Ruth Gruemmer

Summary

Affiliation: University of Essen
Country: Germany

Publications

  1. ncbi request reprint Gap junction connexin genes cx26 and cx43 are differentially regulated by ovarian steroid hormones in rat endometrium
    R Grummer
    Institute of Anatomy, University Hospital, Essen, Germany
    Endocrinology 140:2509-16. 1999
  2. ncbi request reprint Characteristic growth of human choriocarcinoma xenografts in nude mice
    R Grummer
    Institute of Anatomy, University Hospital, Essen, 45122, Germany
    Placenta 20:547-53. 1999
  3. ncbi request reprint Peritoneal endometriosis: validation of an in-vivo model
    R Grummer
    Institute of Anatomy, University Hospital Essen, 45122 Essen, Germany
    Hum Reprod 16:1736-43. 2001
  4. ncbi request reprint Different regulatory pathways of endometrial connexin expression: preimplantation hormonal-mediated pathway versus embryo implantation-initiated pathway
    R Grummer
    Institute of Anatomy, University Hospital, 45122 Essen, Germany
    Biol Reprod 71:273-81. 2004
  5. ncbi request reprint Regulation of gene expression in endothelial cells: the role of human follicular fluid
    R Gruemmer
    Department of Anatomy, University of Essen, Hufelandstr 55, D 45122, Essen, Germany
    J Mol Endocrinol 34:37-46. 2005
  6. pmc Regulation of soluble vascular endothelial growth factor receptor (sFlt-1/sVEGFR-1) expression and release in endothelial cells by human follicular fluid and granulosa cells
    Ruth Gruemmer
    Institute of Anatomy, University Hospital, Essen, Germany
    Reprod Biol Endocrinol 3:57. 2005
  7. ncbi request reprint Animal models in endometriosis research
    Ruth Grümmer
    Institute of Anatomy, University Hospital Essen, Essen, Germany
    Hum Reprod Update 12:641-9. 2006
  8. doi request reprint Progestins inhibit expression of MMPs and of angiogenic factors in human ectopic endometrial lesions in a mouse model
    Verena Mönckedieck
    Institute of Molecular Biology, University Hospital Essen, 45122 Essen, Germany
    Mol Hum Reprod 15:633-43. 2009
  9. pmc Replacement of connexin43 by connexin26 in transgenic mice leads to dysfunctional reproductive organs and slowed ventricular conduction in the heart
    Elke Winterhager
    Institut fur Anatomie, Universitat Duisburg Essen, 45122 Essen, Germany
    BMC Dev Biol 7:26. 2007
  10. ncbi request reprint Expression and regulation of estrogen-converting enzymes in ectopic human endometrial tissue
    Sabine Fechner
    Institute of Anatomy, University Hospital Essen, Universitat Duisburg Essen, Essen, Germany
    Fertil Steril 88:1029-38. 2007

Collaborators

Detail Information

Publications14

  1. ncbi request reprint Gap junction connexin genes cx26 and cx43 are differentially regulated by ovarian steroid hormones in rat endometrium
    R Grummer
    Institute of Anatomy, University Hospital, Essen, Germany
    Endocrinology 140:2509-16. 1999
    ....
  2. ncbi request reprint Characteristic growth of human choriocarcinoma xenografts in nude mice
    R Grummer
    Institute of Anatomy, University Hospital, Essen, 45122, Germany
    Placenta 20:547-53. 1999
    ..This model can be useful in investigating the cell biological mechanisms of trophoblast vessel invasion and replacement of the endothelium by trophoblast cells...
  3. ncbi request reprint Peritoneal endometriosis: validation of an in-vivo model
    R Grummer
    Institute of Anatomy, University Hospital Essen, 45122 Essen, Germany
    Hum Reprod 16:1736-43. 2001
    ..To establish an appropriate in-vivo model to evaluate new therapeutic strategies we validated the nude mouse model for the intraperitoneal cultivation of human endometrial tissue...
  4. ncbi request reprint Different regulatory pathways of endometrial connexin expression: preimplantation hormonal-mediated pathway versus embryo implantation-initiated pathway
    R Grummer
    Institute of Anatomy, University Hospital, 45122 Essen, Germany
    Biol Reprod 71:273-81. 2004
    ....
  5. ncbi request reprint Regulation of gene expression in endothelial cells: the role of human follicular fluid
    R Gruemmer
    Department of Anatomy, University of Essen, Hufelandstr 55, D 45122, Essen, Germany
    J Mol Endocrinol 34:37-46. 2005
    ....
  6. pmc Regulation of soluble vascular endothelial growth factor receptor (sFlt-1/sVEGFR-1) expression and release in endothelial cells by human follicular fluid and granulosa cells
    Ruth Gruemmer
    Institute of Anatomy, University Hospital, Essen, Germany
    Reprod Biol Endocrinol 3:57. 2005
    ..On the other hand, soluble VEGF receptor-1 (sFlt-1) produced by endothelial cells acts as a negative modulator for the bioavailability of VEGF. However, the regulation of sFlt-1 production remains to be determined...
  7. ncbi request reprint Animal models in endometriosis research
    Ruth Grümmer
    Institute of Anatomy, University Hospital Essen, Essen, Germany
    Hum Reprod Update 12:641-9. 2006
    ....
  8. doi request reprint Progestins inhibit expression of MMPs and of angiogenic factors in human ectopic endometrial lesions in a mouse model
    Verena Mönckedieck
    Institute of Molecular Biology, University Hospital Essen, 45122 Essen, Germany
    Mol Hum Reprod 15:633-43. 2009
    ..In parallel, microvessel density was slightly suppressed by progestins, whereas number of stabilized vessels increased. Thus, progestins regulate factors important for the establishment and maintenance of ectopic endometrial lesions...
  9. pmc Replacement of connexin43 by connexin26 in transgenic mice leads to dysfunctional reproductive organs and slowed ventricular conduction in the heart
    Elke Winterhager
    Institut fur Anatomie, Universitat Duisburg Essen, 45122 Essen, Germany
    BMC Dev Biol 7:26. 2007
    ..In order to further distinguish unique from general functions of connexin43, we have generated mice in which the coding region of connexin43 was replaced by that of connexin26...
  10. ncbi request reprint Expression and regulation of estrogen-converting enzymes in ectopic human endometrial tissue
    Sabine Fechner
    Institute of Anatomy, University Hospital Essen, Universitat Duisburg Essen, Essen, Germany
    Fertil Steril 88:1029-38. 2007
    ..To investigate the regulation of estrogen-converting enzymes in human ectopic endometrial tissue...
  11. doi request reprint Blastocyst-mediated induction of endometrial connexins: an inflammatory response?
    Ruth Grümmer
    Institute of Molecular Biology, University Hospital, University Duisburg Essen, Germany
    J Reprod Immunol 90:9-13. 2011
    ....
  12. doi request reprint Hormone-induced delayed ovulation affects early embryonic development
    Ann Kathrin Bittner
    Institute of Molecular Biology, University Hospital Essen, University Duisburg Essen, Essen, Germany
    Fertil Steril 95:2390-4. 2011
    ..To analyze the effects of delayed ovulation on embryonic development in mice, because intrafollicular oocyte development may be delayed during assisted reproductive technology (ART) treatment in humans...
  13. doi request reprint Screening for embryonic loss during in utero development of mice with a human 1.5 Tesla clinical MRI scanner
    Ruth Gruemmer
    Institute of Molecular Biology, University Hospital, Essen, Germany
    J Magn Reson Imaging 32:1158-65. 2010
    ..To establish in utero MRI-scanning of mouse implantation sites in a 1.5 Tesla whole-body human clinical scanner for evaluation of impaired implantation, placental or developmental defects due to genetic alterations...
  14. ncbi request reprint Congenital hypothyroid female pax8-deficient mice are infertile despite thyroid hormone replacement therapy
    Jens Mittag
    University Hospital Essen, Institute of Anatomy, Hufelandstrasse 55, 45122 Essen, Germany
    Endocrinology 148:719-25. 2007
    ....