Carsten Framme

Summary

Affiliation: University of Regensburg
Country: Germany

Publications

  1. doi request reprint Clinical evaluation of experimentally induced choroidal neovascularizations in pigmented rabbits by subretinal injection of lipid hydroperoxide and consecutive preliminary photodynamic treatment with Tookad
    Carsten Framme
    Medical Laser Center Lübeck, Lubeck, Germany
    Ophthalmologica 222:254-64. 2008
  2. ncbi request reprint [Central retinal artery occlusion. Importance of selective intra-arterial fibrinolysis]
    C Framme
    Augenklinik und Poliklinik, Klinikum, Universitat Regensburg, Franz Josef Strauss Allee 11, 93042 Regensburg
    Ophthalmologe 98:725-30. 2001
  3. ncbi request reprint Online autofluorescence measurements during selective RPE laser treatment
    Carsten Framme
    Medical Laser Center Lübeck, Lubeck, Germany
    Graefes Arch Clin Exp Ophthalmol 242:863-9. 2004
  4. ncbi request reprint Temperature dependent fluorescence of A2-E, the main fluorescent lipofuscin component in the RPE
    Carsten Framme
    Medical Laser Center Luebeck, Luebeck, Germany
    Curr Eye Res 29:287-91. 2004
  5. ncbi request reprint Fundus autofluorescence in acute and chronic-recurrent central serous chorioretinopathy
    Carsten Framme
    University Eye Hospital Regensburg, Regensburg, Germany
    Acta Ophthalmol Scand 83:161-7. 2005
  6. ncbi request reprint [Selective RPE laser treatment with a scanned cw laser beam in rabbits]
    C Framme
    Wellman Center for Photomedicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA
    Ophthalmologe 102:491-6. 2005
  7. doi request reprint Investigation of selective retina treatment (SRT) by means of 8 ns laser pulses in a rabbit model
    Carsten Framme
    University Eye Hospital Regensburg, 93042, Germany
    Lasers Surg Med 40:20-7. 2008
  8. ncbi request reprint [Unilateral macular hemorrhage of unknown origin]
    C Framme
    Klinik und Poliklinik für Augenheilkunde, Klinikum der Universitat Regensburg, Franz Josef Strauss Allee 11, 93042 Regensburg
    Ophthalmologe 104:983-4. 2007
  9. ncbi request reprint Comparison of reduced and standard light application in photodynamic therapy of the eye in two rabbit models
    C Framme
    Medical Laser Center Luebeck, Luebeck, Germany
    Graefes Arch Clin Exp Ophthalmol 244:773-81. 2006
  10. ncbi request reprint [Cost recovery for the treatment of retinal and vitreal diseases by pars plana vitrectomy under the German DRG system]
    C Framme
    Klinik und Poliklinik für Augenheilkunde, Klinikum der Universitat Regensburg, 93042, Regensburg
    Ophthalmologe 104:866-74. 2007

Detail Information

Publications44

  1. doi request reprint Clinical evaluation of experimentally induced choroidal neovascularizations in pigmented rabbits by subretinal injection of lipid hydroperoxide and consecutive preliminary photodynamic treatment with Tookad
    Carsten Framme
    Medical Laser Center Lübeck, Lubeck, Germany
    Ophthalmologica 222:254-64. 2008
    ..It was our aim to reevaluate and verify the method of inducing experimental CNVs in rabbits using subretinally injected linoleic acid hydroperoxide (LHP) as proposed by Tamai et al. and to use it for experimental PDT...
  2. ncbi request reprint [Central retinal artery occlusion. Importance of selective intra-arterial fibrinolysis]
    C Framme
    Augenklinik und Poliklinik, Klinikum, Universitat Regensburg, Franz Josef Strauss Allee 11, 93042 Regensburg
    Ophthalmologe 98:725-30. 2001
    ..The importance of IF was evaluated in 62 patients with central retinal artery occlusion and in addition the risk spectrum for this disease was considered...
  3. ncbi request reprint Online autofluorescence measurements during selective RPE laser treatment
    Carsten Framme
    Medical Laser Center Lübeck, Lubeck, Germany
    Graefes Arch Clin Exp Ophthalmol 242:863-9. 2004
    ..Since the green treatment laser beam could also be used for AF excitation, the aim of this study was to evaluate whether absolute measurements of AF can be performed, and also possible changes in AF detected, online during SRT...
  4. ncbi request reprint Temperature dependent fluorescence of A2-E, the main fluorescent lipofuscin component in the RPE
    Carsten Framme
    Medical Laser Center Luebeck, Luebeck, Germany
    Curr Eye Res 29:287-91. 2004
    ....
  5. ncbi request reprint Fundus autofluorescence in acute and chronic-recurrent central serous chorioretinopathy
    Carsten Framme
    University Eye Hospital Regensburg, Regensburg, Germany
    Acta Ophthalmol Scand 83:161-7. 2005
    ..The purpose of this study was to compare AF patterns in acute and chronic-recurrent CSC and to evaluate the potential value of AF as a non-invasive monitoring tool...
  6. ncbi request reprint [Selective RPE laser treatment with a scanned cw laser beam in rabbits]
    C Framme
    Wellman Center for Photomedicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA
    Ophthalmologe 102:491-6. 2005
    ..It was the goal of this study to show, if selectivity could also be achieved using a conventional green cw-laser by scanning the beam across the retina during irradiation...
  7. doi request reprint Investigation of selective retina treatment (SRT) by means of 8 ns laser pulses in a rabbit model
    Carsten Framme
    University Eye Hospital Regensburg, 93042, Germany
    Lasers Surg Med 40:20-7. 2008
    ....
  8. ncbi request reprint [Unilateral macular hemorrhage of unknown origin]
    C Framme
    Klinik und Poliklinik für Augenheilkunde, Klinikum der Universitat Regensburg, Franz Josef Strauss Allee 11, 93042 Regensburg
    Ophthalmologe 104:983-4. 2007
  9. ncbi request reprint Comparison of reduced and standard light application in photodynamic therapy of the eye in two rabbit models
    C Framme
    Medical Laser Center Luebeck, Luebeck, Germany
    Graefes Arch Clin Exp Ophthalmol 244:773-81. 2006
    ....
  10. ncbi request reprint [Cost recovery for the treatment of retinal and vitreal diseases by pars plana vitrectomy under the German DRG system]
    C Framme
    Klinik und Poliklinik für Augenheilkunde, Klinikum der Universitat Regensburg, 93042, Regensburg
    Ophthalmologe 104:866-74. 2007
    ..It was the aim of this study to check the cost recovery at a University Eye Hospital for the surgical treatment of retinal and vitreal diseases by pars plana vitrectomy (ppV), which are included in DRGs C03Z and C17Z...
  11. doi request reprint [Cost calculations for treating penetrating eye injuries within the DRG C01Z at a university eye hospital]
    C Framme
    Klinik und Poliklinik für Augenheilkunde, Klinikum der Universitat Regensburg, Franz Josef Strauss Allee 11, 93042, Regensburg, Germany
    Ophthalmologe 105:936-42. 2008
    ..It was the aim to check the cost recovery for the surgical treatment of penetrating eye injuries at a university eye hospital...
  12. doi request reprint [Basic principles and clinical application of retinal laser therapy]
    C Framme
    Klinik und Poliklinik für Augenheilkunde, Universitat Regensburg
    Klin Monbl Augenheilkd 225:259-68. 2008
    ..g., for retinopexia or macular treatments as well as for diabetic retinopathies. Specific laser strategies such as the selective laser treatment of the RPE (SRT) or the transpupillary thermotherapy (TTT) are presented and discussed...
  13. ncbi request reprint Structural changes of the retina after conventional laser photocoagulation and selective retina treatment (SRT) in spectral domain OCT
    Carsten Framme
    University Eye Hospital, Regensburg, Germany
    Curr Eye Res 34:568-79. 2009
    ..This article aims to investigate the value of SD-OCT in comparing laser lesions produced by conventional laser photocoagulation and selective retina treatment (SRT)...
  14. doi request reprint [Prioritisation in the German health care system--an issue in ophthalmology?]
    C Framme
    Klinik und Poliklinik für Augenheilkunde, Universitat Regensburg, Regensburg
    Klin Monbl Augenheilkd 226:154-60. 2009
    ....
  15. pmc Autofluorescence imaging after selective RPE laser treatment in macular diseases and clinical outcome: a pilot study
    C Framme
    University Eye Hospital Regensburg, Germany Medical Laser Center, Luebeck, Germany
    Br J Ophthalmol 86:1099-106. 2002
    ..Additionally, the clinical course of patients with various macular diseases was evaluated...
  16. doi request reprint Comparison of threshold irradiances and online dosimetry for selective retina treatment (SRT) in patients treated with 200 nanoseconds and 1.7 microseconds laser pulses
    Carsten Framme
    University Eye Hospital Regensburg, Franz Josef Strauss Allee 11, Regensburg, Germany
    Lasers Surg Med 40:616-24. 2008
    ..7 microseconds in duration. It was our purpose to evaluate the principle feasibility of SRT with shorter 200 nanoseconds laser pulses in patients...
  17. ncbi request reprint Influence of pulse duration and pulse number in selective RPE laser treatment
    Carsten Framme
    University Eye Hospital Regensburg, Franz Josef Strauss Allee 11, 93042 Regensburg, Germany
    Lasers Surg Med 34:206-15. 2004
    ..It was the aim of the study to investigate the influence of pulse duration and number of pulses on angiographically and ophthalmoscopically visible retinal damage thresholds in order to optimize treatment modalities...
  18. ncbi request reprint [Fundus autofluorescence after selective RPE laser treatment]
    C Framme
    Klinik und Poliklinik für Augenheilkunde, Klinikum der Universitat Regensburg, Germany
    Ophthalmologe 99:854-60. 2002
    ..The aim of the study was to investigate whether fundus autofluorescence (AF), which is derived from the lipofuscin contained by the RPE cells, is changed due to the RPE damage, and thus may be used for non-invasive treatment control...
  19. ncbi request reprint Fundus autofluorescence in APMPPE in association with lyme disease
    Carsten Framme
    University Eye Hospital Regensburg, Germany
    Retina 22:653-7. 2002
  20. ncbi request reprint [The red eye]
    C Framme
    Univ Augenklinik Regensburg Franz Josef Strauss Allee 11 D 93042 Regensburg
    MMW Fortschr Med 145:55-6. 2003
  21. ncbi request reprint Evaluation of the new photosensitizer Tookad (WST09) for photodynamic vessel occlusion of the choroidal tissue in rabbits
    Carsten Framme
    Medical Laser Center Lübeck, Lubeck, Germany
    Invest Ophthalmol Vis Sci 47:5437-46. 2006
    ....
  22. ncbi request reprint Optoacoustic real-time dosimetry for selective retina treatment
    Georg Schuele
    Medical Laser Center, Lubeck, Germany
    J Biomed Opt 10:064022. 2005
    ..It detects the ophthalmoscopically invisible laser-induced damage of RPE cells and overcomes practical limitations of SRT for use in private practice...
  23. doi request reprint Selective retina therapy (SRT) in patients with geographic atrophy due to age-related macular degeneration
    Philipp Prahs
    University Eye Hospital Regensburg, Franz Josef Strauss Allee 11, 93042 Regensburg, Germany
    Graefes Arch Clin Exp Ophthalmol 248:651-8. 2010
    ..Herein, SRT was used to selectively treat these cells to stimulate RPE proliferation, in order to reduce or ideally stop further growth of the atrophic area...
  24. ncbi request reprint Fundus autofluorescence before and after photodynamic therapy for choroidal neovascularization secondary to age-related macular degeneration
    Carsten Framme
    University Eye Hospital Regensburg, Franz Josef Strauss Allee 11, 93042 Regensburg, Germany
    Ophthalmic Surg Lasers Imaging 37:406-14. 2006
    ..To describe fundus autofluorescence patterns in choroidal neovascularization secondary to age-related macular degeneration before and after photodynamic therapy (PDT)...
  25. ncbi request reprint Selective targeting of the retinal pigment epithelium in rabbit eyes with a scanning laser beam
    Carsten Framme
    Wellman Center for Photomedicine, Massachusetts General Hospital and Harvard Medical School, 185 Cambridge Street, Boston, MA 02114, USA
    Invest Ophthalmol Vis Sci 48:1782-92. 2007
    ..The selectivity of an alternative, more versatile scanning approach was examined in vivo by using a broad range of scanning parameters...
  26. pmc Retreatment of full-thickness macular hole: predictive value of optical coherence tomography
    Jost Hillenkamp
    Department of Ophthalmology, University of Regensburg, Franz Josef Strauss Allee 11, D 93042 Regensburg, Germany
    Br J Ophthalmol 91:1445-9. 2007
    ....
  27. ncbi request reprint RPE-rip after intravitreal bevacizumab (Avastin) treatment for vascularised PED secondary to AMD
    Maria Andreea Gamulescu
    University Eye Clinic, Franz Josef Strauss Allee 11, 93053 Regensburg, Germany
    Graefes Arch Clin Exp Ophthalmol 245:1037-40. 2007
    ..We report here on four patients that received intravitreal bevacizumab (Avastin) for AMD-associated vascularised PED and developed RPE-rips during the follow-up...
  28. ncbi request reprint Long-term safety and functional outcome of combined pars plana vitrectomy and scleral-fixated sutured posterior chamber lens implantation
    Gundula Bading
    University Eye Hospital Regensburg, Regensburg, Germany
    Am J Ophthalmol 144:371-377. 2007
    ..To investigate the complication profile and the long-term functional outcome of combined pars plana vitrectomy and scleral-fixated sutured posterior chamber lens (PC IOL) implantation...
  29. ncbi request reprint Immediate and long-term changes of fundus autofluorescence in continuous wave laser lesions of the retina
    Carsten Framme
    University Eye Hospital Regensburg, Regensburg, Germany
    Ophthalmic Surg Lasers Imaging 35:131-8. 2004
    ..To determine whether fundus autofluorescence imaging is able to show changes in retinal pigment epithelium (RPE) fluorescence after thermal laser photocoagulation...
  30. ncbi request reprint Correlation between optical coherence tomography and autofluorescence in acute posterior multifocal placoid pigment epitheliopathy
    Ahmed A R Souka
    Ophthalmology Department, University of Regensburg, Regensburg, Germany
    Graefes Arch Clin Exp Ophthalmol 244:1219-23. 2006
    ....
  31. doi request reprint Effects on choroidal neovascularization after anti-VEGF Upload using intravitreal ranibizumab, as determined by spectral domain-optical coherence tomography
    Carsten Framme
    University Eye Hospital, Regensburg, Germany
    Invest Ophthalmol Vis Sci 51:1671-6. 2010
    ..In this study, spectral domain-optical coherence tomography (SD-OCT) was used to image CNV structure before and after anti-VEGF treatment...
  32. doi request reprint Maintenance of adult porcine retina and retinal pigment epithelium in perfusion culture: characterisation of an organotypic in vitro model
    Karin Kobuch
    Department of Ophthalmology, University of Regensburg, Franz Josef Strauss Allee 11, D 93042 Regensburg, Germany
    Exp Eye Res 86:661-8. 2008
    ..It offers new perspectives for the safety testing of substances designed for intraocular application...
  33. ncbi request reprint Surgical removal of idiopathic epiretinal membrane with or without the assistance of indocyanine green: a randomised controlled clinical trial
    Jost Hillenkamp
    Department of Ophthalmology, University of Regensburg, Franz Josef Strauss Allee 11, 93042 Regensburg, Germany
    Graefes Arch Clin Exp Ophthalmol 245:973-9. 2007
    ..To carry out a prospective investigation of the functional and morphological outcome of idiopathic epiretinal membrane (IEM) surgery with or without the assistance of indocyanine green (ICG) in a randomised controlled clinical trial...
  34. ncbi request reprint Selective targeting of the retinal pigment epithelium using an acousto-optic laser scanner
    Clemens Alt
    Massachusetts General Hospital, Harvard Medical School, Wellman Center for Photomedicine, Boston, Massachusetts 02114, USA
    J Biomed Opt 10:064014. 2005
    ..Selective RPE damage is feasible by rapidly scanning a cw laser beam. The scanning device is an attractive alternative to conventional laser coagulation and pulsed laser targeting of the RPE...
  35. ncbi request reprint Noninvasive optoacoustic temperature determination at the fundus of the eye during laser irradiation
    Georg Schule
    Medical Laser Center Lübeck, Lubeck, Germany
    J Biomed Opt 9:173-9. 2004
    ..This technique can also be adapted to continuous-wave photocoagulation, photodynamic therapy and transpupillary thermotherapy, or other fields of laser-heated tissue...
  36. doi request reprint [Cost analysis of contrast-enhanced cranial MRI at a German university hospital]
    A G Schreyer
    Institut für Röntgendiagnostik, Universitatsklinikum Regensburg, Franz Josef Strauss Allee 11, Regensburg
    Rofo 182:891-9. 2010
    ..Detailed evaluation and cost analysis of a cranial contrast-enhanced MRI (c-ceMRI) in outpatients, inpatients, patients in an intensive care unit and children under anesthesia...
  37. ncbi request reprint Ascorbic acid modulates proliferation and extracellular matrix accumulation of hyalocytes
    Florian Sommer
    Department of Pharmaceutical Technology, University of Regensburg, Regensburg, Germany
    Tissue Eng 13:1281-9. 2007
    ..Taken together with the fact that ascorbic acid is present in high concentrations in the vitreous body, this vitamin seems to be an important factor for in vitro hyalocyte culture...
  38. doi request reprint Acute visual loss after preoperative embolization of an ethmoidal metastasis
    Karsten Hufendiek
    Department of Ophthalmology, University Medical Center Regensburg, Regensburg, Germany
    Int Ophthalmol 32:165-9. 2012
    ..Radiological intervention via the ophthalmic artery can result in complete loss of vision, even after limited and transient obstruction of the vessel...
  39. doi request reprint Different collagen types define two types of idiopathic epiretinal membranes
    Michaela Kritzenberger
    Institute of Human Anatomy and Embryology, University of Regensburg, Regensburg, Germany
    Histopathology 58:953-65. 2011
    ..To identify differences in extracellular matrix contents between idiopathic epiretinal membranes (IEM) of cellophane macular reflex (CMRM) or preretinal macular fibrosis (PMFM) type...
  40. ncbi request reprint RPE in perfusion tissue culture and its response to laser application. Preliminary report
    Carsten Framme
    University Eye Hospital Regensburg, Germany
    Ophthalmologica 216:320-8. 2002
    ..To study the effects of conventional laser application on the retinal pigment epithelium (RPE) in a perfusion tissue culture model of porcine retinal pigment epithelium without overlying neurosensory retina...
  41. ncbi request reprint Fundus autofluorescence in macular hole surgery
    C Framme
    University Eye Clinic, Regensburg, Germany
    Ophthalmic Surg Lasers 32:383-90. 2001
    ..The autofluorescence is helpful for the examination of pseudoforamina and might be useful for estimating therapeutic success...
  42. doi request reprint [Hospital quality management in Germany]
    C Framme
    Klinik und Poliklinik für Augenheilkunde, Universitat Regensburg
    Klin Monbl Augenheilkd 225:804-11. 2008
    ..Due to the increasing and effective privatisation of hospitals in Germany, careful attention to specially designed QM systems for private hospitals seems to be reasonable...
  43. ncbi request reprint [Transplantation of the submandibular gland in absolute dry eyes. Effect on the ocular surface]
    Christina Schroder
    Klinik für Augenheilkunde des Universitätsklinikums der Medizinischen Universität Lübeck, Germany
    Klin Monbl Augenheilkd 219:494-501. 2002
    ..We studied the effect of this salivary tear film on the ocular surface in a prospective controlled clinical study...
  44. ncbi request reprint Threshold determinations for selective retinal pigment epithelium damage with repetitive pulsed microsecond laser systems in rabbits
    Carsten Framme
    University Eye Clinic Regensburg, Germany
    Ophthalmic Surg Lasers 33:400-9. 2002
    ..Our purpose was to determine the ophthalmoscopic and angiographic damage thresholds as a function of pulse durations by using different pulsed laser systems to optimize treatment modalities...