W Gu

Summary

Affiliation: University of Munich
Country: Germany

Publications

  1. ncbi request reprint LGI1: a gene involved in epileptogenesis and glioma progression?
    W Gu
    Institute of Human Genetics, School of Medicine, Ludwig Maximilians University, Goethestrasse 29, 80336 Munich, Germany
    Neurogenetics 6:59-66. 2005
  2. ncbi request reprint Reversal of terminal differentiation mediated by p107 in Rb-/- muscle cells
    J W Schneider
    Department of Cardiology, Children s Hospital, Harvard Medical School, Boston, MA 02115
    Science 264:1467-71. 1994
  3. ncbi request reprint Targeted disruption of the melanocortin-4 receptor results in obesity in mice
    D Huszar
    Millennium Pharmaceuticals, Inc, Cambridge, Massachusetts 02139, USA
    Cell 88:131-41. 1997
  4. ncbi request reprint Deacetylation of p53 modulates its effect on cell growth and apoptosis
    J Luo
    Institute of Cancer Genetics, and Department of Pathology, College of Physicians and Surgeons, Columbia University, New York, New York 10032, USA
    Nature 408:377-81. 2000
  5. ncbi request reprint Differential association of products of alternative transcripts of the candidate tumor suppressor ING1 with the mSin3/HDAC1 transcriptional corepressor complex
    D Skowyra
    Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, Texas 77030, USA
    J Biol Chem 276:8734-9. 2001

Collaborators

  • D Skowyra
  • J Luo
  • D Huszar
  • A V Gudkov
  • J Qin
  • N Neznanov
  • M Zeremski
  • C A Hauser
  • M Uesugi
  • M Li
  • Y Choi
  • A Shiloh
  • D Chen
  • F Su
  • J W Schneider
  • J H Dunmore
  • P Burn
  • L A Campfield
  • V Fairchild-Huntress
  • R D Cone
  • C A Lynch
  • Q Fang
  • R A Kesterson
  • F J Smith
  • F Lee
  • B A Boston
  • L R Berkemeier
  • B Nadal-Ginard
  • L Zhu
  • V Mahdavi

Detail Information

Publications5

  1. ncbi request reprint LGI1: a gene involved in epileptogenesis and glioma progression?
    W Gu
    Institute of Human Genetics, School of Medicine, Ludwig Maximilians University, Goethestrasse 29, 80336 Munich, Germany
    Neurogenetics 6:59-66. 2005
    ..We also propose that the evidence supporting the tumor suppressor role of LGI1 in malignant gliomas is weak and that further work is necessary to establish LGI1 role in glial cells...
  2. ncbi request reprint Reversal of terminal differentiation mediated by p107 in Rb-/- muscle cells
    J W Schneider
    Department of Cardiology, Children s Hospital, Harvard Medical School, Boston, MA 02115
    Science 264:1467-71. 1994
    ..Thus, although p107 could substitute for Rb as a cofactor for differentiation, it could not maintain the terminally differentiated state in Rb-/- myotubes...
  3. ncbi request reprint Targeted disruption of the melanocortin-4 receptor results in obesity in mice
    D Huszar
    Millennium Pharmaceuticals, Inc, Cambridge, Massachusetts 02139, USA
    Cell 88:131-41. 1997
    ..Our data identify a novel signaling pathway in the mouse for body weight regulation and support a model in which the primary mechanism by which agouti induces obesity is chronic antagonism of the MC4-R...
  4. ncbi request reprint Deacetylation of p53 modulates its effect on cell growth and apoptosis
    J Luo
    Institute of Cancer Genetics, and Department of Pathology, College of Physicians and Surgeons, Columbia University, New York, New York 10032, USA
    Nature 408:377-81. 2000
    ..These results show that deacetylation and functional interactions by the PID/MTA2-associated NuRD complex may represent an important pathway to regulate p53 function...
  5. ncbi request reprint Differential association of products of alternative transcripts of the candidate tumor suppressor ING1 with the mSin3/HDAC1 transcriptional corepressor complex
    D Skowyra
    Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, Texas 77030, USA
    J Biol Chem 276:8734-9. 2001
    ..Our data provide basis for a p33(ING1b)-specific molecular mechanism for the function of the ING1 locus...