Research Topics
| Alexander GoesmannSummaryAffiliation: University of Bielefeld Country: Germany Publications
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Detail Information
Publications
PathFinder: reconstruction and dynamic visualization of metabolic pathwaysAlexander Goesmann
Center for Genome Research, Department of Genetics, Bielefeld University, 33594 Bielefeld, Germany
Bioinformatics 18:124-9. 2002..As an Relational Database Management System (RDBMS) based internet application PathFinder reads a list of EC-numbers or a given annotation in EMBL- or Genbank-format and dynamically generates pathway graphs...
Building a BRIDGE for the integration of heterogeneous data from functional genomics into a platform for systems biologyAlexander Goesmann
Center for Genome Research, Bielefeld University, D 33594 Bielefeld, Germany
J Biotechnol 106:157-67. 2003..We have implemented a Bioinformatics Resource for the Integration of heterogeneous Data from Genomic Explorations (BRIDGE) and illustrate the usability of our approach as a platform for systems biology for two sample applications...
Genetic diversity and composition of a plasmid metagenome from a wastewater treatment plantAndreas Schluter
Department of Genetics, Bielefeld University, Postfach 100131, D 33501 Bielefeld, Germany
J Biotechnol 136:65-76. 2008..EGT analysis thus proofed to be a very valuable method to explore genetic diversity and composition of the present plasmid metagenome dataset...
Taxonomic composition and gene content of a methane-producing microbial community isolated from a biogas reactorLutz Krause
Centrum für Biotechnologie CeBiTec, Universitat Bielefeld, D 33594 Bielefeld, Germany
J Biotechnol 136:91-101. 2008..Finally, the results unveiled that most of the organisms constituting the sample are still unexplored...
EMMA: a platform for consistent storage and efficient analysis of microarray dataMichael Dondrup
Center for Genome Research, Bielefeld University, D-33594 Bielefeld, Germany
J Biotechnol 106:135-46. 2003..In addition to routine data analysis algorithms, the system can be integrated with other components that contain additional data sources (e.g. genome annotation systems)...
Visualizing post genomics data-sets on customized pathway maps by ProMeTra-aeration-dependent gene expression and metabolism of Corynebacterium glutamicum as an exampleHeiko Neuweger
Computational Genomics, Center for Biotechnology, Bielefeld University, Bielefeld, Germany
BMC Syst Biol 3:82. 2009..It has become obvious that the application of web-based and user driven software tools has great potential and benefits from the use of open and standardized formats for the description of pathways...
Bioinformatics support for high-throughput proteomicsAndreas Wilke
Center for Genome Research, Bielefeld University, D 33594 Bielefeld, Germany
J Biotechnol 106:147-56. 2003..First tests showed that the automation resulted in a significant saving of time. Furthermore, the quality and interpretability of the results was improved in all cases...
EMMA 2--a MAGE-compliant system for the collaborative analysis and integration of microarray dataMichael Dondrup
Computational Genomics, Center for Biotechnology, Bielefeld University, 33594 Bielefeld, Germany
BMC Bioinformatics 10:50. 2009..Integration of genomic annotation data and other sources of external knowledge using open standards is therefore a key requirement for future integrated analysis systems...
Exact and complete short-read alignment to microbial genomes using Graphics Processing Unit programmingJochen Blom
Computational Genomics, Bielefeld University, Bielefeld, Germany
Bioinformatics 27:1351-8. 2011..Furthermore, most approaches return only one best hit for every query sequence, thus losing the potentially valuable information of alternative alignment positions with identical scores...
TACOA: taxonomic classification of environmental genomic fragments using a kernelized nearest neighbor approachNaryttza N Diaz
Center for Biotechnology CeBiTec, Bielefeld University, Bielefeld, Germany
BMC Bioinformatics 10:56. 2009..We present a novel strategy to predict the taxonomic origin of environmental genomic fragments. The proposed classifier combines the idea of the k-nearest neighbor with strategies from kernel-based learning...
Whole genome shotgun sequencing guided by bioinformatics pipelines--an optimized approach for an established techniqueOlaf Kaiser
Lehrstuhl fur Genetik, Universitat Bielefeld, D 33594 Bielefeld, Germany
J Biotechnol 106:121-33. 2003..vesicatoria 85-10. Our pipeline relies on standard tools (e.g. PHRED/PHRAP, CAP3 and Consed/Autofinish) wherever possible, supplementing them with new tools (BioMake and BACCardI) to achieve the aims described above...
The complete genome sequence of the dominant Sinorhizobium meliloti field isolate SM11 extends the S. meliloti pan-genomeSusanne Schneiker-Bekel
Center for Biotechnology CeBiTec, Bielefeld University, Institute for Genome Research and Systems Biology, Universitatsstr 27, D 33615 Bielefeld, Germany
J Biotechnol 155:20-33. 2011..Most remarkably, pSmeSM11b contains a new gene cluster predicted to be involved in polysaccharide biosynthesis. Compilation of the S. meliloti SM11 genome sequence contributes to an extension of the S. meliloti pan-genome...
Qupe--a Rich Internet Application to take a step forward in the analysis of mass spectrometry-based quantitative proteomics experimentsStefan P Albaum
Computational Genomics, Center for Biotechnology CeBiTec, Biodata Mining and Applied Neuroinformatics Group, Faculty of Technology, Bielefeld University, Bielefeld, Germany
Bioinformatics 25:3128-34. 2009....
MeltDB: a software platform for the analysis and integration of metabolomics experiment dataHeiko Neuweger
International NRW Graduate School in Bioinformatics and Genome Research, Bielefeld University, Germany
Bioinformatics 24:2726-32. 2008..Currently there exists no such system that on the one hand supports preprocessing of raw datasets but also allows to visualize and integrate the results of higher level statistical analyses within a functional genomics context...
TRUNCATULIX--a data warehouse for the legume communityKolja Henckel
Bioinformatics Resource Facility, Center for Biotechnology, Bielefeld University, Bielefeld, Germany
BMC Plant Biol 9:19. 2009..Thus, we created the data warehouse TRUNCATULIX, an integrative database of Medicago truncatula sequence and expression data...
EDGAR: a software framework for the comparative analysis of prokaryotic genomesJochen Blom
Computational Genomics, Center for Biotechnology CeBiTec, Bielefeld University, Bielefeld, Germany
BMC Bioinformatics 10:154. 2009..A main task in comparative genomics is the identification of orthologous genes in different genomes and the classification of genes as core genes or singletons...
Comparative and joint analysis of two metagenomic datasets from a biogas fermenter obtained by 454-pyrosequencingSebastian Jaenicke
Computational Genomics, Center for Biotechnology CeBiTec, Bielefeld University, Bielefeld, Germany
PLoS ONE 6:e14519. 2011....
Profiling of the metabolically active community from a production-scale biogas plant by means of high-throughput metatranscriptome sequencingMartha Zakrzewski
Computational Genomics, Center for Biotechnology CeBiTec, Bielefeld University, Bielefeld, Germany
J Biotechnol 158:248-58. 2012..In the future, key transcripts for the biogas production process will provide valuable markers for evaluation of the performance of biogas-producing microbial communities with the objective to optimize the biotechnology of this process...
Genome sequence of Wickerhamomyces anomalus DSM 6766 reveals genetic basis of biotechnologically important antimicrobial activitiesJessica Schneider
Center for Biotechnology, Bielefeld University, Bielefeld, Germany
FEMS Yeast Res 12:382-6. 2012..anomalus DSM 6766 coding for proteins participating in antimicrobial activities...
Insight into the plasmid metagenome of wastewater treatment plant bacteria showing reduced susceptibility to antimicrobial drugs analysed by the 454-pyrosequencing technologyRafael Szczepanowski
Department of Genetics, Bielefeld University, Postfach 100131, D 33501 Bielefeld, Germany
J Biotechnol 136:54-64. 2008..Plasmid metagenome sequence reads could be assembled into 605 contigs with a minimum length of 500 bases. Contigs predominantly encode plasmid survival functions and transposition enzymes...
Development of joint application strategies for two microbial gene findersAlice C McHardy
Center for Biotechnology (CeBiTec, Bielefeld University, Bielefeld, Germany
Bioinformatics 20:1622-31. 2004..The method is currently being applied for the annotation of several microbial genomes. AVAILABILITY: The methods described have been implemented within the gene prediction component of the GenDB genome annotation system...
GenDB--an open source genome annotation system for prokaryote genomesFolker Meyer
Center for Genome Research, Department of Biology, Bielefeld University, Bielefeld, Germany
Nucleic Acids Res 31:2187-95. 2003..In addition to its use as a production genome annotation system, it can be employed as a flexible framework for the large-scale evaluation of different annotation strategies. The system is open source...
The metagenome of a biogas-producing microbial community of a production-scale biogas plant fermenter analysed by the 454-pyrosequencing technologyAndreas Schluter
Lehrstuhl fur Genetik, Universitat Bielefeld, D 33594 Bielefeld, Germany
J Biotechnol 136:77-90. 2008..Metagenome sequence data from a biogas-producing microbial community residing in a fermenter of a biogas plant provide the basis for a rational approach to improve the biotechnological process of biogas production...
RAPYD--rapid annotation platform for yeast dataJessica Schneider
Computational Genomics, Institute for Bioinformatics, Center for Biotechnology, Bielefeld University, Bielefeld, Germany
J Biotechnol 155:118-26. 2011..An in-depth application example of the yeast Meyerozyma guilliermondii illustrates the functionality of RAPYD. A user-friendly web interface is available at https://rapyd.cebitec.uni-bielefeld.de...
WebCARMA: a web application for the functional and taxonomic classification of unassembled metagenomic readsWolfgang Gerlach
Faculty of Technology, Bielefeld University, Bielefeld, Germany
BMC Bioinformatics 10:430. 2009..CARMA is a new software pipeline for the characterisation of species composition and the genetic potential of microbial samples using short, unassembled reads...
Draft genome sequence of Wickerhamomyces ciferrii NRRL Y-1031 F-60-10Jessica Schneider
Institute for Genome Research and Systems Biology, Bielefeld University, Bielefeld, Germany
Eukaryot Cell 11:1582-3. 2012..This information will contribute to the metabolic engineering of this yeast to improve the yield and spectrum of acetylated sphingoid bases in biotechnological production...
CoryneCenter - an online resource for the integrated analysis of corynebacterial genome and transcriptome dataHeiko Neuweger
Computational Methods for Emerging Technologies group, Bielefeld University, Bielefeld, Germany
BMC Syst Biol 1:55. 2007..The discovery of transcriptional regulatory interactions has become a major topic in modern functional genomics...
Unraveling the Chinese hamster ovary cell line transcriptome by next-generation sequencingJennifer Becker
Centrum für Biotechnologie, Universitat Bielefeld, 33594 Bielefeld, Germany
J Biotechnol 156:227-35. 2011..The present manuscript represents a data set of assembled and annotated genes for CHO cells that can now be used for a detailed analysis of the molecular functioning of CHO cell lines...
Complete genome sequencing of Agrobacterium sp. H13-3, the former Rhizobium lupini H13-3, reveals a tripartite genome consisting of a circular and a linear chromosome and an accessory plasmid but lacking a tumor-inducing Ti-plasmidDaniel Wibberg
Institute for Genome Research and Systems Biology, CeBiTec, Bielefeld University, D 33501 Bielefeld, Germany
J Biotechnol 155:50-62. 2011..6 Mb) is only distantly related to the plasmid pAtC58 of A. tumefaciens C58 and shows a mosaic structure. A tumor-inducing Ti-plasmid is missing in the sequenced strain H13-3 indicating that it is a non-virulent isolate...
Conveyor: a workflow engine for bioinformatic analysesBurkhard Linke
Bioinformatics Resource Faciliy, Center for Biotechnology and Faculty of Technology, Bielefeld University, 33615 Bielefeld, Germany
Bioinformatics 27:903-11. 2011..The currently available workflow systems achieve this goal, but fundamentally differ in their way of executing workflows...
Phylogenetic classification of short environmental DNA fragmentsLutz Krause
Center for Biotechnology CeBiTec, Bioinformatics Resource Facility BRF, Bielefeld University, D 33594 Bielefeld, Germany
Nucleic Acids Res 36:2230-9. 2008..The algorithm was applied in a comparative study of three aquatic microbial samples obtained by 454 pyrosequencing. Profound differences in the taxonomic composition of these samples could be clearly revealed...
The ubiquitous plasmid pXap41 in the invasive phytopathogen Xanthomonas arboricola pv. pruni: complete sequence and comparative genomic analysisJoël F Pothier
Agroscope Changins Wädenswil ACW, Plant Protection Division, Wädenswil, SwitzerlandCeBiTec, Bielefeld University, Bielefeld, Germany
FEMS Microbiol Lett 323:52-60. 2011..This plasmid was not detected in any other X. arboricola pathovars (n=12), indicating the potential for the application of the pXap41 PCR method as a pathovar-level detection and identification tool...
Comparative Pathway Analyzer--a web server for comparative analysis, clustering and visualization of metabolic networks in multiple organismsSebastian Oehm
Center for Biotechnology CeBiTec, Bielefeld University, D 33594 Bielefeld, Germany
Nucleic Acids Res 36:W433-7. 2008..Additionally, users can upload their own annotation data. This website is free and open to all users and there is no login requirement. It is available at https://www.cebitec.uni-bielefeld.de/groups/brf/software/cpa/index.html...
Development of bioinformatic tools to support EST-sequencing, in silico- and microarray-based transcriptome profiling in mycorrhizal symbiosesHelge Küster
Institute for Genome Research, Center for Biotechnology CeBiTec, Universitat Bielefeld, Universitatsstrasse 25, 33594 Bielefeld, Germany
Phytochemistry 68:19-32. 2007..Together, the EST- and transcriptome databases can be mined to identify candidate genes for targeted functional studies...
Trace2PS and FSA2PS: two software toolkits for converting trace and fsa files to PostScript formatJustina Krawczyk
Computational Genomics, Center for Biotechnology CeBiTec, 33594 Bielefeld, Germany
Source Code Biol Med 4:4. 2009..To allow for a quick conversion of the proprietary data format into a commonly used one, toolkits are required that reach this aim and can be easily integrated into workflow systems...
The complete genome sequence of Corynebacterium pseudotuberculosis FRC41 isolated from a 12-year-old girl with necrotizing lymphadenitis reveals insights into gene-regulatory networks contributing to virulenceEva Trost
Institut für Genomforschung und Systembiologie, Centrum für Biotechnologie, Universitat Bielefeld, Bielefeld, Germany
BMC Genomics 11:728. 2010..To detect potential virulence factors and corresponding gene-regulatory networks in this human isolate, the genome sequence of C. pseudotuberculosis FCR41 was determined by pyrosequencing and functionally annotated...
Complete genome sequence and analysis of the multiresistant nosocomial pathogen Corynebacterium jeikeium K411, a lipid-requiring bacterium of the human skin floraAndreas Tauch
Institut für Genomforschung, Centrum für Biotechnologie, Universitat Bielefeld, Universitatsstrasse 25, D 33615 Bielefeld, Germany
J Bacteriol 187:4671-82. 2005..The predicted virulence factors of C. jeikeium K411 are apparently involved in ensuring the availability of exogenous fatty acids by damaging the host tissue...
Ultrafast pyrosequencing of Corynebacterium kroppenstedtii DSM44385 revealed insights into the physiology of a lipophilic corynebacterium that lacks mycolic acidsAndreas Tauch
Institut für Genomforschung und Systembiologie, Centrum für Biotechnologie, Universitat Bielefeld, Universitatsstrasse 25, D 33615 Bielefeld, Germany
J Biotechnol 136:22-30. 2008..A complete beta-oxidation pathway involved in the degradation of fatty acids is present in the genome. Evaluation of the genomic data indicated that lipophilism is the dominant feature involved in pathogenicity of C. kroppenstedtii...
The Sequence Analysis and Management System -- SAMS-2.0: data management and sequence analysis adapted to changing requirements from traditional sanger sequencing to ultrafast sequencing technologiesThomas Bekel
Computational Genomics, Center for Biotechnology CeBiTec, Universitat Bielefeld, Bielefeld, Germany
J Biotechnol 140:3-12. 2009..The system has been implemented to cope with several thousands of sequences, efficiently processing them and storing the results for further analysis. With the project setup, SAMS automatically recognizes the data type...
The lifestyle of Corynebacterium urealyticum derived from its complete genome sequence established by pyrosequencingAndreas Tauch
Institut für Genomforschung und Systembiologie, Centrum für Biotechnologie, Universitat Bielefeld, Universitatsstrasse 25, D 33615 Bielefeld, Germany
J Biotechnol 136:11-21. 2008..The complete genome sequence of C. urealyticum revealed a detailed picture of the lifestyle of this opportunistic human pathogen...
The complete Corynebacterium glutamicum ATCC 13032 genome sequence and its impact on the production of L-aspartate-derived amino acids and vitaminsJorn Kalinowski
Institut für Genomforschung, Universitat Bielefeld, Universitatsstrasse 25, D 33615 Bielefeld, Germany
J Biotechnol 104:5-25. 2003..As an example for biotechnological application the complete genome sequence was used to reconstruct the metabolic flow of carbon into a number of industrially important products derived from the amino acid L-aspartate...
An evaluation framework for statistical tests on microarray dataMichael Dondrup
Center for Biotechnology, Bielefeld University, Bielefeld, Germany
J Biotechnol 140:18-26. 2009..Specifically, we report that for four replicates all methods reach a high to very high correlation with our reference standard...
A guide through the computational analysis of isotope-labeled mass spectrometry-based quantitative proteomics data: an application studyStefan P Albaum
Computational Genomics, Center for Biotechnology CeBiTec, Bielefeld University, Germany
Proteome Sci 9:30. 2011..abstract:..
Lipopolysaccharide biosynthesis genes discriminate between Rubus- and Spiraeoideae-infective genotypes of Erwinia amylovoraFabio Rezzonico
Agroscope Changins Wädenswil ACW, Plant Protection Division, Swiss National Competence Centre for Fire Blight, CH 8820 Wadenswil, Switzerland
Mol Plant Pathol 13:975-84. 2012..The LPS biosynthesis gene cluster may thus be used as a molecular marker to distinguish between Rubus- and Spiraeoideae-infecting strains of E. amylovora using primers designed in this study...
Construction and evaluation of a whole genome microarray of Chlamydomonas reinhardtiiJörg Toepel
Algae Biotechnology and Bioenergy, Dept, of Biology, Center for Biotechnology CeBiTec, Bielefeld University, 33615 Bielefeld, Germany
BMC Genomics 12:579. 2011..Based on the completed annotation of Chlamydomonas reinhardtii a new microarray on an Agilent platform was designed using an extended JGI 3.1 genome data set which included 15000 transcript models...
MediPlEx - a tool to combine in silico & experimental gene expression profiles of the model legume Medicago truncatulaKolja Henckel
Bioinformatics of Signaling Networks, Center for Biotechnology, Bielefeld University, Germany
BMC Res Notes 3:262. 2010..Under these circumstances, the challenge arises to combine results derived from the different expression profiling strategies, with the goal to uncover novel information on the basis of the integrated datasets...
Complete genome sequence of the myxobacterium Sorangium cellulosumSusanne Schneiker
Department of Genetics, Bielefeld University, PO Box 100131, D 33501 Bielefeld, Germany
Nat Biotechnol 25:1281-9. 2007..Seventeen secondary metabolite loci are encoded in the genome, as well as many enzymes with potential utility in industry...
The genome sequence of Mycoplasma mycoides subsp. mycoides SC type strain PG1T, the causative agent of contagious bovine pleuropneumonia (CBPP)Joakim Westberg
Department of Biotechnology, Royal Institute of Technology (KTH, SE-106 91 Stockholm, Sweden
Genome Res 14:221-7. 2004....
Whole-genome comparison of disease and carriage strains provides insights into virulence evolution in Neisseria meningitidisChristoph Schoen
Institute for Hygiene and Microbiology, University of Wurzburg, Josef Schneider Strasse 2, 97080 Wurzburg, Germany
Proc Natl Acad Sci U S A 105:3473-8. 2008..meningitidis has emerged as an unencapsulated human commensal from a common ancestor with Neisseria gonorrhoeae and Neisseria lactamica and consecutively acquired the genes responsible for capsule synthesis via horizontal gene transfer...
Antibiotic multiresistance plasmid pRSB101 isolated from a wastewater treatment plant is related to plasmids residing in phytopathogenic bacteria and carries eight different resistance determinants including a multidrug transport systemRafael Szczepanowski
Fakultat fur Biologie, Lehrstuhl fur Genetik, Universitat Bielefeld, Postfach 100131, D 33501 Bielefeld, Germany
Microbiology 150:3613-30. 2004....
A predator unmasked: life cycle of Bdellovibrio bacteriovorus from a genomic perspectiveSnjezana Rendulic
Max-Planck-Institute for Developmental Biology, , Germany
Science 303:689-92. 2004..A plethora of paralogous gene families coding for enzymes, such as hydrolases and transporters, are used throughout the life cycle of B. bacteriovorus for prey entry, prey killing, and the uptake of complex molecules...
BACCardI--a tool for the validation of genomic assemblies, assisting genome finishing and intergenome comparisonDaniela Bartels
, Center for Biotechnology (CeBiTec) D-33594 Bielefeld, Germany
Bioinformatics 21:853-9. 2005..The time-consuming task of building physical maps can be circumvented by virtual clone maps derived from read pair information of large insert libraries...
The subsystems approach to genome annotation and its use in the project to annotate 1000 genomesRoss Overbeek
Fellowship for Interpretation of Genomes, 15W155 81st Street, Burr Ridge, IL 60527, USA
Nucleic Acids Res 33:5691-702. 2005..The initial release of data includes 180 177 distinct proteins with 2133 distinct functional roles. This data comes from 173 subsystems and 383 different organisms...
Complete genome sequence of the prototype lactic acid bacterium Lactococcus lactis subsp. cremoris MG1363Udo Wegmann
Department of Molecular Genetics, Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, Kerklaan 30, 9751 NN Haren, The Netherlands
J Bacteriol 189:3256-70. 2007..The availability of the L. lactis MG1363 genome sequence will reinforce its status as the prototype among lactic acid bacteria through facilitation of further applied and fundamental research...
The multiple antibiotic resistance IncP-1 plasmid pKJK5 isolated from a soil environment is phylogenetically divergent from members of the previously established alpha, beta and delta sub-groupsMartin Iain Bahl
Department of Microbiology, University of Copenhagen, Sølvgade 83H, 1307 Copenhagen K, Denmark
Plasmid 58:31-43. 2007....
The missing link: Bordetella petrii is endowed with both the metabolic versatility of environmental bacteria and virulence traits of pathogenic BordetellaeRoy Gross
Chair of Microbiology, Biocenter, University of Wurzburg, Am Hubland, D 97074 Wurzburg, Germany
BMC Genomics 9:449. 2008..Recently, clinical isolates associated with bone degenerative disease or cystic fibrosis have also been described...
Comparative genomic hybridisation and ultrafast pyrosequencing revealed remarkable differences between the Sinorhizobium meliloti genomes of the model strain Rm1021 and the field isolate SM11Michael Stiens
Fakultat fur Biologie, Lehrstuhl fur Genetik, Universitat Bielefeld, Postfach 100131, D 33501 Bielefeld, Germany
J Biotechnol 136:31-7. 2008..iii) S. meliloti SM11 megaplasmid pSymB lacks a complete cell surface carbohydrate synthesis gene cluster. (iv) Several genes that are absent in the SM11 genome could be assigned to insertion sequences and transposons...
Complete genome of the mutualistic, N2-fixing grass endophyte Azoarcus sp. strain BH72Andrea Krause
Laboratory of General Microbiology, University of Bremen, PO Box 330440, D-28334 Bremen, Germany
Nat Biotechnol 24:1385-91. 2006..The genome contains remarkably few mobile elements, indicating a low rate of recent gene transfer that is presumably due to adaptation to a stable, low-stress microenvironment...
The genome sequence of the tomato-pathogenic actinomycete Clavibacter michiganensis subsp. michiganensis NCPPB382 reveals a large island involved in pathogenicityKarl Heinz Gartemann
Lehrstuhl für Gentechnologie Mikrobiologie, Universitat Bielefeld, D 33501 Bielefeld, Germany
J Bacteriol 190:2138-49. 2008..michiganensis subsp. michiganensis dependent on reduced sulfur compounds for growth, is probably the reason for the poor survival of C. michiganensis subsp. michiganensis in soil...
Whole-genome sequence of Listeria welshimeri reveals common steps in genome reduction with Listeria innocua as compared to Listeria monocytogenesTorsten Hain
Institute for Medical Microbiology, Justus-Liebig-University, Frankfurter Strasse 107, D-35392 Giessen, Germany
J Bacteriol 188:7405-15. 2006..The species L. welshimeri appears to have been derived from early evolutionary events and an ancestor more compact than L. monocytogenes that led to the emergence of nonpathogenic Listeria spp...
Genome sequence of the ubiquitous hydrocarbon-degrading marine bacterium Alcanivorax borkumensisSusanne Schneiker
, , , D-33594 Bielefeld, Germany
Nat Biotechnol 24:997-1004. 2006..borkumensis SK2 with a competitive edge in oil-polluted environments. This genome sequence provides the basis for the future design of strategies to mitigate the ecological damage caused by oil spills...
Insights into genome plasticity and pathogenicity of the plant pathogenic bacterium Xanthomonas campestris pv. vesicatoria revealed by the complete genome sequenceFrank Thieme
, , Weinbergweg 10, D-06120 Halle (Saale, Germany
J Bacteriol 187:7254-66. 2005..Comparisons with other completely sequenced plant pathogens predicted six novel type III effector proteins and several other virulence factors, including adhesins, cell wall-degrading enzymes, and extracellular polysaccharides...
Genomic sequence of chorioallantois vaccinia virus Ankara, the ancestor of modified vaccinia virus AnkaraChristine Meisinger Henschel
Bavarian Nordic GmbH, Fraunhoferstrasse 13, D 82152 Martinsried, Germany
J Gen Virol 88:3249-59. 2007..Thus, detailed knowledge of the CVA genomic sequence is a prerequisite to further dissect the genetic basis of the MVA host range phenotype as well as the particular immunological properties of MVA...
The genome of Xanthomonas campestris pv. campestris B100 and its use for the reconstruction of metabolic pathways involved in xanthan biosynthesisFrank Jörg Vorhölter
Universitat Bielefeld, Biologie VI Genetik, Universitatsstr 25, D 33615 Bielefeld, Germany
J Biotechnol 134:33-45. 2008..The updated genome annotation data allowed reconsidering and refining the mechanistic model for xanthan biosynthesis...
