R E Friedrich

Summary

Affiliation: University of Hamburg
Country: Germany

Publications

  1. ncbi request reprint Malignant peripheral nerve sheath tumors (MPNST) in NF1-affected children
    R E Friedrich
    Maxillofacial Surgery, University Hospital Hamburg Eppendorf, University of Hamburg, Hamburg, Germany
    Anticancer Res 27:1957-60. 2007
  2. ncbi request reprint MRI growth patterns of plexiform neurofibromas in patients with neurofibromatosis type 1
    V F Mautner
    Section for Phakomatoses, Department of Maxillofacial Surgery, University Hospital Eppendorf, Hamburg, Germany
    Neuroradiology 48:160-5. 2006
  3. ncbi request reprint Clinical relevance of positron emission tomography and magnetic resonance imaging in the progression of internal plexiform neurofibroma in NF1
    V F Mautner
    Section of Phacomatoses, Maxillofacial Surgery, Eppendorf University Hospital, University of Hamburg, Germany
    Anticancer Res 27:1819-22. 2007
  4. ncbi request reprint Mutations and allelic loss of the NF2 gene in neurofibromatosis 2-associated skin tumors
    L Kluwe
    Laboratory for Brain Tumor Biology, Department of Neurosurgery, University Hospital Eppendorf, Hamburg, Germany
    J Invest Dermatol 114:1017-21. 2000
  5. ncbi request reprint Expression of insulin-like growth-factor-1 receptor (IGF-1R) in peripheral nerve sheath tumors in neurofibromatosis type 1
    R E Friedrich
    Maxillofacial Surgery Clinic, Eppendorf University Hospital, University of Hamburg, Germany
    Anticancer Res 27:2085-90. 2007
  6. doi request reprint High bone turnover and accumulation of osteoid in patients with neurofibromatosis 1
    S Seitz
    Center for Biomechanics and Skeletal Biology, University Medical Center Hamburg Eppendorf, Hamburg, Germany
    Osteoporos Int 21:119-27. 2010
  7. ncbi request reprint Oral lichen planus in patients with chronic liver diseases
    R E Friedrich
    Dept of Oral and Maxillofacial Surgery, University Hospital Hamburg Eppendorf, Martinistr 52, D 20246 Hamburg, Germany
    Infection 31:383-6. 2003
  8. ncbi request reprint Investigation about origin and spreading of neoendothelium in autologous arterial vessel replacement
    A Bartnick
    Department of Oral and Maxillofacial Surgery, Nordwestdeutsche Kieferklinik University of Hamburg, Germany
    In Vivo 17:619-24. 2003
  9. ncbi request reprint Expression of multi-drug resistance genes (mdr1, mrp1, bcrp) in primary oral squamous cell carcinoma
    R E Friedrich
    Klinik fur Mund, Kiefer und Gesichtschirurgie, Universitaetsklinikum Hamburg Eppendorf, Universitaet Hamburg, Germany
    In Vivo 18:133-47. 2004
  10. ncbi request reprint [Sonography as a training tool for screening of dubious midfacial fractures]
    M Heiland
    Kopf und Hautzentrum, Klinik und Poliklinik fur Zahn, Mund, Kiefer und Gesichtschirurgie Nordwestdeutsche Kieferklinik, Universitatsklinikum Hamburg Eppendorf
    Mund Kiefer Gesichtschir 8:244-9. 2004

Collaborators

Detail Information

Publications38

  1. ncbi request reprint Malignant peripheral nerve sheath tumors (MPNST) in NF1-affected children
    R E Friedrich
    Maxillofacial Surgery, University Hospital Hamburg Eppendorf, University of Hamburg, Hamburg, Germany
    Anticancer Res 27:1957-60. 2007
    ..At present there are only sparse data on MPNST in NF1-children. The aim of this study was to determine the outcome of children affected with NF1 who developed an MPNST...
  2. ncbi request reprint MRI growth patterns of plexiform neurofibromas in patients with neurofibromatosis type 1
    V F Mautner
    Section for Phakomatoses, Department of Maxillofacial Surgery, University Hospital Eppendorf, Hamburg, Germany
    Neuroradiology 48:160-5. 2006
    ..Classification of PNF may open new opportunities in clinical management, especially regarding decisions and options associated with surgical intervention...
  3. ncbi request reprint Clinical relevance of positron emission tomography and magnetic resonance imaging in the progression of internal plexiform neurofibroma in NF1
    V F Mautner
    Section of Phacomatoses, Maxillofacial Surgery, Eppendorf University Hospital, University of Hamburg, Germany
    Anticancer Res 27:1819-22. 2007
    ..Three tumors might represent an intermediate type between PNF and MPNST. Ablative surgery and complete histological work-up of specimens is the only way to clarify tumor status, thereby enabling provision of adequate local treatment...
  4. ncbi request reprint Mutations and allelic loss of the NF2 gene in neurofibromatosis 2-associated skin tumors
    L Kluwe
    Laboratory for Brain Tumor Biology, Department of Neurosurgery, University Hospital Eppendorf, Hamburg, Germany
    J Invest Dermatol 114:1017-21. 2000
    ..We also report that the detection rate of constitutional mutations was higher in patients with skin tumors (65%) than in patients without skin tumors (40%)...
  5. ncbi request reprint Expression of insulin-like growth-factor-1 receptor (IGF-1R) in peripheral nerve sheath tumors in neurofibromatosis type 1
    R E Friedrich
    Maxillofacial Surgery Clinic, Eppendorf University Hospital, University of Hamburg, Germany
    Anticancer Res 27:2085-90. 2007
    ..Factor and receptor are involved in the growth control of numerous physiological and pathological processes, including Schwann cell development...
  6. doi request reprint High bone turnover and accumulation of osteoid in patients with neurofibromatosis 1
    S Seitz
    Center for Biomechanics and Skeletal Biology, University Medical Center Hamburg Eppendorf, Hamburg, Germany
    Osteoporos Int 21:119-27. 2010
    ..Our data demonstrate that NF1 patients display high bone turnover and accumulation of osteoid and that supplementation of vitamin D has a beneficial effect on their BMD...
  7. ncbi request reprint Oral lichen planus in patients with chronic liver diseases
    R E Friedrich
    Dept of Oral and Maxillofacial Surgery, University Hospital Hamburg Eppendorf, Martinistr 52, D 20246 Hamburg, Germany
    Infection 31:383-6. 2003
    ..The possible increased risk of oral lichen planus (OLP) in patients with chronic liver diseases is a controversial issue...
  8. ncbi request reprint Investigation about origin and spreading of neoendothelium in autologous arterial vessel replacement
    A Bartnick
    Department of Oral and Maxillofacial Surgery, Nordwestdeutsche Kieferklinik University of Hamburg, Germany
    In Vivo 17:619-24. 2003
    ..The origin and the spread of the neoendothelium are unknown. Our study uses Von-Willebrand-protein, a product of endothelium cells, as a marker to obtain new information about the origin and spread of the new endothelial cells...
  9. ncbi request reprint Expression of multi-drug resistance genes (mdr1, mrp1, bcrp) in primary oral squamous cell carcinoma
    R E Friedrich
    Klinik fur Mund, Kiefer und Gesichtschirurgie, Universitaetsklinikum Hamburg Eppendorf, Universitaet Hamburg, Germany
    In Vivo 18:133-47. 2004
    ..Therefore, known resistance genes were investigated in oral squamous cell carcinoma (OSCC) and the results were compared with clinico-pathological findings...
  10. ncbi request reprint [Sonography as a training tool for screening of dubious midfacial fractures]
    M Heiland
    Kopf und Hautzentrum, Klinik und Poliklinik fur Zahn, Mund, Kiefer und Gesichtschirurgie Nordwestdeutsche Kieferklinik, Universitatsklinikum Hamburg Eppendorf
    Mund Kiefer Gesichtschir 8:244-9. 2004
    ..Patients with sonographically confirmed fractures can then be directly admitted to three-dimensional imaging, resulting in decreased radiation exposure since the conventional radiographs are omitted...
  11. ncbi request reprint Diagnosis, treatment and follow-up control in 124 patients with basal cell carcinoma of the maxillofacial region treated from 1992 to 1997
    R E Friedrich
    Department of Maxillofacial Surgery, Eppendorf University Hospital, University of Hamburg, Germany
    Anticancer Res 25:1693-7. 2005
    ..The aim of this study was to analyze diagnostic and therapeutic procedures and the outcome of patients treated for the most common malignant tumor of the facial skin, basal cell carcinoma...
  12. ncbi request reprint Navigation-assisted resection of a primary extraocular melanoma of the orbit
    R E Friedrich
    Maxillofacial Surgery, University Hospital Hamburg Eppendorf, University of Hamburg, Germany
    Anticancer Res 27:1799-803. 2007
    ..Conclusion: In the presented case with the incidental finding of orbital melanoma without invasion of the globe or orbital walls, navigation-assisted surgery supported the eye-saving operating procedures...
  13. ncbi request reprint Mutagenicity testing of mouthwash brands
    R E Friedrich
    Maxillofacial Surgery, Eppendorf University Hospital, Hamburg, Germany
    Anticancer Res 27:2091-8. 2007
    ....
  14. ncbi request reprint Potentials of ultrasound in the diagnosis of midfacial fractures*
    R E Friedrich
    Department of Oral and Maxillofacial Surgery, University Hospital Hamburg Eppendorf, Martinistrasse 52, 20246, Hamburg, Germany
    Clin Oral Investig 7:226-9. 2003
    ..In doubtful cases, an individual combination of conventional radiographs would be the next step. By this, an overall reduction of radiation exposure seems possible...
  15. ncbi request reprint Hypercementosis and odontogenic epithelial hyperplasia associated with a tooth root remnant mimicking a neoplasm. A case report
    J Zustin
    Institute of Pathology, University Medical Centre Hamburg, Eppendorf, Germany
    In Vivo 24:571-4. 2010
    ....
  16. ncbi request reprint [Involvement of the maxillary sinus in Langerhans cell histiocytosis]
    A Bartnick
    Mund Kiefer Gesichts Chirurgie, Nordwestdeutsche Kieferklinik, Universitatsklinikum Hamburg Eppendorf
    Mund Kiefer Gesichtschir 7:36-41. 2003
    ..LCH in the maxillary sinus is a rare occurrence. Our aim was to compare the different treatment alternatives available and to suggest a classification as well as a therapeutic regime...
  17. ncbi request reprint [Experimental and histomorphologic studies of healing processes of anastomoses of the carotid artery in the Wistar rat animal model with immunohistochemical imaging of collagen IV]
    A Bartnick
    Mund, Kiefer, Gesichtschirurgie, Nordwestdeutsche Kieferklinik, Universitatsklinikum Hamburg Eppendorf
    Mund Kiefer Gesichtschir 6:19-26. 2002
    ..We used a long-term animal experiment to gain a new understanding of histomorphological apposition of anastomosis and distribution of collagen IV...
  18. pmc Molecular study of frequency of mosaicism in neurofibromatosis 2 patients with bilateral vestibular schwannomas
    L Kluwe
    Laboratory for Brain Tumour Biology, Department of Neurosurgery, University Hospital Eppendorf, Hamburg, Germany
    J Med Genet 40:109-14. 2003
    ..429). Adding the 10 mosaic cases detected directly in blood specimens, we estimate the rate of mosaicism to be 24.8% (58/233) in our cohort of 233 NF2 founders with bilateral vestibular schwannomas...
  19. ncbi request reprint [Abnormalities of the maxillary sinus in type 1 neurofibromatosis]
    R E Friedrich
    Klinik fur Mund, Kiefer und Gesichtschirurgie, Nordwestdeutsche Kieferklinik, Universitatsklinikum Hamburg Eppendorf, Martinistrasse 52, 20246 Hamburg
    Mund Kiefer Gesichtschir 6:363-7. 2002
    ..The aim of this study was to determine the malformations of the maxillary sinus in neurofibromatosis type 1 patients (NF1)...
  20. ncbi request reprint [Acute temporomandibular joint arthritis after Lyme borreliosis]
    M Vesper
    Klinik fur Mund, Kiefer und Gesichtschirurgie, Universitatsklinikum Hamburg Eppendorf, Martinistrasse 52, 20246 Hamburg
    Mund Kiefer Gesichtschir 5:258-60. 2001
    ..The patient, a 49-year-old female, first came to our department in 1999. She showed the symptoms of a left temporomandibular joint infection...
  21. ncbi request reprint [Pneumatization of the zygomatic arch on pantomography]
    T Hofmann
    Klinik und Poliklinik fur Mund, Kiefer und Gesichtschirurgie, Nordwestdeutsche Kieferklinik, Universitatsklinikum Hamburg Eppendorf, Martinistrasse 52, 20246 Hamburg
    Mund Kiefer Gesichtschir 5:173-9. 2001
    ..The aim of this study was to determine the prevalence and characteristics of the ZACD in our outpatients...
  22. ncbi request reprint The expression pattern of collagen I in irradiated mandibular salivary glands of rats
    R E Friedrich
    Department of Oral and Maxillofacial Surgery, Eppendorf University Hospital, University of Hamburg, Hamburg, Germany
    Anticancer Res 23:927-30. 2003
    ..Collagen I (C-I) is a major component of the extracellular space. The aim of this study was to analyse the effects of irradiation on the distribution pattern of C-I in the salivary glands of rats...
  23. ncbi request reprint Limitations of B-scan ultrasound for diagnosing fractures of the mandibular condyle and ramus
    R E Friedrich
    Nordwestdeutsche Kieferklinik, Universitats Krankenhaus Eppendorf, Martinistr 52, 20246 Hamburg, Germany
    Clin Oral Investig 5:11-6. 2001
    ..Because of its low sensitivity and specificity, B-scan ultrasonography does not provide an alternative to X-ray diagnosis of mandibular condyle and ramus fractures...
  24. ncbi request reprint The presence of collagen III and IV in experimental microsurgical anastomoses of arteries
    R E Friedrich
    Department of Oral and Maxillofacial Surgery, Eppendorf University Hospital, University of Hamburg, Germany
    J Oral Maxillofac Surg 58:1125-8. 2000
    ..This study investigated the distribution of collagen III and IV in experimental microvascular anastomoses and correlated the findings with the quality of the healing process...
  25. pmc Vitamin D deficiency associated with number of neurofibromas in neurofibromatosis 1
    M Lammert
    Department of Maxillofacial Surgery, University Hospital Eppendorf, Hamburg, Germany
    J Med Genet 43:810-3. 2006
    ..572, p<0.00001). The occurrence of low serum vitamin D concentrations in people with NF1, especially those with many dermal neurofibromas, may provide new pathogenic insights and have important therapeutic implications...
  26. ncbi request reprint Hyperfractionated externally irradiated primary oral squamous cell carcinomas: vital tumor cells in resection specimens
    R E Friedrich
    Oral and Maxillofacial Surgery Clinic, Eppendorf University Hospital, University of Hamburg, Germany
    Anticancer Res 25:1707-9. 2005
    ..Indeed, the sequelae of surgery in an irradiated field are well known. The aim of this study was to determine vital tumor cells in the resection specimens of irradiated advanced stage OSCC in order to estimate the effect of radiotherapy...
  27. ncbi request reprint Growth type of plexiform neurofibromas in NF1 determined on magnetic resonance images
    R E Friedrich
    Department of OMFS, Eppendorf University Hospital, University of Hamburg, Germany
    Anticancer Res 23:949-52. 2003
    ..g. a displacing tumorous nerve developing in a large lumpy, non-invasive PNF. These categories might be used as a current guideline for medical advice, surgical treatment planning and medication trials...
  28. ncbi request reprint DNA-flow cytometry, DNA-image cytometry and proliferation index (MIB-5) in irradiated rat salivary glands and salivary gland tumors
    R E Friedrich
    Department of Oral and Maxillofacial Surgery, Eppendorf University Hospital, University of Hamburg, Germany
    In Vivo 18:213-22. 2004
    ..The aim of this study was to investigate cytogenetic alterations and to determine the proliferation index (PI) of SG of rats subjected to various total dosages of fractionated X-rays...
  29. ncbi request reprint Ki-67 proliferation-index (MIB-1) of neurofibromas in neurofibromatosis type 1 patients
    R E Friedrich
    Department of Oral and Maxillofacial Surgery, Eppendorf University Hospital, University of Hamburg, Martinistr 52, D 20246 Hamburg, Germany rfriedriguke uni hamburg de
    Anticancer Res 23:953-5. 2003
    ..g. the trigeminal branch plexiform neurofibromas, often require repeated surgical interventions. Therefore, the question whether partial resection is associated with alterations of the tumor type and proliferation is of great interest...
  30. ncbi request reprint [Detection of p53 mutation in mouth mucosa smears of patients with oral squamous epithelial carcinoma]
    M Giese
    , Kiefer- und Gesichtschirurgie (Nordwestdeutsche Kieferklinik, , Martinistr.52, 20246 Hamburg
    Mund Kiefer Gesichtschir 5:37-43. 2001
    ..In four cases the mutation was also found in the swab of normal mucosa. Our investigations revealed that swabs are a suitable method for obtaining material for the detection of gene mutations in oral squamous cell carcinomas...
  31. ncbi request reprint Malignant peripheral nerve sheath tumours in neurofibromatosis type 1: MRI supports the diagnosis of malignant plexiform neurofibroma
    V F Mautner
    Department of Neurology, Klinikum Nord Hamburg, Langenhorner Chaussee 560, 22419 Hamburg, Germany
    Neuroradiology 45:618-25. 2003
    ..All three asymptomatic patients with inhomogeneous lesions were shown to have MPNST...
  32. ncbi request reprint [The eruption times of permanent teeth in boys and girls in the Stormarn District, Schleswig-Holstein (Germany)]
    J S Wedl
    Zahnklinik der AOK Rheinland, Dusseldorf
    Anthropol Anz 63:189-97. 2005
    ..This first investigation on a population of Schleswig-Holstein revealed a change in the eruption sequence of permanent teeth. These findings are relevant for dental treatment planning and should be reconfirmed at certain intervals...
  33. ncbi request reprint Expression and distribution of basement membrane proteins in rat larynx and trachea following irradiation
    S Bartel-Friedrich
    Department of Otorhinolaryngology, University Hospital, Martin Luther University Halle Wittenberg, Magdeburger Strasse 12, 06097 Halle a d Saale, Germany
    Anticancer Res 23:877-84. 2003
    ..In this study, we set out to add to our knowledge on the phenotypic characterization of the radiogenic BM expression pattern in laryngo-tracheal tissues...
  34. ncbi request reprint [Biosurgical wound conditioning using maggot therapy and vacuum dressings following partial necrosis of a myocutaneous flap in the head and neck region following irradiation of this region]
    J S Wedl
    Mund Kiefer Gesichtschir 6:437-41. 2002
  35. ncbi request reprint Expression and distribution of cytokeratins and vimentin in rat larynx and trachea following irradiation
    S Bartel-Friedrich
    Department of Otorhinolaryngology, Phoniatrics and Pedaudiology Section, University Hospital, Martin Luther University Halle Wittenberg, Germany
    Anticancer Res 27:2059-69. 2007
    ..In this study, we investigated the phenotypic characterization of the normal integrity-supporting cytokeratins (CK) and vimentin following a clinically relevant IRR protocol in laryngeal-tracheal tissues...
  36. ncbi request reprint Transcription factor AP-2 is expressed in human Schwann cell-derived tumours
    A Harder
    Histopathology 49:441-3. 2006
  37. ncbi request reprint [Calcifying epithelial odontogenic tumor of the maxilla (Pindborg tumor)]
    L Li
    Klinik und Poliklinik fur Zahn, Mund, Kiefer und Gesichtschirurgie Nordwestdeutsche Kieferklinik, Universitat Hamburg
    Mund Kiefer Gesichtschir 8:46-50. 2004
    ..Local recurrences have rarely been reported but may be found even decades after primary treatment. Three years following surgical therapy there is no evidence of local recurrence. A long-term follow-up control is recommended...
  38. ncbi request reprint [Immunohistochemical detection of hormones in hypophyseal adenomas of the rat after fractionated irradiation]
    S Bartel-Friedrich
    , Nasen- und Ohrenheilkunde, Kopf- und Halschirurgie, , Halle a. d. S
    Laryngorhinootologie 80:257-62. 2001
    ..On the other hand, four of nine TM were null adenomas. Necropsies of the brain should be carried out routinely in irradiation studies of the skull...