Markus Gastpar

Summary

Affiliation: University of Essen
Country: Germany

Publications

  1. ncbi request reprint [Acute treatment of opiate addiction in patients in 2001]
    Markus Gastpar
    Klinik fur Psychiatrie und Psychotherapie der Rheinischen Kliniken Essen
    Z Arztl Fortbild Qualitatssich 96:301-6. 2002
  2. ncbi request reprint Efficacy and tolerability of hypericum extract STW3 in long-term treatment with a once-daily dosage in comparison with sertraline
    M Gastpar
    General Psychiatric Hospital, Dept of Psychiatry and Psychotherapy, University of Essen, Germany
    Pharmacopsychiatry 38:78-86. 2005
  3. ncbi request reprint Treatment of anxiety, tension and restlessness states with Kava special extract WS 1490 in general practice: a randomized placebo-controlled double-blind multicenter trial
    M Gastpar
    Klinik fur Psychiatrie und Psychotherapie, Rheinische Kliniken, Essen, Germany
    Phytomedicine 10:631-9. 2003
  4. ncbi request reprint Sustained improvement of clinical outcome with risperidone long-acting injectable in psychotic patients previously treated with olanzapine
    M Gastpar
    Department of Psychiatry, University of Essen, Essen, Germany
    J Psychopharmacol 19:32-8. 2005
  5. ncbi request reprint Comparative efficacy and safety of a once-daily dosage of hypericum extract STW3-VI and citalopram in patients with moderate depression: a double-blind, randomised, multicentre, placebo-controlled study
    M Gastpar
    General Psychiatric Hospital, Department of Psychiatry and Psychotherapy, University of Essen, Essen, Germany
    Pharmacopsychiatry 39:66-75. 2006
  6. doi request reprint Depression during an acute episode of schizophrenia or schizophreniform disorder and its impact on treatment response
    Markus Jager
    Department of Psychiatry, Ludwig Maximilians University, Munich, Germany
    Psychiatry Res 158:297-305. 2008
  7. doi request reprint Remission and recovery and their predictors in schizophrenia spectrum disorder: results from a 1-year follow-up naturalistic trial
    Rebecca Schennach
    Department of Psychiatry and Psychotherapy, Ludwig Maximilians University Munich, Nussbaumstrasse 7, 80336, Munich, Germany
    Psychiatr Q 83:187-207. 2012
  8. ncbi request reprint Prediction of symptom remission in schizophrenia during inpatient treatment
    Markus Jager
    Department of Psychiatry, Ludwig Maximilians University, Munich, Germany
    World J Biol Psychiatry 10:426-34. 2009
  9. doi request reprint Quality of life and subjective well-being in schizophrenia and schizophrenia spectrum disorders: valid predictors of symptomatic response and remission?
    Rebecca Schennach-Wolff
    Department of Psychiatry and Psychotherapy, Ludwig Maximilians University, Munich, Germany
    World J Biol Psychiatry 11:729-38. 2010
  10. doi request reprint Response trajectories in "real-world" naturalistically treated schizophrenia patients
    Rebecca Schennach
    Department of Psychiatry and Psychotherapy, Ludwig Maximilians University, Munich, Germany
    Schizophr Res 139:218-24. 2012

Collaborators

Detail Information

Publications76

  1. ncbi request reprint [Acute treatment of opiate addiction in patients in 2001]
    Markus Gastpar
    Klinik fur Psychiatrie und Psychotherapie der Rheinischen Kliniken Essen
    Z Arztl Fortbild Qualitatssich 96:301-6. 2002
    ..Readers are invited to comment prior to the publication of the definitive text of the guidelines...
  2. ncbi request reprint Efficacy and tolerability of hypericum extract STW3 in long-term treatment with a once-daily dosage in comparison with sertraline
    M Gastpar
    General Psychiatric Hospital, Dept of Psychiatry and Psychotherapy, University of Essen, Germany
    Pharmacopsychiatry 38:78-86. 2005
    ..The objective of this double-blind, multi-center clinical study was to demonstrate the non-inferiority of hypericum extract versus sertraline in the treatment of moderate depression...
  3. ncbi request reprint Treatment of anxiety, tension and restlessness states with Kava special extract WS 1490 in general practice: a randomized placebo-controlled double-blind multicenter trial
    M Gastpar
    Klinik fur Psychiatrie und Psychotherapie, Rheinische Kliniken, Essen, Germany
    Phytomedicine 10:631-9. 2003
    ..WS 1490 was well tolerated, with no influence on liver function tests and only one trivial adverse event (tiredness) attributable to the study drug...
  4. ncbi request reprint Sustained improvement of clinical outcome with risperidone long-acting injectable in psychotic patients previously treated with olanzapine
    M Gastpar
    Department of Psychiatry, University of Essen, Essen, Germany
    J Psychopharmacol 19:32-8. 2005
    ..The combination of improved efficacy and good tolerability may have important implications for patient adherence to therapy and subsequent long-term outcomes...
  5. ncbi request reprint Comparative efficacy and safety of a once-daily dosage of hypericum extract STW3-VI and citalopram in patients with moderate depression: a double-blind, randomised, multicentre, placebo-controlled study
    M Gastpar
    General Psychiatric Hospital, Department of Psychiatry and Psychotherapy, University of Essen, Essen, Germany
    Pharmacopsychiatry 39:66-75. 2006
    ..The primary objective of this 3-arm design study was to demonstrate the non-inferiority of hypericum extract STW3-VI (900 mg) to the SSRI citalopram (20 mg) and superiority of hypericum over placebo...
  6. doi request reprint Depression during an acute episode of schizophrenia or schizophreniform disorder and its impact on treatment response
    Markus Jager
    Department of Psychiatry, Ludwig Maximilians University, Munich, Germany
    Psychiatry Res 158:297-305. 2008
    ..Therefore, the hypothesis that depressive symptoms are predictive of a favorable treatment response was not supported by the present study...
  7. doi request reprint Remission and recovery and their predictors in schizophrenia spectrum disorder: results from a 1-year follow-up naturalistic trial
    Rebecca Schennach
    Department of Psychiatry and Psychotherapy, Ludwig Maximilians University Munich, Nussbaumstrasse 7, 80336, Munich, Germany
    Psychiatr Q 83:187-207. 2012
    ..0113) were found to be significantly predictive of recovery. Our results underline the need to implement more specific treatment strategies to improve long-term outcome...
  8. ncbi request reprint Prediction of symptom remission in schizophrenia during inpatient treatment
    Markus Jager
    Department of Psychiatry, Ludwig Maximilians University, Munich, Germany
    World J Biol Psychiatry 10:426-34. 2009
    ..The present study applied the symptom-severity component of these criteria to a sample of inpatients in order to determine the rates of remission during inpatient treatment and to explore predictors of remission...
  9. doi request reprint Quality of life and subjective well-being in schizophrenia and schizophrenia spectrum disorders: valid predictors of symptomatic response and remission?
    Rebecca Schennach-Wolff
    Department of Psychiatry and Psychotherapy, Ludwig Maximilians University, Munich, Germany
    World J Biol Psychiatry 11:729-38. 2010
    ..To examine quality of life and subjective well-being as predictors of symptomatic treatment outcome...
  10. doi request reprint Response trajectories in "real-world" naturalistically treated schizophrenia patients
    Rebecca Schennach
    Department of Psychiatry and Psychotherapy, Ludwig Maximilians University, Munich, Germany
    Schizophr Res 139:218-24. 2012
    ..To date, research has identified distinct antipsychotic response trajectories yet focussing on data from randomized-controlled trials (RCTs). Therefore, the heterogeneity of response in "real-world" schizophrenia patients is still unknown...
  11. doi request reprint Predictors of relapse in the year after hospital discharge among patients with schizophrenia
    Rebecca Schennach
    Department of Psychiatry and Psychotherapy, Ludwig Maximilians University, Nussbaumstreet 7, 80336 Munich, Germany
    Psychiatr Serv 63:87-90. 2012
    ..Relapse and its predictors were examined among patients with schizophrenia in the year after hospital discharge...
  12. doi request reprint Depressive symptoms and their association with acute treatment outcome in first-episode schizophrenia patients: comparing treatment with risperidone and haloperidol
    Michael Riedel
    Department of Psychiatry and Psychotherapy, Ludwig Maximilians University, Munich, Germany
    World J Biol Psychiatry 13:30-8. 2012
    ..To evaluate depressive symptoms regarding their association with the acute outcome in first-episode schizophrenia comparing risperidone and haloperidol...
  13. ncbi request reprint Akathisia and suicidal ideation in first-episode schizophrenia
    Florian Seemüller
    Department of Psychiatry and Psychotherapy, Ludwig Maximilians University, Munich, Germany
    J Clin Psychopharmacol 32:694-8. 2012
    ..The allocated treatment, anxiety, and nervousness had no influence. The present findings suggest a promoting effect of akathisia on suicidal ideation can not be ruled out in patients with FES...
  14. doi request reprint Influencing factors and predictors of early improvement in the acute treatment of schizophrenia and schizophrenia spectrum disorder
    Rebecca Schennach-Wolff
    Department of Psychiatry, Ludwig Maximilians University, Nussbaumstr 7, 80336 Munich, Germany
    J Psychiatr Res 45:1639-47. 2011
    ..To examine the influencing factors and predictors of early improvement in schizophrenia patients...
  15. doi request reprint Evaluating depressive symptoms in schizophrenia: a psychometric comparison of the Calgary Depression Scale for Schizophrenia and the Hamilton Depression Rating Scale
    Rebecca Schennach
    Department of Psychiatry and Psychotherapy, Ludwig Maximilians University, Munich, Germany
    Psychopathology 45:276-85. 2012
    ....
  16. doi request reprint Predictors of response and remission in the acute treatment of first-episode schizophrenia patients--is it all about early response?
    Rebecca Schennach-Wolff
    Department of Psychiatry and Psychotherapy, Ludwig Maximilians University, Munich, Germany
    Eur Neuropsychopharmacol 21:370-8. 2011
    ..To evaluate the predictive validity of early response compared to other well-known predictor variables in acutely ill first-episode patients...
  17. doi request reprint Short-term treatment with risperidone or haloperidol in first-episode schizophrenia: 8-week results of a randomized controlled trial within the German Research Network on Schizophrenia
    Hans Jurgen Moller
    Department of Psychiatry and Psychotherapy, Ludwig Maximilians University, Munich, Germany
    Int J Neuropsychopharmacol 11:985-97. 2008
    ..Risperidone has better extrapyramidal tolerability and treatment retention rate than the equivalent dose of haloperidol in these patients...
  18. doi request reprint Defining and predicting functional outcome in schizophrenia and schizophrenia spectrum disorders
    Rebecca Schennach-Wolff
    Department of Psychiatry and Psychotherapy, Ludwig Maximilians University, Munich, Germany
    Schizophr Res 113:210-7. 2009
    ..To assess criteria and to identify predictive factors for functional outcome. The criteria should cover all domains proposed by the Remission in Schizophrenia Working Group...
  19. ncbi request reprint Does clinical judgment of baseline severity and changes in psychopathology depend on the patient population? Results of a CGI and PANSS linking analysis in a naturalistic study
    Rebecca Schennach-Wolff
    Department of Psychiatry and Psychotherapy, Ludwig Maximilians University Munich, Munich, Germany
    J Clin Psychopharmacol 30:726-31. 2010
    ..Furthermore, these linking results were compared with those derived from randomized controlled trials to examine if the baseline severity might influence the linking results...
  20. ncbi request reprint Changes in the treatment of acute psychosis in a German public hospital from 1998 to 2004
    Tiemo Wessels
    Rhine Clinics Essen, Department of Psychiatry and Psychotherapy, University of Duisburg Essen, Virchowstr 174, Essen 45147, Germany
    Psychiatr Q 78:91-9. 2007
    ..The aim of our study was to investigate antipsychotic treatment strategies in acute schizophrenic episodes in a German university hospital...
  21. doi request reprint Attitude towards adherence in patients with schizophrenia at discharge
    Rebecca Schennach-Wolff
    Department of Psychiatry and Psychotherapy, Ludwig Maximilians University, Nussbaumstr 7, 80336 Munich, Germany
    J Psychiatr Res 43:1294-301. 2009
    ....
  22. doi request reprint An early improvement threshold to predict response and remission in first-episode schizophrenia
    Rebecca Schennach-Wolff
    Department of Psychiatry and Psychotherapy, Ludwig Maximilians University, Nussbaumstrasse 7, Muenchen 80336, Germany
    Br J Psychiatry 196:460-6. 2010
    ..Early improvement with treatment is thought to be important in patients with first-episode schizophrenia, yet a valid definition is still outstanding...
  23. doi request reprint The World Federation of Societies of Biological Psychiatry (WFSBP) guidelines for the biological treatment of substance use and related disorders. Part 2: Opioid dependence
    Michael Soyka
    Department of Psychiatry, Ludwig Maximilian University, Munich, Germany
    World J Biol Psychiatry 12:160-87. 2011
    ..To develop evidence-based practice guidelines for the pharmacological treatment of opioid abuse and dependence...
  24. doi request reprint Neuropsychological impairments predict the clinical course in schizophrenia
    Wolfgang Wolwer
    Department of Psychiatry and Psychotherapy, Heinrich Heine University Düsseldorf Rhineland State Clinics Düsseldorf, Bergische Landstrasse 2, Dusseldorf, Germany
    Eur Arch Psychiatry Clin Neurosci 258:28-34. 2008
    ....
  25. ncbi request reprint Psychotropic drug prescription in a psychiatric university hospital in Germany
    Eugen Davids
    Department of Psychiatry and Psychotherapy, Rhine Clinics Essen, University of Duisburg Essen, Virchowstr 174, 45147 Essen, Germany
    Prog Neuropsychopharmacol Biol Psychiatry 30:1109-16. 2006
    ..Such surveys should be carried out more frequently and simultaneously in different centers. Critical comparisons could help to optimize treatment...
  26. pmc Psychopathological characteristics and treatment response of first episode compared with multiple episode schizophrenic disorders
    Markus Jager
    Department of Psychiatry, Ludwig Maximilians University, Nussbaumstr 7, D 80336 Munich, Germany
    Eur Arch Psychiatry Clin Neurosci 257:47-53. 2007
    ..The aim was to investigate the hypothesis that patients with first episode schizophrenic disorders have a more favorable treatment response than those with multiple episodes...
  27. doi request reprint Early improvement as a predictor of remission and response in schizophrenia: Results from a naturalistic study
    M Jager
    Department of Psychiatry, Ludwig Maximilians University, Munich, Germany
    Eur Psychiatry 24:501-6. 2009
    ..To examine the predictive validity of early improvement in a naturalistic sample of inpatients and to identify the criterion that best defines early improvement...
  28. doi request reprint Outcome of suicidal patients with schizophrenia: results from a naturalistic study
    R Schennach-Wolff
    Department of Psychiatry and Psychotherapy, Ludwig Maximilians University, Munich, Germany
    Acta Psychiatr Scand 121:359-70. 2010
    ..Purpose was to assess suicidality before and at the time of admission in patients with schizophrenia and compare outcome differences...
  29. ncbi request reprint The efficacy of the dopamine D2/D3 antagonist tiapride in maintaining abstinence: a randomized, double-blind, placebo-controlled trial in 299 alcohol-dependent patients
    Stefan Bender
    Department of Psychiatry and Psychotherapy, Rhine State Hospital, University Hospital Essen, Germany
    Int J Neuropsychopharmacol 10:653-60. 2007
    ..Regarding the high success rate in the placebo group the influence of psychosocial treatment in studies investigating drug effects on the course of alcohol dependence has to be considered...
  30. ncbi request reprint A pilot clinical trial of oxcarbazepine in adults with attention-deficit hyperactivity disorder
    Eugen Davids
    Department of Psychiatry and Psychotherapy, Rhine Clinics Essen, University of Duisburg Essen, Virchowstr 174, 45147 Essen, Germany
    Prog Neuropsychopharmacol Biol Psychiatry 30:1033-8. 2006
    ..The results of this investigation indicate that oxcarbazepine may be a potentially useful agent for the treatment of ADHD in adults. However, placebo-controlled randomized trials are needed to provide evidence...
  31. ncbi request reprint Antipsychotic treatment of psychosis associated with multiple sclerosis
    Eugen Davids
    Department of Psychiatry and Psychotherapy, University of Duisburg Essen, Virchowstr 174, 45147, Germany
    Prog Neuropsychopharmacol Biol Psychiatry 28:743-4. 2004
    ..Risperidone was not administered with respect to possible EPS. However, ziprasidone was tolerated well and appeared to be effective...
  32. ncbi request reprint Age-related changes of the dentate nuclei in normal adults as revealed by 3D fast low angle shot (FLASH) echo sequence magnetic resonance imaging
    Matthias Maschke
    Department of Neurology, University of Duisburg Essen, Hufelandstr 55, 45122 Essen, Germany
    J Neurol 251:740-6. 2004
    ..These age-dependent changes have to be taken into account in interpretation of disease related MR changes of cerebellar nuclei in patients with degenerative or acquired cerebellar ataxia...
  33. ncbi request reprint Sympathetic neural activation evoked by mu-receptor blockade in patients addicted to opioids is abolished by intravenous clonidine
    Peter Kienbaum
    Abteilung für Anästhesiologie und Intensivmedizin, Universitatsklinikum, Essen, Germany
    Anesthesiology 96:346-51. 2002
    ....
  34. ncbi request reprint [Descriptive analysis of drug-related deaths over a 5-year period]
    Eugen Davids
    Klinik für Psychiatrie und Psychotherapie der Universität Essen, Rheinische Kliniken Essen
    Psychiatr Prax 30:266-71. 2003
    ..The purpose of the study was to examine opiate-related deaths in the German town Essen (inhabitants about 600,000) from 1990-1994. Sociodemographic data, psychiatric comorbidity and purity of the used opioids were of focussed interest...
  35. ncbi request reprint Lack of efficacy of naltrexone in the prevention of alcohol relapse: results from a German multicenter study
    Markus Gastpar
    Department of Psychiatry of the University of Essen, Germany
    J Clin Psychopharmacol 22:592-8. 2002
    ..Nevertheless, the question arises whether self-reports of drinking are more reliable than gamma-GT as a measure of recent alcohol consumption...
  36. ncbi request reprint Neuropsychological assessment of adult patients with attention-deficit/hyperactivity disorder
    Bernhard W Müller
    Clinic for Psychiatry and Psychotherapy, University of Duisburg Essen, Virchowstrasse 174, 45147 Essen, Germany
    Eur Arch Psychiatry Clin Neurosci 257:112-9. 2007
    ..Adults with ADHD show indicators of lowered cognitive performance under medication. These are related more to memory and attention under high mental load than to response inhibition or simple attention or motor performance...
  37. ncbi request reprint The intensity dependence of auditory ERP components in unmedicated patients with major depression and healthy controls. An analysis of group differences
    Thomas Linka
    Clinic for Psychiatry and Psychotherapy, Rheinische Kliniken Essen, University of Duisburg Essen, 45147 Essen, Germany
    J Affect Disord 103:139-45. 2007
    ..Therefore, the purpose of the present study was to compare the IDAP in unmedicated depressed patients with that of healthy control subjects...
  38. ncbi request reprint Treatment of acute alcohol withdrawal with gabapentin: results from a controlled two-center trial
    Udo Bonnet
    Department of Psychiatry and Psychotherapy, University of Essen, Essen, Germany
    J Clin Psychopharmacol 23:514-9. 2003
    ..The combination of GP and CLO was safe...
  39. ncbi request reprint [Escitalopram: a chiral agent for treatment of depression]
    Michael Overlack
    Klinik für Psychiatrie und Psychotherapie der Universität Duisburg Essen, Rheinische Kliniken Essen
    Med Monatsschr Pharm 27:148-51. 2004
  40. ncbi request reprint [Attention-deficit/hyperactivity disorder and substance abuse]
    Eugen Davids
    Rheinische Kliniken Essen, Klinik für Psychiatrie und Psychotherapie der Universität Duisburg Essen
    Psychiatr Prax 30:182-6. 2003
    ..Possible pharmacological and non-pharmacological therapeutic strategies in patients with ADHD and substance abuse are discussed...
  41. ncbi request reprint Vermal atrophy of alcoholics correlate with serum thiamine levels but not with dentate iron concentrations as estimated by MRI
    Matthias Maschke
    Department of Neurology, University Duisburg Essen, Hufelandstr 55, 45122 Essen, Germany
    J Neurol 252:704-11. 2005
    ..344, p = 0.028). These results support the view that thiamine deficiency rather than direct neurotoxic effects of alcohol is the main causative factor for the development of alcoholic cerebellar degeneration...
  42. ncbi request reprint [Analysis of a special consultation for attention deficit/hyperactivity disorder in adults]
    E Davids
    Klinik für Psychiatrie und Psychotherapie der Universität Duisburg Essen, Rheinische Kliniken Essen
    Gesundheitswesen 66:416-22. 2004
    ..Guidelines need to be drawn up to establish handover from paediatric to adult ADHD care...
  43. doi request reprint Time course of antipsychotic treatment response in schizophrenia: results from a naturalistic study in 280 patients
    M Jager
    Department of Psychiatry, Ludwig Maximilians University, Nussbaumstr 7, D 80336 Munich, Germany
    Schizophr Res 118:183-8. 2010
    ..To describe the course of positive and negative symptoms during inpatient treatment and examine remission and response rates under routine clinical care conditions...
  44. ncbi request reprint [Delusional depression as differential dementia of the Alzheimer type diagnosis]
    M Jüptner
    Klinik fur Psychiatrie und Psychotherapie, Universitatsklinikum Essen, Rheinische Kliniken, Virchowstrasse 174, 45147 Essen
    Nervenarzt 73:468-70. 2002
    ..Standardized and differential diagnoses of dementias are necessary for an antidementive therapy as well as for the detection of potentially curable diseases...
  45. ncbi request reprint Use of illegally acquired medical opioids by opiate-dependent patients in detoxification treatment
    N Scherbaum
    Department of Addictive Behavior and Addiction Medicine, Rheinische Kliniken Essen, University Hospital Essen, Essen, Germany
    Eur Addict Res 11:193-6. 2005
    ..Maintenance patients were usually the source of the opiates. The results prove the necessity of stringent conditions for take-home dosages, and illustrate deficits in the health care system...
  46. ncbi request reprint [Subjective experience of a computer-assisted cognitive training by patients with schizophrenia]
    S Bender
    Klinik für Psychiatrie und Psychotherapie der Universität Duisburg Essen Rheinische Kliniken Essen, Essen
    Nervenarzt 75:44-50. 2004
    ..Computer anxiety scores at onset of treatment did not exceed normal values. After completion of the training, these scores were significantly reduced and subjective well-being significantly increased...
  47. ncbi request reprint [Atomoxetine for the treatment of attention-deficit/hyperactivity disorder]
    E Davids
    Klinik für Psychiatrie und Psychotherapie der Universität Duisburg Essen, Rheinische Kliniken Essen, Essen
    Fortschr Neurol Psychiatr 72:586-91. 2004
    ..Atomoxetine is the first nonstimulant approved by the FDA for the treatment of ADHD and the first medication approved for the treatment of adult ADHD...
  48. ncbi request reprint Trimipramine--an atypical neuroleptic?
    G Eikmeier
    Department of General Psychiatry, University of Essen, Germany
    Int Clin Psychopharmacol 6:147-53. 1991
    ..Since the improvement of florid psychotic symptoms seems to be markedly higher under trimipramine than the one reported under placebo, our results indicate that trimipramine may have an antipsychotic potency...
  49. ncbi request reprint Transient restless legs-like syndrome as a complication of opiate withrawal
    N Scherbaum
    Department of Psychiatry and Psychotherapy, University Hospital, Essen, Germany
    Pharmacopsychiatry 36:70-2. 2003
    ..Transient RLS during opiate detoxification merits further interst in order to improve the treatment of sleep disturbances during detoxification and as a model of interaction of the dopaminergic and endorphine system in motor activity...
  50. ncbi request reprint Antipsychotic efficacy of the antidepressant trimipramine: a randomized, double-blind comparison with the phenothiazine perazine
    S Bender
    University of Essen, Clinic for Psychiatry and Psychotherapy, Germany
    Pharmacopsychiatry 36:61-9. 2003
    ..The aim of the study was to investigate the antipsychotic potential of trimipramine in a controlled clinical trial comparing its antipsychotic efficacy with that of a neuroleptic...
  51. ncbi request reprint The intensity dependence of auditory evoked ERP components predicts responsiveness to reboxetine treatment in major depression
    T Linka
    Clinic for Psychiatry and Psychotherapy, Rheinische Kliniken Essen, University of Duisburg Essen, Essen, Germany
    Pharmacopsychiatry 38:139-43. 2005
    ..In patients with major depression, associations of high IDAP with favorable SSRI treatment outcome have been reported. This is the first study to assess the predictive value of the IDAP in SNRI treatment...
  52. ncbi request reprint [Life events and contact behaviour in drug-related death]
    E Davids
    Klinik für Psychiatrie und Psychotherapie der Universität Essen, Rheinische Kliniken Essen
    Fortschr Neurol Psychiatr 71:135-40. 2003
    ..Turning away from the help system is not the reason for drug-related death, but an important attendant circumstance...
  53. ncbi request reprint Chronic mu-opioid receptor stimulation in humans decreases muscle sympathetic nerve activity
    P Kienbaum
    Abteilung für Anästhesiologie und Intensivmedizin, Biochemisches Forschungslabor, and Klinik für Psychiatrie und Psychotherapie, Universitatsklinikum Essen, Germany
    Circulation 103:850-5. 2001
    ..Furthermore, we assessed whether this effect is reversed by mu-opioid receptor blockade during antagonist-supported detoxification under general anesthesia...
  54. ncbi request reprint Cognitive-motor performance of methadone-maintained patients
    M Specka
    Department of Psychiatry, University of Essen, Germany
    Eur Addict Res 6:8-19. 2000
    ..To conclude, assessment of fitness for certain tasks or occupations should be done individually for each patient and should take into account comorbidity, including the extent of alcohol and other drug use...
  55. ncbi request reprint Profound increase in epinephrine concentration in plasma and cardiovascular stimulation after mu-opioid receptor blockade in opioid-addicted patients during barbiturate-induced anesthesia for acute detoxification
    P Kienbaum
    Abteilung für Anästhesiologie und Intensivmedizin, Universität GH Essen, Germany
    Anesthesiology 88:1154-61. 1998
    ..The authors tested the hypothesis that mu-opioid receptor blockade by naloxone induces cardiovascular stimulation mediated by the sympathoadrenal system...
  56. ncbi request reprint Group psychotherapy for opiate addicts in methadone maintenance treatment--a controlled trial
    N Scherbaum
    Department of Addictive Behavior and Addiction Medicine, Rheinische Kliniken Essen, University Hospital, Essen, Germany
    Eur Addict Res 11:163-71. 2005
    ..02). These findings underscore the usefulness of group psychotherapy in MMT. The delayed effect is comparable to other studies evaluating cognitive-behavioural psychotherapy...
  57. ncbi request reprint Safety and efficacy of combined clozapine-lithium pharmacotherapy
    Stefan Bender
    Department of Psychiatry and Psychotherapy, The University of Duisburg Essen, Essen, Germany
    Int J Neuropsychopharmacol 7:59-63. 2004
    ....
  58. ncbi request reprint History of attention-deficit hyperactivity disorder symptoms and opioid dependence: a controlled study
    Eugen Davids
    Department of Psychiatry and Psychotherapy, University of Duisburg Essen, Rhine Clinics Essen, Virchowstr 174, 45147 Essen, Germany
    Prog Neuropsychopharmacol Biol Psychiatry 29:291-6. 2005
    ..Patients with ADHD history seemed to experience a drug abuse career with more complications which need to be recognized with focused attention in order to start earlier treatment strategies...
  59. pmc Levo-alpha-acetylmethadol (LAAM) induced QTc-prolongation - results from a controlled clinical trial
    H Wieneke
    Department of Cardiology, University Hospital Essen, Essen, Germany
    Eur J Med Res 14:7-12. 2009
    ..The aim of the present study was to evaluate the relative impact of LAAM on QTc-interval, as a measure of pro-arrhythmic risk, in comparison to methadone, the current standard in substitution therapy...
  60. ncbi request reprint Effects of client-centered psychotherapy for personality disorders alone and in combination with psychopharmacological treatment. An empirical follow-up study
    L Teusch
    Department of Psychiatry and Psychotherapy, Evangelisches Krankenhaus Castrop-Rauxel, Germany
    Psychother Psychosom 70:328-36. 2001
    ..5-7). CONCLUSIONS: The results are discussed with regard to client-centered therapeutic concepts and to the further development of differential combination strategies...
  61. ncbi request reprint Attention deficit hyperactivity disorder and borderline personality disorder
    Eugen Davids
    Department of Psychiatry and Psychotherapy, University of Duisburg Essen Rhine Clinics Essen Virchowstrasse 174, 45147 Essen, Germany
    Prog Neuropsychopharmacol Biol Psychiatry 29:865-77. 2005
    ..From a neuropsychological point of view dissociation in BPD might be regarded as a special form of behavioral inhibition and sustained attention comparable to ADHD. Possible therapeutic strategies of comorbid ADHD and BPD are discussed...
  62. ncbi request reprint Somatic comorbidity of addicts: does hospitalization yield relevant findings?
    T Allhoff
    Department of Psychiatry and Psychotherapy, University Hospital Essen, Germany
    J Addict Dis 20:85-95. 2001
    ..The findings emphasize that hospitalization of addicted patients yields relevant somatic morbidity which has an impact on cost and requires medically supervised detoxification programs...
  63. ncbi request reprint Sexual dysfunction in psychiatric inpatients the role of antipsychotic medication
    J Westheide
    Department of Psychiatry and Psychotherapy, University of Bonn, Bonn, Germany
    Pharmacopsychiatry 40:140-5. 2007
    ....
  64. doi request reprint A randomized, open-label trial comparing methadone and Levo-Alpha-Acetylmethadol (LAAM) in maintenance treatment of opioid addiction
    J Wolstein
    Department of Psychiatry and Psychotherapy, Rhine State Hospital, University of Duisburg Essen, Essen, Germany
    Pharmacopsychiatry 42:1-8. 2009
    ..We report on the first European multi-center, parallel group, flexible dose, open-label, randomized clinical trial comparing LAAM and methadone in patients with opioid dependence...
  65. doi request reprint Standardized remission criteria in schizophrenia: descriptive validity and comparability with previously used outcome measures
    M Jager
    Department of Psychiatry, Ludwig Maximilians University, Munich, Germany
    Pharmacopsychiatry 41:190-5. 2008
    ..Standardized consensus criteria for remission in schizophrenia were recently proposed. As yet, the validity of these criteria and their comparability with previously used outcome measures are unclear...
  66. ncbi request reprint Buprenorphine in the treatment of opioid dependence
    Eugen Davids
    Rhine Clinics Essen, Department of Psychiatry and Psychotherapy, University of Duisburg Essen, Virchowstr 174, 45147 Essen, Germany
    Eur Neuropsychopharmacol 14:209-16. 2004
    ..Buprenorphine is an additional treatment option for heroin dependent patients, especially for those who do not wish to start or continue with methadone or for those who do not seem to benefit from adequate dosages of methadone...
  67. ncbi request reprint Concomitant endocrine and immune alterations during alcohol intoxication and acute withdrawal in alcohol-dependent subjects
    Sven Kutscher
    Clinic for Psychiatry and Psychotherapy, University of Essen, Essen, Germany
    Neuropsychobiology 45:144-9. 2002
    ..However, resolution of acute alcohol withdrawal is associated with a return of plasma cortisol to control levels, and a concomitant increase in peripheral blood monocyte numbers...
  68. ncbi request reprint [Sex-specific characteristics of mental disorders. Women are different]
    Markus Gastpar
    Fliedner Klinik Berlin, Ambulanz und Tagesklinik für psychologische Medizin, Berlin
    MMW Fortschr Med 149:24-5. 2007
  69. ncbi request reprint Buprenorphine and methadone in the treatment of opioid dependence: methods and design of the COBRA study
    Hans Ulrich Wittchen
    Institut für Klinische Psychologie und Psychotherapie, TU Dresden, Germany
    Int J Methods Psychiatr Res 14:14-28. 2005
    ..The COBRA study provides a unique comprehensive database, informing about the natural allocation and intervention processes in routine care and about the course and outcome of patients treated with buprenorphine or methadone...
  70. ncbi request reprint Chronic mu-opioid receptor stimulation alters cardiovascular regulation in humans: differential effects on muscle sympathetic and heart rate responses to arterial hypotension
    Peter Kienbaum
    Abteilung für Anästhsiologie und Intensivmedizin, Universitatsklinikum Essen, Germany
    J Cardiovasc Pharmacol 40:363-9. 2002
    ....
  71. ncbi request reprint Partial response and nonresponse to antidepressant therapy: current approaches and treatment options
    Robert M A Hirschfeld
    Department of Psychiatry and Behavioral Sciences, University of Texas Medical Branch, Galveston 77555 0188, USA
    J Clin Psychiatry 63:826-37. 2002
    ..Switching to an agent of a different class is probably optimal for those patients who fail to respond to first-line therapy...
  72. doi request reprint World Federation of Societies of Biological Psychiatry (WFSBP) Guidelines for Biological Treatment of Substance Use and Related Disorders, Part 1: Alcoholism
    Michael Soyka
    Psychiatric Hospital Meiringen, Meiringen, Switzerland
    World J Biol Psychiatry 9:6-23. 2008
    ..This first part of the guidelines covers the treatment of alcohol dependence; Part 2 will be devoted to the treatment of drug dependence...
  73. doi request reprint Feasibility and outcome of substitution treatment of heroin-dependent patients in specialized substitution centers and primary care facilities in Germany: a naturalistic study in 2694 patients
    Hans Ulrich Wittchen
    Institute of Clinical Psychology and Psychotherapy, Technische Universitaet Dresden, Chemnitzerstrasse 46, 01187 Dresden, Germany
    Drug Alcohol Depend 95:245-57. 2008
    ..Despite many short-term studies, little is known about the long-term (12-month) effects of these treatments in different settings, i.e. primary care-based (PMC) and specialized substitution centers (SSCs)...
  74. ncbi request reprint [The visit at home by a social worker of a psychiatric outpatient clinic]
    Markus Banger
    Rheinische Kliniken Bonn
    Psychiatr Prax 31:198-202. 2004
    ..The high rank of social work in context with psychiatric treatment of in-patients is generally accepted. The value of social work and here especially the visit at home by the social worker has hardly been examined up to now...
  75. ncbi request reprint Syphilis infection among drug addicts in western Germany
    Norbert Scherbaum
    Addiction 97:601-2. 2002
  76. ncbi request reprint Urine labeling with orally applied marker substances in drug substitution therapy
    Bernd Huppertz
    Kliniken der Stadt Köln, Zentrallabor, Cologne, Germany
    Clin Chem Lab Med 42:621-6. 2004
    ..Normal values for marker substances in urine were determined. The results suggest that this labeling procedure is a new diagnostic tool to prevent manipulation of urine samples by drug addicts receiving substitution therapy...