases and gender reassignment
    Axel Haferkamp
    Department of Urology, University of Heidelberg, Heidelberg, Germany
    Eur Urol 52:554. 2007
  3. ncbi request reprint [Vesicovaginal fistulas]
    A Haferkamp
    Urologische Klinik, Universitatsklinikum, Heidelberg
    Urologe A 44:270-6. 2005
  4. ncbi request reprint Renal cell carcinoma with tumor thrombus extension into the vena cava: prospective long-term followup
    Axel Haferkamp
    Department of Urology, University of Heidelberg, Heidelberg, Germany
    J Urol 177:1703-8. 2007
  5. ncbi request reprint Increased expression of connexin 43 in the overactive neurogenic detrusor
    A Haferkamp
    Department of Urology, University of Bonn, Bonn, Germany
    Eur Urol 46:799-805. 2004
  6. ncbi request reprint Lack of ultrastructural detrusor changes following endoscopic injection of botulinum toxin type a in overactive neurogenic bladder
    A Haferkamp
    Department of Urology, University of Bonn, Bonn, Germany
    Eur Urol 46:784-91. 2004
  7. doi request reprint High nuclear Livin expression is a favourable prognostic indicator in renal cell carcinoma
    Axel Haferkamp
    Department of Urology, University of Heidelberg, Heidelberg, Germany
    BJU Int 102:1700-6. 2008
  8. ncbi request reprint [Ultrastructural changes in the aging bladder]
    A Haferkamp
    Urologische Universitätsklinik, Rupprecht Karls Universität Heidelberg
    Urologe A 43:527-34. 2004
  9. doi request reprint Prognostic factors influencing long-term survival of patients undergoing nephron-sparing surgery for nonmetastatic renal-cell carcinoma (RCC) with imperative indications
    Axel Haferkamp
    Department of Urology, University of Heidelberg, Heidelberg, Germany
    Ann Surg Oncol 17:544-51. 2010
  10. ncbi request reprint [Intravesical treatment of overactive bladder syndrome]
    A Haferkamp
    Urologische Klinik, Universitatsklinikum Heidelberg, Im Neuenheimer Feld 110, 69120, Heidelberg, Germany
    Urologe A 45:1283-8. 2006

Collaborators

Detail Information

Publications85

  1. ncbi request reprint Distribution of neuropeptide Y-containing nerves in the neurogenic and non-neurogenic detrusor
    Axel Haferkamp
    Department of Urology, University of Heidelberg, Heidelberg, Germany
    BJU Int 97:393-9. 2006
    ....
  2. ncbi request reprint Editorial comment on: Urethral reconstruction using the radial forearm free flap: experience in oncologic cases and gender reassignment
    Axel Haferkamp
    Department of Urology, University of Heidelberg, Heidelberg, Germany
    Eur Urol 52:554. 2007
  3. ncbi request reprint [Vesicovaginal fistulas]
    A Haferkamp
    Urologische Klinik, Universitatsklinikum, Heidelberg
    Urologe A 44:270-6. 2005
    ..e. Martius flap, omentum, peritoneum, when indicated. Using these surgical techniques, around 85% of women can be cured from their vesicovaginal fistula with a single operation...
  4. ncbi request reprint Renal cell carcinoma with tumor thrombus extension into the vena cava: prospective long-term followup
    Axel Haferkamp
    Department of Urology, University of Heidelberg, Heidelberg, Germany
    J Urol 177:1703-8. 2007
    ..We prospectively evaluated long-term survival in patients with renal cell carcinoma extending to the inferior vena cava...
  5. ncbi request reprint Increased expression of connexin 43 in the overactive neurogenic detrusor
    A Haferkamp
    Department of Urology, University of Bonn, Bonn, Germany
    Eur Urol 46:799-805. 2004
    ..The aim of this study was to prove this hypothesis...
  6. ncbi request reprint Lack of ultrastructural detrusor changes following endoscopic injection of botulinum toxin type a in overactive neurogenic bladder
    A Haferkamp
    Department of Urology, University of Bonn, Bonn, Germany
    Eur Urol 46:784-91. 2004
    ..The aim of this study was to evaluate the ultrastructural effects of Botulinum toxin type A injections on the human detrusor...
  7. doi request reprint High nuclear Livin expression is a favourable prognostic indicator in renal cell carcinoma
    Axel Haferkamp
    Department of Urology, University of Heidelberg, Heidelberg, Germany
    BJU Int 102:1700-6. 2008
    ..To assess the protein expression of Livin, an apoptosis inhibitor, in renal cell carcinoma (RCC) and to determine its prognostic relevance...
  8. ncbi request reprint [Ultrastructural changes in the aging bladder]
    A Haferkamp
    Urologische Universitätsklinik, Rupprecht Karls Universität Heidelberg
    Urologe A 43:527-34. 2004
    ....
  9. doi request reprint Prognostic factors influencing long-term survival of patients undergoing nephron-sparing surgery for nonmetastatic renal-cell carcinoma (RCC) with imperative indications
    Axel Haferkamp
    Department of Urology, University of Heidelberg, Heidelberg, Germany
    Ann Surg Oncol 17:544-51. 2010
    ....
  10. ncbi request reprint [Intravesical treatment of overactive bladder syndrome]
    A Haferkamp
    Urologische Klinik, Universitatsklinikum Heidelberg, Im Neuenheimer Feld 110, 69120, Heidelberg, Germany
    Urologe A 45:1283-8. 2006
    ..In conclusion, intravesical therapies can provide an alternative treatment for the management of overactive bladder...
  11. doi request reprint Gender-specific differences in cancer-specific survival after radical cystectomy for patients with urothelial carcinoma of the urinary bladder in pathologic tumor stage T4a
    Matthias May
    Department of Urology, St Elisabeth Klinikum, Straubing, Germany
    Urol Oncol 31:1141-7. 2013
    ..Bladder cancer (UCB) staged pT4a show heterogeneous outcome after radical cystectomy (RC). No risk model has been established to date. Despite gender-specific differences, no comparative studies exist for this tumor stage...
  12. doi request reprint Analysis of sex differences in cancer-specific survival and perioperative mortality following radical cystectomy: results of a large German multicenter study of nearly 2500 patients with urothelial carcinoma of the bladder
    Wolfgang Otto
    Department of Urology, Caritas St Josef Medical Centre, University of Regensburg, Landshuterstrasse 65, Regensburg, Germany
    Gend Med 9:481-9. 2012
    ..Although overall incidence is higher in men, cancer-specific survival (CSS) has been suggested to be lower in women. Although the former effect is attributed to greater exposure to carcinogens in men, the latter has not been elucidated...
  13. doi request reprint Low dosed interferon alpha augments the anti-tumor potential of histone deacetylase inhibition on prostate cancer cell growth and invasion
    Lukasz Hudak
    Department of Urology, Goethe University, Frankfurt am Main, Germany
    Prostate 72:1719-35. 2012
    ..Application of low-dosed IFNa to a VPA based regimen profoundly boosts the anti-tumor properties of VPA. The combined use of VPA and low-dosed IFNa may therefore be an innovative option in treating advanced prostate cancer...
  14. pmc Molecular targeting of prostate cancer cells by a triple drug combination down-regulates integrin driven adhesion processes, delays cell cycle progression and interferes with the cdk-cyclin axis
    Steffen Wedel
    Department of Urology, Goethe University, Frankfurt am Main, Germany
    BMC Cancer 11:375. 2011
    ....
  15. doi request reprint Prognostic value of melanoma-associated antigen A9 in renal cell carcinoma
    Gencay Hatiboglu
    Department of Urology, University of Heidelberg, Heidelberg, Germany
    Scand J Urol 47:311-22. 2013
    ..The aim of this study was to evaluate the prognostic relevance of melanoma-associated antigen (MAGE) A9 in renal cell carcinoma (RCC)...
  16. doi request reprint The cdk1-cyclin B complex is involved in everolimus triggered resistance in the PC3 prostate cancer cell line
    Igor Tsaur
    Department of Urology, Johann Wolfgang Goethe University, Frankfurt am Main, Germany
    Cancer Lett 313:84-90. 2011
    ..One reason for everolimus resistance may be up-regulation of the cdk1-cyclin B complex in prostate cancer cells, leading to enhanced progression towards G2/M...
  17. doi request reprint Critical analysis of simultaneous blockage of histone deacetylase and multiple receptor tyrosine kinase in the treatment of prostate cancer
    Steffen Wedel
    Department of Urology, Johann Wolfgang Goethe University, Frankfurt am Main, Germany
    Prostate 71:722-35. 2011
    ..We analyzed the effect of combining the multiple receptor tyrosine kinase inhibitor AEE788 and the histone deacetylase (HDAC) inhibitor valproic acid (VPA) on adhesion and growth properties of prostate cancer cell lines...
  18. pmc Resistance after chronic application of the HDAC-inhibitor valproic acid is associated with elevated Akt activation in renal cell carcinoma in vivo
    Eva Juengel
    Department of Urology, Johann Wolfgang Goethe University, Frankfurt am Main, Germany
    PLoS ONE 8:e53100. 2013
    ..We assume that chronic use of an HDAC-inhibitor is associated with (re)-activation of Akt, which may be involved in resistance development. Consequently, combined blockade of both HDAC and Akt may delay or prevent drug resistance in RCC...
  19. ncbi request reprint Pathological upstaging detected in radical cystectomy procedures is associated with a significantly worse tumour-specific survival rate for patients with clinical T1 urothelial carcinoma of the urinary bladder
    Matthias May
    Department of Urology, St Elisabeth Klinikum Straubing, Straubing, Germany
    Scand J Urol Nephrol 45:251-7. 2011
    ..This study aimed to evaluate the frequency and prognosis of upstaging in patients undergoing RC due to UCB...
  20. doi request reprint Is the body mass index a predictor of adverse outcome in prostate cancer after radical prostatectomy in a mid-European study population?
    Jesco Pfitzenmaier
    Department of Urology, Medical Centre, University of Heidelberg, Heidelberg, Germany
    BJU Int 103:877-82. 2009
    ..To evaluate the effect of body mass index (BMI) on the histopathological and clinical outcome in prostate cancer...
  21. doi request reprint Impact of combined HDAC and mTOR inhibition on adhesion, migration and invasion of prostate cancer cells
    Steffen Wedel
    Department of Urology, Johann Wolfgang Goethe University, Theodor Stern Kai 7, 60590, Frankfurt am Main, Germany
    Clin Exp Metastasis 28:479-91. 2011
    ..Ongoing studies are required to assess the relevance of VPA monotherapy versus VPA-RAD001 combination on tumor cell motility...
  22. doi request reprint The prostate cancer blocking potential of the histone deacetylase inhibitor LBH589 is not enhanced by the multi receptor tyrosine kinase inhibitor TKI258
    Stefan Vallo
    Department of Urology, Johann Wolfgang Goethe University, Interdisciplinary Science Building, Building 25, Room 204, Theodor Stern Kai 7, 60590 Frankfurt am Main, Germany
    Invest New Drugs 31:265-72. 2013
    ..Obviously, TKI258 did not enhance the sensitivity of prostate cancer cells towards an HDAC based regimen. Therefore, the LBH589/TKI258-combination probably does not provide an optimum strategy in fighting advanced prostate cancer...
  23. doi request reprint Acetylation of histone H3 prevents resistance development caused by chronic mTOR inhibition in renal cell carcinoma cells
    Eva Juengel
    Department of Urology, Johann Wolfgang Goethe University, Frankfurt am Main, Germany
    Cancer Lett 324:83-90. 2012
    ..siRNA experiments revealed that histone H3 acetylation is responsible for preserving drug sensitivity in RCCs...
  24. doi request reprint PSA density lower cutoff value as a tool to exclude pathologic upstaging in initially diagnosed unilateral prostate cancer: impact on hemiablative focal therapy
    Thomas Hofner
    Department of Urology, University of Heidelberg, Im Neuenheimer Feld 110, 69120, Heidelberg, Germany
    World J Urol 30:91-5. 2012
    ..To investigate prostate-specific antigen density as a predictor for pathologic upstaging in patients initially thought to have unilateral prostate cancer...
  25. doi request reprint Molecular heterogeneity of TFE3 activation in renal cell carcinomas
    Stephan Macher-Goeppinger
    Institute of Pathology, University of Heidelberg, Heidelberg, Germany
    Mod Pathol 25:308-15. 2012
    ..In turn, TFE3 overexpressing tumours show an aggressive behaviour and Xp11 translocation is only one of several possible underlying genomic alterations...
  26. doi request reprint HDAC inhibition suppresses bladder cancer cell adhesion to collagen under flow conditions
    Eva Juengel
    Department of Urology, Johann Wolfgang Goethe University, 60590 Frankfurt am Main, Germany
    Exp Biol Med (Maywood) 238:1297-304. 2013
    ..The effects were accompanied by distinct modifications of the integrin expression profile, which differ depending on the cell lines used. Application of VPA might be an innovative option to prevent bladder cancer dissemination. ..
  27. doi request reprint External validation of a risk model to predict recurrence-free survival after radical cystectomy in patients with pathological tumor stage T3N0 urothelial carcinoma of the bladder
    Matthias May
    Department of Urology, St Elisabeth Klinikum, Straubing, Germany
    J Urol 187:1210-4. 2012
    ..We present what is to our knowledge the first external validation of this risk model...
  28. doi request reprint External validation of postoperative nomograms for prediction of all-cause mortality, cancer-specific mortality, and recurrence in patients with urothelial carcinoma of the bladder
    Philipp Nuhn
    Department of Urology, Ludwig Maximilians Universitat, Munich, Germany
    Eur Urol 61:58-64. 2012
    ..The Bladder Cancer Research Consortium (BCRC) created nomograms to predict all-cause mortality (ACM), cancer-specific mortality (CSM), and recurrence after radical cystectomy (RC) for urothelial carcinoma of the bladder (UCB)...
  29. doi request reprint Positive surgical margins after radical prostatectomy: do they have an impact on biochemical or clinical progression?
    Jesco Pfitzenmaier
    Department of Urology, Medical Center, University of Heidelberg, Heidelberg, Germany
    BJU Int 102:1413-8. 2008
    ....
  30. doi request reprint Inhibitory effects of the HDAC inhibitor valproic acid on prostate cancer growth are enhanced by simultaneous application of the mTOR inhibitor RAD001
    Steffen Wedel
    Department of Urology, Johann Wolfgang Goethe University, Frankfurt am Main, Germany
    Life Sci 88:418-24. 2011
    ..To analyze the combined impact of the histone deacetylase (HDAC) inhibitor valproic acid (VPA) and the mammalian target of rapamycin (mTOR) inhibitor RAD001 on prostate cancer cell growth...
  31. doi request reprint HDAC inhibition delays cell cycle progression of human bladder cancer cells in vitro
    Stefan Vallo
    Department of Urology, Johann Wolfgang Goethe University, Frankfurt am Main, Germany
    Anticancer Drugs 22:1002-9. 2011
    ..Long-term application induced much stronger effects than did shorter application and should be considered when designing therapeutic strategies for treating bladder carcinoma...
  32. ncbi request reprint Vaporization of prostates of > or =80 mL using a potassium-titanyl-phosphate laser: midterm-results and comparison with prostates of <80 mL
    Jesco Pfitzenmaier
    Department of Urology, Medical Center, University of Heidelberg, Germany
    BJU Int 102:322-7. 2008
    ..To compare the safety and outcome of potassium-titanyl-phosphate (KTP) Greenlight (Laserscope, AMS, Minnetonka, MN, USA) vaporization for treating benign prostatic hyperplasia (BPH) in prostates of > or =80 vs <80 mL...
  33. doi request reprint Multicenter evaluation of the prognostic value of pT0 stage after radical cystectomy due to urothelial carcinoma of the bladder
    Matthias May
    Department of Urology, St Elisabeth Klinikum, Straubing LMU München, Munchen, Germany
    BJU Int 108:E278-83. 2011
    ..To evaluate the characteristics and long-term outcome of patients with pT0 stage after radical cystectomy (RC) for urothelial carcinoma of the urinary bladder (UCB)...
  34. doi request reprint Perinephric and renal sinus fat infiltration in pT3a renal cell carcinoma: possible prognostic differences
    Jens Bedke
    Department of Medical Biometry, University of Heidelberg, Heidelberg, Germany
    BJU Int 103:1349-54. 2009
    ..Perirenal fat invasion is differentiated into RS and PN fat infiltration, but not further classified for the prognosis...
  35. ncbi request reprint En bloc stapler ligation of the renal vascular pedicle during laparoscopic nephrectomy
    Stephan Buse
    Department of Urology and Paediatric Urology, University of Heidelberg, Medical School, Germany
    BJU Int 101:878-82. 2008
    ..To evaluate, in a prospective series of laparoscopic nephrectomies (LNs), the safety and feasibility of en bloc stapling for resection and occlusion of the vascular renal pedicle...
  36. doi request reprint The influence of body mass index on the long-term survival of patients with renal cell carcinoma after tumour nephrectomy
    Axel Haferkamp
    Department of Urology, University of Heidelberg, Germany
    BJU Int 101:1243-6. 2008
    ..To assess whether under- or overweight at the time of surgery has any effect on the survival of the patients with renal cell carcinoma (RCC), as obesity increases the risk of developing RCC...
  37. pmc Decoy receptor 3 is a prognostic factor in renal cell cancer
    Stephan Macher-Goeppinger
    Institute of Pathology, University of Heidelberg, Im Neuenheimer Feld 220, 69120 Heidelberg, Germany
    Neoplasia 10:1049-56. 2008
    ..Decoy receptor 3 (DcR3) is a soluble protein that binds to and inactivates the death ligand CD95L. Here, we studied a possible association between DcR3 expression and prognosis in patients with renal cell carcinomas (RCCs)...
  38. doi request reprint Association between the number of dissected lymph nodes during pelvic lymphadenectomy and cancer-specific survival in patients with lymph node-negative urothelial carcinoma of the bladder undergoing radical cystectomy
    Matthias May
    Department of Urology, St Elisabeth Klinikum Straubing, Straubing, Germany
    Ann Surg Oncol 18:2018-25. 2011
    ....
  39. ncbi request reprint Prognostic stratification of localized renal cell carcinoma by tumor size
    Jens Bedke
    Department of Urology, University of Heidelberg Medical School, Heidelberg, Germany
    J Urol 180:62-7. 2008
    ..0 cm to distinguish between T1 and T2 tumors. We reevaluated the optimal tumor size cutoff point that independently differentiates patient prognosis beyond the other accepted prognostic features...
  40. doi request reprint The enhancer of zeste homolog 2 gene contributes to cell proliferation and apoptosis resistance in renal cell carcinoma cells
    Nina Wagener
    German Cancer Research Center, Molecular Therapy of Virus Associated Cancers F065, Heidelberg, Germany
    Int J Cancer 123:1545-50. 2008
    ..Targeted inhibition of EZH2 could therefore represent a novel strategy to improve the therapeutic response of RCC...
  41. doi request reprint Intestinal reconstruction of the lower urinary tract as a prerequisite for renal transplantation
    Nenad Djakovic
    Department of Urology and Paediatric Urology, University of Heidelberg, Heidelberg, Germany
    BJU Int 103:1555-60. 2009
    ..It has the advantage of restoring the lower urinary tract before immunosuppressive therapy, and supplies the best possible reservoir for a transplanted kidney...
  42. ncbi request reprint Multislice computed tomography in planning nephron-sparing surgery in a prospective study with 76 patients: comparison of radiological and histopathological findings in the infiltration of renal structures
    Peter Hallscheidt
    Department of Diagnostic Radiology, University of Heidelberg, Germany
    J Comput Assist Tomogr 30:869-74. 2006
    ....
  43. doi request reprint Small renal cell carcinoma: oncological outcome with tumour size
    Sascha Pahernik
    Department of Urology, University of Heidelberg, Germany
    Scand J Urol Nephrol 45:432-5. 2011
    ..The aim of the study was to analyse oncological outcomes of patients with renal cell carcinoma (RCC) up to 4 cm in diameter...
  44. doi request reprint Preoperative hydronephrosis predicts advanced bladder cancer but is not an independent factor for cancer-specific survival after radical cystectomy
    Thomas Hofner
    Department of Urology, University of Heidelberg, Heidelberg, Germany
    Urol Int 86:25-30. 2011
    ....
  45. doi request reprint Risk factors and clinical management of haemorrhage after open nephron-sparing surgery
    Johannes Huber
    Department of Urology, University of Heidelberg, Heidelberg, Germany
    BJU Int 106:1488-93. 2010
    ..To identify risk factors for relevant haemorrhage after open nephron-sparing surgery (NSS) for renal cell carcinoma, and to evaluate its clinical management...
  46. doi request reprint Expression and prognostic relevance of the death receptor CD95 (Fas/APO1) in renal cell carcinomas
    Stephan Macher-Goeppinger
    Institute of Pathology, University of Heidelberg, Germany
    Cancer Lett 301:203-11. 2011
    ..In conclusion, high CD95 expression is a negative independent prognostic factor in RCCs which could be used to identify high-risk patients with a poor clinical prognosis...
  47. doi request reprint Impact of preoperative haemoglobin concentrations on the efficiency of KTP-laser vaporization of the prostate
    Stephan Buse
    Department of Urology, University of Heidelberg, Im Neuenheimer Feld 110, Heidelberg 69120, Germany
    World J Urol 27:405-9. 2009
    ..This reaction causes vaporization of the tissue. We tested whether preoperative haemoglobin concentrations (Hb) affect the efficiency of the 80 W KTP laser, thus affecting the energy applied...
  48. ncbi request reprint Adherens junctions of the human detrusor
    Nina Wagener
    Department of Urology, University of Heidelberg, Germany
    BJU Int 96:843-7. 2005
    ....
  49. doi request reprint Survival in prostate cancer patients > or = 70 years after radical prostatectomy and comparison to younger patients
    Jesco Pfitzenmaier
    Department of Urology, University of Heidelberg, INF 110, 69120 Heidelberg, Germany
    World J Urol 27:637-42. 2009
    ..The purpose of our study was to evaluate and compare the survival in prostate cancer (PCa) patients who underwent radical prostatectomy (RP) < and > or = 70 years...
  50. ncbi request reprint Resistance to the mTOR inhibitor temsirolimus alters adhesion and migration behavior of renal cell carcinoma cells through an integrin α5- and integrin β3-dependent mechanism
    Eva Juengel
    Department of Urology, Johann Wolfgang Goethe University, Frankfurt am Main, Germany
    Neoplasia 16:291-300. 2014
    ..Temsirolimus resistance is characterized by quantitative alterations of integrin α5 and β3 expression, coupled to functional changes of the integrin molecules, and forces a switch from RCC adhesion to RCC migration. ..
  51. doi request reprint Characterization and risk stratification of prostate cancer in patients undergoing radical cystoprostatectomy
    Stephan Buse
    Department of Urology, University of Heidelberg, Heidelberg, Germany
    Int J Urol 20:866-71. 2013
    ....
  52. pmc I publish in I edit? - do editorial board members of urologic journals preferentially publish their own scientific work?
    Jens Mani
    Department of Urology, Johann Wolfgang Goethe University, Frankfurt am Main, Germany
    PLoS ONE 8:e83709. 2013
    ....
  53. doi request reprint Combining open and laparoscopic surgery for partial nephrectomy
    Sascha Pahernik
    Department of Urology, University Clinic of Heidelberg, Heidelberg, Germany
    J Endourol 25:821-4. 2011
    ..We present a simple and easy to apply surgical approach for partial nephrectomy that combines open and laparoscopic surgery allowing for vascular control in technically challenging renal tumors and for reduction of ischemia time...
  54. ncbi request reprint Functional results 1 year after laser vaporization of the prostate: the impact of age
    Stephan Buse
    Department of Urology, University of Heidelberg Medical School, Heidelberg, Germany
    J Endourol 23:1339-42. 2009
    ..To test the hypothesis that age affects functional results after 80W photoselective vaporization of the prostate (PVP)...
  55. ncbi request reprint Thoraco-abdominal approach to large retroperitoneal tumours
    Stephan Buse
    Department of Urology, University of Heidelberg, Germany
    BJU Int 98:969-72. 2006
    ..To evaluate the thoraco-abdominal approach for resection of retroperitoneal tumours, as this approach is rarely used because, although exposure is excellent, morbidity is presumed to be increased...
  56. doi request reprint Prognostic variables for shockwave lithotripsy (SWL) treatment success: no impact of body mass index (BMI) using a third generation lithotripter
    Gencay Hatiboglu
    Department for Urology, University of Heidelberg, Heidelberg, Germany
    BJU Int 108:1192-7. 2011
    ....
  57. doi request reprint Selective transarterial embolization for posttraumatic renal hemorrhage: a second try is worthwhile
    Johannes Huber
    Department of Urology, University of Heidelberg, Heidelberg, Germany
    J Urol 185:1751-5. 2011
    ..Thus, the success rate of transarterial embolization should be maximized...
  58. ncbi request reprint Lymphovascular invasion is an independent predictor of oncological outcomes in patients with lymph node-negative urothelial bladder cancer treated by radical cystectomy: a multicentre validation trial
    Christian Bolenz
    Department of Urology, Mannheim Medical Centre, University of Heidelberg, Germany
    BJU Int 106:493-9. 2010
    ..To validate the association of lymphovascular invasion (LVI) with disease recurrence and cancer-specific survival (CSS) in a multicentre cohort of patients treated with radical cystectomy (RC) for urothelial bladder cancer (UBC)...
  59. ncbi request reprint Characterization of primary renal carcinoma cultures
    Elisabeth Sievers
    Department of Internal Medicine I, University of Bonn, Bonn, Germany
    Urol Int 79:235-43. 2007
    ....
  60. pmc HDAC-inhibition counteracts everolimus resistance in renal cell carcinoma in vitro by diminishing cdk2 and cyclin A
    Eva Juengel
    Department of Urology, Goethe University, Interdisciplinary Science Building, Building 25A, Room 404, Theodor Stern Kai 7, Frankfurt Main D 60590, Germany
    Mol Cancer 13:152. 2014
    ..Targeted therapies have improved therapeutic options of treating renal cell carcinoma (RCC). However, drug response is temporary due to resistance development...
  61. ncbi request reprint Chemokines involved in tumor promotion and dissemination in patients with renal cell cancer
    Igor Tsaur
    Department of Urology, Johann Wolfgang Goethe University, Frankfurt am Main, Germany igor
    Cancer Biomark 10:195-204. 2011
    ..Chemokines play a critical role in tumor initiation, progression, and metastasis and have been associated with poor prognosis in diverse malignancies. The prognostic impact of chemokines for renal cell cancer (RCC) remains to be defined...
  62. ncbi request reprint Preoperative staging of renal cell carcinoma with inferior vena cava thrombus using multidetector CT and MRI: prospective study with histopathological correlation
    Peter J Hallscheidt
    Department of Diagnostic Radiology, Heidelberg University, Im Neuenheimer Feld, Heidelberg, Germany
    J Comput Assist Tomogr 29:64-8. 2005
    ..To evaluate the accuracy of multidetector computed tomography (CT) and magnetic resonance imaging (MRI) in staging and estimating renal carcinomas with caval thrombus...
  63. doi request reprint Prognostic value of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) and TRAIL receptors in renal cell cancer
    Stephan Macher-Goeppinger
    Institute of Pathology, University of Heidelberg, Heidelberg, Germany
    Clin Cancer Res 15:650-9. 2009
    ..Here, we studied a possible association between the expression of TRAIL/TRAIL-Rs and the prognosis in patients with renal cell carcinomas (RCC)...
  64. doi request reprint Change of ureteral submucosal anti-reflux implantation into an intussuscepted ileal nipple valve as reflux protection in ureterosigmoidostomy
    Jesco Pfitzenmaier
    Department of Urology, University of Heidelberg, Heidelberg, Germany
    Urology 72:192-5. 2008
    ..Therefore, the implantation site of the ureters must be removed because of the risk of secondary malignancy with the consequences of a large colonic defect...
  65. ncbi request reprint Persistence of the synaptosomal-associated protein-25 cleavage product after intradetrusor botulinum toxin A injections in patients with myelomeningocele showing an inadequate response to treatment
    Heinrich Schulte-Baukloh
    Department of Urology, St Hedwig Hospital, Charite Medical School, Humboldt University Berlin, Germany
    BJU Int 100:1075-80. 2007
    ..This protein was detectable much longer after toxin treatment than published for rodent striated muscle, and thus could contribute to the clinically reported longer duration of the effectiveness of botox-A...
  66. ncbi request reprint Ureteric replacement with Meckel's diverticulum
    Judith Adams
    Department of Urology, University of Heidelberg, 69120 Heidelberg, Germany
    BJU Int 99:647-50. 2007
    ..To report on four patients with obstruction of the upper urinary tract due to severe ureteric strictures at different levels, in whom a Meckel's diverticulum was used for ureteric replacement...
  67. doi request reprint Evaluation and management of a patient with a bladder mass of uncertain etiology
    Jens Bedke
    Department of Urology, Eberhard Karls University Tubingen, Tubingen, Germany
    Nat Clin Pract Urol 5:509-14. 2008
    ..The patient refused further testing until tumor growth was detected at a scheduled appointment 5 months after presentation. She was referred to a urology department at this time...
  68. ncbi request reprint Repeated botulinum-A toxin injections in the treatment of myelodysplastic children and patients with spinal cord injuries with neurogenic bladder dysfunction
    Michael Akbar
    Department of Orthopaedic Surgery, University of Heidelberg, Heidelberg, Germany
    BJU Int 100:639-45. 2007
    ....
  69. pmc Publication of original research in urologic journals--a neglected orphan?
    Jens Mani
    Department of Urology, Johann Wolfgang Goethe University, Frankfurt am Main, Germany
    PLoS ONE 7:e52420. 2012
    ..There is no indication that such policy would be detrimental to a journal's impact factor...
  70. doi request reprint Combined targeting of the VEGFr/EGFr and the mammalian target of rapamycin (mTOR) signaling pathway delays cell cycle progression and alters adhesion behavior of prostate carcinoma cells
    Steffen Wedel
    Department of Urology, Johann Wolfgang Goethe University, Frankfurt am Main, Germany
    Cancer Lett 301:17-28. 2011
    ..Simultaneous targeting of mTOR and VEGFr/EGFr related pathways may offer a novel therapeutic strategy for prostate cancer treatment...
  71. doi request reprint Concomitant tumor and autoantigen vaccination supports renal cell carcinoma rejection
    Nicolás Herbert
    Department of Tumor Cell Biology, University Hospital of Surgery, University of Heidelberg, Germany
    J Immunol 185:902-16. 2010
    ..Activation of autoantigen-specific Th cells strongly supports tumor-specific Th cells and thereby CTL activation...
  72. doi request reprint Transarterial nephrectomy: the current status of experimental and clinical studies
    Jens Rassweiler
    Department of Urology, SLK Kliniken Heilbronn, University of Heidelberg, Germany
    J Endourol 22:767-82. 2008
    ..This paper focuses on the different principles of vaso-occlusion and further improvements of the technique such as capillary chemoembolization in experimental as well as clinical studies...
  73. doi request reprint Prognostic factors of papillary renal cell carcinoma: results from a multi-institutional series after pathological review
    Edwin Herrmann
    Department of Urology, University of Munster, Munster, Germany
    J Urol 183:460-6. 2010
    ..We examined papillary renal cell carcinoma prognostic variables and validated the 2002 UICC TNM staging system in a multicenter analysis...
  74. pmc Renal tumors and second primary pancreatic tumors: a relationship with clinical impact?
    Sascha A Müller
    Department of General, Visceral and Transplant Surgery, University of Heidelberg, Heidelberg, Germany
    Patient Saf Surg 6:18. 2012
    ..abstract:..
  75. ncbi request reprint A new form of noninvasive wound closure with a surgical zipper
    Patrick J Bastian
    Klinik und Poliklinik fur Urologie, Universitatsklinikum Bonn, Rheinische Friedrich Wilhelms Universitat, Bonn, Germany
    J Urol 169:1785-6. 2003
    ..We describe the use of Medizip (Nycomed Pharma GmbH, Ismaning, Germany), a new form of noninvasive skin closure system, in urological procedures...
  76. doi request reprint Editorial comment on: histological changes in the urothelium and suburothelium of human overactive bladder following intradetrusor injections of botulinum neurotoxin type A for the treatment of neurogenic or idiopathic detrusor overactivity
    Axel Haferkamp
    Eur Urol 53:1253. 2008
  77. ncbi request reprint Structural basis of neurogenic bladder dysfunction. III. Intrinsic detrusor innervation
    Axel Haferkamp
    Department of Pathology, Upstate Medical University, State University of New York, Syracuse, New York, USA
    J Urol 169:555-62. 2003
    ..We studied the ultrastructure of intrinsic detrusor innervation in long-standing neurogenic bladder dysfunction in the human...
  78. ncbi request reprint Modified ureterosigmoidostomy (Mainz Pouch II) in different age groups and with different techniques of ureteric implantation
    Patrick J Bastian
    Klinik und Poliklinik fur Urologie, Universitatsklinikum Bonn, Rheinische Friedrich Wilhelms Universitat Bonn, Germany
    BJU Int 94:345-9. 2004
    ..To examine the outcome of Mainz Pouch II urinary diversion in different age groups and with different techniques of ureteric implantation...
  79. ncbi request reprint The effect of tamsulosin on the resting tone and the contractile behaviour of the female urethra: a functional urodynamic study in healthy women
    Andre Reitz
    Neuro Urology, Swiss Paraplegic Center, Balgrist University Hospital, Forchstrasse 340, 8008 Zurich, Switzerland
    Eur Urol 46:235-40; discussion 240. 2004
    ....
  80. ncbi request reprint Structural basis of neurogenic bladder dysfunction. II. Myogenic basis of detrusor hyperreflexia
    Axel Haferkamp
    Department of Pathology, Upstate Medical University, State University of New York, Syracuse, New York, USA
    J Urol 169:547-54. 2003
    ..We describe the ultrastructure of detrusor smooth muscle in long-standing neurogenic bladder dysfunction in the human...
  81. ncbi request reprint Health-related quality-of-life following modified ureterosigmoidostomy (Mainz Pouch II) as continent urinary diversion
    Patrick J Bastian
    Klinik und Poliklinik fur Urologie, Universitatsklinikum Bonn, Rheinische Friedrich Wilhelms Universitat, Sigmund Freud Str 25, 53105 Bonn, Germany
    Eur Urol 46:591-7. 2004
    ..The purpose of this study was to estimate the health-related quality of life (HRQoL) following modified ureterosigmoidostomy (Mainz Pouch II) urinary diversion...
  82. ncbi request reprint Serological analysis of human renal cell carcinoma
    Gerard Devitt
    Department of Tumor Progression and Immune Defence, German Cancer Research Center, 69120 Heidelberg, Germany
    Int J Cancer 118:2210-9. 2006
    ..Sera from patients with non-malignant renal diseases or an autoimmune disease did not react with these 10 antigens...
  83. ncbi request reprint Cytotoxic markers and frequency predict functional capacity of natural killer cells infiltrating renal cell carcinoma
    Julia S Schleypen
    Institute of Molecular Immunology, GSF National Research Center for Environment and Health, Munich, Germany
    Clin Cancer Res 12:718-25. 2006
    ..Renal cell carcinoma harbors high numbers of infiltrating lymphocytes with apparent limited efficacy in tumor control. This study focused on the natural killer (NK) cells infiltrating renal cell carcinoma...
  84. ncbi request reprint Structural basis of neurogenic bladder dysfunction. I. Methods of prospective ultrastructural study and overview of the findings
    Ahmad Elbadawi
    Department of Pathology, Upstate Medical University, State University of New York, Syracuse, New York, USA
    J Urol 169:540-6. 2003
    ..We standardize procedures for ultrastructural study of detrusor smooth muscle and intrinsic nerves in neurogenic bladder dysfunction in the human, and present an overview of the findings...
  85. ncbi request reprint Facilitatory neuromodulative effect of duloxetine on pudendal motor neurons controlling the urethral pressure: a functional urodynamic study in healthy women
    Sönke Boy
    Neuro Urology, Swiss Paraplegic Center, Balgrist University Hospital, Zurich, Switzerland
    Eur Urol 50:119-25. 2006
    ....