P Franke

Summary

Affiliation: University of Bonn
Country: Germany

Publications

  1. ncbi request reprint Human delta-opioid receptor gene and susceptibility to heroin and alcohol dependence
    P Franke
    Department of Psychiatry, University of Bonn, Bonn, Germany
    Am J Med Genet 88:462-4. 1999
  2. ncbi request reprint Genotype-phenotype relationship in female carriers of the premutation and full mutation of FMR-1
    P Franke
    Department of Psychiatry, University of Bonn, Germany
    Psychiatry Res 80:113-27. 1998
  3. ncbi request reprint Nonreplication of association between mu-opioid-receptor gene (OPRM1) A118G polymorphism and substance dependence
    P Franke
    Department of Psychiatry University of Bonn, Germany
    Am J Med Genet 105:114-9. 2001
  4. ncbi request reprint Differential memory span--abnormal lateralization pattern in schizophrenic patients and their siblings?
    P Franke
    Department of Psychiatry, University of Bonn, Germany
    Int J Psychophysiol 34:303-11. 1999
  5. ncbi request reprint Excess of high activity monoamine oxidase A gene promoter alleles in female patients with panic disorder
    J Deckert
    Department of Psychiatry, University of Wurzburg, Fuchsleinstrasse 15, 97080 Wurzburg, Germany, Istituto di Ricovero e Cura a Carattere Scientifico H San Raffaele, DSNP, Via Prinetti 29, 20127 Milan, Italy
    Hum Mol Genet 8:621-4. 1999
  6. ncbi request reprint Systematic mutation screening and association study of the A1 and A2a adenosine receptor genes in panic disorder suggest a contribution of the A2a gene to the development of disease
    J Deckert
    Department of Psychiatry, University of Wurzburg, Germany
    Mol Psychiatry 3:81-5. 1998
  7. ncbi request reprint Norepinephrine transporter gene (NET) variants in patients with panic disorder
    P G Sand
    Department of Psychiatry, University of Wurzburg, Füchsleinstrazze 15, D 97080, Wurzburg, Germany
    Neurosci Lett 333:41-4. 2002
  8. ncbi request reprint Human nuclear transcription factor gene CREM: genomic organization, mutation screening, and association analysis in panic disorder
    K Domschke
    Department of Psychiatry, University of Munster, Munster, Germany
    Am J Med Genet B Neuropsychiatr Genet 117:70-8. 2003
  9. ncbi request reprint Association study of the low-activity allele of catechol-O-methyltransferase and alcoholism using a family-based approach
    T Wang
    Institute of Human Genetics, University of Bonn, Wilhelmstr 31, 53111 Bonn, Germany
    Mol Psychiatry 6:109-11. 2001
  10. ncbi request reprint Exonic variants of the GABA(B) receptor gene and panic disorder
    P G Sand
    Department of Psychiatry, University of Wurzburg, Germany
    Psychiatr Genet 10:191-4. 2000

Detail Information

Publications19

  1. ncbi request reprint Human delta-opioid receptor gene and susceptibility to heroin and alcohol dependence
    P Franke
    Department of Psychiatry, University of Bonn, Bonn, Germany
    Am J Med Genet 88:462-4. 1999
    ..Our results, therefore, do not support an association between genetic variation of the delta-opioid receptor and addictive behavior in man...
  2. ncbi request reprint Genotype-phenotype relationship in female carriers of the premutation and full mutation of FMR-1
    P Franke
    Department of Psychiatry, University of Bonn, Germany
    Psychiatry Res 80:113-27. 1998
    ..Correlations between size of CGG repeat and IQ as well as CGG and age of onset of axis I diagnosis were non-significant. IQ of subjects had no impact on presence or absence of axis I and/or axis II diagnoses...
  3. ncbi request reprint Nonreplication of association between mu-opioid-receptor gene (OPRM1) A118G polymorphism and substance dependence
    P Franke
    Department of Psychiatry University of Bonn, Germany
    Am J Med Genet 105:114-9. 2001
    ..In addition, there was no significant association between the endophenotype of the individuals under study (e.g., comorbidity, severity of illness) and a particular genotype of OPRM1...
  4. ncbi request reprint Differential memory span--abnormal lateralization pattern in schizophrenic patients and their siblings?
    P Franke
    Department of Psychiatry, University of Bonn, Germany
    Int J Psychophysiol 34:303-11. 1999
    ....
  5. ncbi request reprint Excess of high activity monoamine oxidase A gene promoter alleles in female patients with panic disorder
    J Deckert
    Department of Psychiatry, University of Wurzburg, Fuchsleinstrasse 15, 97080 Wurzburg, Germany, Istituto di Ricovero e Cura a Carattere Scientifico H San Raffaele, DSNP, Via Prinetti 29, 20127 Milan, Italy
    Hum Mol Genet 8:621-4. 1999
    ....
  6. ncbi request reprint Systematic mutation screening and association study of the A1 and A2a adenosine receptor genes in panic disorder suggest a contribution of the A2a gene to the development of disease
    J Deckert
    Department of Psychiatry, University of Wurzburg, Germany
    Mol Psychiatry 3:81-5. 1998
    ..Replication studies in independent samples with nuclear families applying the transmission disequilibrium test (TDT) are warranted...
  7. ncbi request reprint Norepinephrine transporter gene (NET) variants in patients with panic disorder
    P G Sand
    Department of Psychiatry, University of Wurzburg, Füchsleinstrazze 15, D 97080, Wurzburg, Germany
    Neurosci Lett 333:41-4. 2002
    ..Except for a silent substitution (G1287A), overall frequencies of variant alleles were low (< or =0.016). None of the variants under study was found to be associated with PD regardless of an additional diagnosis of agoraphobia...
  8. ncbi request reprint Human nuclear transcription factor gene CREM: genomic organization, mutation screening, and association analysis in panic disorder
    K Domschke
    Department of Psychiatry, University of Munster, Munster, Germany
    Am J Med Genet B Neuropsychiatr Genet 117:70-8. 2003
    ..Functional analysis of the observed CREM P 2 promoter polymorphism as well as studies in independent panic disorder samples are necessary...
  9. ncbi request reprint Association study of the low-activity allele of catechol-O-methyltransferase and alcoholism using a family-based approach
    T Wang
    Institute of Human Genetics, University of Bonn, Wilhelmstr 31, 53111 Bonn, Germany
    Mol Psychiatry 6:109-11. 2001
    ..83, P = 0.028). Our results provide further evidence for an involvement of the COMT low-activity allele in the development of alcoholism and demonstrate the need for further studies in large samples of alcoholic patients...
  10. ncbi request reprint Exonic variants of the GABA(B) receptor gene and panic disorder
    P G Sand
    Department of Psychiatry, University of Wurzburg, Germany
    Psychiatr Genet 10:191-4. 2000
    ..There was no indication of an increased vulnerability to panic disorder or agoraphobia with respect to the allelic variants under study...
  11. ncbi request reprint Polymorphic MAO-A and 5-HT-transporter genes: analysis of interactions in panic disorder
    P Sand
    Department of Psychiatry, University of Wurzburg, Fuchsleinstr 15, 97080 Wurzburg, Germany
    World J Biol Psychiatry 1:147-50. 2000
    ..There was no significant difference in odds ratios, suggesting that the observed increase of genetic liability by the long MAO-A gene promoter allele is not modified by the 5-HTT gene promoter polymorphism...
  12. ncbi request reprint Rgs 2 gene polymorphisms as modulators of anxiety in humans?
    A Leygraf
    Laboratory of Molecular Psychiatry, Department of Psychiatry, University of Munster, Munster, Germany
    J Neural Transm 113:1921-5. 2006
    ..01 and 0.03). This points towards a functional polymorphism at the 3' end of the gene. Our results support the hypothesis that variations of the Rgs2 gene play a role also for the development of anxiety in humans...
  13. ncbi request reprint [Psychiatric comorbidity in risk groups of opioid addiction: a comparison between opioid dependent and non-opioid dependent prisoners (in jail due to the German narcotics law)]
    P Franke
    Klinik und Poliklinik für Psychiatrie und Psychotherapie der Universität Bonn
    Fortschr Neurol Psychiatr 71:37-44. 2003
    ..In general, the sample of prisoners investigated here, was characterized by a high frequency of psychiatric disorders including substance dependence...
  14. ncbi request reprint Support for allelic association of a polymorphic site in the promoter region of the serotonin transporter gene with risk for alcohol dependence
    D Lichtermann
    Department of Psychiatry and Medical Psychology, University Medical School of Pecs, Hungary
    Am J Psychiatry 157:2045-7. 2000
    ..The authors sought additional evidence for this association from a family-based study...
  15. ncbi request reprint Subcortical correlates of craving in recently abstinent alcoholic patients
    F Schneider
    Department of Psychiatry and Psychotherapy, University of Bonn, Germany
    Am J Psychiatry 158:1075-83. 2001
    ..This study investigated functional cerebral correlates of craving in alcoholic patients and examined the state/trait characteristics of the regional cerebral network implicated in craving...
  16. ncbi request reprint Pharmacogenomics and addiction to opiates
    D Lichtermann
    Department of Psychiatry, University of Bonn, Sigmund Freud Str 25, D 53105, Bonn, Germany
    Eur J Pharmacol 410:269-279. 2000
    ..The present state of pharmacogenomic and pharmacogenetic studies in animals and humans with respect to opiate addiction is reviewed in this paper...
  17. ncbi request reprint Special feature: family-genetic research strategies for personality disorders
    W Maier
    Department of Psychiatry, University of Bonn, FRG
    J Pers Disord 12:262-76. 1998
    ..Gene-oriented approaches seem to be particularly promising. This strategy is illustrated for personality disorders in obligate carriers of mutations in the fragile-X gene...
  18. ncbi request reprint Association study of serotonin-2A receptor gene polymorphism and panic disorder in patients from Canada and Germany
    C Rothe
    Department of Psychiatry, University of Ottawa and the University of Ottawa Institute of Mental Health Research, Royal Ottawa Hospital, Ottawa, Canada
    Neurosci Lett 363:276-9. 2004
    ..Our data suggest thus that this polymorphism is unlikely to play a major role in the pathogenesis of panic disorder...
  19. ncbi request reprint The reliability of the SADS-LA in a family study setting
    M Leboyer
    INSERM, , , Paris, France
    Eur Arch Psychiatry Clin Neurosci 241:165-9. 1991
    ..g. bipolar II disorder) and identification of minor disorders was less reliable. The implications of these findings in phenotype identification during family studies in psychiatry are discussed...