Research Topics
| A GingelmaierSummaryAffiliation: University of Munich Country: Germany Publications
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Detail Information
Publications
The mitochondria-independent cytotoxic effect of nelfinavir on leukemia cells can be enhanced by sorafenib-mediated mcl-1 downregulation and mitochondrial membrane destabilizationAnsgar Brüning
Ludwig Maximilians University Munich, Department of Obstetrics Gynaecology, Molecular Biology Laboratory, Munich, Germany
Mol Cancer 9:19. 2010..It has recently emerged that nelfinavir could represent a prospective new anti-cancer drug, prompting us to test the effect of nelfinavir on leukemia cells...
Expression of HPV, steroid receptors (ERalpha, ERbeta, PR-A and PR-B) and inhibin/activin subunits (alpha, betaA and betaB) in adenosquamous endometrial carcinomaAndrea Gingelmaier
First Department of Obstetrics and Gynecology, Ludwig Maximilians University, Munich, Germany
Anticancer Res 27:2011-7. 2007..The aim of the study was to determine possible pathogenetic factors and molecules which may be used as tumor markers of adenosquamous endometrial carcinoma...
High recurrence rate of cervical dysplasia and persistence of HPV infection in HIV-1-infected womenAndrea Gingelmaier
First Department of Obstetrics and Gynecology, Ludwig Maximilians University, Munich, Germany
Anticancer Res 27:1795-8. 2007..A) evaluation of the recurrence of cervical dysplasia after surgical treatment and of the rate of HPV persistence of HIV-infected women and b) the influence of antiretroviral therapy on the recurrence...
Mitochondrial toxicity in HIV type-1-exposed pregnancies in the era of highly active antiretroviral therapyAndrea Gingelmaier
Department of Obstetrics and Gynaecology, Ludwig Maximilians University of Munich, Munich, Germany
Antivir Ther 14:331-8. 2009..The aim of this study was to determine the effects of HIV type-1 (HIV-1) infection and antiretroviral therapy (ART) on placental mitochondria...
Consultations of HIV-infected women who wish to become pregnantAndrea Gingelmaier
Department of Obstetrics and Gynecology, Ludwig Maximilians University of Munich, Maistrasse 11, 80337 Munich, Germany
Arch Gynecol Obstet 283:893-8. 2011..The aim of this study was to determine the impact and outcome of consultations of HIV-infected women if a pregnancy is planned...
Placental transfer and pharmacokinetics of lopinavir and other protease inhibitors in combination with nevirapine at deliveryAndrea Gingelmaier
1st Department of Obstetrics and Gynecology, Ludwig Maximilians University of Munich, Maistrasse 11, 80337 Munich, Germany
AIDS 20:1737-43. 2006..Antiretroviral combination therapies, including nevirapine (NVP) and protease inhibitors (PI), are increasingly used in the treatment and for the prophylaxis of vertical HIV-1 transmission in HIV-1 infected pregnant women...
[Inflammatory diseases of the vulva and vagina]A Gingelmaier
Frauenklinik, , Maistrasse 11, 80337 Munich
Hautarzt 57:155-69, quiz 170. 2006
[Genital mycoses]Andrea Gingelmaier
Med Monatsschr Pharm 28:309-12; quiz 313. 2005
Protease inhibitor-based antiretroviral prophylaxis during pregnancy and the development of drug resistanceAndrea Gingelmaier
Department of Obstetrics and Gynecology, Medizinische Poliklinik, University Hospital of Munich, Downtown Campus, Munich, Germany
Clin Infect Dis 50:890-4. 2010....
Anal cytology as a screening tool for early detection of anal dysplasia in HIV-infected womenAndrea Gingelmaier
Department of Obstetrics and Gynecology, Downtown Campus, Ludwig Maximilians University, Munich, Germany
Anticancer Res 30:1719-23. 2010....
Nelfinavir induces mitochondria protection by ERK1/2-mediated mcl-1 stabilization that can be overcome by sorafenibAnsgar Brüning
Department of Obstetrics Gynaecology, Molecular Biology Laboratory, Ludwig Maximilians University Munich, Munich, Germany
Invest New Drugs 28:535-42. 2010..Thus, a combination of these two investigational anti-cancer drugs could be of interest especially because of their unique mechanism of apoptosis induction even in otherwise chemo-resistant human cancer cells...
Interleukin-6, interleukin-10 and interleukin-12 in vaginal fluid from women with bacterial vaginosisT Weissenbacher
1st Department of Obstetrics and Gynecology, Ludwig Maximilians University, Maistrasse 11, Munich, Germany
Arch Gynecol Obstet 281:77-80. 2010..We investigated the influence of BV on the vaginal concentration of the pro-inflammatory cytokine interleukin (IL)-12, the pleiotropic cytokine IL-6 and the anti-inflammatory cytokine IL-10 in non-pregnant women...
Evaluation of pelvic floor muscle strength using four different techniquesU M Peschers
I Frauenklinik, Ludwig Maximilians Universitaet, Munich, Germany
Int Urogynecol J Pelvic Floor Dysfunct 12:27-30. 2001..It was concluded that EMG and pressure perineometry do not selectively depict pelvic floor muscle activity...
[Chlamydia trachomatis infections--a time for action?]I Mylonas
Klinik fur Gynakologie und Geburtshilfe, Klinikum Innenstadt, Ludwig Maximilians Universitat Munchen, Germany
Dtsch Med Wochenschr 132:1170-6. 2007..This issue is not only of extreme importance in health policy, but has also a major impact in family policy, especially in view of the declining birth rates and the demographic changes...
New prospects for nelfinavir in non-HIV-related diseasesAnsgar Brüning
Ludwig Maximilians University Munich, Department of Obstetrics Gynecology, Campus Innenstadt, Munich, Germany
Curr Mol Pharmacol 3:91-7. 2010..Several cancer-related clinical studies on nelfinavir as a single agent or in combination therapies have been launched and are expected to add to the usefulness of this versatile drug for cancer treatment strategies or other purposes...
Nelfinavir induces TRAIL receptor upregulation in ovarian cancer cellsAnsgar Brüning
University Hospital Munich, Department of Obstetrics Gynecology, Maistrasse 11, 80337 Munich, Germany
Biochem Biophys Res Commun 377:1309-14. 2008....
Development and characterisation of an antibody for the immunohistochemical detection of inhibin/activin betaE (betaE) in normal human ovarian and placental tissueIoannis Mylonas
1st Department of Obstetrics and Gynaecology, Ludwig Maximilians University Munich, Maistrasse 11, 80337 Munich, Germany
Acta Histochem 111:366-71. 2009..However, the function of this subunit in humans remains still unclear and warrants further research...
Inhibin-alpha subunit is an independent prognostic parameter in human endometrial carcinomas: analysis of inhibin/activin-alpha, -betaA and -betaB subunits in 302 casesIoannis Mylonas
1st Department of Obstetrics and Gynaecology, Ludwig Maximilians University Munich, Maistrasse 11, 80337 Munich, Bavaria, Germany
Eur J Cancer 45:1304-14. 2009..Therefore, inhibin-alpha immunostaining might be used as a simple and efficient marker to identify high-risk patients leading to the selection of patients for an aggressive adjuvant therapy...
The immunohistochemical expression of the inhibin/activin subunits is up-regulated by interferon-beta1a in Ishikawa cell lineAnna Hoeing
Ludwig Maximilians University Munich, First Department of Obstetrics and Gynecology, Maistrasse 11, 80337 Munich, Germany
Anticancer Res 27:2005-10. 2007..Therefore, the aim of this study was to determine expression changes of inhibin/activin subunits in the endometrial Ishikawa carcinoma cell line after stimulation with interferon-beta1a...
Relationship between clinical diagnosis of recurrent vulvovaginal candidiasis and detection of Candida species by culture and polymerase chain reactionT Weissenbacher
First Department of Obstetrics and Gynecology, Klinikum Innenstadt, Ludwig Maximilians University, Maistrasse 11, Munich, Germany
Arch Gynecol Obstet 279:125-9. 2009..In 5% of these women, infection is recurring. Aim of the study was to determine the sensitivity of detecting Candida species by culture and polymerase chain reaction (PCR) in women with a clinical diagnosis of RVVC...
Expression of the inhibin/activin subunits (-alpha, -betaA and -betaB) in normal and carcinogenic endometrial tissue: possible immunohistochemical differentiation markersSilvia Worbs
1st Department of Obstetrics and Gynecology, Ludwig Maximilians University Munich, Maistrasse 11, 80337 Munich, Germany
Oncol Rep 17:97-104. 2007..However, the utilization of these subunits as specific tumor markers still remains unclear...
Immunohistochemical labeling of the inhibin/activin betaC subunit in normal human placental tissue and chorionic carcinoma cell linesTobias Weissenbacher
First Department of Obstetrics and Gynecology, Ludwig Maximilians University Munich, Munich, Germany
J Histochem Cytochem 58:751-7. 2010..Additionally, JEG and BeWo express betaC and, therefore, can be used as a cell culture model for further functional analysis of this subunit in the human placenta...
Prognostic significance of oestrogen receptor alpha (ERalpha) and beta (ERbeta), progesterone receptor A (PR-A) and B (PR-B) in endometrial carcinomasNaim Shabani
1st Department of Obstetrics and Gynaecology, Ludwig Maximilians University Munich, Maistrasse 11, 80337 Munich, Germany
Eur J Cancer 43:2434-44. 2007..Therefore, the PR-B immunostaining might be used as an easy, simple and highly efficient marker to identify high-risk patients and may aid in the selection of patients for a more aggressive adjuvant therapy...
The metastasis-associated genes MTA1 and MTA3 are abundantly expressed in human placenta and chorionic carcinoma cellsAnsgar Brüning
1st Department of Obstetrics and Gynaecology, Ludwig Maximilians University Munich, Maistrasse 11, 80337 Munich, Germany
Histochem Cell Biol 132:33-8. 2009....
Relationship between recurrent vulvovaginal candidosis and immune mediators in vaginal fluidTobias M Weissenbacher
Department of Obstetrics and Gynaecology, Ludwig Maximilians University, Munich, Germany
Eur J Obstet Gynecol Reprod Biol 144:59-63. 2009....
Congenital cytomegalovirus infection in pregnancy: a case report of fetal death in a CMV-infected womanBernd P Kost
First Department of Obstetrics and Gynaecology, Ludwig Maximilians University Munich, Maistrasse 11, 80337, Munich, Germany
Arch Gynecol Obstet 276:265-8. 2007..15-2.0% in developed countries. However, controversial data concerning intrauterine fetal death caused by CMV infection exist...
German-Austrian recommendations for HIV-therapy in pregnancy--common declaration of The German AIDS-society (DAIG), The Austrian AIDS-society (OEAG) as well as The Robert-Koch Institute Berlin (RKI), The German Association of Physicians specialized in HIVBernd Buchholz
Deutsche AIDS Gesellschaft, Department of Dermatology, Ruhr University Bochum, St Josef Hospital, Gudrunstr 56, D 44791 Bochum, Germany
Eur J Med Res 7:417-33. 2002..Also the procedures for different scenarios and risk constellations in pregnancy have been specified. With these current guidelines in Germany and Austria the low rate of vertical HIV-transmission should be further maintained...
German-Austrian recommendations for HIV-therapy in pregnancy: update May 2003Bernd Buchholz
Pediatric Clinic, Mannheim University, Mannheim, Germany
Eur J Med Res 9:287-303. 2004..With these current guidelines in Germany and Austria the low rate of vertical HIV-transmission should be further maintained or even further lowered...
Imiquimod leads to a decrease of human papillomavirus DNA and to a sustained clearance of anal intraepithelial neoplasia in HIV-infected menAlexander Kreuter
1Department of Dermatology, Ruhr University Bochum, Bochum, Germany
J Invest Dermatol 128:2078-83. 2008..However, new AIN lesions associated with previously undetected HPV types frequently occur in untreated areas...
