Konrad F Frank

Summary

Affiliation: University of Cologne
Country: Germany

Publications

  1. ncbi request reprint Modulation of SERCA: implications for the failing human heart
    Konrad F Frank
    Laboratory of Muscle Research and Molecular Cardiology, Clinic III for Internal Medicine, University of Cologne, Joseph Stelzmann Str 9, 50924 Kö1n, Germany
    Basic Res Cardiol 97:I72-8. 2002
  2. ncbi request reprint Diabetes-related defects in sarcoplasmic Ca2+ release are prevented by inactivation of G(alpha)11 and G(alpha)q in murine cardiomyocytes
    Dieter Paul Hoyer
    Department of Internal Medicine III, University of Cologne, Kerpener Str 62, 50937 Cologne, Germany
    Mol Cell Biochem 341:235-44. 2010
  3. ncbi request reprint Sarcoplasmic Ca2+ release is prolonged in nonfailing myocardium of diabetic patients
    Hannes Reuter
    Laboratory of Muscle Research and Molecular Cardiology, Department III of Internal Medicine, University of Cologne, Kerpener Str 62, 50937 Cologne, Germany
    Mol Cell Biochem 308:141-9. 2008
  4. ncbi request reprint Sarcoplasmic reticulum Ca2+-ATPase modulates cardiac contraction and relaxation
    Konrad F Frank
    Clinic III of Internal Medicine, Laboratory of Muscle Research and Molecular Cardiology, University of Cologne, Cologne, Germany
    Cardiovasc Res 57:20-7. 2003
  5. ncbi request reprint Calcium and the failing heart: phospholamban, good guy or bad guy?
    Robert H G Schwinger
    Laboratory of Muscle Research and Molecular Cardiology, Department of Internal Medicine III, Joseph Stelzmannstrasse, 50924 Köln, Germany
    Sci STKE 2003:pe15. 2003
  6. ncbi request reprint Pneumomediastinum and striking family history: uncommon case of Birt-Hogg-Dubé syndrome
    Guido Michels
    Department III of Internal Medicine, University of Cologne, Germany
    Intern Med 51:2007-9. 2012
  7. ncbi request reprint Enhanced myocyte contractility and Ca2+ handling in a calcineurin transgenic model of heart failure
    Guoxiang Chu
    Department of Pharmacology and Cell Biophysics, University of Cincinnati College of Medicine, 231 Albert B Sabin Way, OH 45267 0575, USA
    Cardiovasc Res 54:105-16. 2002
  8. ncbi request reprint Combined phospholamban ablation and SERCA1a overexpression result in a new hyperdynamic cardiac state
    Wen Zhao
    Department of Pharmacology and Cell Biophysics, University of Cincinnati, College of Medicine, 231 Albert Sabin Way, Cincinnati, OH 45267 0575, USA
    Cardiovasc Res 57:71-81. 2003
  9. ncbi request reprint [Reverse remodeling of the intracellular Ca(2+)-homeostasis: new concepts of pathophysiology and therapy of heart failure]
    Klara Brixius
    Labor für Herzmuskelphysiologie und Molekulare Kardiologie, Klinik III fur Innere Medizin, Koln
    Wien Med Wochenschr 156:209-15. 2006

Collaborators

Detail Information

Publications9

  1. ncbi request reprint Modulation of SERCA: implications for the failing human heart
    Konrad F Frank
    Laboratory of Muscle Research and Molecular Cardiology, Clinic III for Internal Medicine, University of Cologne, Joseph Stelzmann Str 9, 50924 Kö1n, Germany
    Basic Res Cardiol 97:I72-8. 2002
    ..This review summarizes recent advances in the understanding how SERCA is modulated under physiological and pathophysiological conditions...
  2. ncbi request reprint Diabetes-related defects in sarcoplasmic Ca2+ release are prevented by inactivation of G(alpha)11 and G(alpha)q in murine cardiomyocytes
    Dieter Paul Hoyer
    Department of Internal Medicine III, University of Cologne, Kerpener Str 62, 50937 Cologne, Germany
    Mol Cell Biochem 341:235-44. 2010
    ..6, annexin A7, and sorcin...
  3. ncbi request reprint Sarcoplasmic Ca2+ release is prolonged in nonfailing myocardium of diabetic patients
    Hannes Reuter
    Laboratory of Muscle Research and Molecular Cardiology, Department III of Internal Medicine, University of Cologne, Kerpener Str 62, 50937 Cologne, Germany
    Mol Cell Biochem 308:141-9. 2008
    ..This defective Ca(2+) release may represent an early stage of ventricular dysfunction in type 2 diabetes and would favor the abnormal response to exercise frequently observed in asymptomatic diabetic patients...
  4. ncbi request reprint Sarcoplasmic reticulum Ca2+-ATPase modulates cardiac contraction and relaxation
    Konrad F Frank
    Clinic III of Internal Medicine, Laboratory of Muscle Research and Molecular Cardiology, University of Cologne, Cologne, Germany
    Cardiovasc Res 57:20-7. 2003
    ....
  5. ncbi request reprint Calcium and the failing heart: phospholamban, good guy or bad guy?
    Robert H G Schwinger
    Laboratory of Muscle Research and Molecular Cardiology, Department of Internal Medicine III, Joseph Stelzmannstrasse, 50924 Köln, Germany
    Sci STKE 2003:pe15. 2003
    ..This Perspective discusses new advances in our understanding of the role of phospholamban in intracellular Ca(2+) handling and the development of human and murine cardiomyopathies...
  6. ncbi request reprint Pneumomediastinum and striking family history: uncommon case of Birt-Hogg-Dubé syndrome
    Guido Michels
    Department III of Internal Medicine, University of Cologne, Germany
    Intern Med 51:2007-9. 2012
    ..We report a patient with pneumomediastinum and cervico-facial emphysema after severe coughing without pneumothorax, skin lesions or renal tumour, but a striking family history of lung abnormalities...
  7. ncbi request reprint Enhanced myocyte contractility and Ca2+ handling in a calcineurin transgenic model of heart failure
    Guoxiang Chu
    Department of Pharmacology and Cell Biophysics, University of Cincinnati College of Medicine, 231 Albert B Sabin Way, OH 45267 0575, USA
    Cardiovasc Res 54:105-16. 2002
    ..We examined whether defects in cardiomyocyte Ca2+ handling properties contribute to the impaired cardiac function in calcineurin transgenic mice...
  8. ncbi request reprint Combined phospholamban ablation and SERCA1a overexpression result in a new hyperdynamic cardiac state
    Wen Zhao
    Department of Pharmacology and Cell Biophysics, University of Cincinnati, College of Medicine, 231 Albert Sabin Way, Cincinnati, OH 45267 0575, USA
    Cardiovasc Res 57:71-81. 2003
    ..The aim of the present study was to determine whether a combination of these two genetic manipulations may lead to further augmentation of cardiac function...
  9. ncbi request reprint [Reverse remodeling of the intracellular Ca(2+)-homeostasis: new concepts of pathophysiology and therapy of heart failure]
    Klara Brixius
    Labor für Herzmuskelphysiologie und Molekulare Kardiologie, Klinik III fur Innere Medizin, Koln
    Wien Med Wochenschr 156:209-15. 2006
    ..In addition, new therapeutic options will be introduced which may be of importance for the treatment of heart failure patients...