C D Garlichs

Summary

Affiliation: University of Erlangen-Nuremberg
Country: Germany

Publications

  1. ncbi request reprint Upregulation of CD40-CD40 ligand (CD154) in patients with acute cerebral ischemia
    C D Garlichs
    Medical Clinic II, Friedrich Alexander University Erlangen Nuremberg, David Morgenstern Weg 14, 91056 Erlangen, Germany
    Stroke 34:1412-8. 2003
  2. ncbi request reprint Delay of neutrophil apoptosis in acute coronary syndromes
    C D Garlichs
    Medicak Clinic II, Friedrich Alexander University of Erlangen Nurnberg, Erlangen, Germany
    J Leukoc Biol 75:828-35. 2004
  3. ncbi request reprint Beta-blockers reduce the release and synthesis of endothelin-1 in human endothelial cells
    C D Garlichs
    Medical Clinic II, Friedrich Alexander University Erlangen Nurnberg, Germany
    Eur J Clin Invest 29:12-6. 1999
  4. ncbi request reprint Priming of superoxide anion in polymorphonuclear neutrophils by brain natriuretic peptide
    C D Garlichs
    Medical Clinic II, Friedrich Alexander University Erlangen Nurnberg, Erlangen, Germany
    Life Sci 65:1027-33. 1999
  5. ncbi request reprint Upregulation of CD40 and CD40 ligand (CD154) in patients with moderate hypercholesterolemia
    C D Garlichs
    Medical Clinic II and Medical Clinic IV, Friedrich Alexander University, Erlangen Nurnberg, Germany
    Circulation 104:2395-400. 2001
  6. pmc Patients with acute coronary syndromes express enhanced CD40 ligand/CD154 on platelets
    C D Garlichs
    Medical Clinic II, Friedrich Alexander University Erlangen Nurnberg, Ostliche Stadmauerstrasser 29, 91054 Erlangen, Germany
    Heart 86:649-55. 2001
  7. ncbi request reprint Induction of cyclooxygenase-2 and enhanced release of prostaglandin E(2) and I(2) in human endothelial cells by engagement of CD40
    Christoph D Garlichs
    Medical Clinic II, Friedrich Alexander University Erlangen Nurnberg, Erlangen, Germany
    Atherosclerosis 163:9-16. 2002
  8. pmc Involvement of tyrosine kinases, Ca2+ and PKC in activation of mitogen-activated protein (MAP) kinase in human polymorphonuclear neutrophils
    H Zhang
    Department of Cardiology, Medical Clinic II, Friedrich Alexander University Erlangen Nurnberg, D 91054 Erlangen
    J Physiol 513:359-67. 1998
  9. doi request reprint CD40/CD154 system and pro-inflammatory cytokines in young healthy male smokers without additional risk factors for atherosclerosis
    C D Garlichs
    University of Erlangen Nuremberg, Medical Clinic 2, Erlangen, Germany
    Inflamm Res 58:306-11. 2009
  10. ncbi request reprint Angiotensin II-induced superoxide anion generation in human vascular endothelial cells: role of membrane-bound NADH-/NADPH-oxidases
    H Zhang
    Department of Cardiology, Friedrich Alexander University Erlangen Nurnberg, Germany
    Cardiovasc Res 44:215-22. 1999

Detail Information

Publications17

  1. ncbi request reprint Upregulation of CD40-CD40 ligand (CD154) in patients with acute cerebral ischemia
    C D Garlichs
    Medical Clinic II, Friedrich Alexander University Erlangen Nuremberg, David Morgenstern Weg 14, 91056 Erlangen, Germany
    Stroke 34:1412-8. 2003
    ..Both can be mediated by the CD40 system. This study investigated whether the CD40 system and related mediators are upregulated in patients with transient ischemic attack (TIA) or stroke...
  2. ncbi request reprint Delay of neutrophil apoptosis in acute coronary syndromes
    C D Garlichs
    Medicak Clinic II, Friedrich Alexander University of Erlangen Nurnberg, Erlangen, Germany
    J Leukoc Biol 75:828-35. 2004
    ..Therapeutical modulation of these determinants of PMN lifespan may provide a new concept for the control of inflammation in ACS...
  3. ncbi request reprint Beta-blockers reduce the release and synthesis of endothelin-1 in human endothelial cells
    C D Garlichs
    Medical Clinic II, Friedrich Alexander University Erlangen Nurnberg, Germany
    Eur J Clin Invest 29:12-6. 1999
    ..The aim of this study was to determine whether beta-adrenergic antagonists have an influence on endothelin-1 (ET-1) synthesis and release in human endothelial cells...
  4. ncbi request reprint Priming of superoxide anion in polymorphonuclear neutrophils by brain natriuretic peptide
    C D Garlichs
    Medical Clinic II, Friedrich Alexander University Erlangen Nurnberg, Erlangen, Germany
    Life Sci 65:1027-33. 1999
    ..Thus our data show that the cardiac-derived hormone BNP influences an important function of PMN. This 'priming' effect of BNP on PMN may contribute to the tissue damage occuring during acute coronary syndromes...
  5. ncbi request reprint Upregulation of CD40 and CD40 ligand (CD154) in patients with moderate hypercholesterolemia
    C D Garlichs
    Medical Clinic II and Medical Clinic IV, Friedrich Alexander University, Erlangen Nurnberg, Germany
    Circulation 104:2395-400. 2001
    ..This study investigated whether the CD40 system is upregulated in patients with moderate hypercholesterolemia and whether it is influenced by therapy with a hydroxymethylglutaryl coenzyme A (HMG-CoA) reductase inhibitor...
  6. pmc Patients with acute coronary syndromes express enhanced CD40 ligand/CD154 on platelets
    C D Garlichs
    Medical Clinic II, Friedrich Alexander University Erlangen Nurnberg, Ostliche Stadmauerstrasser 29, 91054 Erlangen, Germany
    Heart 86:649-55. 2001
    ..To investigate whether CD40L/CD154 on platelets and soluble CD40L/CD154 may play a role in the inflammatory process of acute coronary syndromes...
  7. ncbi request reprint Induction of cyclooxygenase-2 and enhanced release of prostaglandin E(2) and I(2) in human endothelial cells by engagement of CD40
    Christoph D Garlichs
    Medical Clinic II, Friedrich Alexander University Erlangen Nurnberg, Erlangen, Germany
    Atherosclerosis 163:9-16. 2002
    ..The hypothesis was tested that CD40-CD154 interaction is involved in the induction of cyclooxygenase-2 and the release of prostanoids in human endothelial cells...
  8. pmc Involvement of tyrosine kinases, Ca2+ and PKC in activation of mitogen-activated protein (MAP) kinase in human polymorphonuclear neutrophils
    H Zhang
    Department of Cardiology, Medical Clinic II, Friedrich Alexander University Erlangen Nurnberg, D 91054 Erlangen
    J Physiol 513:359-67. 1998
    ..However, a PMA-sensitive Ca2+-independent pathway also exists. Mobilization of Ca2+ and activation of PKC synergistically induce maximal MAP kinase activation and tyrosine phosphorylation...
  9. doi request reprint CD40/CD154 system and pro-inflammatory cytokines in young healthy male smokers without additional risk factors for atherosclerosis
    C D Garlichs
    University of Erlangen Nuremberg, Medical Clinic 2, Erlangen, Germany
    Inflamm Res 58:306-11. 2009
    ..We investigated whether smoking affects the CD40/CD154 system and pro-inflammatory cytokines in young males without other risk factors for atherosclerosis...
  10. ncbi request reprint Angiotensin II-induced superoxide anion generation in human vascular endothelial cells: role of membrane-bound NADH-/NADPH-oxidases
    H Zhang
    Department of Cardiology, Friedrich Alexander University Erlangen Nurnberg, Germany
    Cardiovasc Res 44:215-22. 1999
    ..These events finally lead to rapid progression of AS and MI. In the present study, we investigate whether ANG II can induce O2- release from human vascular endothelial cells (HVECs) and the possible mechanisms involved...
  11. ncbi request reprint Role of Ca2+-ATPase inhibitors in activation of cytosolic phospholipase A2 in human polymorphonuclear neutrophils
    H Zhang
    Department of Cardiology, Medical Clinic II, Friedrich Alexander University Erlangen Nurnberg, Erlangen, Germany
    Eur J Pharmacol 364:229-37. 1999
    ..Our results suggest that tyrosine kinases and the MAP kinase cascade are involved in Ca2+-ATPase inhibitor-induced activation and phosphorylation of cPLA2. Protein kinase C is not required in this event...
  12. ncbi request reprint Platelets contribute to enhanced MCP-1 levels in patients with chronic heart failure
    C Stumpf
    Department of Cardiology, University of Erlangen Nuremberg, Erlangen, Germany
    Heart 94:65-9. 2008
    ..Recently, platelets were identified as inducing inflammation partly by releasing cytokines. This new aspect necessitates further studies about the contribution of platelets for the inflammatory setting of CHF...
  13. doi request reprint Elevated VEGF-plasma levels in young patients with mild essential hypertension
    C Stumpf
    Department of Cardiology, University of Erlangen Nuremberg, Erlangen, Germany
    Eur J Clin Invest 39:31-6. 2009
    ..To investigate the hypothesis that VEGF plays a role as an inflammatory mediator in EH we performed the present pilot study of young patients in a very early stage of EH...
  14. ncbi request reprint Increased prolactin in acute coronary syndromes as putative Co-activator of ADP-stimulated P-selectin expression
    D Raaz
    Medical Clinic 2, University Hospital Erlangen, Germany
    Horm Metab Res 38:767-72. 2006
    ..Therefore, the stress hormone prolactin could be a co-stimulator of platelet activation in these patients. In contrast, the putative platelet activator leptin does not seem to play a major role in acute coronary syndromes...
  15. ncbi request reprint Rubbing salt into wounded endothelium: Sodium potentiates proatherogenic effects of TNF-α under non-uniform shear stress
    J Wild
    Iwona Cicha, PhD, Cardiovascular Nanomedicine Unit, Section of Experimental Oncology and Nanomedicine, ENT Department, University of Erlangen Nuremberg, Glückstr 10, 91054 Erlangen, Germany, Tel 49 9131 8543953, Fax 49 9131 8534282, E mail
    Thromb Haemost 112:183-95. 2014
    ....
  16. ncbi request reprint Dose-dependent disintegration of human endothelial monolayers by contrast echocardiography
    U Nixdorff
    2nd Medical Clinic, Friedrich Alexander University, Erlangen Nuremberg, Germany
    Life Sci 77:1493-501. 2005
    ..Diagnostic contrast echocardiography may induce endothelial disintegrations dependent on US output as well as on CA concentrations. This aspect might be helpful in further in vivo series on local drug delivery...
  17. ncbi request reprint Lack of relevant association between prolactin and immune responses in patients with chronic heart failure
    H Wallaschofski
    Eur J Clin Invest 33:1018; author reply 1019. 2003