Edeltraut Garbe

Summary

Affiliation: University of Bremen
Country: Germany

Publications

  1. ncbi request reprint Non-chemotherapy drug-induced agranulocytosis
    Edeltraut Garbe
    University Professor of Clinical Epidemiology, Bremen Institute for Prevention Research and Social Medicine, Bremen, Germany
    Expert Opin Drug Saf 6:323-35. 2007
  2. doi request reprint Linkage of mother-baby pairs in the German Pharmacoepidemiological Research Database
    Edeltraut Garbe
    Bremen Institute for Prevention Research and Social Medicine, University of Bremen, Germany
    Pharmacoepidemiol Drug Saf 20:258-64. 2011
  3. ncbi request reprint Evaluating methods for intersectoral comparison of quality of care. A routine data analysis of elective percutaneous coronary interventions
    C Ohlmeier
    Prof Dr Edeltraut Garbe, Leibniz Institute for Prevention Research and Epidemiology BIPS, Head of Department of Clinical Epidemiology, Achterstraße 30, 28359 Bremen, Germany, E mail
    Methods Inf Med 53:269-77. 2014
  4. ncbi request reprint Systemic antibiotic prescribing to paediatric outpatients in 5 European countries: a population-based cohort study
    Jakob Holstiege
    Leibniz Institute for Prevention Research and Epidemiology, BIPS, Achterstr, 30, 28359 Bremen, Germany
    BMC Pediatr 14:174. 2014
  5. pmc Twin and sibling studies using health insurance data: the example of attention deficit/hyperactivity disorder (ADHD)
    Ingo Langner
    Department of Clinical Epidemiology, Leibniz Institute for Prevention Research and Epidemiology, BIPS GmbH, Bremen, Germany
    PLoS ONE 8:e62177. 2013
  6. doi request reprint Risk of subarachnoid hemorrhage and early case fatality associated with outpatient antithrombotic drug use
    Edeltraut Garbe
    Department of Clinical Epidemiology, Leibniz Institute for Prevention Research and Epidemiology BIPS, Bremen, Germany
    Stroke 44:2422-6. 2013
  7. pmc Drug treatment patterns of attention-deficit/hyperactivity disorder in children and adolescents in Germany: results from a large population-based cohort study
    Edeltraut Garbe
    BIPS Institute for Epidemiology and Prevention Research, Bremen, Germany
    J Child Adolesc Psychopharmacol 22:452-8. 2012
  8. doi request reprint High-dimensional versus conventional propensity scores in a comparative effectiveness study of coxibs and reduced upper gastrointestinal complications
    E Garbe
    Department of Clinical Epidemiology, BIPS Institute for Epidemiology and Prevention Research, Achterstr 30, 28359 Bremen, Germany
    Eur J Clin Pharmacol 69:549-57. 2013
  9. doi request reprint Drug-induced immune thrombocytopaenia: results from the Berlin Case-Control Surveillance Study
    Edeltraut Garbe
    Centre of Clinical Pharmacology and Toxicology, Charite Universitatsmedizin Berlin, Berlin, Germany
    Eur J Clin Pharmacol 68:821-32. 2012
  10. ncbi request reprint Drug induced immune haemolytic anaemia in the Berlin Case-Control Surveillance Study
    Edeltraut Garbe
    Bremen Institute for Prevention Research and Social Medicine, University of Bremen, Bremen, Germany
    Br J Haematol 154:644-53. 2011

Collaborators

Detail Information

Publications44

  1. ncbi request reprint Non-chemotherapy drug-induced agranulocytosis
    Edeltraut Garbe
    University Professor of Clinical Epidemiology, Bremen Institute for Prevention Research and Social Medicine, Bremen, Germany
    Expert Opin Drug Saf 6:323-35. 2007
    ..Case fatality has decreased to ~ 5% in recent years, probably owing to improved intensive care treatment and increased alertness of physicians to this severe adverse reaction...
  2. doi request reprint Linkage of mother-baby pairs in the German Pharmacoepidemiological Research Database
    Edeltraut Garbe
    Bremen Institute for Prevention Research and Social Medicine, University of Bremen, Germany
    Pharmacoepidemiol Drug Saf 20:258-64. 2011
    ..Our study aimed to develop an algorithm for linkage of mother-baby pairs (MBPs) in the German Pharmacoepidemiological Research Database (GePaRD) as a prerequisite for such studies...
  3. ncbi request reprint Evaluating methods for intersectoral comparison of quality of care. A routine data analysis of elective percutaneous coronary interventions
    C Ohlmeier
    Prof Dr Edeltraut Garbe, Leibniz Institute for Prevention Research and Epidemiology BIPS, Head of Department of Clinical Epidemiology, Achterstraße 30, 28359 Bremen, Germany, E mail
    Methods Inf Med 53:269-77. 2014
    ..To compare the quality of care regarding the use of elective percutaneous coronary interventions (PCIs) in the inpatient and outpatient setting and to evaluate different methods of confounder control in this context...
  4. ncbi request reprint Systemic antibiotic prescribing to paediatric outpatients in 5 European countries: a population-based cohort study
    Jakob Holstiege
    Leibniz Institute for Prevention Research and Epidemiology, BIPS, Achterstr, 30, 28359 Bremen, Germany
    BMC Pediatr 14:174. 2014
    ..Special attention was given to age-group-specific distributions of antibiotic subgroups, since comparison in this regard between countries is lacking so far...
  5. pmc Twin and sibling studies using health insurance data: the example of attention deficit/hyperactivity disorder (ADHD)
    Ingo Langner
    Department of Clinical Epidemiology, Leibniz Institute for Prevention Research and Epidemiology, BIPS GmbH, Bremen, Germany
    PLoS ONE 8:e62177. 2013
    ..To show the feasibility of such research on the basis of health insurance data, we analysed twin and sibling data on the attention deficit/hyperactivity disorder (ADHD) in the German Pharmacoepidemiological Research Database (GePaRD)...
  6. doi request reprint Risk of subarachnoid hemorrhage and early case fatality associated with outpatient antithrombotic drug use
    Edeltraut Garbe
    Department of Clinical Epidemiology, Leibniz Institute for Prevention Research and Epidemiology BIPS, Bremen, Germany
    Stroke 44:2422-6. 2013
    ..We investigated the risk of SAH associated with prior use of antithrombotic drugs and their influence on 30-day case fatality...
  7. pmc Drug treatment patterns of attention-deficit/hyperactivity disorder in children and adolescents in Germany: results from a large population-based cohort study
    Edeltraut Garbe
    BIPS Institute for Epidemiology and Prevention Research, Bremen, Germany
    J Child Adolesc Psychopharmacol 22:452-8. 2012
    ....
  8. doi request reprint High-dimensional versus conventional propensity scores in a comparative effectiveness study of coxibs and reduced upper gastrointestinal complications
    E Garbe
    Department of Clinical Epidemiology, BIPS Institute for Epidemiology and Prevention Research, Achterstr 30, 28359 Bremen, Germany
    Eur J Clin Pharmacol 69:549-57. 2013
    ....
  9. doi request reprint Drug-induced immune thrombocytopaenia: results from the Berlin Case-Control Surveillance Study
    Edeltraut Garbe
    Centre of Clinical Pharmacology and Toxicology, Charite Universitatsmedizin Berlin, Berlin, Germany
    Eur J Clin Pharmacol 68:821-32. 2012
    ..To characterize the spectrum of drugs associated with immune thrombocytopaenia (ITP) in the Berlin Case-Control Surveillance Study (FAKOS)...
  10. ncbi request reprint Drug induced immune haemolytic anaemia in the Berlin Case-Control Surveillance Study
    Edeltraut Garbe
    Bremen Institute for Prevention Research and Social Medicine, University of Bremen, Bremen, Germany
    Br J Haematol 154:644-53. 2011
    ..It corroborates an increased risk for several drugs that have been implicated as a cause of IHA in the standardized causality assessment of individual cases...
  11. ncbi request reprint Utilisation of transdermal fentanyl in Germany from 2004 to 2006
    Edeltraut Garbe
    Bremen Institute for Prevention Research and Social Medicine BIPS, Bremen, Germany
    Pharmacoepidemiol Drug Saf 21:191-8. 2012
    ..The aim of this study was to characterise utilisation of transdermal fentanyl in Germany...
  12. ncbi request reprint Age-specific prevalence, incidence of new diagnoses, and drug treatment of attention-deficit/hyperactivity disorder in Germany
    Christina Lindemann
    Bremen Institute for Prevention Research and Social Medicine, Bremen, Germany
    J Child Adolesc Psychopharmacol 22:307-14. 2012
    ..The purpose of this study was to estimate the prevalence and incidence of new diagnoses of attention-deficit/hyperactivity disorder (ADHD) and assess drug treatment of ADHD in the 3-17 year age group in Germany...
  13. pmc Comorbidities in ADHD children treated with methylphenidate: a database study
    Angela A Kraut
    Department of Clinical Epidemiology, Leibniz Institute for Prevention Research and Epidemiology BIPS, Bremen, Germany
    BMC Psychiatry 13:11. 2013
    ..We assessed MPH treatment prevalence and incidence and the frequency of comorbid conditions related to these contraindications in new MPH users compared to a control group without ADHD and ADHD medication...
  14. ncbi request reprint Cyclooxygenase-2 selective nonsteroidal anti-inflammatory drugs and the risk of ischemic stroke: a nested case-control study
    Frank Andersohn
    Department of Clinical Pharmacology, Charite Universitaetsmedizin Berlin, Berlin, Germany
    Stroke 37:1725-30. 2006
    ..Few data are available concerning the risk of ischemic stroke associated with COX-2 inhibitors...
  15. ncbi request reprint Drug interactions with phenprocoumon and the risk of serious haemorrhage: a nested case-control study in a large population-based German database
    Kathrin Jobski
    Bremen Institute for Prevention Research and Social Medicine BIPS, University of Bremen, Achterstrasse 30, 28359, Bremen, Germany
    Eur J Clin Pharmacol 67:941-51. 2011
    ..Phenprocoumon is the most frequently used vitamin K antagonist in Germany. The aim of this study was to estimate the risk of serious bleeding as a result of the use of drugs with potential interaction with phenprocoumon...
  16. pmc Incidence of anogenital warts in Germany: a population-based cohort study
    Angela A Kraut
    Department of Clinical Epidemiology, Bremen Institute for Prevention Research and Social Medicine BIPS, Achterstrasse 30, 28359 Bremen, Germany
    BMC Infect Dis 10:360. 2010
    ..Additionally, the medical practitioner (gynaecologist, dermatologist, urologist etc.) who made the initial diagnosis of AGW was assessed...
  17. doi request reprint Drug-induced agranulocytosis in the Berlin case-control surveillance study
    Matthias Huber
    Institute of Clinical Pharmacology and Toxicology, Charite Universitatsmedizin Berlin, Berlin, Germany
    Eur J Clin Pharmacol 70:339-45. 2014
    ..Drug-induced agranulocytosis (DIAG) is a rare but serious adverse drug reaction. The Berlin Case-Control Surveillance Study (FAKOS) aimed to identify pharmaceuticals with an increased risk for this condition...
  18. doi request reprint Risk of intracerebral hemorrhage associated with phenprocoumon exposure: a nested case-control study in a large population-based German database
    Sigrid Behr
    Bremen Institute for Prevention Research and Social Medicine BIPS, Bremen, Germany
    Pharmacoepidemiol Drug Saf 19:722-30. 2010
    ..Intracerebral hemorrhage (ICH) is the most serious complication of oral anticoagulation. This study investigated the risk of ICH for phenprocoumon which is the most widely used oral anticoagulant in Germany...
  19. ncbi request reprint Use of antiepileptic drugs in epilepsy and the risk of self-harm or suicidal behavior
    Frank Andersohn
    Institute for Social Medicine, Epidemiology and Health Economics, Charite University Medical Center, Berlin, Germany
    Neurology 75:335-40. 2010
    ..We conducted an observational study with data from the United Kingdom General Practice Research Database to investigate if an increase in risk for different groups of AEDs is also evident in clinical practice...
  20. ncbi request reprint Incidence, prevalence, and antithrombotic management of atrial fibrillation in elderly Germans
    Christoph Ohlmeier
    Department of Clinical Epidemiology, Leibniz Institute for Prevention Research and Epidemiology BIPS, Achterstraße 30, D 28359 Bremen, Germany
    Europace 15:1436-44. 2013
    ..The aims of this study were to estimate the incidence and prevalence of AF in the elderly in Germany and to describe antithrombotic management of AF cases...
  21. doi request reprint Antidepressant drug use and off-label prescribing in children and adolescents in Germany: results from a large population-based cohort study
    Michael Dörks
    BIPS Institute for Epidemiology and Prevention Research, Achterstr, 30, 28359, Bremen, Germany
    Eur Child Adolesc Psychiatry 22:511-8. 2013
    ..26, 95% CI 2.05-2.48) of receiving an off-label prescription compared to treatment by general practitioners. In summary, off-label use of ATDs in children and adolescents was substantial in Germany...
  22. doi request reprint Flupirtine-induced liver injury--seven cases from the Berlin Case-control Surveillance Study and review of the German spontaneous adverse drug reaction reporting database
    Antonios Douros
    Department of Clinical Pharmacology and Toxicology, Charite Universitatsmedizin Berlin, Berlin, Germany
    Eur J Clin Pharmacol 70:453-9. 2014
    ..This study was conducted to further elucidate the clinical pattern of flupirtine-induced liver injury (FILI)...
  23. ncbi request reprint Dopamine agonists and the risk of cardiac-valve regurgitation
    René Schade
    Department of Clinical Pharmacology, Charite Campus Mitte, Charite Universitatsmedizin Berlin, Berlin
    N Engl J Med 356:29-38. 2007
    ....
  24. doi request reprint Changes in incidence of anogenital warts diagnoses after the introduction of human papillomavirus vaccination in Germany-an ecologic study
    Rafael T Mikolajczyk
    BIPS Institute for Epidemiology and Prevention Research, Bremen, Germany
    Sex Transm Dis 40:28-31. 2013
    ..0001). The decrease started between the first and second quarter of 2007 (human papillomavirus vaccination was introduced in March 2007)...
  25. doi request reprint 3-year prevalence of alcohol-related disorders in German patients treated with high-potency opioids
    Kathrin Jobski
    BIPS Institute for Epidemiology and Prevention Research, Bremen, Germany
    Pharmacoepidemiol Drug Saf 21:1125-9. 2012
    ..The aim of this study was to estimate the prevalence of alcohol-related disorders (ARD) in German patients treated with HPO approved for pain therapy...
  26. doi request reprint Cardiac and noncardiac fibrotic reactions caused by ergot-and nonergot-derived dopamine agonists
    Frank Andersohn
    Bremen Institute for Prevention Research and Social Medicine, University of Bremen, Germany
    Mov Disord 24:129-33. 2009
    ..Fibrotic reactions due to ergot-derived dopamine agonists may not be limited to heart valves. For nonergot-derived dopamine agonists, no drug safety signals were evident...
  27. doi request reprint Long-term use of antidepressants for depressive disorders and the risk of diabetes mellitus
    Frank Andersohn
    Bremen Institute for Prevention Research and Social Medicine, Bremen, Germany
    Am J Psychiatry 166:591-8. 2009
    ..The aim of this study was to assess the risk of diabetes mellitus associated with antidepressant treatment and to examine whether the risk is influenced by treatment duration or daily dose...
  28. pmc Regional variation in caesarean deliveries in Germany and its causes
    Rafael T Mikolajczyk
    Department of Clinical Epidemiology, Leibniz Institute for Prevention Research and Epidemiology BIPS, Bremen, Germany
    BMC Pregnancy Childbirth 13:99. 2013
    ....
  29. doi request reprint Signals of progressive multifocal leukoencephalopathy for immunosuppressants: a disproportionality analysis of spontaneous reports within the US Adverse Event Reporting System (AERS)
    Niklas Schmedt
    BIPS Institute for Epidemiology and Prevention Research, Germany
    Pharmacoepidemiol Drug Saf 21:1216-20. 2012
    ..We aimed to study signals of PML for immunosuppressants using a disproportionality analysis of spontaneous adverse event reports...
  30. ncbi request reprint Priapism associated with antipsychotics: role of alpha1 adrenoceptor affinity
    Frank Andersohn
    Institute for Social Medicine, Epidemiology and Health Economics, Charite University Medical Center, Berlin, Germany
    J Clin Psychopharmacol 30:68-71. 2010
    ..The observed pattern of signals indicates a relationship between alpha1 affinities of antipsychotics and the occurrence of priapism...
  31. ncbi request reprint Risk of febrile convulsions after MMRV vaccination in comparison to MMR or MMR+V vaccination
    Tania Schink
    Leibniz Institute for Prevention Research and Epidemiology BIPS, Achterstraße 30, 28359 Bremen, Germany Electronic address
    Vaccine 32:645-50. 2014
    ....
  32. doi request reprint Ramipril-induced liver injury: case report and review of the literature
    Antonios Douros
    Department of Clinical Pharmacology and Toxicology, Charite Universitatsmedizin Berlin, Berlin, Germany
    Am J Hypertens 26:1070-5. 2013
    ..Here, we present the first case of ramipril-induced liver injury proven by positive rechallenge and a review of the literature including the data from the US Food and Drug Administration adverse event reporting system (FAERS)...
  33. ncbi request reprint Epidemiology of symptomatic drug-induced long QT syndrome and torsade de pointes in Germany
    Giselle Sarganas
    Clinical Pharmacology and Toxicology, Charite Universitatsmedizin Berlin, Chariteplatz 1, 10117 Berlin, Germany
    Europace 16:101-8. 2014
    ..Here, the basic characteristics of the affected patients are summarized and suspected drugs are discussed. Furthermore, an extrapolation of the Berlin incidence rates to the German Standard Population is presented...
  34. ncbi request reprint Contraindication labelling changes in the United States and Germany
    Edeltraut Garbe
    Department of Clinical Pharmacology, Charite Universitatsmedizin Berlin, Chariteplatz 1, 10117 Berlin, Germany
    Eur J Clin Pharmacol 63:87-93. 2007
    ..Contraindication labelling provides the strongest safety-based guidance for the health care practitioner. In this study, the labelling of new contraindications between the United States (US) and Germany was compared...
  35. ncbi request reprint Use of first- and second-generation cyclooxygenase-2-selective nonsteroidal antiinflammatory drugs and risk of acute myocardial infarction
    Frank Andersohn
    Department of Clinical Pharmacology, Charite Universitaetsmedizin Berlin, Berlin, Germany
    Circulation 113:1950-7. 2006
    ..Whether the newer second-generation COX-2 inhibitors (etoricoxib, valdecoxib) also increase the cardiovascular risk is unknown...
  36. pmc Severe sustained cholestatic hepatitis following temozolomide in a patient with glioblastoma multiforme: case study and review of data from the FDA adverse event reporting system
    Giselle Sarganas
    Clinical Pharmacology and Toxicology, Charite Universitatsmedizin Berlin, Berlin, Germany
    Neuro Oncol 14:541-6. 2012
    ..Thus, TZM appears to cause different types of hepatotoxicity. Particular attention should be paid to sustained cholestasis as a very serious type of TZM-associated liver toxicity...
  37. ncbi request reprint Proportion of drug-related serious rare blood dyscrasias: estimates from the Berlin Case-Control Surveillance Study
    Frank Andersohn
    Institute of Clinical Pharmacology, Charite University Medicine Berlin, Campus Charite Mitte, Berlin, Germany
    Am J Hematol 77:316-8. 2004
    ..Our analysis suggests that a substantial fraction of blood dyscrasias may be attributable to drug therapy...
  38. ncbi request reprint Systematic review: agranulocytosis induced by nonchemotherapy drugs
    Frank Andersohn
    Department of Clinical Pharmacology and Toxicology, Charite Universitaetsmedizin Berlin, Berlin, Germany
    Ann Intern Med 146:657-65. 2007
    ..Nonchemotherapy drug-induced agranulocytosis is a rare adverse reaction that is characterized by a decrease in peripheral neutrophil count to less than 0.5 x 10(9) cells/L due to immunologic or cytotoxic mechanisms...
  39. doi request reprint Treatment of paediatric epilepsy in Germany: antiepileptic drug utilisation in children and adolescents with a focus on new antiepileptic drugs
    Michael Dörks
    University of Bremen, Bremen Institute for Prevention Research and Social Medicine BIPS, Achterstr 30, 28359 Bremen, Germany
    Epilepsy Res 103:45-53. 2013
    ..Treatment of paediatric epilepsy has advanced with the development of new antiepileptic drugs (AEDs). There are few data for Germany to which extent new AEDs are used in the treatment of childhood epilepsy...
  40. doi request reprint Systemic antibiotic use among children and adolescents in Germany: a population-based study
    Jakob Holstiege
    Institute for Epidemiology and Prevention Research BIPS, Achterstr 30, 28359 Bremen, Germany
    Eur J Pediatr 172:787-95. 2013
    ..11 %) and narrow-spectrum penicillins (16.45 %) were most frequent. The most common indication for antibiotic prescribing was tonsillitis followed by bronchitis, otitis media, acute upper respiratory infections and scarlet fever...
  41. pmc Use of rivaroxaban in Germany: a database drug utilization study of a drug started in hospital
    Kathrin Jobski
    Leibniz Institute for Prevention Research and Epidemiology BIPS GmbH, Achter Str 30, 28359, Bremen, Germany
    Eur J Clin Pharmacol 70:975-81. 2014
    ..Additionally, we explored the feasibility of reconstructing inpatient drug use of rivaroxaban in a database where with a few exceptions inpatient prescribing information is not available...
  42. pmc Regional and temporal variations in coding of hospital diagnoses referring to upper gastrointestinal and oesophageal bleeding in Germany
    Ingo Langner
    Bremen Institute for Prevention Research and Social Medicine, Bremen University, Germany
    BMC Health Serv Res 11:193. 2011
    ..The aim of this study was to investigate regional and temporal variations in coding of hospitalisation diagnoses in Germany...
  43. doi request reprint Antipsychotic drug use and the risk of venous thromboembolism in elderly patients with dementia
    Niklas Schmedt
    From the Leibniz Institute for Prevention Research and Epidemiology BIPS GmbH, and Faculty of Human and Health Sciences, University of Bremen, Bremen, Germany
    J Clin Psychopharmacol 33:753-8. 2013
    ..40). Increased attention to clinical signs of VTE should be paid during the first 3 months of treatment with antipsychotics and in patients receiving both conventional and atypical agents, especially if other risk factors for VTE exist. ..
  44. pmc Case-control study on analgesics and nephropathy (SAN): protocol
    Lothar A J Heinemann
    Centre for Epidemiology and Health Research Berlin, Invalidenstr 115, 10115 Berlin, Germany
    BMC Nephrol 6:9. 2005
    ..The association between intake of non-phenacetin-containing analgesics and the occurrence of chronic renal failure is still controversially discussed. A new epidemiologic study was planned and conducted in Germany and Austria...