Jochen Guck

Summary

Affiliation: University of Leipzig
Country: Germany

Publications

  1. ncbi Optical deformability as an inherent cell marker for testing malignant transformation and metastatic competence
    Jochen Guck
    Institute for Soft Matter Physics, Department of Physics and Geosciences, University of Leipzig, 04103 Leipzig, Germany
    Biophys J 88:3689-98. 2005
  2. ncbi Quantifying the contribution of actin networks to the elastic strength of fibroblasts
    Revathi Ananthakrishnan
    Institute for Soft Matter Physics, University of Leipzig, 04103 Leipzig, Germany
    J Theor Biol 242:502-16. 2006
  3. ncbi Optical rheology of biological cells
    Falk Wottawah
    Institute for Soft Matter Physics, University of Leipzig, , 04103 Leipzig, Germany
    Phys Rev Lett 94:098103. 2005
  4. ncbi High-throughput rheological measurements with an optical stretcher
    Bryan Lincoln
    Institut für Experimentelle Physik I, Universitat Leipzig, Linnestrasse 5, 04103 Leipzig, Germany
    Methods Cell Biol 83:397-423. 2007
  5. ncbi Deformability-based flow cytometry
    Bryan Lincoln
    Institute for Soft Matter Physics, University of Leipzig, Leipzig, Germany
    Cytometry A 59:203-9. 2004
  6. ncbi Oral cancer diagnosis by mechanical phenotyping
    Torsten W Remmerbach
    Department of Oral, Maxillofacial and Facial Plastic Surgery, University of Leipzig, Leipzig, Germany
    Cancer Res 69:1728-32. 2009
  7. ncbi Characterizing single suspended cells by optorheology
    Falk Wottawah
    Institute for Soft Matter Physics, Department of Physics and Geosciences, University of Leipzig, , 04103 Leipzig, Germany
    Acta Biomater 1:263-71. 2005
  8. ncbi Excitation beyond the monochromatic laser limit: simultaneous 3-D confocal and multiphoton microscopy with a tapered fiber as white-light laser source
    Timo Betz
    Universitat Leipzig, Fakultat fur Physik und Geowissenschaften, Linnestrasse 5, 04103 Leipzig, Germany
    J Biomed Opt 10:054009. 2005
  9. ncbi Reconfigurable microfluidic integration of a dual-beam laser trap with biomedical applications
    Bryan Lincoln
    Institut für Experimentalphysik I, Universitat Leipzig, Linnestr 5, 04103, Leipzig, Germany
    Biomed Microdevices 9:703-10. 2007
  10. ncbi Viscoelastic properties of individual glial cells and neurons in the CNS
    Yun-bi Lu
    Department of Pharmacology, School of Medicine, Zhejiang University, Yan An Road 353, Hangzhou 310031, China
    Proc Natl Acad Sci U S A 103:17759-64. 2006

Collaborators

  • Revathi Ananthakrishnan
  • Wolfgang Hartig
  • Timo Betz
  • Bryan Lincoln
  • Falk Wottawah
  • Stefan Schinkinger
  • Kristian Franze
  • Susanne Ebert
  • Kort Travis
  • Torsten W Remmerbach
  • Andreas Reichenbach
  • Frank Sauer
  • Yun-bi Lu
  • Christian Wittekind
  • Julia Dietrich
  • Jens Grosche
  • Detlev Schild
  • Christian Foja
  • Ortrud Uckermann
  • Serguei N Skatchkov
  • Hartwig Wolburg
  • Er-qing Wei
  • Frank Kirchhoff
  • Gerald Seifert
  • Paul Janmey
  • Maren Romeyke
  • Curt Bilby
  • Sydney Ulvick
  • Harold M Erickson
  • Daniel Mitchell

Detail Information

Publications11

  1. ncbi Optical deformability as an inherent cell marker for testing malignant transformation and metastatic competence
    Jochen Guck
    Institute for Soft Matter Physics, Department of Physics and Geosciences, University of Leipzig, 04103 Leipzig, Germany
    Biophys J 88:3689-98. 2005
    ..This suggests using optical deformability as an inherent cell marker for basic cell biological investigation and diagnosis of disease...
  2. ncbi Quantifying the contribution of actin networks to the elastic strength of fibroblasts
    Revathi Ananthakrishnan
    Institute for Soft Matter Physics, University of Leipzig, 04103 Leipzig, Germany
    J Theor Biol 242:502-16. 2006
    ....
  3. ncbi Optical rheology of biological cells
    Falk Wottawah
    Institute for Soft Matter Physics, University of Leipzig, , 04103 Leipzig, Germany
    Phys Rev Lett 94:098103. 2005
    ..Mechanical stimuli on time scales of minutes trigger active structural responses...
  4. ncbi High-throughput rheological measurements with an optical stretcher
    Bryan Lincoln
    Institut für Experimentelle Physik I, Universitat Leipzig, Linnestrasse 5, 04103 Leipzig, Germany
    Methods Cell Biol 83:397-423. 2007
    ..This chapter details the setup and use of the microfluidic OS, the analysis and interpretation of data, and the results of a typical experiment...
  5. ncbi Deformability-based flow cytometry
    Bryan Lincoln
    Institute for Soft Matter Physics, University of Leipzig, Leipzig, Germany
    Cytometry A 59:203-9. 2004
    ..This could be used for the diagnosis of all diseases, and the investigation of all cellular processes, that affect the cytoskeleton...
  6. ncbi Oral cancer diagnosis by mechanical phenotyping
    Torsten W Remmerbach
    Department of Oral, Maxillofacial and Facial Plastic Surgery, University of Leipzig, Leipzig, Germany
    Cancer Res 69:1728-32. 2009
    ..It could in principle be applied to any cancer to aid conventional diagnostic procedures...
  7. ncbi Characterizing single suspended cells by optorheology
    Falk Wottawah
    Institute for Soft Matter Physics, Department of Physics and Geosciences, University of Leipzig, , 04103 Leipzig, Germany
    Acta Biomater 1:263-71. 2005
    ..This carries the potential for using the microfluidic optical stretcher to investigate cellular processes involving the cytoskeleton and to diagnose diseases related to cytoskeletal alterations...
  8. ncbi Excitation beyond the monochromatic laser limit: simultaneous 3-D confocal and multiphoton microscopy with a tapered fiber as white-light laser source
    Timo Betz
    Universitat Leipzig, Fakultat fur Physik und Geowissenschaften, Linnestrasse 5, 04103 Leipzig, Germany
    J Biomed Opt 10:054009. 2005
    ..By developing a coherent and intense laser source with spectral width comparable to a mercury lamp, we provide the flexibility to excite any desired fluorophore combination...
  9. ncbi Reconfigurable microfluidic integration of a dual-beam laser trap with biomedical applications
    Bryan Lincoln
    Institut für Experimentalphysik I, Universitat Leipzig, Linnestr 5, 04103, Leipzig, Germany
    Biomed Microdevices 9:703-10. 2007
    ..Possible applications include the cytological diagnosis of cancer and the gentle and marker-free sorting of stem cells from heterogeneous populations for therapeutic cell-based approaches in regenerative medicine...
  10. ncbi Viscoelastic properties of individual glial cells and neurons in the CNS
    Yun-bi Lu
    Department of Pharmacology, School of Medicine, Zhejiang University, Yan An Road 353, Hangzhou 310031, China
    Proc Natl Acad Sci U S A 103:17759-64. 2006
    ....
  11. ncbi Muller cells are living optical fibers in the vertebrate retina
    Kristian Franze
    Paul Flechsig Institute of Brain Research, Universitat Leipzig, Jahnallee 59, 04109 Leipzig, Germany
    Proc Natl Acad Sci U S A 104:8287-92. 2007
    ..This finding elucidates a fundamental feature of the inverted retina as an optical system and ascribes a new function to glial cells...