Evangelos Giannitsis

Summary

Affiliation: University of Heidelberg
Country: Germany

Publications

  1. ncbi request reprint 99th percentile and analytical imprecision of troponin and creatine kinase-MB mass assays: an objective platform for comparison of assay performance
    Evangelos Giannitsis
    Clin Chem 49:1248-9. 2003
  2. ncbi request reprint Multicentre evaluation of a new point-of-care test for the determination of CK-MB in whole blood
    Evangelos Giannitsis
    Abteilung fur Kardiologie, Angiologie und Pulmonologie, Universitatsklinikum Heidelberg, Heidelberg, Germany
    Clin Chem Lab Med 46:630-8. 2008
  3. doi request reprint Cardiac magnetic resonance imaging study for quantification of infarct size comparing directly serial versus single time-point measurements of cardiac troponin T
    Evangelos Giannitsis
    Abteilung Innere Medizin III, Medizinische Klinik, Universitatsklinikum Heidelberg, Heidelberg, Germany
    J Am Coll Cardiol 51:307-14. 2008
  4. ncbi request reprint Multimarker strategy in acute coronary syndrome--pro-multimarker
    Evangelos Giannitsis
    Abteilung Innere Medizin III, Medizinische Klinik, Universitatsklinikum Heidelberg, 69120 Heidelberg, Germany
    Acute Card Care 9:6-9. 2007
  5. ncbi request reprint Risk stratification in pulmonary embolism based on biomarkers and echocardiography
    Evangelos Giannitsis
    Circulation 112:1520-1. 2005
  6. doi request reprint Pros and cons of high-sensitivity assays for cardiac troponin
    Evangelos Giannitsis
    Department of Internal Medicine III, Cardiology, University Hospital Heidelberg, Im Neuenheimer Feld 410, 69120 Heidelberg, Germany
    Nat Rev Cardiol 9:616-8. 2012
  7. doi request reprint Antiplatelet therapy - ticagrelor
    E Giannitsis
    Department of Internal Medicine III, Cardiology, University Hospital Heidelberg, Germany
    Hamostaseologie 32:177-85. 2012
  8. doi request reprint High-sensitivity cardiac troponin T for early prediction of evolving non-ST-segment elevation myocardial infarction in patients with suspected acute coronary syndrome and negative troponin results on admission
    Evangelos Giannitsis
    Medizinische Klinik, Abteilung für Innere Medizin III, Universitatsklinikum Heidelberg, Heidelberg, Germany
    Clin Chem 56:642-50. 2010
  9. doi request reprint Analytical validation of a high-sensitivity cardiac troponin T assay
    Evangelos Giannitsis
    Medizinische Klinik, Abteilung für Innere Medizin III, Universitatsklinikum Heidelberg, Germany
    Clin Chem 56:254-61. 2010
  10. doi request reprint Strain-encoded CMR for the detection of inducible ischemia during intermediate stress
    Grigorios Korosoglou
    University of Heidelberg, Department of Cardiology, Heidelberg, Germany
    JACC Cardiovasc Imaging 3:361-71. 2010

Detail Information

Publications109 found, 100 shown here

  1. ncbi request reprint 99th percentile and analytical imprecision of troponin and creatine kinase-MB mass assays: an objective platform for comparison of assay performance
    Evangelos Giannitsis
    Clin Chem 49:1248-9. 2003
  2. ncbi request reprint Multicentre evaluation of a new point-of-care test for the determination of CK-MB in whole blood
    Evangelos Giannitsis
    Abteilung fur Kardiologie, Angiologie und Pulmonologie, Universitatsklinikum Heidelberg, Heidelberg, Germany
    Clin Chem Lab Med 46:630-8. 2008
    ..The point-of-care (POC) test Roche CARDIAC CK-MB is a new assay which has been developed for the existing Roche Cardiac reader system...
  3. doi request reprint Cardiac magnetic resonance imaging study for quantification of infarct size comparing directly serial versus single time-point measurements of cardiac troponin T
    Evangelos Giannitsis
    Abteilung Innere Medizin III, Medizinische Klinik, Universitatsklinikum Heidelberg, Heidelberg, Germany
    J Am Coll Cardiol 51:307-14. 2008
    ..We compared single-point cardiac troponin T (cTnT) measurements with parameters from serial sampling during 96 h after acute myocardial infarction with magnetic resonance imaging measured infarct mass...
  4. ncbi request reprint Multimarker strategy in acute coronary syndrome--pro-multimarker
    Evangelos Giannitsis
    Abteilung Innere Medizin III, Medizinische Klinik, Universitatsklinikum Heidelberg, 69120 Heidelberg, Germany
    Acute Card Care 9:6-9. 2007
  5. ncbi request reprint Risk stratification in pulmonary embolism based on biomarkers and echocardiography
    Evangelos Giannitsis
    Circulation 112:1520-1. 2005
  6. doi request reprint Pros and cons of high-sensitivity assays for cardiac troponin
    Evangelos Giannitsis
    Department of Internal Medicine III, Cardiology, University Hospital Heidelberg, Im Neuenheimer Feld 410, 69120 Heidelberg, Germany
    Nat Rev Cardiol 9:616-8. 2012
    ..Whether faster rule-out algorithms can discriminate between MI and other conditions that elevate the troponin level, or be safely implemented across the whole spectrum of patient risk, is unclear...
  7. doi request reprint Antiplatelet therapy - ticagrelor
    E Giannitsis
    Department of Internal Medicine III, Cardiology, University Hospital Heidelberg, Germany
    Hamostaseologie 32:177-85. 2012
    ....
  8. doi request reprint High-sensitivity cardiac troponin T for early prediction of evolving non-ST-segment elevation myocardial infarction in patients with suspected acute coronary syndrome and negative troponin results on admission
    Evangelos Giannitsis
    Medizinische Klinik, Abteilung für Innere Medizin III, Universitatsklinikum Heidelberg, Heidelberg, Germany
    Clin Chem 56:642-50. 2010
    ..We sought to determine the diagnostic performance of the new high-sensitivity cardiac troponin T (hs-cTnT) assay for early detection of non-ST-segment myocardial infarction (NSTEMI) in patients with acute coronary syndrome...
  9. doi request reprint Analytical validation of a high-sensitivity cardiac troponin T assay
    Evangelos Giannitsis
    Medizinische Klinik, Abteilung für Innere Medizin III, Universitatsklinikum Heidelberg, Germany
    Clin Chem 56:254-61. 2010
    ..We report the development of a novel high-sensitivity cardiac troponin T (hs-cTnT) assay, a modification of the Roche fourth-generation cTnT assay, and validation of the analytical performance of this assay...
  10. doi request reprint Strain-encoded CMR for the detection of inducible ischemia during intermediate stress
    Grigorios Korosoglou
    University of Heidelberg, Department of Cardiology, Heidelberg, Germany
    JACC Cardiovasc Imaging 3:361-71. 2010
    ..This study sought to evaluate the diagnostic accuracy of strain-encoded cardiac magnetic resonance (SENC) for the detection of inducible ischemia during intermediate stress...
  11. pmc Staged cardiovascular magnetic resonance for differential diagnosis of troponin T positive patients with low likelihood for acute coronary syndrome
    Henning Steen
    Abteilung Innere Medizin III, Medizinische Klinik, Universitatsklinikum Heidelberg, Heidelberg, Germany
    J Cardiovasc Magn Reson 12:51. 2010
    ....
  12. doi request reprint Early assessment of infarct size and prediction of functional recovery by quantitative myocardial blush grade in patients with acute coronary syndromes treated according to current guidelines
    Nina Riedle
    Department of Cardiology, University of Heidelberg, Heidelberg, Germany
    Catheter Cardiovasc Interv 76:502-10. 2010
    ....
  13. doi request reprint Predicting microvascular obstruction with cardiac troponin T after acute myocardial infarction: a correlative study with contrast-enhanced magnetic resonance imaging
    Mirja Neizel
    Medical Clinic III, University Hospital Heidelberg, Heidelberg, 69120, Germany
    Clin Res Cardiol 98:555-62. 2009
    ..The aim of this study was to evaluate whether a single cardiac troponin T-value (cTnT) was able to predict the presence of MVO and whether cTnT is an independent predictor of MVO as compared to usual risk factors...
  14. doi request reprint Clinical feasibility study for detection of myocardial oedema by a cine SSFP sequence in comparison to a conventional T2-weighted sequence
    Henning Steen
    Department of Cardiology, University Hospital Heidelberg, Im Neuenheimer Feld 410, 69120, Heidelberg, Germany
    Clin Res Cardiol 101:125-31. 2012
    ..We therefore sought to prospectively evaluate SSFP cine-imaging to detect myocardial oedema and differentiate AMI from CMI...
  15. ncbi request reprint Relative role of NT-pro BNP and cardiac troponin T at 96 hours for estimation of infarct size and left ventricular function after acute myocardial infarction
    Henning Steen
    Abteilung Innere Medizin III, Medizinische Klinik, Universitatsklinikum Heidelberg, Heidelberg, Germany
    J Cardiovasc Magn Reson 9:749-58. 2007
    ..The aim of the present study was to correlate infarct size and left ventricular function determined by cine and late gadolinium enhanced CMR with plasma levels of TNT and NT-pro BNP levels after AMI...
  16. doi request reprint Longitudinal left ventricular function for prediction of survival in systemic light-chain amyloidosis: incremental value compared with clinical and biochemical markers
    Sebastian J Buss
    Department of Cardiology, University of Heidelberg, Heidelberg, Germany
    J Am Coll Cardiol 60:1067-76. 2012
    ..The aim of the study was to determine whether longitudinal left ventricular (LV) function provides prognostic information in a large cohort of patients with systemic light-chain (AL) amyloidosis...
  17. pmc Prediction of coronary artery disease by a systemic atherosclerosis score index derived from whole-body MR angiography
    Stephanie Lehrke
    Abteilung Innere Medizin III, Medizinische Klinik, Universitatsklinikum Heidelberg, Heidelberg, Germany
    J Cardiovasc Magn Reson 11:36. 2009
    ....
  18. doi request reprint Impact of systolic and diastolic deformation indexes assessed by strain-encoded imaging to predict persistent severe myocardial dysfunction in patients after acute myocardial infarction at follow-up
    Mirja Neizel
    Department of Cardiology, University Hospital Heidelberg, Heidelberg, Germany
    J Am Coll Cardiol 56:1056-62. 2010
    ....
  19. doi request reprint Serum levels of NT-proBNP as surrogate for cardiac amyloid burden: new evidence from gadolinium-enhanced cardiac magnetic resonance imaging in patients with amyloidosis
    Stephanie Lehrke
    Department of Medicine III, Division of Cardiology, University Hospital Heidelberg, Heidelberg, Germany
    Amyloid 16:187-95. 2009
    ..We aimed to use contrast enhanced cardiac magnetic resonance imaging (CMR) to identify functional and structural alterations related to levels of NT-proBNP better to understand the mechanisms of its release in cardiac amyloidosis...
  20. doi request reprint Use of cardiovascular magnetic resonance for risk stratification in chronic heart failure: prognostic value of late gadolinium enhancement in patients with non-ischaemic dilated cardiomyopathy
    Stephanie Lehrke
    Abteilung Innere Medizin III, Medizinische Klinik, Universitatsklinikum Heidelberg, Heidelberg, Germany
    Heart 97:727-32. 2011
    ..The goal of this study was to investigate the long-term prognostic significance of late gadolinium enhancement (LGE) as detected by contrast-enhanced cardiovascular magnetic resonance (CE-CMR) in patients with DCM...
  21. doi request reprint Strain-encoded (SENC) magnetic resonance imaging to evaluate regional heterogeneity of myocardial strain in healthy volunteers: Comparison with conventional tagging
    Mirja Neizel
    Department of Cardiology, University Hospital Heidelberg, Heidelberg, Germany
    J Magn Reson Imaging 29:99-105. 2009
    ..To evaluate the ability of strain-encoded (SENC) magnetic resonance imaging (MRI) for regional systolic and diastolic strain analysis of the myocardium in healthy volunteers...
  22. doi request reprint Body mass index-adapted prospective coronary computed tomography angiography. Determining the lowest limit for diagnostic purposes
    Waldemar Hosch
    University of Heidelberg, Department of Diagnostic and Interventional Radiology, Heidelberg, Germany
    Eur J Radiol 82:e232-9. 2013
    ..To investigate the value of 4 different protocols for prospectively triggered 256-slice coronary computed tomography angiography (coronary CTA)...
  23. doi request reprint Effect of older age on diagnostic and prognostic performance of high-sensitivity troponin T in patients presenting to an emergency department
    Jeanette Normann
    Department of Internal Medicine III, Cardiology, University Hospital Heidelberg, Heidelberg, Germany
    Am Heart J 164:698-705.e4. 2012
    ..The effect of age on diagnostic and prognostic performance of high-sensitivity cardiac troponin T (hs-cTnT) has not been addressed adequately, so far...
  24. doi request reprint Serial and single time-point measurements of cardiac troponin T for prediction of clinical outcomes in patients with acute ST-segment elevation myocardial infarction
    Kerstin Kurz
    Abteilung Innere Medizin III, Medizinische Klinik, Universitatsklinikum Heidelberg, Im Neuenheimer Feld 410, 69120 Heidelberg, Germany
    Clin Res Cardiol 98:94-100. 2009
    ..Cardiac troponins are the preferred biomarkers to predict infarct size in patients (pts) after acute myocardial infarction (AMI). Less information is currently available to verify the prognostic value of such a biomarker surrogate...
  25. ncbi request reprint Strain-encoded MRI for evaluation of left ventricular function and transmurality in acute myocardial infarction
    Mirja Neizel
    Medical Clinic III, University Hospital Heidelberg, Heidelberg, Germany
    Circ Cardiovasc Imaging 2:116-22. 2009
    ....
  26. doi request reprint Determinants of troponin release in patients with stable coronary artery disease: insights from CT angiography characteristics of atherosclerotic plaque
    Grigorios Korosoglou
    University of Heidelberg, Department of Cardiology, Im Neuenheimer Feld 410, Heidelberg, 69120, Germany
    Heart 97:823-31. 2011
    ....
  27. doi request reprint Comparison of a 3-hour versus a 6-hour sampling-protocol using high-sensitivity cardiac troponin T for rule-out and rule-in of non-STEMI in an unselected emergency department population
    Moritz Biener
    Department of Internal Medicine III, Cardiology, University Hospital Heidelberg, Germany
    Int J Cardiol 167:1134-40. 2013
    ..Current European guidelines recommend the use of sensitive or high-sensitivity cardiac troponin assays to reduce the minimal sampling interval from 6 to 3h...
  28. ncbi request reprint Cardiac troponin T: from diagnosis of myocardial infarction to cardiovascular risk prediction
    Matthias Mueller
    Department of Internal Medicine III, Cardiology, Angiology and Pneumology, University of Heidelberg, Heidelberg, Germany
    Circ J 77:1653-61. 2013
    ..Thus, it is highly likely that lowering the diagnostic cut-off with even more sensitive assays might improve risk stratification in both conditions...
  29. doi request reprint Performance of dual source versus 256-slice multi-slice CT in the evaluation of 16 coronary artery stents
    Florian André
    University of Heidelberg, Department of Cardiology, Im Neuenheimer Feld 410, Heidelberg, 69120, Germany
    Eur J Radiol 82:601-7. 2013
    ..We sought to compare the performance of DSCT and 256-MSCT for the in vitro assessment of stent lumen diameter and basic scan parameters in stents of various diameters and designs...
  30. doi request reprint Quantitative assessment of stenosis severity and atherosclerotic plaque composition using 256-slice computed tomography
    Grigorios Korosoglou
    Department of Cardiology, University of Heidelberg, Heidelberg, Germany
    Eur Radiol 20:1841-50. 2010
    ....
  31. ncbi request reprint Tirofiban optimizes platelet inhibition for immediate percutaneous coronary intervention in high-risk acute coronary syndromes
    Boris T Ivandic
    Innere Medizin, Abt III, Universitatsklinikum Heidelberg, Im Neuenheimer Feld 410, 69120 Heidelberg, Germany
    Thromb Haemost 100:648-54. 2008
    ..Only tirofiban provided consistent and effective inhibition of platelet aggregation at the time of immediate or very early invasive therapy...
  32. doi request reprint Strain-encoded cardiac magnetic resonance during high-dose dobutamine stress testing for the estimation of cardiac outcomes: comparison to clinical parameters and conventional wall motion readings
    Grigorios Korosoglou
    Department of Cardiology, University of Heidelberg, Im Neuenheimer Feld 410, Heidelberg, Germany
    J Am Coll Cardiol 58:1140-9. 2011
    ....
  33. doi request reprint Quantitative myocardial blush grade for the detection of cardiac allograft vasculopathy
    Grigorios Korosoglou
    University of Heidelberg, Department of Cardiology, Heidelberg, Germany
    Am Heart J 159:643-651.e2. 2010
    ..The aim of our study was to investigate the ability of quantitative myocardial blush grade (MBG) to detect CAV...
  34. doi request reprint Acute phase reaction to gadolinium-DTPA in dialysis patients
    Henning Steen
    Division of Cardiology, Department of Internal Medicine, University of Heidelberg, Heidelberg, Germany
    Nephrol Dial Transplant 24:1274-7. 2009
    ..In an observational series, we found a remarkable frequency of peracute reactions after administration of Gd-DTPA used for cardiovascular evaluation before renal transplantation...
  35. doi request reprint Comparison of the new high sensitive cardiac troponin T with myoglobin, h-FABP and cTnT for early identification of myocardial necrosis in the acute coronary syndrome
    Kerstin Kurz
    Medizinische Klinik, Abteilung für Innere Medizin III, Universitatsklinikum Heidelberg, Im Neuenheimer Feld 410, Heidelberg, Germany
    Clin Res Cardiol 100:209-15. 2011
    ....
  36. ncbi request reprint Usefulness of real-time myocardial perfusion imaging to evaluate alterations of myocardial blood flow in patients with stable angina pectoris undergoing elective percutaneous coronary interventions
    Grigorios Korosoglou
    Department of Cardiology, University of Heidelberg, Heidelberg, Germany
    Am J Cardiol 96:885-91. 2005
    ..Because judgment of interventional success has shifted downstream to tissue level perfusion, myocardial contrast echocardiography may be useful to monitor such alterations in myocardial tissue perfusion...
  37. doi request reprint Strain-encoded cardiac MR during high-dose dobutamine stress testing: comparison to cine imaging and to myocardial tagging
    Grigorios Korosoglou
    University of Heidelberg, Department of Cardiology, Heidelberg, Germany
    J Magn Reson Imaging 29:1053-61. 2009
    ..To investigate regional strain response during high-dose dobutamine stress cardiac magnetic resonance imaging (DS-CMR) using myocardial tagging and Strain-Encoded MR (SENC)...
  38. doi request reprint Determination of myocardial infarct size by noncontact mapping
    Frederik Voss
    Department of Cardiology, University of Heidelberg, Heidelberg, Germany
    Heart Rhythm 5:308-14. 2008
    ..Dynamic substrate mapping (DSM) is an algorithm designed to identify conduction boundaries, such as myocardial scars based on voltage distribution within the corresponding chamber...
  39. pmc Strain-encoded cardiac MRI as an adjunct for dobutamine stress testing: incremental value to conventional wall motion analysis
    Grigorios Korosoglou
    Department of Cardiology, University of Heidelberg, Heidelberg, Germany
    Circ Cardiovasc Imaging 2:132-40. 2009
    ..The purpose of our study was to compare the diagnostic value of SENC with that provided by conventional wall motion analysis for the detection of inducible ischemia during dobutamine stress MRI...
  40. doi request reprint Prognostic value of high-dose dobutamine stress magnetic resonance imaging in 1,493 consecutive patients: assessment of myocardial wall motion and perfusion
    Grigorios Korosoglou
    Department of Cardiology, University of Heidelberg, Im Neuenheimer Feld 410, Heidelberg, Germany
    J Am Coll Cardiol 56:1225-34. 2010
    ..This study sought to determine the prognostic value of wall motion and perfusion assessment during high-dose dobutamine stress (DS) cardiac magnetic resonance imaging (MRI) in a large patient cohort...
  41. pmc When do we really need coronary calcium scoring prior to contrast-enhanced coronary computed tomography angiography? Analysis by age, gender and coronary risk factors
    Gitsios Gitsioudis
    University of Heidelberg, Department of Cardiology, Heidelberg, Germany
    PLoS ONE 9:e92396. 2014
    ..To investigate the value of coronary calcium scoring (CCS) as a filter scan prior to coronary computed tomography angiography (CCTA)...
  42. doi request reprint Biomarkers in relation to the effects of ticagrelor in comparison with clopidogrel in non-ST-elevation acute coronary syndrome patients managed with or without in-hospital revascularization: a substudy from the Prospective Randomized Platelet Inhibition a
    Lars Wallentin
    Department of Medical Sciences, Cardiology and Uppsala Clinical Research Center, Uppsala University, Uppsala, Sweden L W, D L, L W, C H, S K J Department of Medical Sciences, Clinical Chemistry and Uppsala Clinical Research Center Uppsala University, Uppsala, Sweden A S Division of Cardiovascular Health and Disease, Heart, Lung and Vascular Institute, Academic Health Center, Cincinnati, OH R C B Department of Medicine, Stanford University, Stanford, CA R A H, K W M TIMI Study Group, Cardiovascular Division, Brigham and Women s Hospital, Boston, MA C P C Department of Cardiology, Medisch Centrum Alkmaar, Alkmaar, Netherlands J H C AstraZeneca Research and Development, Molndal, Sweden A H Medizinische Klinik, Universitatsklinikum Heidelberg, Heidelberg, Germany E G, H A K Medical Department, Hospital Unit West, Herning Holstbro, Denmark S H INSERM Unité 698, Paris, Department of Biochemistry
    Circulation 129:293-303. 2014
    ....
  43. doi request reprint Reduction of radiation exposure and improvement of image quality with BMI-adapted prospective cardiac computed tomography and iterative reconstruction
    Waldemar Hosch
    University of Heidelberg, Department of Diagnostic and Interventional Radiology, Heidelberg, Germany
    Eur J Radiol 81:3568-76. 2012
    ....
  44. pmc Green tea halts progression of cardiac transthyretin amyloidosis: an observational report
    Arnt V Kristen
    Department of Cardiology, Angiology, and Respiratory Medicine, University Hospital Heidelberg, Im Neuenheimer Feld 410, 69120 Heidelberg, Germany
    Clin Res Cardiol 101:805-13. 2012
    ..Thus, it might also halt progression of TTR amyloidosis. This is a single-center observational report on the effects of GT consumption in patients with ATTR cardiomopathy...
  45. ncbi request reprint Cardiac troponin T at 96 hours after acute myocardial infarction correlates with infarct size and cardiac function
    Henning Steen
    Abteilung Innere Medizin III, Medizinische Klinik, Universitatsklinikum Heidelberg, Heidelberg, Germany
    J Am Coll Cardiol 48:2192-4. 2006
    ..Due to limited availability and high costs, serologic tests are frequently used as an alternative...
  46. doi request reprint Quantitative analysis of left ventricular dyssynchrony using cardiac computed tomography versus three-dimensional echocardiography
    Sebastian J Buss
    Department of Cardiology, University of Heidelberg, Im Neuenheimer Feld 410, 69120 Heidelberg, Germany
    Eur Radiol 22:1303-9. 2012
    ....
  47. doi request reprint Prevalence of different gadolinium enhancement patterns in patients after heart transplantation
    Henning Steen
    Abteilung Innere Medizin III, Medizinische Klinik, Universitatsklinikum Heidelberg, Heidelberg, Germany
    J Am Coll Cardiol 52:1160-7. 2008
    ..We hypothesized that contrast-enhanced magnetic resonance imaging (CE-MRI) detects chronic TCAD-related myocardial infarctions (MIs), even in patients with angiographically classified mild TCAD...
  48. ncbi request reprint Usefulness of real-time myocardial perfusion imaging to evaluate tissue level reperfusion in patients with non-ST-elevation myocardial infarction
    Grigorios Korosoglou
    Department of Cardiology, University of Heidelberg, Heidelberg, Germany
    Am J Cardiol 95:1033-8. 2005
    ..Improvement of regional tissue perfusion after revascularization is closely related to functional recovery. This information may aid risk stratification and allow monitoring of the effectiveness of reperfusion therapy in these patients...
  49. doi request reprint In vitro evaluation of 56 coronary artery stents by 256-slice multi-detector coronary CT
    Henning Steen
    University of Heidelberg, Department of Cardiology, Im Neuenheimer Feld 410, Heidelberg 69120, Germany
    Eur J Radiol 80:143-50. 2011
    ..We sought to investigate stent lumen visibility of 56 coronary stents with the newest 256-multi-slice-CT (256-MDCT) technology for different reconstruction algorithms in an in vitro model...
  50. pmc Myocardial late gadolinium enhancement cardiovascular magnetic resonance in patients with cirrhosis
    Dirk Lossnitzer
    Department of Internal Medicine III, University Hospital of Heidelberg, Im Neuenheimer Feld 410, 69120 Heidelberg, Germany
    J Cardiovasc Magn Reson 12:47. 2010
    ..We sought to identify myocardial tissue characterization and evaluate cardiovascular magnetic resonance (CMR) for diagnosis of cardiac impairment...
  51. doi request reprint Minor troponin T elevation in patients 6 months after acute myocardial infarction: an observational study
    Mirja Neizel
    Medical Clinic III, University Hospital Heidelberg, Heidelberg, Germany
    Clin Res Cardiol 98:297-304. 2009
    ....
  52. ncbi request reprint Absence of auto-antibodies against cardiac troponin I predicts improvement of left ventricular function after acute myocardial infarction
    Florian Leuschner
    Department of Internal Medicine III, Cardiology, University of Heidelberg, Im Neuenheimer Feld 410, 69120 Heidelberg, Germany
    Eur Heart J 29:1949-55. 2008
    ..Others have shown that auto-antibodies to cTnI are present in patients with acute coronary syndrome, but little is known about the clinical relevance of detected cTnI-Ab...
  53. doi request reprint Image quality and radiation dose in 256-slice cardiac computed tomography: comparison of prospective versus retrospective image acquisition protocols
    Waldemar Hosch
    University of Heidelberg, Department of Diagnostic and Interventional Radiology, Heidelberg, Germany
    Eur J Radiol 80:127-35. 2011
    ..To assess coronary artery image quality and patient radiation exposure in patients who underwent clinically indicated 256-slice CTA...
  54. doi request reprint Osteopontin, a new prognostic biomarker in patients with chronic heart failure
    Mark Rosenberg
    Department of Internal Medicine III, University of Heidelberg, Heidelberg, Germany
    Circ Heart Fail 1:43-9. 2008
    ..We therefore tested whether osteopontin plasma levels are elevated in patients with chronic heart failure and whether they provide independent prognostic information...
  55. pmc Steady-state equilibrium phase inversion recovery ON-resonant water suppression (IRON) MR angiography in conjunction with superparamagnetic nanoparticles. A robust technique for imaging within a wide range of contrast agent dosages
    Gitsios Gitsioudis
    University of Heidelberg, Department of Cardiology, Heidelberg, Germany
    J Magn Reson Imaging 38:836-44. 2013
    ....
  56. doi request reprint Dobutamine stress cardiac magnetic resonance versus echocardiography for the assessment of outcome in patients with suspected or known coronary artery disease. Are the two imaging modalities comparable?
    Eleni Bikiri
    University of Heidelberg, Department of Cardiology, Heidelberg, Germany
    Int J Cardiol 171:153-60. 2014
    ..To compare the value of Dobutamine stress echocardiography (DSE) with that provided by Dobutamine Cardiac Magnetic Resonance (DCMR) for the non-invasive risk stratification of patients with suspected or known coronary artery disease (CAD)...
  57. doi request reprint Absolute and relative kinetic changes of high-sensitivity cardiac troponin T in acute coronary syndrome and in patients with increased troponin in the absence of acute coronary syndrome
    Matthias Mueller
    Department of Internal Medicine III, Cardiology, University Hospital Heidelberg, Heidelberg, Germany
    Clin Chem 58:209-18. 2012
    ....
  58. doi request reprint Contrast-enhanced magnetic resonance imaging reveals early decrease of transmural extent of reperfused acute myocardial infarction
    Constanze Merten
    Abteilung Innere Medizin III, Medizinische Klinik, Universitatsklinikum Heidelberg, 69120, Heidelberg, Germany
    Clin Res Cardiol 97:913-6. 2008
    ..We conclude that the transmural infarct extent is not stable over the first days after STEMI which should be taken into account when assessing viability in clinical and research settings...
  59. ncbi request reprint Quantitative evaluation of myocardial blush to assess tissue level reperfusion in patients with acute ST-elevation myocardial infarction: incremental prognostic value compared with visual assessment
    Grigorios Korosoglou
    Department of Cardiology, University of Heidelberg, Heidelberg, Germany
    Am Heart J 153:612-20. 2007
    ..The purpose of the study was to test whether quantification of MBG can enhance the predictive value of visual assessment for functional recovery in patients with acute ST-elevation myocardial infarction (STEMI)...
  60. doi request reprint Soluble TWEAK is markedly upregulated in patients with ST-elevation myocardial infarction and related to an adverse short-term outcome
    Emmanuel Chorianopoulos
    Department of Cardiology, Angiology and Pulmology, Heidelberg University Hospital, Im Neuenheimer Feld 410, 69120 Heidelberg, Germany
    Atherosclerosis 211:322-6. 2010
    ..In this retrospective pilot study we thus sought to evaluate serum levels of soluble TWEAK (sTWEAK) patients with acute ST-elevation myocardial infarction (STEMI)...
  61. ncbi request reprint Cardiac biomarkers in haemodialysis patients: the prognostic value of amino-terminal pro-B-type natriuretic peptide and cardiac troponin T
    Claudia Sommerer
    Department of Nephrology, University Hospital of Heidelberg, Heidelberg, Germany
    Nephron Clin Pract 107:c77-81. 2007
    ..They provide a useful rationale for the screening of occult cardiac disease and optimization of the dialysis procedure with respect to volume control...
  62. doi request reprint Troponins and high-sensitivity troponins as markers of necrosis in CAD and heart failure
    Evangelos Giannitsis
    Department of Internal Medicine III, University Hospital Heidelberg, Heidelberg, Germany
    Herz 34:600-6. 2009
    ..The causes of these elevations may be due to acute, subacute and chronic cardiac disease such as heart failure or cardiomyopathies...
  63. pmc Hepatic and renal failure after anterior myocardial infarction induced apical ventricular septal defect
    Dirk Lossnitzer
    Division of Cardiology, Pneumology and Angiology, Department of Internal Medicine III, University of Heidelberg, 69120 Heidelberg, Germany
    Case Report Med 2010:645236. 2010
    ..To our knowledge, for the first time we report successful CAPD catheter drainage of hydroperitoneum in combination with CAPD hemodialysis...
  64. pmc Diagnostic performance of rising, falling, or rising and falling kinetic changes of high-sensitivity cardiac troponin T in an unselected emergency department population
    Moritz Biener
    University Hospital Heidelberg, Heidelberg, Germany
    Eur Heart J Acute Cardiovasc Care 2:314-22. 2013
    ..However, whether rising or falling patterns of high-sensitivity cardiac troponin T (hs-cTnT) improve the discrimination of ST-elevation myocardial infarction (non-STEMI) from non-acute coronary syndromes (ACS) has not been evaluated yet...
  65. pmc HMGB1 is associated with atherosclerotic plaque composition and burden in patients with stable coronary artery disease
    Martin Andrassy
    Department of Cardiology, University of Heidelberg, Heidelberg, Germany
    PLoS ONE 7:e52081. 2012
    ..In this study, we sought to investigate the association of plasma HMGB1 with coronary plaque composition in patients with suspected or known coronary artery disease (CAD)...
  66. doi request reprint Biological variation and reference change value of high-sensitivity troponin T in healthy individuals during short and intermediate follow-up periods
    Lutz Frankenstein
    Department of Cardiology, Angiology, Pulmonology, University of Heidelberg, Heidelberg, Germany
    Clin Chem 57:1068-71. 2011
    ....
  67. doi request reprint Elevated myocardial enzymes and natriuretic peptides in anorexia nervosa: prototypic condition for the pathophysiology of cachexia?
    Arne Zastrow
    Department of General Internal Medicine and Psychosomatics, University of Heidelberg, Heidelberg, Germany
    Cardiology 118:256-9. 2011
    ..A review of the available literature is provided. Further research is required to explain the pathophysiological meaning of the abnormal laboratory findings...
  68. ncbi request reprint Images in cardiovascular medicine. A rare form of midventricular Tako-Tsubo after emotional stress followed up with magnetic resonance imaging
    Henning Steen
    Division of Cardiology, Pneumology, and Angiology, Department of Internal Medicine III, University of Heidelberg, Im Neuenheimer Feld 410, 69120 Heidelberg, Germany
    Circulation 114:e248. 2006
  69. pmc Anomalous origin of the left circumflex coronary artery from the pulmonary artery. A very rare congenital anomaly in an adult patient diagnosed by cardiovascular magnetic resonance
    Grigorios Korosoglou
    Department of Cardiology, University of Heidelberg, Heidelberg, Germany
    J Cardiovasc Magn Reson 10:4. 2008
    ..CMR provided the unambiguous depiction of the origin of the anomalous LCX from the right pulmonary artery and the delineation of its proximal course in this case of a very rare coronary anomaly in adults...
  70. doi request reprint Combined testing of high-sensitivity troponin T and copeptin on presentation at prespecified cutoffs improves rapid rule-out of non-ST-segment elevation myocardial infarction
    Evangelos Giannitsis
    Medizinische Klinik, Abteilung für Innere Medizin III, Universitatsklinikum Heidelberg, Heidelberg, Germany
    Clin Chem 57:1452-5. 2011
    ....
  71. doi request reprint Highly sensitive cardiac troponin T values remain constant after brief exercise- or pharmacologic-induced reversible myocardial ischemia
    Kerstin Kurz
    Department of Medicine III, University of Heidelberg, Im Neuenheimer Feld 410, Heidelberg, Germany
    Clin Chem 54:1234-8. 2008
    ..Using a new precommercial high-sensitivity cardiac troponin T (hsTnT) assay, we evaluated whether hsTnT increases after reversible myocardial ischemia...
  72. ncbi request reprint Rationale for testing the cardiovascular risk for patients with COX-2 inhibitors on the basis of biomarker NT-proBNP
    Evangelos Giannitsis
    Department of Internal Medicine III Cardiology, Medical Clinic, Heidelberg University Hospital, Heidelberg, Germany
    Clin Lab 51:63-83. 2005
    ..Follow-up with NT-proBNP (monitoring) can be helpful in detecting imminent cardiac decompensation at an earlier stage in order to take suitable countermeasures...
  73. ncbi request reprint Cardiospecificity of the 3rd generation cardiac troponin T assay during and after a 216 km ultra-endurance marathon run in Death Valley
    H J Roth
    Laboratory Dr Limbach and Colleagues, Heidelberg, Germany
    Clin Res Cardiol 96:359-64. 2007
    ..The aim of the present study was to evaluate the cardiospecificity of the 3(rd) generation cardiac cTnT assay during and after an ultra-endurance race of 216 km at extreme environmental conditions in Death Valley...
  74. ncbi request reprint High-sensitive troponin T: a novel biomarker for prognosis and disease severity in patients with pulmonary arterial hypertension
    Arthur Filusch
    Department of Cardiology, Angiology and Respiratory Medicine, University Medical Center, Im Neuenheimer Feld 410, D 69120 Heidelberg, Germany
    Clin Sci (Lond) 119:207-13. 2010
    ..In conclusion, in PAH patients, the novel biomarker hsTnT is associated with death and advanced WHO functional class, and is related to systolic right ventricular dysfunction and an impaired 6-min walk distance...
  75. doi request reprint Assessment of disease severity and outcome in patients with systemic light-chain amyloidosis by the high-sensitivity troponin T assay
    Arnt V Kristen
    Department of Cardiology, Angiology, and Respiratory Medicine, Heidelberg University, Heidelberg, Germany
    Blood 116:2455-61. 2010
    ..Plasma levels of the hs-TnT assay are associated with the clinical, morphologic, and functional severity of cardiac AL amyloidosis and could provide useful information for clinicians on cardiac involvement and outcome...
  76. ncbi request reprint [Diagnosis of ischemia]
    Kerstin Kurz
    Abteilung Innere Medizin III, Medizinische Klinik, Universitatsklinikum, Heidelberg
    Herz 29:575-81. 2004
    ..Consecutively, patients without high-risk features need a thorough noninvasive evaluation for the presence of significant CAD which is comparable to patients presenting with chronic stable angina pectoris...
  77. ncbi request reprint Visualization of a coronary fistula with pulmonary drainage
    Henning Steen
    Division of Cardiology, Pneumology and Angiology, Department of Internal Medicine III, University of Heidelberg, Im Neuenheimer Feld 410, 69120, Heidelberg, Germany
    Clin Res Cardiol 95:355-6. 2006
  78. doi request reprint Beta2-integrin activation on T cell subsets is an independent prognostic factor in unstable angina pectoris
    Mathias H Konstandin
    Dept of Cardiology, Ruprecht Karls University, Heidelberg, Germany
    Basic Res Cardiol 104:341-51. 2009
    ..Beta2-integrin mediated T cell recruitment plays a pivotal role in coronary atherosclerotic plaque rupture. The present study investigates beta2-integrin activation on T cell subsets as a risk marker in UA...
  79. ncbi request reprint Determination of clopidogrel resistance by whole blood platelet aggregometry and inhibitors of the P2Y12 receptor
    Boris T Ivandic
    Department of Medicine III, University of Heidelberg, Heidelberg, Germany
    Clin Chem 52:383-8. 2006
    ..Inhibition of platelet aggregation by clopidogrel may be insufficient in up to 30% of users. These nonresponders carry an increased risk of cardiovascular events. We reported here a simple assay to study clopidogrel responsiveness...
  80. ncbi request reprint Aortic intramural hematoma in a 17-year-old patient with dysphagia
    Raffi Bekeredjian
    Department of Cardiology, University of Heidelberg, Heidelberg, Germany
    Clin Cardiol 29:373. 2006
  81. ncbi request reprint Anomalous right coronary artery arising next to the left coronary ostium Unambiguous detection of the anatomy by computed tomography and evaluation of functional significance by cardiovascular magnetic resonance
    Grigorios Korosoglou
    Department of Cardiology, University of Heidelberg, Heidelberg, Germany
    Int J Cardiol 145:e50-3. 2010
    ..CMR during adenosine infusion ruled-out inducible ischemia, yielding normal perfusion patterns both in the RCA and in the LAD coronary territory. Since ischemia was not demonstrated by stress CMR, revascularization was not performed...
  82. ncbi request reprint Comparison of cardiac troponin T and troponin I assays--implications of analytical and biochemical differences on clinical performance
    Evangelos Giannitsis
    Abteilung Innere Medizin III, Medizinische Klinik und Poliklinik, Universitatsklinikum Heidelberg
    Clin Lab 50:521-8. 2004
    ..The present review will provide a state-of-the-art overview on the performance of cardiac troponins in acute coronary disease and other clinical conditions...
  83. ncbi request reprint Large-scale mutation screening in patients with dilated or hypertrophic cardiomyopathy: a pilot study using DGGE
    Raphael Zeller
    Innere Medizin III, Universitatsklinikum Heidelberg, Im Neuenheimer Feld 410, 69120 Heidelberg, Germany
    J Mol Med (Berl) 84:682-91. 2006
    ..The platform proved a valuable contribution to elucidating the genetic causes of DCM and HCM as demonstrated by the identification of 17 different known and novel mutations and 98 different polymorphisms in our setting...
  84. ncbi request reprint Usefulness of real-time myocardial perfusion imaging in the evaluation of patients with first time chest pain
    Grigorios Korosoglou
    Department of Cardiology, University of Heidelberg, Heidelberg, Germany
    Am J Cardiol 94:1225-31. 2004
    ..73, p <0.001) and with ejection fraction at 4 weeks of follow-up (r = -0.79, p <0.001). Thus, our data suggest that MCE can accurately identify patients who have ACS...
  85. doi request reprint N-terminal pro-B-type natriuretic peptide concentrations predict the risk of cardiovascular adverse events from antiinflammatory drugs: a pilot trial
    Kay Brune
    Department of Experimental and Clinical Pharmacology and Toxicology, Friedrich Alexander University of Erlangen Nuremberg, Erlangen, Germany
    Clin Chem 54:1149-57. 2008
    ..we investigated whether higher concentrations of N-terminal pro-B-type natriuretic peptide (NT-proBNP) predicts cardiovascular adverse events (CV-AEs) in patients with osteoarthritis treated with antiinflammatory drugs...
  86. ncbi request reprint Prehospital initiation of tirofiban in patients with ST-elevation myocardial infarction undergoing primary angioplasty (On-TIME 2): a multicentre, double-blind, randomised controlled trial
    Arnoud W J Van't Hof
    Isala Klinieken, Department of Cardiology, Zwolle, Netherlands
    Lancet 372:537-46. 2008
    ..We investigated whether the results of primary coronary angioplasty (PCI) can be improved by the early administration of the glycoprotein IIb/IIIa blocker tirofiban at first medical contact in the ambulance or referral centre...
  87. ncbi request reprint Time-dependent changes of hs-CRP serum concentration in patients with non-ST elevation acute coronary syndrome
    Jürgen Jahn
    Department of Internal Medicine, Borromäus Hospital, Leer, Germany
    Herz 29:795-801. 2004
    ..Therefore, it is interesting to discuss the value of follow-up measurements of hs-CRP in patients with coronary artery disease (CAD)...
  88. ncbi request reprint Still unresolved issues with brain-type natriuretic peptide measurement in the critically ill patient
    Evangelos Giannitsis
    Crit Care Med 31:2703-4. 2003
  89. ncbi request reprint The effects of facilitated primary PCI by guide wire on procedural and clinical outcomes in acute ST-segment elevation myocardial infarction
    Volkhard Kurowski
    Medizinische Klinik II, Medizinische Universitat zu Lubeck, Ratzeburger Allee 160, 23538, Lubeck, Germany
    Clin Res Cardiol 96:557-65. 2007
    ....
  90. pmc N-terminal prohormone brain natriuretic peptide: a biomarker for detecting cardiovascular risks in patients with rheumatoid arthritis or osteoarthritis?
    Thomas Häupl
    Ann Rheum Dis 66:838-9. 2007
  91. ncbi request reprint [Indicators of plaque stability]
    Henning Steen
    Medizinische Klinik II, Medizinische Universitat zu Lubeck
    Herz 27:64-7. 2002
  92. ncbi request reprint Temporal repolarization inhomogeneity and reperfusion arrhythmias in patients undergoing successful primary percutaneous coronary intervention for acute ST-segment elevation myocardial infarction: impact of admission troponin T
    Hendrik Bonnemeier
    Medizinische Klinik II, Medizinische Universitat zu Lubeck, Lubeck, Germany
    Am Heart J 145:484-92. 2003
    ....
  93. ncbi request reprint Cardiac troponin elevations in patients without acute coronary syndrome
    Christian W Hamm
    Circulation 106:2871-2. 2002
  94. ncbi request reprint Prognostic significance of admission cardiac troponin T in patients treated successfully with direct percutaneous interventions for acute ST-segment elevation myocardial infarction
    Volkhard Kurowski
    Medizinische Klinik II, Medizinische Universitat zu Lubeck, Germany
    Crit Care Med 30:2229-35. 2002
    ..Cardiac troponin T (cTnT) elevations at admission indicate a high-risk subgroup of patients with acute ST-segment elevation myocardial infarction, possibly due to a higher failure rate of reperfusion therapies...
  95. ncbi request reprint Determination of aspirin responsiveness by use of whole blood platelet aggregometry
    Boris T Ivandic
    Department of Medicine III, University of Heidelberg, Germany
    Clin Chem 53:614-9. 2007
    ..Insufficient platelet inhibition is associated with an increased cardiovascular risk in up to 30% of patients taking regular doses of aspirin. We describe an assay to study aspirin responsiveness...
  96. ncbi request reprint Very early cardiac magnetic resonance imaging for quantification of myocardial tissue perfusion in patients receiving tirofiban before percutaneous coronary intervention for ST-elevation myocardial infarction
    Henning Steen
    Department of Medicine, Division of Cardiology, Johns Hopkins Medical Institutions, Baltimore, MD, USA
    Am Heart J 149:564. 2005
    ..Magnetic resonance imaging is a novel noninvasive method providing complementary information on myocardial blood flow and cardiac function...
  97. ncbi request reprint Troponin T release in hemodialysis patients
    Evangelos Giannitsis
    Circulation 110:e25-6; author reply e25-6. 2004
  98. ncbi request reprint Admission troponin T, advanced age and male gender identify patients with improved myocardial tissue perfusion after abciximab administration for ST-segment elevation myocardial infarction
    Stephanie Lehrke
    Medizinische Universitätsklinik Heidelberg Innere III, Department of Cardiology, Bergheimer Strasse 58, 69115 Heidelberg, Germany
    Thromb Haemost 92:1214-20. 2004
    ..1 microg/L on admission, age over 70 years and male gender...
  99. ncbi request reprint Cardiac biomarkers for detection of myocardial infarction: perspectives from past to present
    Sidney B Rosalki
    10 Wimpole News, London, United Kingdom
    Clin Chem 50:2205-13. 2004
    ....
  100. ncbi request reprint Cardiac troponin T for prediction of short- and long-term morbidity and mortality after elective open heart surgery
    Stephanie Lehrke
    Johns Hopkins University, Department of Cardiology, Baltimore, MD, USA
    Clin Chem 50:1560-7. 2004
    ..We sought to determine the optimum time point for blood sampling and the respective cutoff value of cardiac troponin T (cTnT) for risk assessment in patients undergoing cardiac surgery...
  101. ncbi request reprint Release kinetics of cardiac troponin T in survivors of confirmed severe pulmonary embolism
    Margit Müller-Bardorff
    Universitatsklinikum Lubeck, Medizinische Klinik II, Ratzeburger Allee 160, 23538 Lubeck, Germany
    Clin Chem 48:673-5. 2002