Jochen Guck

Summary

Affiliation: University of Leipzig
Country: Germany

Publications

  1. pmc Optical deformability as an inherent cell marker for testing malignant transformation and metastatic competence
    Jochen Guck
    Institute for Soft Matter Physics, Department of Physics and Geosciences, University of Leipzig, 04103 Leipzig, Germany
    Biophys J 88:3689-98. 2005
  2. ncbi request reprint Quantifying the contribution of actin networks to the elastic strength of fibroblasts
    Revathi Ananthakrishnan
    Institute for Soft Matter Physics, University of Leipzig, 04103 Leipzig, Germany
    J Theor Biol 242:502-16. 2006
  3. ncbi request reprint Optical rheology of biological cells
    Falk Wottawah
    Institute for Soft Matter Physics, University of Leipzig, Linnestrasse 5, 04103 Leipzig, Germany
    Phys Rev Lett 94:098103. 2005
  4. ncbi request reprint High-throughput rheological measurements with an optical stretcher
    Bryan Lincoln
    Institut für Experimentelle Physik I, Universitat Leipzig, Linnestrasse 5, 04103 Leipzig, Germany
    Methods Cell Biol 83:397-423. 2007
  5. ncbi request reprint Deformability-based flow cytometry
    Bryan Lincoln
    Institute for Soft Matter Physics, University of Leipzig, Leipzig, Germany
    Cytometry A 59:203-9. 2004
  6. doi request reprint Oral cancer diagnosis by mechanical phenotyping
    Torsten W Remmerbach
    Department of Oral, Maxillofacial and Facial Plastic Surgery, University of Leipzig, Leipzig, Germany
    Cancer Res 69:1728-32. 2009
  7. ncbi request reprint Characterizing single suspended cells by optorheology
    Falk Wottawah
    Institute for Soft Matter Physics, Department of Physics and Geosciences, University of Leipzig, Linnestrasse 5, 04103 Leipzig, Germany
    Acta Biomater 1:263-71. 2005
  8. ncbi request reprint Excitation beyond the monochromatic laser limit: simultaneous 3-D confocal and multiphoton microscopy with a tapered fiber as white-light laser source
    Timo Betz
    Universitat Leipzig, Fakultat fur Physik und Geowissenschaften, Linnestrasse 5, 04103 Leipzig, Germany
    J Biomed Opt 10:054009. 2005
  9. ncbi request reprint Reconfigurable microfluidic integration of a dual-beam laser trap with biomedical applications
    Bryan Lincoln
    Institut für Experimentalphysik I, Universitat Leipzig, Linnestr 5, 04103, Leipzig, Germany
    Biomed Microdevices 9:703-10. 2007
  10. pmc Viscoelastic properties of individual glial cells and neurons in the CNS
    Yun Bi Lu
    Department of Pharmacology, School of Medicine, Zhejiang University, Yan An Road 353, Hangzhou 310031, China
    Proc Natl Acad Sci U S A 103:17759-64. 2006

Collaborators

  • Revathi Ananthakrishnan
  • Wolfgang Hartig
  • Timo Betz
  • Bryan Lincoln
  • Falk Wottawah
  • Stefan Schinkinger
  • Kristian Franze
  • Susanne Ebert
  • Kort Travis
  • Torsten W Remmerbach
  • Andreas Reichenbach
  • Frank Sauer
  • Yun Bi Lu
  • JOSEF KAS
  • Christian Wittekind
  • Julia Dietrich
  • Jens Grosche
  • Ortrud Uckermann
  • Serguei N Skatchkov
  • Detlev Schild
  • Christian Foja
  • Gerald Seifert
  • Er Qing Wei
  • Hartwig Wolburg
  • Paul Janmey
  • Christian Steinhäuser
  • Frank Kirchhoff
  • Karla Müller
  • Maren Romeyke
  • Harold M Erickson
  • Daniel Mitchell
  • Curt Bilby
  • Sydney Ulvick

Detail Information

Publications11

  1. pmc Optical deformability as an inherent cell marker for testing malignant transformation and metastatic competence
    Jochen Guck
    Institute for Soft Matter Physics, Department of Physics and Geosciences, University of Leipzig, 04103 Leipzig, Germany
    Biophys J 88:3689-98. 2005
    ..This suggests using optical deformability as an inherent cell marker for basic cell biological investigation and diagnosis of disease...
  2. ncbi request reprint Quantifying the contribution of actin networks to the elastic strength of fibroblasts
    Revathi Ananthakrishnan
    Institute for Soft Matter Physics, University of Leipzig, 04103 Leipzig, Germany
    J Theor Biol 242:502-16. 2006
    ....
  3. ncbi request reprint Optical rheology of biological cells
    Falk Wottawah
    Institute for Soft Matter Physics, University of Leipzig, Linnestrasse 5, 04103 Leipzig, Germany
    Phys Rev Lett 94:098103. 2005
    ..Mechanical stimuli on time scales of minutes trigger active structural responses...
  4. ncbi request reprint High-throughput rheological measurements with an optical stretcher
    Bryan Lincoln
    Institut für Experimentelle Physik I, Universitat Leipzig, Linnestrasse 5, 04103 Leipzig, Germany
    Methods Cell Biol 83:397-423. 2007
    ..This chapter details the setup and use of the microfluidic OS, the analysis and interpretation of data, and the results of a typical experiment...
  5. ncbi request reprint Deformability-based flow cytometry
    Bryan Lincoln
    Institute for Soft Matter Physics, University of Leipzig, Leipzig, Germany
    Cytometry A 59:203-9. 2004
    ..This connection between cellular function and cytoskeletal mechanical properties suggests using the deformability of cells as a novel inherent cell marker...
  6. doi request reprint Oral cancer diagnosis by mechanical phenotyping
    Torsten W Remmerbach
    Department of Oral, Maxillofacial and Facial Plastic Surgery, University of Leipzig, Leipzig, Germany
    Cancer Res 69:1728-32. 2009
    ..It could in principle be applied to any cancer to aid conventional diagnostic procedures...
  7. ncbi request reprint Characterizing single suspended cells by optorheology
    Falk Wottawah
    Institute for Soft Matter Physics, Department of Physics and Geosciences, University of Leipzig, Linnestrasse 5, 04103 Leipzig, Germany
    Acta Biomater 1:263-71. 2005
    ..This carries the potential for using the microfluidic optical stretcher to investigate cellular processes involving the cytoskeleton and to diagnose diseases related to cytoskeletal alterations...
  8. ncbi request reprint Excitation beyond the monochromatic laser limit: simultaneous 3-D confocal and multiphoton microscopy with a tapered fiber as white-light laser source
    Timo Betz
    Universitat Leipzig, Fakultat fur Physik und Geowissenschaften, Linnestrasse 5, 04103 Leipzig, Germany
    J Biomed Opt 10:054009. 2005
    ..By developing a coherent and intense laser source with spectral width comparable to a mercury lamp, we provide the flexibility to excite any desired fluorophore combination...
  9. ncbi request reprint Reconfigurable microfluidic integration of a dual-beam laser trap with biomedical applications
    Bryan Lincoln
    Institut für Experimentalphysik I, Universitat Leipzig, Linnestr 5, 04103, Leipzig, Germany
    Biomed Microdevices 9:703-10. 2007
    ..Possible applications include the cytological diagnosis of cancer and the gentle and marker-free sorting of stem cells from heterogeneous populations for therapeutic cell-based approaches in regenerative medicine...
  10. pmc Viscoelastic properties of individual glial cells and neurons in the CNS
    Yun Bi Lu
    Department of Pharmacology, School of Medicine, Zhejiang University, Yan An Road 353, Hangzhou 310031, China
    Proc Natl Acad Sci U S A 103:17759-64. 2006
    ....
  11. pmc Muller cells are living optical fibers in the vertebrate retina
    Kristian Franze
    Paul Flechsig Institute of Brain Research, Universitat Leipzig, Jahnallee 59, 04109 Leipzig, Germany
    Proc Natl Acad Sci U S A 104:8287-92. 2007
    ..This finding elucidates a fundamental feature of the inverted retina as an optical system and ascribes a new function to glial cells...