G Gradl

Summary

Affiliation: University of Rostock
Country: Germany

Publications

  1. ncbi request reprint Efficiency of small-volume resuscitation in restoration of disturbed skeletal muscle microcirculation after soft-tissue trauma and haemorrhagic shock
    Philip Gierer
    Department of Trauma and Reconstructive Surgery, University of Rostock, Schillingallee 35, 18057 Rostock, Germany
    Langenbecks Arch Surg 389:40-5. 2004
  2. doi request reprint Fracture near press-on interlocking enhances callus mineralisation in a sheep midshaft tibia osteotomy model
    G Gradl
    Department for Trauma and Reconstructive Surgery, University of Rostock, Germany Electronic address
    Injury 45:S66-70. 2014
  3. doi request reprint Locking plate fixation of humeral head fractures with a telescoping screw. A comparative biomechanical study versus a standard plate
    Gertraud Gradl
    Department for Trauma Surgery, University of Aachen, Germany
    Injury 43:734-8. 2012
  4. ncbi request reprint Angular and sliding stable antegrade nailing (Targon PH) for the treatment of proximal humeral fractures
    Georg Gradl
    Department of Trauma and Reconstructive Surgery, University of Rostock, Schillingallee 35, 18055, Rostock, Germany
    Arch Orthop Trauma Surg 127:937-44. 2007
  5. ncbi request reprint Fractures of the distal radius treated with a nonbridging external fixation technique using multiplanar k-wires
    Georg Gradl
    Chirurgische Klinik und Poliklinik der Universität Rostock, Rostock, Germany
    J Hand Surg Am 30:960-8. 2005
  6. ncbi request reprint [Evaluation of sympathicolysis after continuous brachial plexus analgesia using laser Doppler flowmetry in patients suffering from CRPS I]
    G Gradl
    Chirurgische Klinik und Poliklinik, Abteilung für Unfall und Wiederherstellungschirurgie der Universität Rostock
    Anasthesiol Intensivmed Notfallmed Schmerzther 40:345-9. 2005
  7. ncbi request reprint Sympathetic dysfunction as a temporary phenomenon in acute posttraumatic CRPS I
    Georg Gradl
    Chirurgische Klinik und Poliklinik der Universität Rostock, Abteilung Unfall und Wiederherstellungschirurgie, Rostock, Germany
    Clin Auton Res 15:29-34. 2005
  8. doi request reprint [Fixation of distal radial fractures with the Targon DR nail]
    Georg Gradl
    Abteilung für Unfall und Wiederherstellungschirurgie, Chirurgische Klinik und Poliklinik der Universität Rostock, Rostock, Germany
    Oper Orthop Traumatol 21:472-83. 2009
  9. ncbi request reprint Quantification of C2 cervical spine rotatory fixation by X-ray, MRI and CT
    Georg Gradl
    Abteilung Unfall und Wiederherstellungschirurgie, Chirurgische Klinik und Poliklinik der Universität Rostock, Schillingallee 35, 81055, Rostock, Germany
    Eur Radiol 15:376-82. 2005
  10. ncbi request reprint [Radio-radial external fixation in the treatment of distal radius fractures allows for free wrist motion]
    G Gradl
    Abteilung für Unfall und Wiederherstellungschirurgie, Chirurgische Klinik und Poliklinik der Universität Rostock
    Zentralbl Chir 128:1014-9. 2003

Detail Information

Publications38

  1. ncbi request reprint Efficiency of small-volume resuscitation in restoration of disturbed skeletal muscle microcirculation after soft-tissue trauma and haemorrhagic shock
    Philip Gierer
    Department of Trauma and Reconstructive Surgery, University of Rostock, Schillingallee 35, 18057 Rostock, Germany
    Langenbecks Arch Surg 389:40-5. 2004
    ..Herein, we report on the efficiency of small-volume resuscitation to improve compromised perfusion of traumatised skeletal muscle tissue in shock...
  2. doi request reprint Fracture near press-on interlocking enhances callus mineralisation in a sheep midshaft tibia osteotomy model
    G Gradl
    Department for Trauma and Reconstructive Surgery, University of Rostock, Germany Electronic address
    Injury 45:S66-70. 2014
    ..Fracture near press-on interlocking reduces share forces directly at the fracture site and is hypothesised to enhance callus mineralisation. A sheep model of midshaft tibia osteotomies evaluates the technique...
  3. doi request reprint Locking plate fixation of humeral head fractures with a telescoping screw. A comparative biomechanical study versus a standard plate
    Gertraud Gradl
    Department for Trauma Surgery, University of Aachen, Germany
    Injury 43:734-8. 2012
    ..Screw in screw fixation of the greater tubercle may reduce the rate of cranial displacement...
  4. ncbi request reprint Angular and sliding stable antegrade nailing (Targon PH) for the treatment of proximal humeral fractures
    Georg Gradl
    Department of Trauma and Reconstructive Surgery, University of Rostock, Schillingallee 35, 18055, Rostock, Germany
    Arch Orthop Trauma Surg 127:937-44. 2007
    ..The purpose of this study was to evaluate the functional outcome and the complication rate of an angular and sliding stable antegrade interlocking nail for the treatment of displaced proximal humeral fractures...
  5. ncbi request reprint Fractures of the distal radius treated with a nonbridging external fixation technique using multiplanar k-wires
    Georg Gradl
    Chirurgische Klinik und Poliklinik der Universität Rostock, Rostock, Germany
    J Hand Surg Am 30:960-8. 2005
    ..A method of nonbridging hybrid fixation of distal radius fractures facilitates fracture reduction and allows for free wrist movement...
  6. ncbi request reprint [Evaluation of sympathicolysis after continuous brachial plexus analgesia using laser Doppler flowmetry in patients suffering from CRPS I]
    G Gradl
    Chirurgische Klinik und Poliklinik, Abteilung für Unfall und Wiederherstellungschirurgie der Universität Rostock
    Anasthesiol Intensivmed Notfallmed Schmerzther 40:345-9. 2005
    ..The aim of this study was to evaluate continuous brachial plexus analgesia in terms of pain relief and sympathicolysis in patients suffering from CRPS I...
  7. ncbi request reprint Sympathetic dysfunction as a temporary phenomenon in acute posttraumatic CRPS I
    Georg Gradl
    Chirurgische Klinik und Poliklinik der Universität Rostock, Abteilung Unfall und Wiederherstellungschirurgie, Rostock, Germany
    Clin Auton Res 15:29-34. 2005
    ..Repeated measurements were used to detect changes in peripheral sympathetic function during the course of the disease...
  8. doi request reprint [Fixation of distal radial fractures with the Targon DR nail]
    Georg Gradl
    Abteilung für Unfall und Wiederherstellungschirurgie, Chirurgische Klinik und Poliklinik der Universität Rostock, Rostock, Germany
    Oper Orthop Traumatol 21:472-83. 2009
    ..Anatomic restoration and intramedullary fixation of distal radial fractures using a hybrid between plate and nail (Targon DR). The technique provides a less invasive operative approach from radial...
  9. ncbi request reprint Quantification of C2 cervical spine rotatory fixation by X-ray, MRI and CT
    Georg Gradl
    Abteilung Unfall und Wiederherstellungschirurgie, Chirurgische Klinik und Poliklinik der Universität Rostock, Schillingallee 35, 81055, Rostock, Germany
    Eur Radiol 15:376-82. 2005
    ..Quantification of upper cervical spine malrotation was possible on plain radiographs using the SPD and a rotation coefficient. MRI and CT were equally successful in the assessment of C2 malrotation...
  10. ncbi request reprint [Radio-radial external fixation in the treatment of distal radius fractures allows for free wrist motion]
    G Gradl
    Abteilung für Unfall und Wiederherstellungschirurgie, Chirurgische Klinik und Poliklinik der Universität Rostock
    Zentralbl Chir 128:1014-9. 2003
    ..Immobilisation of the wrist joint is a further disadvantage. An extraarticular hybrid fixation of distal radius fractures was introduced that facilitates fracture reduction, safe retention and allows for free wrist movement...
  11. pmc Is locking nailing of humeral head fractures superior to locking plate fixation?
    G Gradl
    Department of Trauma and Reconstructive Surgery, University of Rostock, Schillingallee 35, D 18055, Rostock, Germany
    Clin Orthop Relat Res 467:2986-93. 2009
    ..We observed no differences between the two groups. Stabilization of displaced proximal humeral fractures with either an angular stable intramedullary or an extramedullary implant seems suitable with both surgical treatment options...
  12. ncbi request reprint [Acute CRPS I (morbus sudeck) following distal radial fractures--methods for early diagnosis]
    G Gradl
    Chirurgische Klinik und Poliklinik, Abteilung für Unfall und Wiederherstellungschirurgie der Universität Rostock
    Zentralbl Chir 128:1020-6. 2003
    ..The incidence of CRPS I in patients at risk and the diagnostic value of clinical evaluation, radiography and thermography in the early posttraumatic phase are analysed...
  13. ncbi request reprint [Complex proximal humerus fractures--management with a humeral head prosthesis? Clinical and radiological results of a prospective study]
    P Gierer
    Abteilung für Unfall und Wiederherstellungschirurgie, Klinik und Poliklinik für Chirurgie, Universitat, Schillingallee 35, 18055 Rostock
    Orthopade 35:834-40. 2006
    ..The present study was undertaken to evaluate the results of primary hemiarthroplasty in the treatment of proximal humerus fractures with a modular prosthesis (EPOCA, Fa. Argomedical, Gifhorn, Germany)...
  14. doi request reprint [Treatment of complicated proximal segmental tibia fractures with the less invasive stabilization locking plate system]
    M Beck
    Abteilung für Unfall und Wiederherstellungschirurgie, Klinik und Poliklinik für Chirurgie, Schillingallee 35, 18057 Rostock, Deutschland
    Unfallchirurg 111:493-8. 2008
    ..This clinical study was designed to clarify whether Tibia-LISS is a suitable implant for this type of fracture...
  15. doi request reprint Which is the ideal point of time to perform intraoperative 3D imaging in dorsal stabilisation of thoracolumbar spine fractures? A matched pair analysis
    M Beck
    Dept of Trauma and Reconstructive Surgery, University of Rostock, Schillingallee 35, D 18057 Rostock, Germany
    Injury 41:996-1001. 2010
    ..The aim of this study was to find out the optimal point of time to perform an intraoperative 3D scan and if a postoperative computed tomography is dispensable...
  16. ncbi request reprint Exaggeration of tissue trauma induces signs and symptoms of acute CRPS I, however displays distinct differences to experimental CRPS II
    Georg Gradl
    Department of Trauma and Reconstructive Surgery, University of Rostock, Germany
    Neurosci Lett 402:267-72. 2006
    ..Pain perception displays differences to that in CRPS II. Apoptosis turns out to be a distinctive marker for CRPS, warranting further evaluation in clinical studies...
  17. doi request reprint [Intraoperative control of pedicle screw position using three-dimensional fluoroscopy. A prospective study in thoracolumbar fractures]
    M Beck
    Abteilung für Unfall und Wiederherstellungschirurgie, Universitätsklinikum Rostock AöR
    Z Orthop Unfall 147:37-42. 2009
    ..However, only a computer tomographic scan can show the exact position of the screws. This study was undertaken to assess the reliability of intraoperative three-dimensional imaging (3-D) to view screw positions...
  18. ncbi request reprint [The femoral neck fracture in the elderly patient - cemented or cementless hip arthroplasty?]
    P Gierer
    Klinik und Poliklinik für Chirurgie, Abteilung für Unfall und Wiederherstellungschirurgie, Universitat Rostock, Germany
    Zentralbl Chir 127:514-8. 2002
    ..Patients with cardiopulmonary risk factors, however, may profit from cementless hip arthroplasty to avoid the well known cardiodepression during surgery...
  19. pmc Benefit and accuracy of intraoperative 3D-imaging after pedicle screw placement: a prospective study in stabilizing thoracolumbar fractures
    Markus Beck
    Department of Trauma and Reconstructive Surgery, University of Rostock, Schillingallee 35, 18057, Rostock, Germany
    Eur Spine J 18:1469-77. 2009
    ..But intraoperative evaluation of the 3D scans resulted in a primary revision rate of 2.7% of the pedicle screws and we could lower the secondary revision rate to 0.5%...
  20. doi request reprint Intraoperative position determination of bone cement trocars by 3-dimensional imaging in patients with osteoporotic vertebral fractures
    Markus Beck
    Department of Trauma and Reconstructive Surgery, University of Rostock, Rostock, Germany
    J Spinal Disord Tech 23:e16-23. 2010
    ..A prospective diagnostic study to evaluate the use of intraoperative 3-dimensional (3D) imaging...
  21. doi request reprint Microcirculatory sequelae of the rotator cuff after antegrade nailing in proximal humerus fracture
    Philip Gierer
    Department of Trauma and Reconstructive Surgery, University of Rostock, Schillingallee 35, 18057, Rostock, Germany
    Arch Orthop Trauma Surg 130:687-91. 2010
    ..Since the surgical procedure in antegrade humeral nailing requires a split of the supraspinatus tendon, the question arises whether the surgical approach causes microcirculatory dysfunction of the tendon...
  22. ncbi request reprint Sublethal trauma model with systemic endotoxemia for the study of microcirculatory disorders after the second hit
    Philip Gierer
    Institute for Experimental Surgery, University of Rostock, Rostock, Germany
    J Surg Res 147:68-74. 2008
    ..We present an experimental animal model combining initial standardized soft tissue trauma to the left hindlimb of rats with subsequent sublethal systemic endotoxemia...
  23. ncbi request reprint Partial weight bearing after surgery for fractures of the lower extremity--is it achievable?
    Attila Vasarhelyi
    Abteilung für Unfall und Wiederherstellungschirurgie Klinik und Poliklinik für Chirurgie, Universitat Rostock, Schillingallee 35, 18055 Rostock, Germany
    Gait Posture 23:99-105. 2006
    ..006 and 0.037). This study implies that the conventional concept of postoperative partial weight bearing starting from 200 N and a stepwise increase of the load level until full weight bearing is not valid during clinical practice...
  24. ncbi request reprint Introduction of a new interlocked intramedullary nailing device for stabilization of critically sized femoral defects in the rat: A combined biomechanical and animal experimental study
    Matthias Schoen
    Institute for Experimental Surgery, University of Rostock, 18055 Rostock, Germany
    J Orthop Res 26:184-9. 2008
    ..Nevertheless, our data corroborate the necessity of an internal fixation device with sufficient axial and rotational stability...
  25. ncbi request reprint Continuous intra-arterial application of substance P induces signs and symptoms of experimental complex regional pain syndrome (CRPS) such as edema, inflammation and mechanical pain but no thermal pain
    G Gradl
    Institute for Experimental Surgery, University of Rostock, Schillingallee 69a, 18055 Rostock, Germany
    Neuroscience 148:757-65. 2007
    ....
  26. ncbi request reprint Selective cyclooxygenase-2 inhibition reverses microcirculatory and inflammatory sequelae of closed soft-tissue trauma in an animal model
    Philip Gierer
    Departments of Experimental Surgery, University of Rostock, Schillingallee 70, 18055 Rostock, Germany
    J Bone Joint Surg Am 87:153-60. 2005
    ....
  27. doi request reprint Frequencies of polymorphisms in cytokines, neurotransmitters and adrenergic receptors in patients with complex regional pain syndrome type I after distal radial fracture
    Philipp Herlyn
    Department of Trauma and Reconstructive Surgery daggerInstitute of Immunology, University of Rostock, Germany
    Clin J Pain 26:175-81. 2010
    ..Different theories have been put forward to explain the pathogenesis of this disease, some including genetic models. The aim of this study was to find a possible genetic involvement in the occurrence of CRPS I...
  28. ncbi request reprint Stabilization of proximal humeral fractures with an angular and sliding stable antegrade locking nail (Targon PH)
    Th W F Mittlmeier
    Chirugische Klinik und Poliklinik der Universitaet Rostock, Abteilung für Unfall und Wiederherstellungschirugie, Rostock, Germany
    J Bone Joint Surg Am 85:136-46. 2003
  29. doi request reprint Ebselen reduces inflammation and microvascular perfusion failure after blunt skeletal muscle injury of the rat
    Philip Gierer
    Institute of Experimental Surgery, Department of Trauma and Reconstructive Surgery, University of Rostock, Rostock, Germany
    J Trauma 68:853-8. 2010
    ....
  30. ncbi request reprint Supernatant of traumatized muscle induces inflammation and pain, but not microcirculatory perfusion failure and apoptotic cell death
    Georg Gradl
    Department of Experimental Surgery, University of Rostock, 18055 Rostock, Germany
    Shock 24:219-25. 2005
    ..This finding may prompt future efforts in the therapy of closed soft tissue trauma to focus not only on antimediator strategies, but to add regimens targeting perfusion failure and tissue apoptosis...
  31. ncbi request reprint Activated protein C reduces tissue hypoxia, inflammation, and apoptosis in traumatized skeletal muscle during endotoxemia
    Philip Gierer
    Institute for Experimental Surgery, University of Rostock, Germany
    Crit Care Med 35:1966-71. 2007
    ..Activated protein C, a natural coagulatory inhibitor, was recently shown to reduce mortality in septic patients. We herein report on the actions of activated protein C on skeletal muscle injury in experimental endotoxemia...
  32. ncbi request reprint Current concepts review - fractures in the region of the elbow
    G Gradl
    Department for Trauma Surgery, University of Aachen, Germany
    Acta Chir Orthop Traumatol Cech 79:203-12. 2012
    ..This paper reviews the published scientific data and current opinion available to guide patient care...
  33. ncbi request reprint In vivo evidence for apoptosis, but not inflammation in the hindlimb muscle of neuropathic rats
    Georg Gradl
    Department of Trauma and Reconstructive Surgery, University of Rostock, Rostock, Germany
    Pain 112:121-30. 2004
    ..e. prompting muscle cells to undergo non-inflammatory apoptotic cell death. This finding deserves further investigation in that apoptosis may contribute to neuropathic pain conditions like CRPS...
  34. ncbi request reprint Detection of fibular torsional deformities after surgery for ankle fractures with a novel CT method
    Attila Vasarhelyi
    University of Rostock, Trauma and Reconstructive Surgery, Schillingallee 35, Rostock, D 18055, Germany
    Foot Ankle Int 27:1115-21. 2006
    ..Substantial fibular torsional deformities were detected after surgery for ankle fractures combined with a lesion of the syndesmotic complex using a novel CT analyzing method...
  35. ncbi request reprint Ischemic preconditioning prevents skeletal muscle tissue injury, but not nerve lesion upon tourniquet-induced ischemia
    Matthias Schoen
    Institute for Experimental Surgery, Department of Trauma and Reconstructive Surgery, University of Rostock, Rostock, Germany
    J Trauma 63:788-97. 2007
    ..We demonstrate that tourniquet hind limb ischemia-induced injury of the muscle benefits from IPC, whereas the peripheral nerve suffers from prolonged ischemia time and mechanical deterioration on IPC...
  36. pmc Gene expression profile and synovial microcirculation at early stages of collagen-induced arthritis
    Philip Gierer
    Department of Experimental Surgery, University of Rostock, Rostock, Germany
    Arthritis Res Ther 7:R868-76. 2005
    ..Online in vivo data on synovial tissue microcirculation, together with gene expression profiling, emphasize the potential role played by early inflammatory events in the development of arthritis...
  37. ncbi request reprint Imaging in early posttraumatic complex regional pain syndrome: a comparison of diagnostic methods
    Matthias Schürmann
    Department of Trauma and Orthopedic Surgery, Sana Klinikum Hof, University of Erlangen Nurnberg, Eppenreuther Strasse 9, 95035 Hof, Germany
    Clin J Pain 23:449-57. 2007
    ..Several diagnostic procedures are applied to facilitate an early diagnosis, although their value for diagnosing posttraumatic CRPS I is unclear...
  38. ncbi request reprint Early diagnosis in post-traumatic complex regional pain syndrome
    Matthias Schürmann
    Department of Traumatology and Orthopedic Surgery, University of Erlangen, Sana Klinikum Hof, Hof, Germany
    Orthopedics 30:450-6. 2007
    ..In questionable cases repeated examinations after short periods detect the presence of complex regional pain syndrome in orthopedic patients, particularly if symptoms are progressive or an expected improvement does not occur...