Affiliation: University of Freiburg
- Polysomnographic comparison between patients with primary alcohol dependency during subacute withdrawal and patients with a major depressionHorst Gann
Department of Psychiatry and Psychotherapy, University of Freiburg, Hauptstrasse 5, 79104 Freiburg, Germany
Eur Arch Psychiatry Clin Neurosci 254:263-71. 2004..Such adaptive counterregulation might also explain the alterations in slow wave sleep found in alcoholics that are even more pronounced in these patients than in patients with major depression...
- The effects of clomethiazole on polysomnographically recorded sleep in healthy subjectsHorst Gann
Department of Psychiatry and Psychotherapy, University Hospital of Freiburg, 79104 Freiburg, Germany
Eur Arch Psychiatry Clin Neurosci 255:284-90. 2005....
- Polysomnography during withdrawal with clomethiazole or placebo in alcohol dependent patients--a double-blind and randomized studyH Gann
Dept of Psychiatry and Psychotherapy, University of Freiburg, Germany
Pharmacopsychiatry 37:228-35. 2004..The present study was designed to assess if the routine application of clomethiazole to ameliorate withdrawal symptoms in chronic alcohol dependent patients perpetuates sleep disturbances...
- Periodic limb movements during sleep in alcohol dependent patientsHorst Gann
Department of Psychiatry and Psychotherapy, University of Freiburg, Hauptstr 5, 79104 Freiburg, Germany
Eur Arch Psychiatry Clin Neurosci 252:124-9. 2002....
- [The importance of sleep for healthy alcohol consumers and alcohol dependent patients]H Gann
Abteilung für Psychiatrie und Psychotherapie mit Poliklinik, Universitätsklinik für Psychiatrie und Psychosomatik, Freiburg i Br
Nervenarzt 75:431-41. 2004..Neurobiological findings in sleep and alcohol dependency are discussed. The cholinergic-aminergic reciprocal interaction model of REM and non-REM sleep regulation is significant in this context. Therapeutic implications are discussed...
- Sleep and the cholinergic rapid eye movement sleep induction test in patients with primary alcohol dependenceH Gann
Department of Psychiatry and Psychotherapy, University of Freiburg, Hauptstr. 5, Freiburg D-79104, Germany
Biol Psychiatry 50:383-90. 2001..Thus, a subgroup of alcoholic patients appears to exhibit distinct neurobiological abnormalities assessable by polysomnography that are related to an increased vulnerability for alcoholism and early relapse...
- Auditory and visual event-related potentials in alcoholics: abnormalities of components and brain electrical fieldH M Olbrich
Psychiatric University Clinic, Freiburg, Germany
Eur Arch Psychiatry Clin Neurosci 250:215-20. 2000..Abnormalities of N1 amplitude and P3 topography similar to the current findings in alcoholics have previously been described for schizophrenics...
- Transient total sleep loss in cerebral Whipple's disease: a longitudinal studyUlrich Voderholzer
Department of Psychiatry and Psychotherapy, University of Freiburg, Freiburg, Germany
J Sleep Res 11:321-9. 2002..The extent of sleep disruption in this case of organic insomnia was similar to cases of familial fatal insomnia, but was at least partially reversible with treatment...
- Assessing cerebral dysfunction with probe-evoked potentials in a CNV task -- a study in alcoholicsHans M Olbrich
Department of Psychiatry and Psychotherapy, Albert Ludwigs University Freiburg, Hauptstrasse 5, 79104 Freiburg, Germany
Clin Neurophysiol 113:815-25. 2002..Focussing on slow waves (SWs) and on patients with mild cerebral dysfunction, we recorded ERPs in alcoholics using a dual task design...
- Magnesium treatment of primary alcohol-dependent patients during subacute withdrawal: an open pilot study with polysomnographyMagdolna Hornyak
Department of Psychiatry and Psychotherapy, University Hospital of Freiburg, Hauptstrasse 5, D 79104 Freiburg, Germany
Alcohol Clin Exp Res 28:1702-9. 2004..We conducted an open pilot study to evaluate the effects of magnesium treatment on the sleep of primary alcohol-dependent patients during subacute withdrawal...
- Neurobiological findings before and during successful lithium therapy of a patient with 48-hour rapid-cycling bipolar disorderUlrich Voderholzer
Department of Psychiatry and Psychotherapy, Albert Ludwig University, Freiburg, Germany
Neuropsychobiology 45:13-9. 2002..With plasma levels between 0.8 and 1.0 mmol, almost complete remission occurred. An overview on previous reports on the therapeutic effect of mood stabilizers in this rare form of bipolar disorder is presented...
- Effects of alcohol on polysomnographically recorded sleep in healthy subjectsBernd Feige
Department of Psychiatry and Psychotherapy, University Hospital of Freiburg, Freiburg, Germany
Alcohol Clin Exp Res 30:1527-37. 2006..The study evaluated a short-term acute drinking period for 3 and 2 days of withdrawal from alcohol not only for polysomnographic variables but also for subjective estimates of sleep quality...
- Sleep electroencephalographic spectral power after withdrawal from alcohol in alcohol-dependent patientsBernd Feige
Department of Psychiatry and Psychotherapy, University of Freiburg, Hauptstrasse 5, Freiburg 79104, Germany
Alcohol Clin Exp Res 31:19-27. 2007..Our hypothesis was that the subgroup of patients who relapsed within the 3 months to follow-up would exhibit-increased dysfunctional arousal manifested by higher-frequency (beta) EEG power during sleep...
- Cannabinoid receptor 1 blocker rimonabant (SR 141716) for treatment of alcohol dependence: results from a placebo-controlled, double-blind trialMichael Soyka
Department of Psychiatry, Ludwig Maximilian University of Munich, Munich, Germany
J Clin Psychopharmacol 28:317-24. 2008..Taking the substantial numbers of animal studies suggesting a possible role of CB1 antagonists for the treatment of alcohol dependence into account, it seems worthwhile to further test cannabinoid blockers in the treatment of alcoholism...