Affiliation: University of Hamburg
- Expression of gamma-IFN responsive genes in scavenger receptor over-expressing monocytes is associated with xanthomatosisT Grewal
Hyperlipidemia and Atherosclerosis Research Group, Clinical Research Institute of Montreal, Quebec, Canada
Atherosclerosis 138:335-45. 1998..Our data suggest that the inflammatory effects of gamma-IFN signaling could play a role in foam cell formation and xanthomatosis...
- Annexin VI stimulates endocytosis and is involved in the trafficking of low density lipoprotein to the prelysosomal compartmentT Grewal
Medizinische Kernklinik und Poliklinik, Universitats Krankenhaus Eppendorf, Martinistr 52, 20246 Hamburg, Germany
J Biol Chem 275:33806-13. 2000..Thus, data presented in this study suggest that after stimulating endocytosis at the cell surface, annexin VI remains bound to endocytic vesicles to regulate entry of ligands into the prelysosomal compartment...
- Identification of a gamma-interferon-responsive element in the promoter of the human macrophage scavenger receptor A geneT Grewal
Hyperlipidemia and Atherosclerosis Research Group, Clinical Research Institute of Montreal, Montreal, Quebec, Canada
Arterioscler Thromb Vasc Biol 21:825-31. 2001..gamma-IFN-induced STAT1 activation, leading to increased SR-A expression, could therefore play an important role in the initial steps of foam cell formation and xanthomatosis...