Research Topics
Species | Lutz S FreudenbergSummaryAffiliation: University of Essen Country: Germany Publications
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Detail Information
Publications
Prognostic value of c-erbB-2 expression in papillary thyroid carcinomaL S Freudenberg
Department of Nuclear Medicine, University of Essen, Germany
Nuklearmedizin 44:179-82, 184. 2005..Objective of the study is to determine whether c-erbB-2 overexpression correlates with the clinical course...
PET versus PET/CT dual-modality imaging in evaluation of lung cancerLutz S Freudenberg
Department of Nuclear Medicine, University of Duisburg, Hufelandstrasse 55 D 45122, Essen, Germany
Radiol Clin North Am 45:639-44, v. 2007..Furthermore, an optimized PET/CT protocol for patients who have lung cancer is outlined...
124I-PET dosimetry in advanced differentiated thyroid cancer: therapeutic impactL S Freudenberg
Department of Nuclear Medicine, University of Duisburg Essen, Hufelandstr 55, 45122 Essen, Germany
Nuklearmedizin 46:121-8. 2007..This study evaluated the impact of (124)I-positron emission tomography (PET) dosimetry on post-primary surgery therapy in radioiodine-naïve patients with advanced differentiated thyroid cancer (DTC)...
[Evil radioactivity. Subjective perception of radioactivity in patients with thyroid disease prior to treatment with radioiodine]L S Freudenberg
Klinik für Nuklearmedizin, Universitatsklinikum Essen, Hufelandstrasse 55, 45122 Essen
Nuklearmedizin 45:229-34. 2006..From the interviews with the patients we evaluate as to how much radioactivity is accepted as an abstract term or as a benefit within the medical context...
Optimizing preoperative imaging in primary hyperparathyroidismLutz S Freudenberg
Department of Nuclear Medicine, University of Duisburg Essen, Hufelandstrasse 55, 45122 Essen, Germany
Langenbecks Arch Surg 391:551-6. 2006..The goal of the present prospective study was to determine the benefit of optimized imaging in a consistent patient population...
PET versus PET/CT dual-modality imaging in evaluation of lung cancerLutz S Freudenberg
Department of Nuclear Medicine, University of Duisburg, Hufelandstrasse 55 D 45122, Essen, Germany
Thorac Surg Clin 20:25-30. 2010..However, the benefits of anatometabolic imaging using FDG-PET/CT can only be fully exploited if optimized acquisition protocols are implemented...
Dual modality of 18F-fluorodeoxyglucose-positron emission tomography/computed tomography in patients with cervical carcinoma of unknown primaryLutz S Freudenberg
Clinic of Nuclear Medicine, University Hospital Essen, Essen, Germany
Med Princ Pract 14:155-60. 2005....
Combined metabolic and morphologic imaging in thyroid carcinoma patients with elevated serum thyroglobulin and negative cervical ultrasonography: role of 124I-PET/CT and FDG-PETL S Freudenberg
Department of Nuclear Medicine, University of Duisburg Essen, Hufelandstrasse 55, 45122 Essen, Germany
Eur J Nucl Med Mol Imaging 35:950-7. 2008..We assessed the lesion detection accuracy of 124I-PET alone, CT alone, (124)I-PET/CT, FDG-PET, and all these modalities combined...
FDG-PET/CT in re-staging of patients with lymphomaL S Freudenberg
Clinic and Policlinic for Nuclear Medicine, University of Essen, Essen, Germany
Eur J Nucl Med Mol Imaging 31:325-9. 2004..02) and has additional benefit over FDG-PET alone due to exact anatomical localisation. We conclude that FDG-PET/CT imaging is accurate in re-staging lymphoma and offers advantages over separate FDG-PET and CT imaging...
Diagnosis of labia metastasis by F-18 FDG PET and CT fusion imaging in sarcoma follow-upL S Freudenberg
Clinic and Policlinic for Nuclear Medicine, University of Essen, Germany
Clin Nucl Med 28:636-7. 2003..The presented case illustrates the usefulness of combined PET/CT fusion imaging to overcome some pitfalls of PET imaging alone (eg, differentiating malignant tumor from pooling of tracer in the genitourinary tract or contamination)...
Morphologic and functional changes in nontumorous liver tissue after radiofrequency ablation in an in vivo model: comparison of 18F-FDG PET/CT, MRI, ultrasound, and CTFlorian M Vogt
Department of Diagnostic and Interventional Radiology and Neuroradiology, University Duisburg Essen, Essen, Germany
J Nucl Med 48:1836-44. 2007..This study used MRI, CT, ultrasound, and (18)F-FDG PET/CT to assess the typical appearance of lesions in nontumorous animal liver tissue after radiofrequency ablation...
To enhance or not to enhance? 18F-FDG and CT contrast agents in dual-modality 18F-FDG PET/CTGerald Antoch
Department of Diagnostic and Interventional Radiology, University Hospital Essen, Essen, Germany
J Nucl Med 45:56S-65S. 2004..CT contrast agents and PET tracers do not compete but rather are complementary in combined PET/CT imaging...
Accuracy of whole-body dual-modality fluorine-18-2-fluoro-2-deoxy-D-glucose positron emission tomography and computed tomography (FDG-PET/CT) for tumor staging in solid tumors: comparison with CT and PETGerald Antoch
Department of Diagnostic and Interventional Radiology, University Hospital Essen, Hufelandstrasse 55, 45122 Essen, Germany
J Clin Oncol 22:4357-68. 2004..To assess the accuracy of positron emission tomography/computed tomography (PET/CT) when staging different malignant diseases...
Non-small cell lung cancer: dual-modality PET/CT in preoperative stagingGerald Antoch
Department of Diagnostic and Interventional Radiology, University Hospital Essen, Hufelandstrasse 55, 45122 Essen, Germany
Radiology 229:526-33. 2003..To determine the accuracy of dual-modality positron emission tomographic (PET)-computed tomographic (CT) imaging, as compared with PET alone and CT alone, in the staging of non-small cell lung cancer (NSCLC)...
Whole-body dual-modality PET/CT and whole-body MRI for tumor staging in oncologyGerald Antoch
Department of Diagnostic, University Hospital Essen, Essen, Germany
JAMA 290:3199-206. 2003..Magnetic resonance imaging (MRI) and a combined modality including positron emission tomography (PET) and computed tomography (CT) provide whole-body tumor staging in a single session...
Effect of oral contrast agents on computed tomography-based positron emission tomography attenuation correction in dual-modality positron emission tomography/computed tomography imagingGerald Antoch
Department of Diagnostic and Interventional Radiology, University Hospital Essen, Germany
Invest Radiol 38:784-9. 2003..To evaluate the effect of iodine- and barium-based contrast agents on the computed tomography (CT)-based positron emission tomography (PET) attenuation correction in dual-modality PET/CT...
Dual-modality FDG-PET/CT in follow-up of patients with recurrent iodine-negative differentiated thyroid cancerLutz S Freudenberg
Department of Nuclear Medicine, University of Duisburg Essen, Hufelandstrasse 55, 45122, Essen, Germany
Eur Radiol 17:3139-47. 2007..Accurate fusion of functional and morphologic data by FDG-PET/CT improves the staging accuracy of patients with suspected recurrence of iodine-negative DTC. This has an impact on patient management in a substantial number of patients...
Whole-body positron emission tomography-CT: optimized CT using oral and IV contrast materialsGerald Antoch
Department of Diagnostic and Interventional Radiology, University Hospital Essen, Hufelandstr. 55, 45122 Essen, Germany
AJR Am J Roentgenol 179:1555-60. 2002..702). CONCLUSION: Our whole-body PET-CT protocol provided good vascular and intestinal enhancement without compromising PET quality, leading to a potential improvement in the diagnostic capacity of the combined PET-CT examination...
Positron emission tomography/computed tomography improves diagnostics of inflammatory arteritisKnut Kroger
Department of Angiology, University Hospital Essen, Hufelandstrasse 55, 45122, Essen, Germany
Heart Vessels 20:179-83. 2005..The advantages in differentiation of vessel wall structures compared with PET or CT alone are pointed out...
Breast cancer staging in a single session: whole-body PET/CT mammographyTill A Heusner
Department of Diagnostic and Interventional Radiology and Neuroradiology, University Hospital Essen, University at Duisburg Essen, Essen, Germany
J Nucl Med 49:1215-22. 2008....
Focal tracer uptake: a potential artifact in contrast-enhanced dual-modality PET/CT scansGerald Antoch
Department of Diagnostic and Interventional Radiology, University Hospital Essen, Essen, Germany
J Nucl Med 43:1339-42. 2002..This study was performed to evaluate a possible artifact related to the administration of intravascular contrast agent in dual-modality PET/CT imaging...
Acquisition protocol considerations for combined PET/CT imagingThomas Beyer
Department of Nuclear Medicine, University Hospital Essen, Essen, Germany
J Nucl Med 45:25S-35S. 2004..Only then will the potential diagnostic benefit of this new imaging modality be explored fully...
Disseminated iodine-avid lung metastases in differentiated thyroid cancer: a challenge to 124I PETLutz S Freudenberg
Department of Nuclear Medicine, University of Duisburg Essen, Hufelandstrasse 55, Essen, Germany
Eur J Nucl Med Mol Imaging 35:502-8. 2008..This study assessed the ability of visual and quantitative 124-iodine positron emission tomography ((124)I PET) data to detect disseminated iodine-avid lung metastases (DILM) of differentiated thyroid cancer (DTC)...
Assessment of liver tissue after radiofrequency ablation: findings with different imaging proceduresGerald Antoch
Department of Diagnostic and Interventional Radiology, University Hospital Essen, Essen, Germany
J Nucl Med 46:520-5. 2005..Our goal was to assess the typical appearance of normal liver tissue immediately after radiofrequency ablation (RF-ablation) when imaged with contrast-enhanced ultrasound, CT, MRI, 18F-FDG PET, and PET/CT...
Positron emission tomography/computed tomography--imaging protocols, artifacts, and pitfallsAndreas Bockisch
Departments of Nuclear Medicine, University Hospital, Essen, Germany
Mol Imaging Biol 6:188-99. 2004....
Clinical applications of 124I-PET/CT in patients with differentiated thyroid cancerLutz S Freudenberg
Department of Nuclear Medicine, University Hospital Essen, Essen, Germany
Eur J Nucl Med Mol Imaging 38:S48-56. 2011..This review summarizes the clinical data on (124)I-PET/CT in patients with DTC, and addresses future prospects...
Comparison of PET, CT, and dual-modality PET/CT imaging for monitoring of imatinib (STI571) therapy in patients with gastrointestinal stromal tumorsGerald Antoch
Department of Diagnostic and Interventional Radiology, University of Essen, Essen, Germany
J Nucl Med 45:357-65. 2004..This study was implemented to compare the value of PET, CT, and dual-modality PET/CT imaging for assessing gastrointestinal stromal tumor (GIST) response to imatinib therapy...
Thyroid cancer in childhood: management strategy, including dosimetry and long-term resultsMarkus Luster
Department of Nuclear Medicine, University of Wurzburg, Germany
Hormones (Athens) 6:269-78. 2007..These considerations have led to individualized "tailored" therapeutic approaches based on prior risk stratification. This article mainly deals with novel nuclear medicine concepts for dosing regimens in radioiodine therapy...
Hybrid imaging by SPECT/CT and PET/CT: proven outcomes in cancer imagingAndreas Bockisch
Department of Nuclear Medicine, University Hospital of Essen, Essen, Germany
Semin Nucl Med 39:276-89. 2009..These systems will lead medical imaging to new horizons, and they will offer the virtually unlimited potential of simultaneously acquiring morphologic, functional, and molecular information about the living human body...
Pre-therapeutic blood dosimetry in patients with differentiated thyroid carcinoma using 124-iodine: predicted blood doses correlate with changes in blood cell counts after radioiodine therapy and depend on modes of TSH stimulation and number of preceding Verena Hartung-Knemeyer
Department of Nuclear Medicine, Medical Faculty, University Duisburg Essen, Hufelandstrase 55, 45147, Essen, Germany
Ann Nucl Med 26:723-9. 2012..Moreover, the influence of different modes of TSH stimulation and the number of preceding radioiodine therapies on the blood dose were assessed...
Variations in clinical PET/CT operations: results of an international survey of active PET/CT usersThomas Beyer
Department of Nuclear Medicine, University Hospital Essen, Essen, Germany
J Nucl Med 52:303-10. 2011..This study gathered information about clinical PET/CT operations worldwide to help guide discussions on the use and standardization of clinical PET/CT...
Images in vascular medicine. Diagnosis of giant cell arteritis with PET/CTGerald Antoch
Department of Diagnostic and Interventional Radiology, University Hospital Essen, Essen, Germany
Vasc Med 8:281-2. 2003
An approach towards problem-based learning in virtual spaceLutz S Freudenberg
Universitatsklinikum Essen, Klinik für Nuklearmedizin, Essen, Deutschland
GMS Z Med Ausbild 27:Doc73. 2010..This has initiated discussions about opening our PBL concept to a wider audience within the university and beyond the Nuclear Medicine specialty...
Subjective perception of radiation riskLutz S Freudenberg
Department of Nuclear Medicine, University Hospital Essen, Essen, Germany
J Nucl Med 52:29S-35S. 2011..Although the choice and timing of imaging examinations should always outweigh the risk that secondary illness will develop, the patients' concerns still must be alleviated...
Whole-body MRI using a rolling table platform for the detection of bone metastasesThomas C Lauenstein
Department of Diagnostic Radiology, University Hospital Essen, Hufelandstrasse 55, 45122 Essen, Germany
Eur Radiol 12:2091-9. 2002..The MRI screening for bone metastases correlated well with bone scintigraphy. Use of the rolling table platform permits rapid imaging based on three different contrast mechanisms of the entire skeletal system...
