Research Topics
| Markus GastparSummaryAffiliation: University of Essen Country: Germany Publications
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Detail Information
Publications
Lack of efficacy of naltrexone in the prevention of alcohol relapse: results from a German multicenter studyMarkus Gastpar
Department of Psychiatry of the University of Essen, Germany
J Clin Psychopharmacol 22:592-8. 2002..Nevertheless, the question arises whether self-reports of drinking are more reliable than gamma-GT as a measure of recent alcohol consumption...
Antipsychotic treatment of psychosis associated with multiple sclerosisEugen Davids
Department of Psychiatry and Psychotherapy, University of Duisburg Essen, Virchowstr 174, 45147, Germany
Prog Neuropsychopharmacol Biol Psychiatry 28:743-4. 2004..Risperidone was not administered with respect to possible EPS. However, ziprasidone was tolerated well and appeared to be effective...
Age-related changes of the dentate nuclei in normal adults as revealed by 3D fast low angle shot (FLASH) echo sequence magnetic resonance imagingMatthias Maschke
Department of Neurology, University of Duisburg Essen, Hufelandstr 55, 45122 Essen, Germany
J Neurol 251:740-6. 2004..These age-dependent changes have to be taken into account in interpretation of disease related MR changes of cerebellar nuclei in patients with degenerative or acquired cerebellar ataxia...
History of attention-deficit hyperactivity disorder symptoms and opioid dependence: a controlled studyEugen Davids
Department of Psychiatry and Psychotherapy, University of Duisburg Essen, Rhine Clinics Essen, Virchowstr 174, 45147 Essen, Germany
Prog Neuropsychopharmacol Biol Psychiatry 29:291-6. 2005..Patients with ADHD history seemed to experience a drug abuse career with more complications which need to be recognized with focused attention in order to start earlier treatment strategies...
Vermal atrophy of alcoholics correlate with serum thiamine levels but not with dentate iron concentrations as estimated by MRIMatthias Maschke
Department of Neurology, University Duisburg Essen, Hufelandstr 55, 45122 Essen, Germany
J Neurol 252:704-11. 2005..344, p = 0.028). These results support the view that thiamine deficiency rather than direct neurotoxic effects of alcohol is the main causative factor for the development of alcoholic cerebellar degeneration...
Sympathetic neural activation evoked by mu-receptor blockade in patients addicted to opioids is abolished by intravenous clonidinePeter Kienbaum
Abteilung für Anästhesiologie und Intensivmedizin, Universitatsklinikum, Essen, Germany
Anesthesiology 96:346-51. 2002....
Attention deficit hyperactivity disorder and borderline personality disorderEugen Davids
Department of Psychiatry and Psychotherapy, University of Duisburg Essen Rhine Clinics Essen Virchowstrasse 174, 45147 Essen, Germany
Prog Neuropsychopharmacol Biol Psychiatry 29:865-77. 2005..From a neuropsychological point of view dissociation in BPD might be regarded as a special form of behavioral inhibition and sustained attention comparable to ADHD. Possible therapeutic strategies of comorbid ADHD and BPD are discussed...
A pilot clinical trial of oxcarbazepine in adults with attention-deficit hyperactivity disorderEugen Davids
Department of Psychiatry and Psychotherapy, Rhine Clinics Essen, University of Duisburg Essen, Virchowstr 174, 45147 Essen, Germany
Prog Neuropsychopharmacol Biol Psychiatry 30:1033-8. 2006..The results of this investigation indicate that oxcarbazepine may be a potentially useful agent for the treatment of ADHD in adults. However, placebo-controlled randomized trials are needed to provide evidence...
Psychotropic drug prescription in a psychiatric university hospital in GermanyEugen Davids
Department of Psychiatry and Psychotherapy, Rhine Clinics Essen, University of Duisburg Essen, Virchowstr 174, 45147 Essen, Germany
Prog Neuropsychopharmacol Biol Psychiatry 30:1109-16. 2006..Such surveys should be carried out more frequently and simultaneously in different centers. Critical comparisons could help to optimize treatment...
Neuropsychological assessment of adult patients with attention-deficit/hyperactivity disorderBernhard W Müller
Clinic for Psychiatry and Psychotherapy, University of Duisburg Essen, Virchowstrasse 174, 45147 Essen, Germany
Eur Arch Psychiatry Clin Neurosci 257:112-9. 2007..Adults with ADHD show indicators of lowered cognitive performance under medication. These are related more to memory and attention under high mental load than to response inhibition or simple attention or motor performance...
The intensity dependence of auditory ERP components in unmedicated patients with major depression and healthy controls. An analysis of group differencesThomas Linka
Clinic for Psychiatry and Psychotherapy, Rheinische Kliniken Essen, University of Duisburg Essen, 45147 Essen, Germany
J Affect Disord 103:139-45. 2007..Therefore, the purpose of the present study was to compare the IDAP in unmedicated depressed patients with that of healthy control subjects...
[Escitalopram: a chiral agent for treatment of depression]Michael Overlack
, Rheinische Kliniken Essen
Med Monatsschr Pharm 27:148-51. 2004
[Acute treatment of opiate addiction in patients in 2001]Markus Gastpar
Klinik fur Psychiatrie und Psychotherapie der Rheinischen Kliniken Essen
Z Arztl Fortbild Qualitatssich 96:301-6. 2002..Readers are invited to comment prior to the publication of the definitive text of the guidelines...
[Attention-deficit/hyperactivity disorder and substance abuse]Eugen Davids
Rheinische Kliniken Essen, Klinik für Psychiatrie und Psychotherapie der Universität Duisburg Essen
Psychiatr Prax 30:182-6. 2003..Possible pharmacological and non-pharmacological therapeutic strategies in patients with ADHD and substance abuse are discussed...
[Descriptive analysis of drug-related deaths over a 5-year period]Eugen Davids
Klinik für Psychiatrie und Psychotherapie der Universität Essen, Rheinische Kliniken Essen
Psychiatr Prax 30:266-71. 2003..The purpose of the study was to examine opiate-related deaths in the German town Essen (inhabitants about 600,000) from 1990-1994. Sociodemographic data, psychiatric comorbidity and purity of the used opioids were of focussed interest...
Treatment of acute alcohol withdrawal with gabapentin: results from a controlled two-center trialUdo Bonnet
Department of Psychiatry and Psychotherapy, University of Essen, Essen, Germany
J Clin Psychopharmacol 23:514-9. 2003..The combination of GP and CLO was safe...
Safety and efficacy of combined clozapine-lithium pharmacotherapyStefan Bender
Department of Psychiatry and Psychotherapy, The University of Duisburg Essen, Essen, Germany
Int J Neuropsychopharmacol 7:59-63. 2004....
Buprenorphine in the treatment of opioid dependenceEugen Davids
Rhine Clinics Essen, Department of Psychiatry and Psychotherapy, University of Duisburg Essen, Virchowstr 174, 45147 Essen, Germany
Eur Neuropsychopharmacol 14:209-16. 2004..Buprenorphine is an additional treatment option for heroin dependent patients, especially for those who do not wish to start or continue with methadone or for those who do not seem to benefit from adequate dosages of methadone...
Depression during an acute episode of schizophrenia or schizophreniform disorder and its impact on treatment responseMarkus Jager
Department of Psychiatry, Ludwig Maximilians University, Munich, Germany
Psychiatry Res 158:297-305. 2008..Therefore, the hypothesis that depressive symptoms are predictive of a favorable treatment response was not supported by the present study...
World Federation of Societies of Biological Psychiatry (WFSBP) Guidelines for Biological Treatment of Substance Use and Related Disorders, Part 1: AlcoholismMichael Soyka
Psychiatric Hospital Meiringen, Meiringen, Switzerland
World J Biol Psychiatry 9:6-23. 2008..This first part of the guidelines covers the treatment of alcohol dependence; Part 2 will be devoted to the treatment of drug dependence...
[Sex-specific characteristics of mental disorders. Women are different]Markus Gastpar
Fliedner Klinik Berlin, , Berlin
MMW Fortschr Med 149:24-5. 2007
Changes in the treatment of acute psychosis in a German public hospital from 1998 to 2004Tiemo Wessels
Rhine Clinics Essen, Department of Psychiatry and Psychotherapy, University of Duisburg Essen, Virchowstr 174, Essen 45147, Germany
Psychiatr Q 78:91-9. 2007..The aim of our study was to investigate antipsychotic treatment strategies in acute schizophrenic episodes in a German university hospital...
The efficacy of the dopamine D2/D3 antagonist tiapride in maintaining abstinence: a randomized, double-blind, placebo-controlled trial in 299 alcohol-dependent patientsStefan Bender
Department of Psychiatry and Psychotherapy, Rhine State Hospital, University Hospital Essen, Germany
Int J Neuropsychopharmacol 10:653-60. 2007..Regarding the high success rate in the placebo group the influence of psychosocial treatment in studies investigating drug effects on the course of alcohol dependence has to be considered...
Psychopathological characteristics and treatment response of first episode compared with multiple episode schizophrenic disordersMarkus Jager
Department of Psychiatry, Ludwig Maximilians University, Nussbaumstr 7, D 80336 Munich, Germany
Eur Arch Psychiatry Clin Neurosci 257:47-53. 2007..The aim was to investigate the hypothesis that patients with first episode schizophrenic disorders have a more favorable treatment response than those with multiple episodes...
[The visit at home by a social worker of a psychiatric outpatient clinic]Markus Banger
Rheinische Kliniken Bonn
Psychiatr Prax 31:198-202. 2004....
Chronic mu-opioid receptor stimulation alters cardiovascular regulation in humans: differential effects on muscle sympathetic and heart rate responses to arterial hypotensionPeter Kienbaum
, , Germany
J Cardiovasc Pharmacol 40:363-9. 2002....
Buprenorphine and methadone in the treatment of opioid dependence: methods and design of the COBRA studyHans Ulrich Wittchen
Institut für Klinische Psychologie und Psychotherapie, TU Dresden, Germany
Int J Methods Psychiatr Res 14:14-28. 2005..The COBRA study provides a unique comprehensive database, informing about the natural allocation and intervention processes in routine care and about the course and outcome of patients treated with buprenorphine or methadone...
Partial response and nonresponse to antidepressant therapy: current approaches and treatment optionsRobert M A Hirschfeld
Department of Psychiatry and Behavioral Sciences, University of Texas Medical Branch, Galveston 77555 0188, USA
J Clin Psychiatry 63:826-37. 2002..Switching to an agent of a different class is probably optimal for those patients who fail to respond to first-line therapy...
Feasibility and outcome of substitution treatment of heroin-dependent patients in specialized substitution centers and primary care facilities in Germany: a naturalistic study in 2694 patientsHans Ulrich Wittchen
Institute of Clinical Psychology and Psychotherapy, Technische Universitaet Dresden, Chemnitzerstrasse 46, 01187 Dresden, Germany
Drug Alcohol Depend 95:245-57. 2008..Despite many short-term studies, little is known about the long-term (12-month) effects of these treatments in different settings, i.e. primary care-based (PMC) and specialized substitution centers (SSCs)...
Syphilis infection among drug addicts in western GermanyNorbert Scherbaum
Addiction 97:601-2. 2002
Concomitant endocrine and immune alterations during alcohol intoxication and acute withdrawal in alcohol-dependent subjectsSven Kutscher
Clinic for Psychiatry and Psychotherapy, University of Essen, Essen, Germany
Neuropsychobiology 45:144-9. 2002..However, resolution of acute alcohol withdrawal is associated with a return of plasma cortisol to control levels, and a concomitant increase in peripheral blood monocyte numbers...
Urine labeling with orally applied marker substances in drug substitution therapyBernd Huppertz
, Zentrallabor, Cologne, Germany
Clin Chem Lab Med 42:621-6. 2004..Normal values for marker substances in urine were determined. The results suggest that this labeling procedure is a new diagnostic tool to prevent manipulation of urine samples by drug addicts receiving substitution therapy...
