Evangelos Giannitsis

Summary

Affiliation: University of Heidelberg
Country: Germany

Publications

  1. ncbi 99th percentile and analytical imprecision of troponin and creatine kinase-MB mass assays: an objective platform for comparison of assay performance
    Evangelos Giannitsis
    Clin Chem 49:1248-9. 2003
  2. ncbi Multicentre evaluation of a new point-of-care test for the determination of CK-MB in whole blood
    Evangelos Giannitsis
    Abteilung fur Kardiologie, Angiologie und Pulmonologie, Universitatsklinikum Heidelberg, Heidelberg, Germany
    Clin Chem Lab Med 46:630-8. 2008
  3. ncbi Cardiac magnetic resonance imaging study for quantification of infarct size comparing directly serial versus single time-point measurements of cardiac troponin T
    Evangelos Giannitsis
    Abteilung Innere Medizin III, Medizinische Klinik, Universitatsklinikum Heidelberg, Heidelberg, Germany
    J Am Coll Cardiol 51:307-14. 2008
  4. ncbi Ability of DNase I activity to detect myocardial ischaemia in vasospastic angina--a view through a monocle?
    Evangelos Giannitsis
    Eur Heart J 28:2955-6. 2007
  5. ncbi Multimarker strategy in acute coronary syndrome--pro-multimarker
    Evangelos Giannitsis
    Abteilung Innere Medizin III, Medizinische Klinik, , 69120 Heidelberg, Germany
    Acute Card Care 9:6-9. 2007
  6. ncbi Pros and cons of high-sensitivity assays for cardiac troponin
    Evangelos Giannitsis
    Department of Internal Medicine III, Cardiology, University Hospital Heidelberg, Im Neuenheimer Feld 410, 69120 Heidelberg, Germany
    Nat Rev Cardiol 9:616-8. 2012
  7. ncbi Antiplatelet therapy - ticagrelor
    E Giannitsis
    Department of Internal Medicine III, Cardiology, University Hospital Heidelberg, Germany
    Hamostaseologie 32:177-85. 2012
  8. ncbi High-sensitivity cardiac troponin T for early prediction of evolving non-ST-segment elevation myocardial infarction in patients with suspected acute coronary syndrome and negative troponin results on admission
    Evangelos Giannitsis
    Medizinische Klinik, Abteilung für Innere Medizin III, Universitatsklinikum Heidelberg, Heidelberg, Germany
    Clin Chem 56:642-50. 2010
  9. ncbi Analytical validation of a high-sensitivity cardiac troponin T assay
    Evangelos Giannitsis
    Medizinische Klinik, Abteilung für Innere Medizin III, Universitatsklinikum Heidelberg, Germany
    Clin Chem 56:254-61. 2010
  10. ncbi Strain-encoded CMR for the detection of inducible ischemia during intermediate stress
    Grigorios Korosoglou
    University of Heidelberg, Department of Cardiology, Heidelberg, Germany
    JACC Cardiovasc Imaging 3:361-71. 2010

Detail Information

Publications101 found, 100 shown here

  1. ncbi 99th percentile and analytical imprecision of troponin and creatine kinase-MB mass assays: an objective platform for comparison of assay performance
    Evangelos Giannitsis
    Clin Chem 49:1248-9. 2003
  2. ncbi Multicentre evaluation of a new point-of-care test for the determination of CK-MB in whole blood
    Evangelos Giannitsis
    Abteilung fur Kardiologie, Angiologie und Pulmonologie, Universitatsklinikum Heidelberg, Heidelberg, Germany
    Clin Chem Lab Med 46:630-8. 2008
    ..The point-of-care (POC) test Roche CARDIAC CK-MB is a new assay which has been developed for the existing Roche Cardiac reader system...
  3. ncbi Cardiac magnetic resonance imaging study for quantification of infarct size comparing directly serial versus single time-point measurements of cardiac troponin T
    Evangelos Giannitsis
    Abteilung Innere Medizin III, Medizinische Klinik, Universitatsklinikum Heidelberg, Heidelberg, Germany
    J Am Coll Cardiol 51:307-14. 2008
    ..We compared single-point cardiac troponin T (cTnT) measurements with parameters from serial sampling during 96 h after acute myocardial infarction with magnetic resonance imaging measured infarct mass...
  4. ncbi Ability of DNase I activity to detect myocardial ischaemia in vasospastic angina--a view through a monocle?
    Evangelos Giannitsis
    Eur Heart J 28:2955-6. 2007
  5. ncbi Multimarker strategy in acute coronary syndrome--pro-multimarker
    Evangelos Giannitsis
    Abteilung Innere Medizin III, Medizinische Klinik, , 69120 Heidelberg, Germany
    Acute Card Care 9:6-9. 2007
  6. ncbi Pros and cons of high-sensitivity assays for cardiac troponin
    Evangelos Giannitsis
    Department of Internal Medicine III, Cardiology, University Hospital Heidelberg, Im Neuenheimer Feld 410, 69120 Heidelberg, Germany
    Nat Rev Cardiol 9:616-8. 2012
    ..Whether faster rule-out algorithms can discriminate between MI and other conditions that elevate the troponin level, or be safely implemented across the whole spectrum of patient risk, is unclear...
  7. ncbi Antiplatelet therapy - ticagrelor
    E Giannitsis
    Department of Internal Medicine III, Cardiology, University Hospital Heidelberg, Germany
    Hamostaseologie 32:177-85. 2012
    ..The new ESC guidelines on the management of ACS without ST segment elevation recommend the use of clopidogrel only when a new antiplatelet drug, e.g. ticagrelor or prasugrel is not available or contraindicated...
  8. ncbi High-sensitivity cardiac troponin T for early prediction of evolving non-ST-segment elevation myocardial infarction in patients with suspected acute coronary syndrome and negative troponin results on admission
    Evangelos Giannitsis
    Medizinische Klinik, Abteilung für Innere Medizin III, Universitatsklinikum Heidelberg, Heidelberg, Germany
    Clin Chem 56:642-50. 2010
    ..We sought to determine the diagnostic performance of the new high-sensitivity cardiac troponin T (hs-cTnT) assay for early detection of non-ST-segment myocardial infarction (NSTEMI) in patients with acute coronary syndrome...
  9. ncbi Analytical validation of a high-sensitivity cardiac troponin T assay
    Evangelos Giannitsis
    Medizinische Klinik, Abteilung für Innere Medizin III, Universitatsklinikum Heidelberg, Germany
    Clin Chem 56:254-61. 2010
    ..We report the development of a novel high-sensitivity cardiac troponin T (hs-cTnT) assay, a modification of the Roche fourth-generation cTnT assay, and validation of the analytical performance of this assay...
  10. ncbi Strain-encoded CMR for the detection of inducible ischemia during intermediate stress
    Grigorios Korosoglou
    University of Heidelberg, Department of Cardiology, Heidelberg, Germany
    JACC Cardiovasc Imaging 3:361-71. 2010
    ..This study sought to evaluate the diagnostic accuracy of strain-encoded cardiac magnetic resonance (SENC) for the detection of inducible ischemia during intermediate stress...
  11. ncbi Staged cardiovascular magnetic resonance for differential diagnosis of troponin T positive patients with low likelihood for acute coronary syndrome
    Henning Steen
    Abteilung Innere Medizin III, Medizinische Klinik, Universitatsklinikum Heidelberg, Heidelberg, Germany
    J Cardiovasc Magn Reson 12:51. 2010
    ....
  12. ncbi Early assessment of infarct size and prediction of functional recovery by quantitative myocardial blush grade in patients with acute coronary syndromes treated according to current guidelines
    Nina Riedle
    Department of Cardiology, University of Heidelberg, Heidelberg, Germany
    Catheter Cardiovasc Interv 76:502-10. 2010
    ....
  13. ncbi Predicting microvascular obstruction with cardiac troponin T after acute myocardial infarction: a correlative study with contrast-enhanced magnetic resonance imaging
    Mirja Neizel
    Medical Clinic III, University Hospital Heidelberg, Heidelberg, 69120, Germany
    Clin Res Cardiol 98:555-62. 2009
    ..The aim of this study was to evaluate whether a single cardiac troponin T-value (cTnT) was able to predict the presence of MVO and whether cTnT is an independent predictor of MVO as compared to usual risk factors...
  14. ncbi Clinical feasibility study for detection of myocardial oedema by a cine SSFP sequence in comparison to a conventional T2-weighted sequence
    Henning Steen
    Department of Cardiology, University Hospital Heidelberg, Im Neuenheimer Feld 410, 69120, Heidelberg, Germany
    Clin Res Cardiol 101:125-31. 2012
    ..We therefore sought to prospectively evaluate SSFP cine-imaging to detect myocardial oedema and differentiate AMI from CMI...
  15. ncbi Relative role of NT-pro BNP and cardiac troponin T at 96 hours for estimation of infarct size and left ventricular function after acute myocardial infarction
    Henning Steen
    Abteilung Innere Medizin III, Medizinische Klinik, Universitatsklinikum Heidelberg, Heidelberg, Germany
    J Cardiovasc Magn Reson 9:749-58. 2007
    ..The aim of the present study was to correlate infarct size and left ventricular function determined by cine and late gadolinium enhanced CMR with plasma levels of TNT and NT-pro BNP levels after AMI...
  16. ncbi Longitudinal left ventricular function for prediction of survival in systemic light-chain amyloidosis: incremental value compared with clinical and biochemical markers
    Sebastian J Buss
    Department of Cardiology, University of Heidelberg, Heidelberg, Germany
    J Am Coll Cardiol 60:1067-76. 2012
    ..The aim of the study was to determine whether longitudinal left ventricular (LV) function provides prognostic information in a large cohort of patients with systemic light-chain (AL) amyloidosis...
  17. ncbi Impact of systolic and diastolic deformation indexes assessed by strain-encoded imaging to predict persistent severe myocardial dysfunction in patients after acute myocardial infarction at follow-up
    Mirja Neizel
    Department of Cardiology, University Hospital Heidelberg, Heidelberg, Germany
    J Am Coll Cardiol 56:1056-62. 2010
    ....
  18. ncbi Prediction of coronary artery disease by a systemic atherosclerosis score index derived from whole-body MR angiography
    Stephanie Lehrke
    Abteilung Innere Medizin III, Medizinische Klinik, Universitatsklinikum Heidelberg, Heidelberg, Germany
    J Cardiovasc Magn Reson 11:36. 2009
    ....
  19. ncbi Serum levels of NT-proBNP as surrogate for cardiac amyloid burden: new evidence from gadolinium-enhanced cardiac magnetic resonance imaging in patients with amyloidosis
    Stephanie Lehrke
    Department of Medicine III, Division of Cardiology, University Hospital Heidelberg, Heidelberg, Germany
    Amyloid 16:187-95. 2009
    ..We aimed to use contrast enhanced cardiac magnetic resonance imaging (CMR) to identify functional and structural alterations related to levels of NT-proBNP better to understand the mechanisms of its release in cardiac amyloidosis...
  20. ncbi Strain-encoded (SENC) magnetic resonance imaging to evaluate regional heterogeneity of myocardial strain in healthy volunteers: Comparison with conventional tagging
    Mirja Neizel
    Department of Cardiology, University Hospital Heidelberg, Heidelberg, Germany
    J Magn Reson Imaging 29:99-105. 2009
    ..To evaluate the ability of strain-encoded (SENC) magnetic resonance imaging (MRI) for regional systolic and diastolic strain analysis of the myocardium in healthy volunteers...
  21. ncbi Use of cardiovascular magnetic resonance for risk stratification in chronic heart failure: prognostic value of late gadolinium enhancement in patients with non-ischaemic dilated cardiomyopathy
    Stephanie Lehrke
    Abteilung Innere Medizin III, Medizinische Klinik, Universitatsklinikum Heidelberg, Heidelberg, Germany
    Heart 97:727-32. 2011
    ..The goal of this study was to investigate the long-term prognostic significance of late gadolinium enhancement (LGE) as detected by contrast-enhanced cardiovascular magnetic resonance (CE-CMR) in patients with DCM...
  22. ncbi Effect of older age on diagnostic and prognostic performance of high-sensitivity troponin T in patients presenting to an emergency department
    Jeanette Normann
    Department of Internal Medicine III, Cardiology, University Hospital Heidelberg, Heidelberg, Germany
    Am Heart J 164:698-705.e4. 2012
    ..The effect of age on diagnostic and prognostic performance of high-sensitivity cardiac troponin T (hs-cTnT) has not been addressed adequately, so far...
  23. ncbi Strain-encoded MRI for evaluation of left ventricular function and transmurality in acute myocardial infarction
    Mirja Neizel
    Medical Clinic III, University Hospital Heidelberg, Heidelberg, Germany
    Circ Cardiovasc Imaging 2:116-22. 2009
    ....
  24. ncbi Serial and single time-point measurements of cardiac troponin T for prediction of clinical outcomes in patients with acute ST-segment elevation myocardial infarction
    Kerstin Kurz
    Abteilung Innere Medizin III, Medizinische Klinik, Universitatsklinikum Heidelberg, Im Neuenheimer Feld 410, 69120 Heidelberg, Germany
    Clin Res Cardiol 98:94-100. 2009
    ..Cardiac troponins are the preferred biomarkers to predict infarct size in patients (pts) after acute myocardial infarction (AMI). Less information is currently available to verify the prognostic value of such a biomarker surrogate...
  25. ncbi Determinants of troponin release in patients with stable coronary artery disease: insights from CT angiography characteristics of atherosclerotic plaque
    Grigorios Korosoglou
    University of Heidelberg, Department of Cardiology, Im Neuenheimer Feld 410, Heidelberg, 69120, Germany
    Heart 97:823-31. 2011
    ....
  26. ncbi Strain-encoded cardiac magnetic resonance during high-dose dobutamine stress testing for the estimation of cardiac outcomes: comparison to clinical parameters and conventional wall motion readings
    Grigorios Korosoglou
    Department of Cardiology, University of Heidelberg, Im Neuenheimer Feld 410, Heidelberg, Germany
    J Am Coll Cardiol 58:1140-9. 2011
    ....
  27. ncbi Quantitative assessment of stenosis severity and atherosclerotic plaque composition using 256-slice computed tomography
    Grigorios Korosoglou
    Department of Cardiology, University of Heidelberg, Heidelberg, Germany
    Eur Radiol 20:1841-50. 2010
    ....
  28. ncbi Tirofiban optimizes platelet inhibition for immediate percutaneous coronary intervention in high-risk acute coronary syndromes
    Boris T Ivandic
    Innere Medizin, Abt III, Universitatsklinikum Heidelberg, Im Neuenheimer Feld 410, 69120 Heidelberg, Germany
    Thromb Haemost 100:648-54. 2008
    ..Only tirofiban provided consistent and effective inhibition of platelet aggregation at the time of immediate or very early invasive therapy...
  29. ncbi Acute phase reaction to gadolinium-DTPA in dialysis patients
    Henning Steen
    Division of Cardiology, Department of Internal Medicine, University of Heidelberg, Heidelberg, Germany
    Nephrol Dial Transplant 24:1274-7. 2009
    ..In an observational series, we found a remarkable frequency of peracute reactions after administration of Gd-DTPA used for cardiovascular evaluation before renal transplantation...
  30. ncbi Usefulness of real-time myocardial perfusion imaging to evaluate alterations of myocardial blood flow in patients with stable angina pectoris undergoing elective percutaneous coronary interventions
    Grigorios Korosoglou
    Department of Cardiology, University of Heidelberg, Heidelberg, Germany
    Am J Cardiol 96:885-91. 2005
    ..Because judgment of interventional success has shifted downstream to tissue level perfusion, myocardial contrast echocardiography may be useful to monitor such alterations in myocardial tissue perfusion...
  31. ncbi Comparison of the new high sensitive cardiac troponin T with myoglobin, h-FABP and cTnT for early identification of myocardial necrosis in the acute coronary syndrome
    Kerstin Kurz
    Medizinische Klinik, Abteilung für Innere Medizin III, Universitatsklinikum Heidelberg, Im Neuenheimer Feld 410, Heidelberg, Germany
    Clin Res Cardiol 100:209-15. 2011
    ....
  32. ncbi Quantitative myocardial blush grade for the detection of cardiac allograft vasculopathy
    Grigorios Korosoglou
    University of Heidelberg, Department of Cardiology, Heidelberg, Germany
    Am Heart J 159:643-651.e2. 2010
    ..The aim of our study was to investigate the ability of quantitative myocardial blush grade (MBG) to detect CAV...
  33. ncbi Determination of myocardial infarct size by noncontact mapping
    Frederik Voss
    Department of Cardiology, University of Heidelberg, Heidelberg, Germany
    Heart Rhythm 5:308-14. 2008
    ..Dynamic substrate mapping (DSM) is an algorithm designed to identify conduction boundaries, such as myocardial scars based on voltage distribution within the corresponding chamber...
  34. ncbi Strain-encoded cardiac MR during high-dose dobutamine stress testing: comparison to cine imaging and to myocardial tagging
    Grigorios Korosoglou
    University of Heidelberg, Department of Cardiology, Heidelberg, Germany
    J Magn Reson Imaging 29:1053-61. 2009
    ..To investigate regional strain response during high-dose dobutamine stress cardiac magnetic resonance imaging (DS-CMR) using myocardial tagging and Strain-Encoded MR (SENC)...
  35. ncbi Strain-encoded cardiac MRI as an adjunct for dobutamine stress testing: incremental value to conventional wall motion analysis
    Grigorios Korosoglou
    Department of Cardiology, University of Heidelberg, Heidelberg, Germany
    Circ Cardiovasc Imaging 2:132-40. 2009
    ..The purpose of our study was to compare the diagnostic value of SENC with that provided by conventional wall motion analysis for the detection of inducible ischemia during dobutamine stress MRI...
  36. ncbi Prognostic value of high-dose dobutamine stress magnetic resonance imaging in 1,493 consecutive patients: assessment of myocardial wall motion and perfusion
    Grigorios Korosoglou
    Department of Cardiology, University of Heidelberg, Im Neuenheimer Feld 410, Heidelberg, Germany
    J Am Coll Cardiol 56:1225-34. 2010
    ..This study sought to determine the prognostic value of wall motion and perfusion assessment during high-dose dobutamine stress (DS) cardiac magnetic resonance imaging (MRI) in a large patient cohort...
  37. ncbi Reduction of radiation exposure and improvement of image quality with BMI-adapted prospective cardiac computed tomography and iterative reconstruction
    Waldemar Hosch
    University of Heidelberg, Department of Diagnostic and Interventional Radiology, Heidelberg, Germany
    Eur J Radiol 81:3568-76. 2012
    ....
  38. ncbi Green tea halts progression of cardiac transthyretin amyloidosis: an observational report
    Arnt V Kristen
    Department of Cardiology, Angiology, and Respiratory Medicine, University Hospital Heidelberg, Im Neuenheimer Feld 410, 69120 Heidelberg, Germany
    Clin Res Cardiol 101:805-13. 2012
    ..Thus, it might also halt progression of TTR amyloidosis. This is a single-center observational report on the effects of GT consumption in patients with ATTR cardiomopathy...
  39. ncbi Prevalence of different gadolinium enhancement patterns in patients after heart transplantation
    Henning Steen
    Abteilung Innere Medizin III, Medizinische Klinik, Universitatsklinikum Heidelberg, Heidelberg, Germany
    J Am Coll Cardiol 52:1160-7. 2008
    ..We hypothesized that contrast-enhanced magnetic resonance imaging (CE-MRI) detects chronic TCAD-related myocardial infarctions (MIs), even in patients with angiographically classified mild TCAD...
  40. ncbi Cardiac troponin T at 96 hours after acute myocardial infarction correlates with infarct size and cardiac function
    Henning Steen
    Abteilung Innere Medizin III, Medizinische Klinik, , Heidelberg, Germany
    J Am Coll Cardiol 48:2192-4. 2006
    ..The ability to quantify and the potential to distinguish effects of novel drug regimens on infarct size make cTnT attractive for routine practice and as a clinical end point...
  41. ncbi Quantitative analysis of left ventricular dyssynchrony using cardiac computed tomography versus three-dimensional echocardiography
    Sebastian J Buss
    Department of Cardiology, University of Heidelberg, Im Neuenheimer Feld 410, 69120 Heidelberg, Germany
    Eur Radiol 22:1303-9. 2012
    ....
  42. ncbi Usefulness of real-time myocardial perfusion imaging to evaluate tissue level reperfusion in patients with non-ST-elevation myocardial infarction
    Grigorios Korosoglou
    Department of Cardiology, University of Heidelberg, Heidelberg, Germany
    Am J Cardiol 95:1033-8. 2005
    ..Improvement of regional tissue perfusion after revascularization is closely related to functional recovery. This information may aid risk stratification and allow monitoring of the effectiveness of reperfusion therapy in these patients...
  43. ncbi In vitro evaluation of 56 coronary artery stents by 256-slice multi-detector coronary CT
    Henning Steen
    University of Heidelberg, Department of Cardiology, Im Neuenheimer Feld 410, Heidelberg 69120, Germany
    Eur J Radiol 80:143-50. 2011
    ..We sought to investigate stent lumen visibility of 56 coronary stents with the newest 256-multi-slice-CT (256-MDCT) technology for different reconstruction algorithms in an in vitro model...
  44. ncbi Myocardial late gadolinium enhancement cardiovascular magnetic resonance in patients with cirrhosis
    Dirk Lossnitzer
    Department of Internal Medicine III, University Hospital of Heidelberg, Im Neuenheimer Feld 410, 69120 Heidelberg, Germany
    J Cardiovasc Magn Reson 12:47. 2010
    ..We sought to identify myocardial tissue characterization and evaluate cardiovascular magnetic resonance (CMR) for diagnosis of cardiac impairment...
  45. ncbi Minor troponin T elevation in patients 6 months after acute myocardial infarction: an observational study
    Mirja Neizel
    Medical Clinic III, University Hospital Heidelberg, Heidelberg, Germany
    Clin Res Cardiol 98:297-304. 2009
    ....
  46. ncbi Image quality and radiation dose in 256-slice cardiac computed tomography: comparison of prospective versus retrospective image acquisition protocols
    Waldemar Hosch
    University of Heidelberg, Department of Diagnostic and Interventional Radiology, Heidelberg, Germany
    Eur J Radiol 80:127-35. 2011
    ..To assess coronary artery image quality and patient radiation exposure in patients who underwent clinically indicated 256-slice CTA...
  47. ncbi Absence of auto-antibodies against cardiac troponin I predicts improvement of left ventricular function after acute myocardial infarction
    Florian Leuschner
    Department of Internal Medicine III, Cardiology, University of Heidelberg, Im Neuenheimer Feld 410, 69120 Heidelberg, Germany
    Eur Heart J 29:1949-55. 2008
    ..Others have shown that auto-antibodies to cTnI are present in patients with acute coronary syndrome, but little is known about the clinical relevance of detected cTnI-Ab...
  48. ncbi Osteopontin, a new prognostic biomarker in patients with chronic heart failure
    Mark Rosenberg
    Department of Internal Medicine III, University of Heidelberg, Heidelberg, Germany
    Circ Heart Fail 1:43-9. 2008
    ..We therefore tested whether osteopontin plasma levels are elevated in patients with chronic heart failure and whether they provide independent prognostic information...
  49. ncbi Body mass index-adapted prospective coronary computed tomography angiography. Determining the lowest limit for diagnostic purposes
    Waldemar Hosch
    University of Heidelberg, Department of Diagnostic and Interventional Radiology, Heidelberg, Germany
    Eur J Radiol 82:e232-9. 2013
    ..To investigate the value of 4 different protocols for prospectively triggered 256-slice coronary computed tomography angiography (coronary CTA)...
  50. ncbi Performance of dual source versus 256-slice multi-slice CT in the evaluation of 16 coronary artery stents
    Florian André
    University of Heidelberg, Department of Cardiology, Im Neuenheimer Feld 410, Heidelberg, 69120, Germany
    Eur J Radiol 82:601-7. 2013
    ..We sought to compare the performance of DSCT and 256-MSCT for the in vitro assessment of stent lumen diameter and basic scan parameters in stents of various diameters and designs...
  51. ncbi Absolute and relative kinetic changes of high-sensitivity cardiac troponin T in acute coronary syndrome and in patients with increased troponin in the absence of acute coronary syndrome
    Matthias Mueller
    Department of Internal Medicine III, Cardiology, University Hospital Heidelberg, Heidelberg, Germany
    Clin Chem 58:209-18. 2012
    ....
  52. ncbi Soluble TWEAK is markedly upregulated in patients with ST-elevation myocardial infarction and related to an adverse short-term outcome
    Emmanuel Chorianopoulos
    Department of Cardiology, Angiology and Pulmology, Heidelberg University Hospital, Im Neuenheimer Feld 410, 69120 Heidelberg, Germany
    Atherosclerosis 211:322-6. 2010
    ..In this retrospective pilot study we thus sought to evaluate serum levels of soluble TWEAK (sTWEAK) patients with acute ST-elevation myocardial infarction (STEMI)...
  53. ncbi Hepatic and renal failure after anterior myocardial infarction induced apical ventricular septal defect
    Dirk Lossnitzer
    Division of Cardiology, Pneumology and Angiology, Department of Internal Medicine III, University of Heidelberg, 69120 Heidelberg, Germany
    Case Report Med 2010:645236. 2010
    ..To our knowledge, for the first time we report successful CAPD catheter drainage of hydroperitoneum in combination with CAPD hemodialysis...
  54. ncbi Contrast-enhanced magnetic resonance imaging reveals early decrease of transmural extent of reperfused acute myocardial infarction
    Constanze Merten
    Abteilung Innere Medizin III, Medizinische Klinik, Universitatsklinikum Heidelberg, 69120, Heidelberg, Germany
    Clin Res Cardiol 97:913-6. 2008
    ..We conclude that the transmural infarct extent is not stable over the first days after STEMI which should be taken into account when assessing viability in clinical and research settings...
  55. ncbi Troponins and high-sensitivity troponins as markers of necrosis in CAD and heart failure
    Evangelos Giannitsis
    Department of Internal Medicine III, University Hospital Heidelberg, Heidelberg, Germany
    Herz 34:600-6. 2009
    ..The causes of these elevations may be due to acute, subacute and chronic cardiac disease such as heart failure or cardiomyopathies...
  56. ncbi Cardiac biomarkers in haemodialysis patients: the prognostic value of amino-terminal pro-B-type natriuretic peptide and cardiac troponin T
    Claudia Sommerer
    Department of Nephrology, University Hospital of Heidelberg, Heidelberg, Germany
    Nephron Clin Pract 107:c77-81. 2007
    ..They provide a useful rationale for the screening of occult cardiac disease and optimization of the dialysis procedure with respect to volume control...
  57. ncbi Quantitative evaluation of myocardial blush to assess tissue level reperfusion in patients with acute ST-elevation myocardial infarction: incremental prognostic value compared with visual assessment
    Grigorios Korosoglou
    Department of Cardiology, University of Heidelberg, Heidelberg, Germany
    Am Heart J 153:612-20. 2007
    ..The purpose of the study was to test whether quantification of MBG can enhance the predictive value of visual assessment for functional recovery in patients with acute ST-elevation myocardial infarction (STEMI)...
  58. ncbi Biological variation and reference change value of high-sensitivity troponin T in healthy individuals during short and intermediate follow-up periods
    Lutz Frankenstein
    Department of Cardiology, Angiology, Pulmonology, University of Heidelberg, Heidelberg, Germany
    Clin Chem 57:1068-71. 2011
    ....
  59. ncbi Highly sensitive cardiac troponin T values remain constant after brief exercise- or pharmacologic-induced reversible myocardial ischemia
    Kerstin Kurz
    Department of Medicine III, University of Heidelberg, Im Neuenheimer Feld 410, Heidelberg, Germany
    Clin Chem 54:1234-8. 2008
    ..Using a new precommercial high-sensitivity cardiac troponin T (hsTnT) assay, we evaluated whether hsTnT increases after reversible myocardial ischemia...
  60. ncbi Elevated myocardial enzymes and natriuretic peptides in anorexia nervosa: prototypic condition for the pathophysiology of cachexia?
    Arne Zastrow
    Department of General Internal Medicine and Psychosomatics, University of Heidelberg, Heidelberg, Germany
    Cardiology 118:256-9. 2011
    ..A review of the available literature is provided. Further research is required to explain the pathophysiological meaning of the abnormal laboratory findings...
  61. ncbi Combined testing of high-sensitivity troponin T and copeptin on presentation at prespecified cutoffs improves rapid rule-out of non-ST-segment elevation myocardial infarction
    Evangelos Giannitsis
    Medizinische Klinik, Abteilung für Innere Medizin III, Universitatsklinikum Heidelberg, Heidelberg, Germany
    Clin Chem 57:1452-5. 2011
    ....
  62. ncbi Images in cardiovascular medicine. A rare form of midventricular Tako-Tsubo after emotional stress followed up with magnetic resonance imaging
    Henning Steen
    Division of Cardiology, Pneumology, and Angiology, Department of Internal Medicine III, University of Heidelberg, Im Neuenheimer Feld 410, 69120 Heidelberg, Germany
    Circulation 114:e248. 2006
  63. ncbi Anomalous origin of the left circumflex coronary artery from the pulmonary artery. A very rare congenital anomaly in an adult patient diagnosed by cardiovascular magnetic resonance
    Grigorios Korosoglou
    Department of Cardiology, University of Heidelberg, Heidelberg, Germany
    J Cardiovasc Magn Reson 10:4. 2008
    ..CMR provided the unambiguous depiction of the origin of the anomalous LCX from the right pulmonary artery and the delineation of its proximal course in this case of a very rare coronary anomaly in adults...
  64. ncbi Rationale for testing the cardiovascular risk for patients with COX-2 inhibitors on the basis of biomarker NT-proBNP
    Evangelos Giannitsis
    Department of Internal Medicine III Cardiology, Medical Clinic, Heidelberg University Hospital, Heidelberg, Germany
    Clin Lab 51:63-83. 2005
    ..Follow-up with NT-proBNP (monitoring) can be helpful in detecting imminent cardiac decompensation at an earlier stage in order to take suitable countermeasures...
  65. ncbi High-sensitive troponin T: a novel biomarker for prognosis and disease severity in patients with pulmonary arterial hypertension
    Arthur Filusch
    Department of Cardiology, Angiology and Respiratory Medicine, University Medical Center, Im Neuenheimer Feld 410, D 69120 Heidelberg, Germany
    Clin Sci (Lond) 119:207-13. 2010
    ..In conclusion, in PAH patients, the novel biomarker hsTnT is associated with death and advanced WHO functional class, and is related to systolic right ventricular dysfunction and an impaired 6-min walk distance...
  66. ncbi Cardiospecificity of the 3rd generation cardiac troponin T assay during and after a 216 km ultra-endurance marathon run in Death Valley
    H J Roth
    Laboratory Dr Limbach and Colleagues, Heidelberg, Germany
    Clin Res Cardiol 96:359-64. 2007
    ..The aim of the present study was to evaluate the cardiospecificity of the 3(rd) generation cardiac cTnT assay during and after an ultra-endurance race of 216 km at extreme environmental conditions in Death Valley...
  67. ncbi Assessment of disease severity and outcome in patients with systemic light-chain amyloidosis by the high-sensitivity troponin T assay
    Arnt V Kristen
    Department of Cardiology, Angiology, and Respiratory Medicine, Heidelberg University, Heidelberg, Germany
    Blood 116:2455-61. 2010
    ..Plasma levels of the hs-TnT assay are associated with the clinical, morphologic, and functional severity of cardiac AL amyloidosis and could provide useful information for clinicians on cardiac involvement and outcome...
  68. ncbi [Diagnosis of ischemia]
    Kerstin Kurz
    Abteilung Innere Medizin III, Medizinische Klinik, , Heidelberg
    Herz 29:575-81. 2004
    ..Consecutively, patients without high-risk features need a thorough noninvasive evaluation for the presence of significant CAD which is comparable to patients presenting with chronic stable angina pectoris...
  69. ncbi Visualization of a coronary fistula with pulmonary drainage
    Henning Steen
    Division of Cardiology, Pneumology and Angiology, Department of Internal Medicine III, University of Heidelberg, Im Neuenheimer Feld 410, 69120, Heidelberg, Germany
    Clin Res Cardiol 95:355-6. 2006
  70. ncbi Beta2-integrin activation on T cell subsets is an independent prognostic factor in unstable angina pectoris
    Mathias H Konstandin
    Dept of Cardiology, Ruprecht Karls University, Heidelberg, Germany
    Basic Res Cardiol 104:341-51. 2009
    ..Beta2-integrin mediated T cell recruitment plays a pivotal role in coronary atherosclerotic plaque rupture. The present study investigates beta2-integrin activation on T cell subsets as a risk marker in UA...
  71. ncbi Aortic intramural hematoma in a 17-year-old patient with dysphagia
    Raffi Bekeredjian
    Department of Cardiology, University of Heidelberg, Heidelberg, Germany
    Clin Cardiol 29:373. 2006
  72. ncbi Determination of clopidogrel resistance by whole blood platelet aggregometry and inhibitors of the P2Y12 receptor
    Boris T Ivandic
    Department of Medicine III, University of Heidelberg, Heidelberg, Germany
    Clin Chem 52:383-8. 2006
    ..Inhibition of platelet aggregation by clopidogrel may be insufficient in up to 30% of users. These nonresponders carry an increased risk of cardiovascular events. We reported here a simple assay to study clopidogrel responsiveness...
  73. ncbi Anomalous right coronary artery arising next to the left coronary ostium Unambiguous detection of the anatomy by computed tomography and evaluation of functional significance by cardiovascular magnetic resonance
    Grigorios Korosoglou
    Department of Cardiology, University of Heidelberg, Heidelberg, Germany
    Int J Cardiol 145:e50-3. 2010
    ..CMR during adenosine infusion ruled-out inducible ischemia, yielding normal perfusion patterns both in the RCA and in the LAD coronary territory. Since ischemia was not demonstrated by stress CMR, revascularization was not performed...
  74. ncbi Large-scale mutation screening in patients with dilated or hypertrophic cardiomyopathy: a pilot study using DGGE
    Raphael Zeller
    Innere Medizin III, , Im Neuenheimer Feld 410, 69120 Heidelberg, Germany
    J Mol Med 84:682-91. 2006
    ..The platform proved a valuable contribution to elucidating the genetic causes of DCM and HCM as demonstrated by the identification of 17 different known and novel mutations and 98 different polymorphisms in our setting...
  75. ncbi Comparison of cardiac troponin T and troponin I assays--implications of analytical and biochemical differences on clinical performance
    Evangelos Giannitsis
    Abteilung Innere Medizin III, Medizinische Klinik und Poliklinik, Universitatsklinikum Heidelberg
    Clin Lab 50:521-8. 2004
    ..The present review will provide a state-of-the-art overview on the performance of cardiac troponins in acute coronary disease and other clinical conditions...
  76. ncbi Usefulness of real-time myocardial perfusion imaging in the evaluation of patients with first time chest pain
    Grigorios Korosoglou
    Department of Cardiology, University of Heidelberg, Heidelberg, Germany
    Am J Cardiol 94:1225-31. 2004
    ..73, p <0.001) and with ejection fraction at 4 weeks of follow-up (r = -0.79, p <0.001). Thus, our data suggest that MCE can accurately identify patients who have ACS...
  77. ncbi [Indicators of plaque stability]
    Henning Steen
    Medizinische Klinik II,
    Herz 27:64-7. 2002
  78. ncbi Admission troponin T, advanced age and male gender identify patients with improved myocardial tissue perfusion after abciximab administration for ST-segment elevation myocardial infarction
    Stephanie Lehrke
    , Department of Cardiology, Bergheimer Strasse 58, 69115 Heidelberg, Germany
    Thromb Haemost 92:1214-20. 2004
    ..1 microg/L on admission, age over 70 years and male gender...
  79. ncbi Cardiac biomarkers for detection of myocardial infarction: perspectives from past to present
    Sidney B Rosalki
    10 Wimpole News, London, United Kingdom
    Clin Chem 50:2205-13. 2004
    ....
  80. ncbi Cardiac troponin elevations in patients without acute coronary syndrome
    Christian W Hamm
    Circulation 106:2871-2. 2002
  81. ncbi Troponin T release in hemodialysis patients
    Evangelos Giannitsis
    Circulation 110:e25-6; author reply e25-6. 2004
  82. ncbi Prognostic significance of admission cardiac troponin T in patients treated successfully with direct percutaneous interventions for acute ST-segment elevation myocardial infarction
    Volkhard Kurowski
    Medizinische Klinik II, , Germany
    Crit Care Med 30:2229-35. 2002
    ....
  83. ncbi Still unresolved issues with brain-type natriuretic peptide measurement in the critically ill patient
    Evangelos Giannitsis
    Crit Care Med 31:2703-4. 2003
  84. ncbi Temporal repolarization inhomogeneity and reperfusion arrhythmias in patients undergoing successful primary percutaneous coronary intervention for acute ST-segment elevation myocardial infarction: impact of admission troponin T
    Hendrik Bonnemeier
    Medizinische Klinik II, Medizinische Universitat zu Lubeck, Lubeck, Germany
    Am Heart J 145:484-92. 2003
    ....
  85. ncbi Cardiac troponin T for prediction of short- and long-term morbidity and mortality after elective open heart surgery
    Stephanie Lehrke
    Johns Hopkins University, Department of Cardiology, Baltimore, MD, USA
    Clin Chem 50:1560-7. 2004
    ..CONCLUSIONS: A single postoperative cTnT measurement can be used to estimate myocardial cell injury that impacts long-term survival after open heart surgery. It adds independently to established risk indicators...
  86. ncbi Time-dependent changes of hs-CRP serum concentration in patients with non-ST elevation acute coronary syndrome
    Jürgen Jahn
    Department of Internal Medicine, Borromäus Hospital, Leer, Germany
    Herz 29:795-801. 2004
    ..Therefore, it is interesting to discuss the value of follow-up measurements of hs-CRP in patients with coronary artery disease (CAD)...
  87. ncbi Very early cardiac magnetic resonance imaging for quantification of myocardial tissue perfusion in patients receiving tirofiban before percutaneous coronary intervention for ST-elevation myocardial infarction
    Henning Steen
    Department of Medicine, Division of Cardiology, Johns Hopkins Medical Institutions, Baltimore, MD, USA
    Am Heart J 149:564. 2005
    ..Magnetic resonance imaging proved useful as a complementary method for noninvasive assessment of myocardial blood flow and cardiac function in patients with ST-segment elevation myocardial infarction undergoing primary PCI...
  88. ncbi N-terminal pro-B-type natriuretic peptide concentrations predict the risk of cardiovascular adverse events from antiinflammatory drugs: a pilot trial
    Kay Brune
    Department of Experimental and Clinical Pharmacology and Toxicology, Friedrich Alexander University of Erlangen Nuremberg, Erlangen, Germany
    Clin Chem 54:1149-57. 2008
    ..we investigated whether higher concentrations of N-terminal pro-B-type natriuretic peptide (NT-proBNP) predicts cardiovascular adverse events (CV-AEs) in patients with osteoarthritis treated with antiinflammatory drugs...
  89. ncbi N-terminal prohormone brain natriuretic peptide: a biomarker for detecting cardiovascular risks in patients with rheumatoid arthritis or osteoarthritis?
    Thomas Häupl
    Ann Rheum Dis 66:838-9. 2007
  90. ncbi Determination of aspirin responsiveness by use of whole blood platelet aggregometry
    Boris T Ivandic
    Department of Medicine III, University of Heidelberg, Germany
    Clin Chem 53:614-9. 2007
    ..Insufficient platelet inhibition is associated with an increased cardiovascular risk in up to 30% of patients taking regular doses of aspirin. We describe an assay to study aspirin responsiveness...
  91. ncbi The effects of facilitated primary PCI by guide wire on procedural and clinical outcomes in acute ST-segment elevation myocardial infarction
    Volkhard Kurowski
    Medizinische Klinik II, Medizinische Universitat zu Lubeck, Ratzeburger Allee 160, 23538, Lubeck, Germany
    Clin Res Cardiol 96:557-65. 2007
    ....
  92. ncbi Prehospital initiation of tirofiban in patients with ST-elevation myocardial infarction undergoing primary angioplasty (On-TIME 2): a multicentre, double-blind, randomised controlled trial
    Arnoud W J Van't Hof
    Isala Klinieken, Department of Cardiology, Zwolle, Netherlands
    Lancet 372:537-46. 2008
    ..We investigated whether the results of primary coronary angioplasty (PCI) can be improved by the early administration of the glycoprotein IIb/IIIa blocker tirofiban at first medical contact in the ambulance or referral centre...
  93. ncbi Risk stratification in pulmonary embolism based on biomarkers and echocardiography
    Evangelos Giannitsis
    Circulation 112:1520-1. 2005
  94. ncbi The tako-tsubo syndrome: an underappreciated, novel disease entity
    Norbert Frey
    Chest 132:743-4. 2007
  95. ncbi Massive trabecular hypertrophy of the entire right ventricle resembling right ventricular non-compaction in a patient with low pressure giant pulmonary artery aneurysm
    Henning Steen
    Clin Res Cardiol 96:822-3. 2007
  96. ncbi Relationship of MRI-determined infarct size and cTnI measurements in patients with ST-elevation myocardial infarction
    Vlad C Vasile
    Clin Chem 54:617-9. 2008
  97. ncbi Mirror, mirror on the wall: the quest for the earliest marker of myocardial ischaemia
    Evangelos Giannitsis
    Eur Heart J 26:2349-50. 2005
  98. ncbi Images in cardiovascular medicine. Hereditary hypertrophic nonobstructive cardiomyopathy seen on delayed hyperenhancement magnetic resonance imaging
    Henning Steen
    Division of Cardiology, Pneumology, and Angiology, Department of Internal Medicine III, University of Heidelberg, Germany
    Circulation 113:e458-9. 2006
  99. ncbi Prompt resolution of an apical left ventricular thrombus in a patient with takotsubo cardiomyopathy
    Grigorios Korosoglou
    Int J Cardiol 116:e88-91. 2007
    ..The patient was diagnosed with takotsubo cardiomyopathy...
  100. ncbi Differential diagnosis of elevated troponins
    Susanne Korff
    Department of Medicine III, University of Heidelberg, Germany
    Heart 92:987-93. 2006
  101. ncbi Release kinetics of cardiac troponin T in survivors of confirmed severe pulmonary embolism
    Margit Müller-Bardorff
    Universitatsklinikum Lubeck, Medizinische Klinik II, Ratzeburger Allee 160, 23538 Lubeck, Germany
    Clin Chem 48:673-5. 2002