Research Topics
| Frank A FlachskampfSummaryAffiliation: University of Erlangen-Nuremberg Country: Germany Publications
| Collaborators
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Detail Information
Publications
[3D echocardiography]F A Flachskampf
Universität Erlangen Nürnberg Med Klinik II mit Poliklinik
Z Kardiol 89:104-9. 2000..Furthermore, the advent of real-time 3D echo with its ability to gather the full 3D data set within seconds promises to widen the potential applications of 3D echo, for example, including stress echo...
Randomized trial of acupuncture to lower blood pressureFrank A Flachskampf
Med Klinik 2, Universitatsklinikum Erlangen, Ulmenweg 18, 91054 Erlangen, Germany
Circulation 115:3121-9. 2007..Pharmacological treatment has limitations resulting from drug side effects, costs, and patient compliance. Thus, we investigated whether traditional Chinese medicine acupuncture is able to lower blood pressure...
[Aortic valve stenosis]F A Flachskampf
Medizinische Klinik II, Universitatsklinikum Erlangen
Internist (Berl) 45:1281-90; quiz 1291-2. 2004..Truly asymptomatic patients with preserved left ventricular function should be followed conservatively...
CON: The incidental finding of a patent foramen ovale during cardiac surgery: should it always be repaired?Frank A Flachskampf
Med Klinik 2, University of Erlangen, Erlangen, Germany
Anesth Analg 105:613-4. 2007
Assessment of aortic dissection and hematomaFrank A Flachskampf
Med Klinik 2, Universitatsklinikum Erlangen, Germany
Semin Cardiothorac Vasc Anesth 10:83-8. 2006..Aortic intramural hematoma is often a precursor of classic dissection or accompanies it and can also be diagnosed by TEE, although the diagnosis is frequently difficult...
Echocardiographic methods to select candidates for cardiac resynchronisation therapyFrank A Flachskampf
Med.Klinik 2, University of Erlangen, Germany
Heart 92:424-9. 2006
[Diagnostic value of tissue Doppler parameters in the early diagnosis of cardiomyopathies]Frank A Flachskampf
Medizinische Klinik 2 Kardiologie Angiologie, Universitatsklinikum Erlangen, Ulmenweg 18, 91054, Erlangen, Germany
Herz 32:89-96. 2007..However, lack of measurement standardization and small numbers of cardiomyopathy patients examined by Doppler, together with difficulty in defining reliable normalcy ranges, still hamper widespread clinical use of this new tool...
Aortic dissectionF A Flachskampf
Medizinische Klinik II, Universitat Erlangen Nurnberg, Germany
Cardiol Clin 18:807-17, ix. 2000..Dissection of the ascending aorta, which has an extremely high mortality and necessitates emergency surgery, is diagnosed quickly and accurately by TEE...
[Why controlled studies may lead to misleading and unconfirmed therapeutic concepts--a critical view of evidence-based medicine]F A Flachskampf
Med Klinik II mit Poliklinik Ostliche Stadtmauerstr 29, 91054 Erlangen, Germany
Z Kardiol 91:197-202. 2002....
[Mitral regurgitation]F A Flachskampf
Medizinische Klinik II, Universitatsklinikum Erlangen, Erlangen
Internist (Berl) 47:275-283; quiz 284-5. 2006..If possible, valve repair is preferred over valve replacement to better preserve left ventricular function and to avoid the need for postoperative anticoagulation (except if atrial fibrillation persists)...
The standard TEE examination: procedure, safety, typical cross-sections and anatomic correlations, and systematic analysisFrank A Flachskampf
Med Klinik 2, Erlangen, Germany
Semin Cardiothorac Vasc Anesth 10:49-56. 2006..A set of cross-sections, defined by anatomic landmarks, has been compiled, which can be systematically sought, evaluated, and modified according to the clinical question in order to extract the maximal information from TEE...
Comparison of deformation imaging and velocity imaging for detecting regional inducible ischaemia during dobutamine stress echocardiographyJens Uwe Voigt
Medizinische Klinik II, Friedrich Alexander Universitat Erlangen Nurnberg, Ulmenweg 18, 91054 Erlangen, Germany
Eur Heart J 25:1517-25. 2004..To determine whether Doppler based myocardial tissue velocity imaging (TVI) or strain rate imaging (SRI) is more accurate in detecting stress-induced ischaemia during dobutamine stress echocardiography (DSE)...
[Role of deformation imaging in diagnosing myocardial ischemia]Frank A Flachskampf
Medizinische Klinik 2, Universitatsklinikum Erlangen, Erlangen
Herz 33:122-8. 2008..Due to rapid evolution of these techniques, a final assessment of their potential is not possible yet...
Three-dimensional echocardiography: rational mode of component images for left ventricular volume quantitationUwe Nixdorff
2nd Medical Clinic, University of Erlangen Nuremberg, Erlangen, Germany
Cardiology 104:76-82. 2005..The most rational component image analysis for 3DE volumetry in the in vitro model uses short-axis slices with a thickness of 15 mm...
Short-term prognosis of contemporary interventional therapy of ST-elevation myocardial infarction: does gender matter?Stefan Zimmermann
Medizinische Klinik 2 Kardiologie Angiologie, Universitatsklinikum Erlangen, 91054 Erlangen, Germany
Clin Res Cardiol 98:709-15. 2009..We set out to analyze whether there are gender differences in real-world contemporary treatment and outcomes of STEMI...
Incidence and characteristics of segmental postsystolic longitudinal shortening in normal, acutely ischemic, and scarred myocardiumJens Uwe Voigt
Medizinische Klinik II, Friedrich Alexander Universitat Erlangen Nurnberg, Germany
J Am Soc Echocardiogr 16:415-23. 2003..However, PSS can also occur in healthy subjects. We, therefore, investigated the occurrence and characteristics of PSS in control subjects and patients, and how to distinguish normality from disease...
Direct coronary stenting versus predilatation followed by stent placementMartin Brueck
University of Erlangen Nuernberg, Department of Cardiology, Erlangen, Germany
Am J Cardiol 90:1187-92. 2002....
Real-time myocardial contrast stress echocardiography using bolus applicationGerald H Wasmeier
The 2nd Medical Clinic, University of Erlangen Nuremberg, Erlangen, Germany
Ultrasound Med Biol 34:1724-31. 2008..Very high negative predictive values favour the potential of the method in excluding the diagnosis. Further need of research work may be encouraged by those findings...
Practicability and limitations of enhanced external counterpulsation as an additional treatment for anginaDierk Werner
Department of Cardiology, Friedrich Alexander University Erlangen Nuremberg, Erlangen, Germany
Clin Cardiol 26:525-9. 2003..However, given the wide range of contraindications and the long duration of treatment, eligibility and practicality issues have not been addressed systematically...
Strain-rate imaging during dobutamine stress echocardiography provides objective evidence of inducible ischemiaJens Uwe Voigt
Medizinische Klinik II, Friedrich Alexander Universitat Erlangen Nurnberg, Ulmenweg 18, 91054 Erlangen, Germany
Circulation 107:2120-6. 2003..Strain-rate imaging (SRI) by tissue Doppler may objectively analyze regional myocardial function. This study investigated SRI markers of stress-induced ischemia and analyzed their applicability in a clinical setting...
Outcomes of contemporary interventional therapy of ST elevation infarction in patients older than 75 yearsStefan Zimmermann
Med Klinik 2, Universitatsklinikum Erlangen, 91054 Erlangen, Germany
Clin Cardiol 32:87-93. 2009..Data on contemporary real-world outcomes of interventional revascularization in patients > or = 75 y of age with ST elevation infarction (STEMI) are limited...
Sequential changes in myocardial function after valve replacement for aortic stenosis by speckle tracking echocardiographyChristian Rost
University of Erlangen, Erlangen, Germany
Eur J Echocardiogr 11:584-9. 2010..Speckle tracking echocardiography (STE) was applied to evaluate longitudinal, radial, and circumferential function in patients with aortic stenosis (AS) before, within 1 week, and 6 months after aortic valve replacement (AVR)...
Influence of ultrasound operating parameters on ultrasound-induced thrombolysis in vitroSimon Schäfer
Med Klinik II, Universitatsklinikum Erlangen, Erlangen, Germany
Ultrasound Med Biol 31:841-7. 2005..86) and a modest direct effect of pulse length (r(2) = 0.57, p < 10(-5)). Thus, thrombolytic efficiency of US depends directly on duration, intensity, duty cycle and pulse length and inversely, on frequency...
Recommendations for chamber quantificationRoberto M Lang
Med. Klinik 2, Erlangen University, Ulmenweg 18, 91054 Erlangen, Germany
Eur J Echocardiogr 7:79-108. 2006..This document reviews the technical aspects on how to perform quantitative chamber measurements of morphology and function, which is a component of every complete echocardiographic examination...
Assessment of coronary remodeling in stenotic and nonstenotic coronary atherosclerotic lesions by multidetector spiral computed tomographyStephan Achenbach
Department of Radiology, Massachusetts General Hospital, Boston, MA, USA
J Am Coll Cardiol 43:842-7. 2004..This study was designed to investigate whether contrast-enhanced multidetector spiral CT (MDCT) permits assessment of remodeling in coronary atherosclerotic lesions...
Images in cardiovascular medicine. Giant true aneurysms of saphenous vein bypass grafts: a rare cause of tumor-like mediastinal massesDieter Ropers
Department of Internal Medicine II, University of Erlangen-Nuremberg, Germany
Circulation 109:e322-3. 2004
Recommendations for transoesophageal echocardiography: update 2010F A Flachskampf
Med Klinik 2, University of Erlangen, Erlangen, Germany
Eur J Echocardiogr 11:557-76. 2010....
[Echocardiography to optimize patient selection for cardiac resynchronization therapy]O-A Breithardt
Medizinische Klinik 2,
Dtsch Med Wochenschr 132:762-7. 2007
[Aortic stenosis]W G Daniel
Med. Klinik 2, , Ulmenweg 18, 91054, Erlangen, Germany
Clin Res Cardiol 95:620-41. 2006
Dose-dependent disintegration of human endothelial monolayers by contrast echocardiographyU Nixdorff
2nd Medical Clinic, Friedrich Alexander University, Erlangen Nuremberg, Germany
Life Sci 77:1493-501. 2005..Diagnostic contrast echocardiography may induce endothelial disintegrations dependent on US output as well as on CA concentrations. This aspect might be helpful in further in vivo series on local drug delivery...
Transradial stenting of the iliac artery: a case reportFrank A Flachskampf
Department of Cardiology, University Clinic Erlangen, Erlangen, Germany
Catheter Cardiovasc Interv 65:193-5. 2005..Radial access avoids bleeding and ischemia that may complicate retrograde or crossover access to the iliac artery...
Strain rate imaging for the assessment of preload-dependent changes in regional left ventricular diastolic longitudinal functionJens Uwe Voigt
Medical Clinic II, University Erlangen Nuernberg, Erlangen, Germany
J Am Soc Echocardiogr 15:13-9. 2002..A base-to-apex time delay in diastolic lengthening could be seen both in early diastole and at atrial contraction...
Sequential vs. kissing balloon angioplasty for stenting of bifurcation coronary lesionsMartin Brueck
Department of Cardiology, University of Erlangen Nuremberg, Erlangen, Germany
Catheter Cardiovasc Interv 55:461-6. 2002..Kissing balloon angioplasty reduces the rate of transient side-branch occlusion compared to sequential PTCA but does not improve immediate or long-term outcome compared to sequential PTCA for stenting of bifurcation lesions...
[The procedure of echocardiographic tests]G H Wasmeier
, Medizinische Klinik 2, , Ulmenweg 18, 91054 Erlangen
Dtsch Med Wochenschr 133:595-8. 2008
Closure of patent foramen ovale: is the case really closed as well?F A Flachskampf
Medizinische Klinik II, Universitätsklinik Erlangen, Erlangen, Germany
Heart 91:449-50. 2005
Transradial approach for coronary angioplasty in the setting of acute myocardial infarction: a dual-center registryYves Louvard
Institut Cardiovasculaire Paris Sud, Institut Hospitalier Jacquer Cartier, 6 avenue du Noyer Lambert, 91300 Massy, France
Catheter Cardiovasc Interv 55:206-11. 2002....
How to diagnose diastolic heart failure: a consensus statement on the diagnosis of heart failure with normal left ventricular ejection fraction by the Heart Failure and Echocardiography Associations of the European Society of CardiologyWalter J Paulus
Laboratory of Physiology, VU University Medical Center, Van der Boechorststraat, 7, 1081 BT, Amsterdam, The Netherlands
Eur Heart J 28:2539-50. 2007..The updated strategies for the diagnosis and exclusion of HFNEF are useful not only for individual patient management but also for patient recruitment in future clinical trials exploring therapies for HFNEF...
Are there sex differences in regional systolic function and wall stress in hypertrophic obstructive cardiomyopathy? A three-dimensional echocardiography studyJürgen Frielingsdorf
Cardiology, Department of Medicine, City Hospital Triemli, Zurich, Switzerland
J Am Soc Echocardiogr 17:638-43. 2004..The goal of this study was to determine systolic function of the LV in male and female patients with hypertrophic obstructive cardiomyopathy and to relate it to wall thickness and wall stress, respectively...
Early failure of a mechanical bileaflet aortic valve prosthesis due to pannus: a rare complicationMarkus Kondruweit
Center of Cardiac Surgery, Friedrich-Alexander-University, Erlangen-Nuremberg, Germany
J Thorac Cardiovasc Surg 136:213-4. 2008
Severe aortic stenosis with low gradient and apparently preserved left ventricular systolic function--under-recognized or overdiagnosed?Frank A Flachskampf
Eur Heart J 29:966-8. 2008
Do women have impaired regional systolic function in hypertensive heart disease? A 3-dimensional echocardiography studyJürgen Frielingsdorf
Heart Center, City Hospital Triemli, Birmensdorferstrasse 497, 8063 Zurich, and Cardiology, University Hospital, Bern, Switzerland
Eur J Echocardiogr 8:42-7. 2007..The goal of this study was to determine regional systolic function of the left ventricle in male and female patients with hypertensive heart disease...
Determination of stenotic mitral valve area: new, old, and gold standardsFrank A Flachskampf
Eur J Echocardiogr 9:321; author reply 321-2. 2008
Real-time myocardial contrast echocardiography for assessing perfusion and function in healthy and infarcted wistar ratsGerald H Wasmeier
Second Medical Clinic, Friedrich Alexander University, Erlangen Nuremberg, Germany
Ultrasound Med Biol 34:47-55. 2008..838). These data confirmed high-resolution real-time MCE as a rational tool for assessing myocardial perfusion of Wistar rats. It may therefore be a useful diagnostic tool for in-vivo cardiovascular research in small animals...
Reproducibility of transthoracic echocardiography in small animals using clinical equipmentGerald H Wasmeier
2nd Medical Clinic, Friedrich Alexander University, Erlangen Nuremberg, University Hospital Hamburg Eppendorf, Germany
Coron Artery Dis 18:283-91. 2007....
Recommendations for chamber quantification: a report from the American Society of Echocardiography's Guidelines and Standards Committee and the Chamber Quantification Writing Group, developed in conjunction with the European Association of EchocardiographRoberto M Lang
University of Chicago Hospitals, Chicago, IL, USA
J Am Soc Echocardiogr 18:1440-63. 2005
Head-to-head comparison of dobutamine stress echocardiography and cardiac computed tomography for the detection of significant coronary artery diseaseUwe Nixdorff
Leibniz Institute of Arteriosclerosis Research, Westfalische Wilhelms University, Munster, Germany
Cardiology 110:81-6. 2008..We compared the accuracy of both methods to detect significant CAD in a direct comparison...
